JP2019004912A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2019004912A5 JP2019004912A5 JP2018196337A JP2018196337A JP2019004912A5 JP 2019004912 A5 JP2019004912 A5 JP 2019004912A5 JP 2018196337 A JP2018196337 A JP 2018196337A JP 2018196337 A JP2018196337 A JP 2018196337A JP 2019004912 A5 JP2019004912 A5 JP 2019004912A5
- Authority
- JP
- Japan
- Prior art keywords
- hours
- culture medium
- embryo
- mammalian
- mammal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000001963 growth medium Substances 0.000 claims 7
- 210000001161 mammalian embryo Anatomy 0.000 claims 7
- 241000124008 Mammalia Species 0.000 claims 4
- 210000001109 blastomere Anatomy 0.000 claims 4
- 239000002609 medium Substances 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 2
- 238000012258 culturing Methods 0.000 claims 2
- 230000001939 inductive effect Effects 0.000 claims 2
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 210000002257 embryonic structure Anatomy 0.000 claims 1
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US90297007P | 2007-02-23 | 2007-02-23 | |
| US60/902,970 | 2007-02-23 | ||
| US91854307P | 2007-03-16 | 2007-03-16 | |
| US60/918,543 | 2007-03-16 | ||
| US99377207P | 2007-09-14 | 2007-09-14 | |
| US60/993,772 | 2007-09-14 | ||
| US943207P | 2007-12-28 | 2007-12-28 | |
| US61/009,432 | 2007-12-28 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016119245A Division JP6423386B2 (ja) | 2007-02-23 | 2016-06-15 | 分化した細胞の再プログラムおよび再プログラムされた細胞からの動物および胚幹細胞の生成のための高能率的な方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019004912A JP2019004912A (ja) | 2019-01-17 |
| JP2019004912A5 true JP2019004912A5 (enExample) | 2019-06-20 |
Family
ID=39710674
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009550931A Pending JP2010518857A (ja) | 2007-02-23 | 2008-02-22 | 分化した細胞の再プログラムおよび再プログラムされた細胞からの動物および胚幹細胞の生成のための高能率的な方法 |
| JP2013097811A Active JP5955809B2 (ja) | 2007-02-23 | 2013-05-07 | 分化した細胞の再プログラムおよび再プログラムされた細胞からの動物および胚幹細胞の生成のための高能率的な方法 |
| JP2016119245A Active JP6423386B2 (ja) | 2007-02-23 | 2016-06-15 | 分化した細胞の再プログラムおよび再プログラムされた細胞からの動物および胚幹細胞の生成のための高能率的な方法 |
| JP2018196337A Pending JP2019004912A (ja) | 2007-02-23 | 2018-10-18 | 分化した細胞の再プログラムおよび再プログラムされた細胞からの動物および胚幹細胞の生成のための高能率的な方法 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009550931A Pending JP2010518857A (ja) | 2007-02-23 | 2008-02-22 | 分化した細胞の再プログラムおよび再プログラムされた細胞からの動物および胚幹細胞の生成のための高能率的な方法 |
| JP2013097811A Active JP5955809B2 (ja) | 2007-02-23 | 2013-05-07 | 分化した細胞の再プログラムおよび再プログラムされた細胞からの動物および胚幹細胞の生成のための高能率的な方法 |
| JP2016119245A Active JP6423386B2 (ja) | 2007-02-23 | 2016-06-15 | 分化した細胞の再プログラムおよび再プログラムされた細胞からの動物および胚幹細胞の生成のための高能率的な方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8796021B2 (enExample) |
| EP (3) | EP3190178A1 (enExample) |
| JP (4) | JP2010518857A (enExample) |
| KR (1) | KR20100014504A (enExample) |
| CN (2) | CN105441385A (enExample) |
| AU (1) | AU2008218998A1 (enExample) |
| CA (1) | CA2679109C (enExample) |
| HK (1) | HK1222887A1 (enExample) |
| IL (1) | IL200522A (enExample) |
| WO (1) | WO2008103462A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3015835A1 (en) | 2004-11-04 | 2006-05-18 | Astellas Institute For Regenerative Medicine | Derivation of embryonic stem cells |
