HK1222887A1 - 重編程分化細胞和從重編程的細胞產生動物和胚胎幹細胞的高效方法 - Google Patents
重編程分化細胞和從重編程的細胞產生動物和胚胎幹細胞的高效方法Info
- Publication number
- HK1222887A1 HK1222887A1 HK16111146.2A HK16111146A HK1222887A1 HK 1222887 A1 HK1222887 A1 HK 1222887A1 HK 16111146 A HK16111146 A HK 16111146A HK 1222887 A1 HK1222887 A1 HK 1222887A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cells
- embryonic stem
- highly efficient
- efficient methods
- reprogrammed
- Prior art date
Links
- 210000004027 cell Anatomy 0.000 title 2
- 241001465754 Metazoa Species 0.000 title 1
- 210000001671 embryonic stem cell Anatomy 0.000 title 1
- 230000008672 reprogramming Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/027—New breeds of vertebrates
- A01K67/0273—Cloned animals
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/027—New breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0604—Whole embryos; Culture medium therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0657—Cardiomyocytes; Heart cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0393—Animal model comprising a reporter system for screening tests
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/02—Coculture with; Conditioned medium produced by embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2517/00—Cells related to new breeds of animals
- C12N2517/04—Cells produced using nuclear transfer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US90297007P | 2007-02-23 | 2007-02-23 | |
US91854307P | 2007-03-16 | 2007-03-16 | |
US99377207P | 2007-09-14 | 2007-09-14 | |
US943207P | 2007-12-28 | 2007-12-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1222887A1 true HK1222887A1 (zh) | 2017-07-14 |
Family
ID=39710674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16111146.2A HK1222887A1 (zh) | 2007-02-23 | 2016-09-22 | 重編程分化細胞和從重編程的細胞產生動物和胚胎幹細胞的高效方法 |
Country Status (10)
Country | Link |
---|---|
US (2) | US8796021B2 (zh) |
EP (3) | EP2121902A4 (zh) |
JP (4) | JP2010518857A (zh) |
KR (1) | KR20100014504A (zh) |
CN (2) | CN105441385A (zh) |
AU (1) | AU2008218998A1 (zh) |
CA (1) | CA2679109C (zh) |
HK (1) | HK1222887A1 (zh) |
IL (1) | IL200522A (zh) |
WO (1) | WO2008103462A2 (zh) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2005304978A1 (en) | 2004-11-04 | 2006-05-18 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells |
US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
EP2302034B1 (en) | 2005-08-03 | 2020-10-14 | Astellas Institute for Regenerative Medicine | Improved methods of reprogramming animal somatic cells |
EP2121902A4 (en) | 2007-02-23 | 2010-12-22 | Advanced Cell Tech Inc | HIGHLY EFFICIENT METHODS OF RENEWING DIFFERENTIATED CELLS AND GENERATING ANIMALS AND EMBRYONIC STEM CELLS FROM NEWLY PROGRAMMED CELLS |
US9102920B2 (en) | 2008-05-06 | 2015-08-11 | Agency For Science, Technology And Research | Method of effecting de-differentiation of a cell |
CN101798569B (zh) * | 2009-02-09 | 2012-11-21 | 北京瑞途之星科技有限公司 | 以卵裂后的发育胚胎替代卵母细胞的治疗性克隆新方法 |
JP5909482B2 (ja) * | 2010-03-31 | 2016-04-26 | ザ スクリプス リサーチ インスティテュート | 細胞の再プログラム |
CN101921808B (zh) * | 2010-08-18 | 2012-05-30 | 东北农业大学 | 一种提高猪体细胞核移植效率的方法 |