| US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| CA2659945C (en) | 2005-08-03 | 2014-12-16 | Advanced Cell Technology, Inc. | Improved methods of reprogramming animal somatic cells |
| EP3190178A1 (en) * | 2007-02-23 | 2017-07-12 | Astellas Institute for Regenerative Medicine | Highly efficient methods for reprogramming differentiated cells and for generating animals and embryonic stem cells from reprogrammed cells |
| EP2283118A4 (en) | 2008-05-06 | 2012-11-21 | Agency Science Tech & Res | METHOD FOR LEARNING THE DEDIFFERENCING OF A CELL |
| CN101798569B (zh) * | 2009-02-09 | 2012-11-21 | 北京瑞途之星科技有限公司 | 以卵裂后的发育胚胎替代卵母细胞的治疗性克隆新方法 |
| AU2011235212B2 (en) * | 2010-03-31 | 2014-07-31 | The Scripps Research Institute | Reprogramming cells |
| CN101921808B (zh) * | 2010-08-18 | 2012-05-30 | 东北农业大学 | 一种提高猪体细胞核移植效率的方法 |
| US20120184035A1 (en) * | 2011-01-13 | 2012-07-19 | Sadhana Agarwal | Methods and Compositions For Reprogramming Cells |
| WO2012174086A1 (en) * | 2011-06-14 | 2012-12-20 | J. R. Simplot Company | A method for identifying a mammal receptive to embryo transfer |
| WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
| CN102321571A (zh) * | 2011-09-21 | 2012-01-18 | 王跃嗣 | 从分化细胞制备自体造血干细胞的方法 |
| KR102108245B1 (ko) | 2011-11-30 | 2020-05-08 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 중간엽 간질 세포 및 이에 관련된 용도 |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| US9428732B2 (en) * | 2011-12-05 | 2016-08-30 | Primorigen Biosciences, Inc. | Compositions and methods for differentiating pluripotent stem cells into primitive blood cells and uses thereof |
| US9179935B2 (en) * | 2012-01-13 | 2015-11-10 | The Board Of Trustees Of The Leland Stanford Junior University | Mechanical biomarkers for oocyte and embryo viability |
| CN102608323A (zh) * | 2012-03-26 | 2012-07-25 | 西北农林科技大学 | 一种基于哺乳动物囊胚的分子免疫检测的胚胎质量分析方法 |
| CN104471059B (zh) | 2012-07-12 | 2018-04-17 | 珠海横琴爱姆斯坦生物科技有限公司 | 人胚胎干细胞衍生的间充质样干细胞、方法及其应用 |
| WO2014144754A1 (en) | 2013-03-15 | 2014-09-18 | The New York Stem Cell Foundation | Somatic cell nuclear transfer methods |
| JP6689498B2 (ja) * | 2013-04-16 | 2020-04-28 | イーエムべーアー−インスティツート フューア モレクラー ビオテクノロギー ゲーエムベーハー | ブラストイド、細胞株に基づく人工胚盤胞 |
| JP2016073207A (ja) * | 2014-10-02 | 2016-05-12 | 株式会社リプロセル | 細胞凍結保存方法、細胞解凍方法、及び細胞 |
| EP4343331A3 (en) | 2015-03-23 | 2024-06-19 | Astellas Institute for Regenerative Medicine | Improved assays for potency of human retinal pigment epithelium (rpe) cells and photoreceptor progenitors |
| CA3019574C (en) * | 2016-03-31 | 2025-09-23 | Sanbio Inc | Medium, methods, cells and secreted factors for stem cell culture and therapy |
| US20180127738A1 (en) * | 2016-11-07 | 2018-05-10 | BiomediStem, LLC | Production and therapeutic uses of epinul pluripotent cells and differentiated cells derived therefrom |
| EP3824906A1 (en) | 2016-12-21 | 2021-05-26 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| CN107099553A (zh) * | 2017-06-19 | 2017-08-29 | 内蒙古大学 | 一种小鼠体细胞核移植方法 |
| CA3076500C (en) * | 2017-09-21 | 2025-07-08 | Emulate Inc | REOLOGICALLY BIOMIMITED FLUID SUBSTITUTE |
| CN108624621B (zh) * | 2018-01-17 | 2019-04-12 | 中国科学院上海生命科学研究院 | 非人灵长类的体细胞克隆动物的制备方法 |
| CN110819585B (zh) * | 2018-08-09 | 2022-12-06 | 山东大学 | 含有igf2的胚胎体外培育方法和培养基 |
| TWI715874B (zh) * | 2018-09-27 | 2021-01-11 | 台灣粒線體應用技術股份有限公司 | 無血清培養液以及使用此無血清培養液分離和放大培養幹細胞方法 |
| EP3870188B1 (en) * | 2018-10-23 | 2024-06-19 | The Board of Trustees of the Leland Stanford Junior University | Prevention and treatment of teratoma formation in stem cell-based thereapies using alternating electric fields |
| US20250263654A1 (en) * | 2021-06-25 | 2025-08-21 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David | Primordial germ cells |
| CN113925878B (zh) * | 2021-10-20 | 2024-03-08 | 上海交通大学医学院附属仁济医院 | 一种细胞外囊泡在治疗神经损伤性勃起功能障碍中的应用 |
| CN114128668A (zh) * | 2021-11-24 | 2022-03-04 | 华中农业大学 | 一种提高水牛夏季同期发情-定时输精效果的处理方法 |
| WO2025206342A1 (ja) * | 2024-03-29 | 2025-10-02 | 学校法人順天堂 | 組織幹細胞の老化抑制剤 |
| CN119120577A (zh) * | 2024-11-14 | 2024-12-13 | 内蒙古大学 | 一种擦除羊iCHI胚胎表观修饰异常的方法及其应用 |
| CN119639658B (zh) * | 2025-02-18 | 2025-07-15 | 中国农业大学 | 促进胚胎体外发育的组合物、培养液、产品及方法 |
| CN119752781B (zh) * | 2025-03-04 | 2025-07-01 | 中国农业大学 | 缓解成熟卵子老化的组合物、培养液、产品及方法 |
Family Cites Families (63)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4441972A (en) | 1983-04-08 | 1984-04-10 | D.E.P. Systems, Inc. | Apparatus for electrofusion of biological particles |
| US4664097A (en) | 1984-05-09 | 1987-05-12 | The Wistar Institute Of Anatomy & Biology | Nuclear transplantation in the mammalian embryo by microsurgery and cell fusion |
| US4578168A (en) | 1984-07-27 | 1986-03-25 | Biotronics | Apparatus for fusing live cells with electric fields |
| US4994384A (en) | 1986-12-31 | 1991-02-19 | W. R. Grace & Co.-Conn. | Multiplying bovine embryos |
| US5057420A (en) | 1987-06-05 | 1991-10-15 | Granada Biosciences, Inc. | Bovine nuclear transplantation |
| US5213979A (en) | 1987-12-30 | 1993-05-25 | W. R. Grace & Co.-Conn. | In vitro culture of bovine embryos |
| EP0435928A1 (en) | 1988-09-21 | 1991-07-10 | Animal Biotechnology Cambridge Limited | Derivation of pluripotential embryonic cell lines from domestic animals |
| US4944384A (en) | 1989-01-30 | 1990-07-31 | Hay & Forage Industries | Trash discharge apparatus for crop transferring conveyor mechanism |
| CA2086330A1 (en) | 1990-07-09 | 1992-01-10 | Richard C. Fry | Enhanced implantation, development and maintenance of embryos using leukaemia inhibitory factor |
| US5096822A (en) | 1990-07-26 | 1992-03-17 | W. R. Grace & Co.- Conn. | Bovine embryo medium |
| JP3104995B2 (ja) | 1991-01-31 | 2000-10-30 | ワーナー−ランバート・コンパニー | 抗炎症剤として有用な4,6−ジ−第三ブチル−5−ヒドロキシ−1,3−ピリミジンの置換されたヘテロアリール類似体 |
| US5173158A (en) | 1991-07-22 | 1992-12-22 | Schmukler Robert E | Apparatus and methods for electroporation and electrofusion |
| US5496720A (en) | 1993-02-10 | 1996-03-05 | Susko-Parrish; Joan L. | Parthenogenic oocyte activation |
| GB9308271D0 (en) | 1993-04-21 | 1993-06-02 | Univ Edinburgh | Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method |
| US5523226A (en) | 1993-05-14 | 1996-06-04 | Biotechnology Research And Development Corp. | Transgenic swine compositions and methods |