US20120184035A1 (en) * | 2011-01-13 | 2012-07-19 | Sadhana Agarwal | Methods and Compositions For Reprogramming Cells |
WO2012174086A1 (en) * | 2011-06-14 | 2012-12-20 | J. R. Simplot Company | A method for identifying a mammal receptive to embryo transfer |
WO2013010045A1 (en) | 2011-07-12 | 2013-01-17 | Biotime Inc. | Novel methods and formulations for orthopedic cell therapy |
CN102321571A (zh) * | 2011-09-21 | 2012-01-18 | 王跃嗣 | 从分化细胞制备自体造血干细胞的方法 |
ES2690212T3 (es) | 2011-11-30 | 2018-11-19 | Astellas Institute For Regenerative Medicine | Células estromales mesenquimales y usos relacionados con las mismas |
US9428732B2 (en) * | 2011-12-05 | 2016-08-30 | Primorigen Biosciences, Inc. | Compositions and methods for differentiating pluripotent stem cells into primitive blood cells and uses thereof |
WO2013106753A1 (en) * | 2012-01-13 | 2013-07-18 | The Board Of Trustees Of The Leland Stanford Junior University | Mechanical biomarkers for oocyte and embryo viability |
CN102608323A (zh) * | 2012-03-26 | 2012-07-25 | 西北农林科技大学 | 一种基于哺乳动物囊胚的分子免疫检测的胚胎质量分析方法 |
US9896699B2 (en) | 2013-03-15 | 2018-02-20 | New York Stem Cell Foundation, Inc. | Somatic cell nuclear transfer methods |
CA2908443A1 (en) * | 2013-04-16 | 2014-10-23 | Koninklijke Nederlandse Akademie Van Wetenschappen | Blastoid, cell line based artificial blastocyst |
JP2016073207A (ja) * | 2014-10-02 | 2016-05-12 | 株式会社リプロセル | 細胞凍結保存方法、細胞解凍方法、及び細胞 |
CN107889507B (zh) | 2015-03-23 | 2021-11-26 | 安斯泰来再生医药协会 | 改进的人视网膜色素(rpe)细胞和感光祖细胞的效能测定 |
KR102447145B1 (ko) | 2016-03-31 | 2022-09-23 | 샌바이오, 인크. | 줄기 세포 배양 및 치료를 위한 배지, 방법, 세포 및 분비 인자 |
EP3555262A4 (en) * | 2016-11-07 | 2020-05-13 | K2 Research Holdings, LLC | PRODUCTION AND THERAPEUTIC USES OF EPINUL PLURIPOTENT CELLS AND DIFFERENTIATED CELLS DERIVED THEREFROM |
CN107099553A (zh) * | 2017-06-19 | 2017-08-29 | 内蒙古大学 | 一种小鼠体细胞核移植方法 |
WO2019060735A1 (en) | 2017-09-21 | 2019-03-28 | EMULATE, Inc. | PHYSIOLOGY AND PATHOPHYSIOLOGY OF HUMAN INTESTINES: INTESTIN-ON-CHIP |
CN108624621B (zh) * | 2018-01-17 | 2019-04-12 | 中国科学院上海生命科学研究院 | 非人灵长类的体细胞克隆动物的制备方法 |
CN110819585B (zh) * | 2018-08-09 | 2022-12-06 | 山东大学 | 含有igf2的胚胎体外培育方法和培养基 |
TWI715874B (zh) * | 2018-09-27 | 2021-01-11 | 台灣粒線體應用技術股份有限公司 | 無血清培養液以及使用此無血清培養液分離和放大培養幹細胞方法 |
EP3870188A1 (en) * | 2018-10-23 | 2021-09-01 | The Board of Trustees of the Leland Stanford Junior University | Prevention and treatment of teratoma formation in stem cell-based thereapies using alternating electric fields |
WO2022272042A2 (en) * | 2021-06-25 | 2022-12-29 | The J. David Gladstone Institutes, A Testamentary Trust Established Under The Will Of J. David Gladstone | Primordial germ cells |
CN113925878B (zh) * | 2021-10-20 | 2024-03-08 | 上海交通大学医学院附属仁济医院 | 一种细胞外囊泡在治疗神经损伤性勃起功能障碍中的应用 |
CN114128668A (zh) * | 2021-11-24 | 2022-03-04 | 华中农业大学 | 一种提高水牛夏季同期发情-定时输精效果的处理方法 |
Family Cites Families (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4441972A (en) | 1983-04-08 | 1984-04-10 | D.E.P. Systems, Inc. | Apparatus for electrofusion of biological particles |
US4664097A (en) | 1984-05-09 | 1987-05-12 | The Wistar Institute Of Anatomy & Biology | Nuclear transplantation in the mammalian embryo by microsurgery and cell fusion |
US4578168A (en) | 1984-07-27 | 1986-03-25 | Biotronics | Apparatus for fusing live cells with electric fields |
US4994384A (en) | 1986-12-31 | 1991-02-19 | W. R. Grace & Co.-Conn. | Multiplying bovine embryos |
US5057420A (en) | 1987-06-05 | 1991-10-15 | Granada Biosciences, Inc. | Bovine nuclear transplantation |
US5213979A (en) | 1987-12-30 | 1993-05-25 | W. R. Grace & Co.-Conn. | In vitro culture of bovine embryos |
BR8907666A (pt) | 1988-09-21 | 1991-07-30 | Cambridge Animal Biotech | Derivacao de linhas de celulas embrionarias pluripotenciais de animais domesticos |
US4944384A (en) | 1989-01-30 | 1990-07-31 | Hay & Forage Industries | Trash discharge apparatus for crop transferring conveyor mechanism |
JP3375957B2 (ja) | 1990-07-09 | 2003-02-10 | アムラド・コーポレイション・リミテッド | 白血病抑制因子を用いる胚の増強移植、増殖及び維持 |
US5096822A (en) | 1990-07-26 | 1992-03-17 | W. R. Grace & Co.- Conn. | Bovine embryo medium |
JP3104995B2 (ja) | 1991-01-31 | 2000-10-30 | ワーナー−ランバート・コンパニー | 抗炎症剤として有用な4,6−ジ−第三ブチル−5−ヒドロキシ−1,3−ピリミジンの置換されたヘテロアリール類似体 |
US5173158A (en) | 1991-07-22 | 1992-12-22 | Schmukler Robert E | Apparatus and methods for electroporation and electrofusion |
US5496720A (en) | 1993-02-10 | 1996-03-05 | Susko-Parrish; Joan L. | Parthenogenic oocyte activation |
GB9308271D0 (en) | 1993-04-21 | 1993-06-02 | Univ Edinburgh | Method of isolating and/or enriching and/or selectively propagating pluripotential animal cells and animals for use in said method |
US5523226A (en) | 1993-05-14 | 1996-06-04 | Biotechnology Research And Development Corp. | Transgenic swine compositions and methods |
WO1995016770A1 (en) | 1993-12-17 | 1995-06-22 | Abs Global, Inc. | Ungulate preblastocyst derived embryonic stem cells and use thereof to produce cloned transgenic and chimeric ungulates |
EP1149898A2 (en) | 1993-12-23 | 2001-10-31 | Infigen, Inc. | Embryonic stem cells as nuclear donors and nuclear transfer techniques to produce chimeric and transgenic animals |
US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
US7696404B2 (en) * | 1996-08-19 | 2010-04-13 | Advanced Cell Technology, Inc. | Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions |
US5945577A (en) | 1997-01-10 | 1999-08-31 | University Of Massachusetts As Represented By Its Amherst Campus | Cloning using donor nuclei from proliferating somatic cells |
US20090092588A1 (en) * | 1997-01-10 | 2009-04-09 | University Of Massachusetts As Represented By Its Amherst Campus | Cloned ungulate embryos and animals, use of cells, tissues and organs thereof for transplantation therapies including parkinson's disease |
US6011197A (en) * | 1997-03-06 | 2000-01-04 | Infigen, Inc. | Method of cloning bovines using reprogrammed non-embryonic bovine cells |
EP0973871A1 (en) | 1997-03-06 | 2000-01-26 | Infigen, Inc. | Method of cloning animals |
US6667176B1 (en) * | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
US6372494B1 (en) | 1999-05-14 | 2002-04-16 | Advanced Tissue Sciences, Inc. | Methods of making conditioned cell culture medium compositions |
US20040199935A1 (en) | 1999-06-30 | 2004-10-07 | Chapman Karen B. | Cytoplasmic transfer to de-differentiate recipient cells |