| AU1439295A (en) | 1993-12-17 | 1995-07-03 | Abs Global, Inc. | Ungulate preblastocyst derived embryonic stem cells and use thereof to produce cloned transgenic and chimeric ungulates |
| EP0739412B1 (en) | 1993-12-23 | 2002-02-27 | Infigen, Inc. | ungulate EMBRYONIC STEM CELLS AS NUCLEAR DONORS AND NUCLEAR TRANSFER TECHNIQUES TO PRODUCE CHIMERIC AND TRANSGENIC ANIMALS |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US7696404B2 (en) * | 1996-08-19 | 2010-04-13 | Advanced Cell Technology, Inc. | Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions |
| US20090092588A1 (en) * | 1997-01-10 | 2009-04-09 | University Of Massachusetts As Represented By Its Amherst Campus | Cloned ungulate embryos and animals, use of cells, tissues and organs thereof for transplantation therapies including parkinson's disease |
| US5945577A (en) | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
| NZ337495A (en) | 1997-03-06 | 2001-06-29 | Infigen Inc | Bovine primordial germ cells and their use in cloning |
| US6011197A (en) * | 1997-03-06 | 2000-01-04 | Infigen, Inc. | Method of cloning bovines using reprogrammed non-embryonic bovine cells |
| US6667176B1 (en) * | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
| US6372494B1 (en) * | 1999-05-14 | 2002-04-16 | Advanced Tissue Sciences, Inc. | Methods of making conditioned cell culture medium compositions |
| US20040199935A1 (en) | 1999-06-30 | 2004-10-07 | Chapman Karen B. | Cytoplasmic transfer to de-differentiate recipient cells |
| EP1196426A4 (en) * | 1999-06-30 | 2003-09-03 | Advanced Cell Tech Inc | CYTOPLASMATIC TRANSFER FOR DE-DIFFERENTIATION OF VASCELL CELLS |
| CA2387488A1 (en) | 1999-10-14 | 2001-04-19 | James M. Robl | Preparation and selection of donor cells for nuclear transplantation |
| BR0014864A (pt) | 1999-10-15 | 2002-11-19 | Advanced Cell Tech Inc | Métodos de produzir células progenitoras diferenciadas e células tronco embriÈnicas defeituosas em linhagem |
| CN1425064A (zh) | 1999-12-20 | 2003-06-18 | 马萨诸塞大学 | 通过交叉物种核移植制备的胚胎或干样细胞 |
| CA2394812A1 (en) | 1999-12-20 | 2001-06-28 | Anthony C.F. Perry | A method to produce cloned embryos and adults from cultured cells |
| WO2001050848A2 (en) | 2000-01-07 | 2001-07-19 | Oregon Health And Science University | Clonal propagation of primate offspring by embryo splitting |
| DE10108412B4 (de) * | 2001-02-21 | 2006-03-09 | Cevec Pharmaceuticals Gmbh | Pigmentepithelzelle des Auges, ihre Herstellung und Verwendung in der Therapie einer Augen- oder Nervenerkrankung |
| IL160507A0 (en) | 2001-08-24 | 2004-07-25 | Advanced Cell Tech Inc | Screening assays for identifying differentiation-inducing agents and production of differentiated cells for cell therapy |
| US20030044976A1 (en) * | 2001-08-27 | 2003-03-06 | Advanced Cell Technology | De-differentiation and re-differentiation of somatic cells and production of cells for cell therapies |
| JP2003067271A (ja) * | 2001-08-27 | 2003-03-07 | Hitachi Ltd | 統合管理システム |
| WO2003018767A2 (en) | 2001-08-27 | 2003-03-06 | Advanced Cell Technology, Inc. | Trans-differentiation and re-differentiation of somatic cells and production of cells for cell therapies |
| WO2003046141A2 (en) | 2001-11-26 | 2003-06-05 | Advanced Cell Technology, Inc. | Methods for making and using reprogrammed human somatic cell nuclei and autologous and isogenic human stem cells |
| WO2003057836A2 (en) | 2001-12-27 | 2003-07-17 | Advanced Cell Technology, Inc. | Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions |
| US7247477B2 (en) | 2002-04-16 | 2007-07-24 | Technion Research & Development Foundation Ltd. | Methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells |
| AU2003233679A1 (en) | 2002-05-23 | 2003-12-12 | Advanced Cell Technology, Inc. | Generation of histocompatible tissues using nuclear transplantation |
| US7612250B2 (en) | 2002-07-29 | 2009-11-03 | Trustees Of Tufts College | Nuclear transfer embryo formation method |
| JP4374419B2 (ja) | 2002-10-31 | 2009-12-02 | 独立行政法人理化学研究所 | 多能性幹細胞培養用の組成物とその使用 |
| AU2003296480A1 (en) * | 2002-12-10 | 2004-06-30 | The Wistar Institute | Method for programmed differentiation of stem cells |
| EP2457999B1 (en) | 2002-12-16 | 2018-10-17 | Technion Research & Development Foundation Ltd. | Culture medium for pluripotent stem cells |
| US20040229350A1 (en) * | 2003-05-12 | 2004-11-18 | Nikolai Strelchenko | Morula derived embryonic stem cells |
| US20050118713A1 (en) * | 2003-05-12 | 2005-06-02 | Nikolai Strelchenko | Morula derived embryonic stem cells |
| TW200521236A (en) * | 2003-12-22 | 2005-07-01 | Animal Technology Inst Taiwan | Method for generating non-human mammalian chimeric embryo |
| SG188122A1 (en) | 2004-01-23 | 2013-03-28 | Advanced Cell Tech Inc | Improved modalities for the treatment of degenerative diseases of the retina |
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| WO2005080551A2 (en) | 2004-02-12 | 2005-09-01 | University Of Newcastle Upon Tyne | Stem cells |
| WO2006013519A1 (en) | 2004-07-26 | 2006-02-09 | Koninklijke Philips Electronics N.V. | Method of storing data in an information carrier, system for reading such an information carrier. |
| US20080262321A1 (en) | 2004-08-06 | 2008-10-23 | Ramot At Tel Aviv University Ltd. | Early Detection of Harmful Agents: Method, System and Kit |
| CA3015835A1 (en) * | 2004-11-04 | 2006-05-18 | Astellas Institute For Regenerative Medicine | Derivation of embryonic stem cells |
| US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| CA2659945C (en) | 2005-08-03 | 2014-12-16 | Advanced Cell Technology, Inc. | Improved methods of reprogramming animal somatic cells |
| WO2007047894A2 (en) | 2005-10-20 | 2007-04-26 | Advanced Cell Technology, Inc. | Totipotent, nearly totipotent or pluripotent mammalian cells homozygous or hemizygous for one or more histocompatibility antigen genes |
| US20080070303A1 (en) | 2005-11-21 | 2008-03-20 | West Michael D | Methods to accelerate the isolation of novel cell strains from pluripotent stem cells and cells obtained thereby |
| WO2007058671A1 (en) | 2005-11-21 | 2007-05-24 | West Michael D | Novel uses of cells with prenatal patterns of gene expression |
| KR101602951B1 (ko) | 2006-05-03 | 2016-03-14 | 오카타 세라퓨틱스, 인크. | 배아 줄기 세포 및 배-유도 세포의 유도 |
| CN100465268C (zh) * | 2006-05-17 | 2009-03-04 | 北京大学 | 人胚胎干细胞的培养方法及其专用培养基 |
| US20070298496A1 (en) * | 2006-06-23 | 2007-12-27 | Hung-Chih Kuo | Method of deriving pluripotent stem cells from a single blastomere |
| EP3190178A1 (en) | 2007-02-23 | 2017-07-12 | Astellas Institute for Regenerative Medicine | Highly efficient methods for reprogramming differentiated cells and for generating animals and embryonic stem cells from reprogrammed cells |
-
2008
- 2008-02-22 EP EP16183074.0A patent/EP3190178A1/en not_active Withdrawn
- 2008-02-22 AU AU2008218998A patent/AU2008218998A1/en not_active Abandoned
- 2008-02-22 KR KR1020097019691A patent/KR20100014504A/ko not_active Ceased
- 2008-02-22 US US12/528,212 patent/US8796021B2/en active Active
- 2008-02-22 WO PCT/US2008/002380 patent/WO2008103462A2/en not_active Ceased
- 2008-02-22 EP EP08725969A patent/EP2121902A4/en not_active Withdrawn
- 2008-02-22 CN CN201510660811.9A patent/CN105441385A/zh active Pending
- 2008-02-22 JP JP2009550931A patent/JP2010518857A/ja active Pending
- 2008-02-22 EP EP15164113.1A patent/EP2982744A1/en not_active Withdrawn
- 2008-02-22 CA CA2679109A patent/CA2679109C/en active Active
- 2008-02-22 CN CN200880013190A patent/CN101679942A/zh active Pending
-
2009
- 2009-08-20 IL IL200522A patent/IL200522A/en active IP Right Grant
-
2013
- 2013-05-07 JP JP2013097811A patent/JP5955809B2/ja active Active
-
2014
- 2014-07-23 US US14/338,596 patent/US10584313B2/en active Active
-
2016
- 2016-06-15 JP JP2016119245A patent/JP6423386B2/ja active Active
- 2016-09-22 HK HK16111146.2A patent/HK1222887A1/zh unknown
-
2018
- 2018-10-18 JP JP2018196337A patent/JP2019004912A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2019004912A5 (enExample) | ||
| WO2015054526A3 (en) | Methods of mammalian retinal stem cell production and applications | |
| Correia et al. | Combining hypoxia and bioreactor hydrodynamics boosts induced pluripotent stem cell differentiation towards cardiomyocytes | |
| BR112015019950A2 (pt) | Método para gerar linhagem de células-tronco embrionárias (es) de rato, e, cultura in vitro | |
| JP2014519832A5 (enExample) | ||
| JP2016500260A5 (enExample) | ||
| JP2008518616A5 (enExample) | ||
| Ikonomou et al. | Derivation of endodermal progenitors from pluripotent stem cells | |
| JP2012110344A5 (enExample) | ||
| JP2016508726A5 (enExample) | ||
| JP2018518943A5 (enExample) | ||
| JP2009515558A5 (enExample) | ||
| CN114480259B (zh) | 一种诱导小鼠全能样干细胞的培养基及诱导方法 | |
| Heemskerk | Full of potential: Pluripotent stem cells for the systems biology of embryonic patterning | |
| JP2013510570A5 (enExample) | ||
| WO2017049240A8 (en) | Selection of pluripotent cells for production of fertile xy female mice | |
| NZ591812A (en) | Cell culture method to form aggregates | |
| WO2018046929A9 (en) | Methods and compositions for co-culturing pluripotent and extra-embryonic cells | |
| WO2015108944A3 (en) | Stem cell-derived hepatocytes in co-culture and uses thereof | |
| Oh et al. | In vitro embryogenesis and gastrulation using stem cells in mice and humans | |
| ATE375385T1 (de) | Verwendung eines serumfreien zellkulturmediums zur produktion von il-18bp in säugerzellen | |
| WO2014168157A1 (ja) | 肝幹前駆様細胞の培養方法及びその培養物 | |
| JP2014508527A5 (enExample) | ||
| JP2010166901A5 (enExample) | ||
| JP2008289486A5 (enExample) |