US7621606B2 (en) | 2001-08-27 | 2009-11-24 | Advanced Cell Technology, Inc. | Trans-differentiation and re-differentiation of somatic cells and production of cells for cell therapies |
NZ516236A (en) | 1999-06-30 | 2004-12-24 | Advanced Cell Tech Inc | Altering life span of a recipient cell by transferring cell cytoplasm from a donor cell for use in gene therapy and cloning |
MXPA02003732A (es) * | 1999-10-14 | 2004-09-10 | Univ Massachusetts | Preparacion y seleccion de celulas donadoras para transplante nuclear. |
EP1226239A4 (en) * | 1999-10-15 | 2003-02-12 | Advanced Cell Tech Inc | Process for the preparation of differentiated progenitor cells and embryonic stem cells with line defects |
EP1240318A4 (en) | 1999-12-20 | 2004-12-08 | Univ Massachusetts | EMBRYONAL OR STEM CELL-LIKE CELLS PRODUCED BY CROSS-SPECIES, NUCLEAR TRANSPLANTATION |
US20030213008A1 (en) * | 1999-12-20 | 2003-11-13 | Perry Anthony C.F. | Method to produce cloned embryos and adults from cultured cells |
EP1248517A2 (en) * | 2000-01-07 | 2002-10-16 | Oregon Health and Science University | Clonal propagation of primate offspring by embryo splitting |
DE10108412B4 (de) * | 2001-02-21 | 2006-03-09 | Cevec Pharmaceuticals Gmbh | Pigmentepithelzelle des Auges, ihre Herstellung und Verwendung in der Therapie einer Augen- oder Nervenerkrankung |
IL160507A0 (en) | 2001-08-24 | 2004-07-25 | Advanced Cell Tech Inc | Screening assays for identifying differentiation-inducing agents and production of differentiated cells for cell therapy |
JP2003067271A (ja) * | 2001-08-27 | 2003-03-07 | Hitachi Ltd | 統合管理システム |
US20030044976A1 (en) * | 2001-08-27 | 2003-03-06 | Advanced Cell Technology | De-differentiation and re-differentiation of somatic cells and production of cells for cell therapies |
JP2005510232A (ja) * | 2001-11-26 | 2005-04-21 | アドバンスド セル テクノロジー、インク. | 再プログラムされたヒト体細胞核ならびに自系および同系なヒト幹細胞の製造および使用方法 |
WO2003057836A2 (en) | 2001-12-27 | 2003-07-17 | Advanced Cell Technology, Inc. | Embryonic or stem-like cell lines produced by cross species nuclear transplantation and methods for enhancing embryonic development by genetic alteration of donor cells or by tissue culture conditions |
US7247477B2 (en) | 2002-04-16 | 2007-07-24 | Technion Research & Development Foundation Ltd. | Methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells |
WO2003100011A2 (en) | 2002-05-23 | 2003-12-04 | Advanced Cell Technology, Inc. | Generation of histocompatible tissues using nuclear transplantation |
US7612250B2 (en) | 2002-07-29 | 2009-11-03 | Trustees Of Tufts College | Nuclear transfer embryo formation method |
CN1708582A (zh) | 2002-10-31 | 2005-12-14 | 独立行政法人理化学研究所 | 多能干细胞培养用的组合物及其使用 |
AU2003296480A1 (en) * | 2002-12-10 | 2004-06-30 | The Wistar Institute | Method for programmed differentiation of stem cells |
JP4613069B2 (ja) | 2002-12-16 | 2011-01-12 | テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド | 支持細胞非含有、異種非含有のヒト胚性幹細胞の調製方法およびこれらを使用して調製された幹細胞培養物 |
US20040229350A1 (en) * | 2003-05-12 | 2004-11-18 | Nikolai Strelchenko | Morula derived embryonic stem cells |
US20050118713A1 (en) * | 2003-05-12 | 2005-06-02 | Nikolai Strelchenko | Morula derived embryonic stem cells |
TW200521236A (en) * | 2003-12-22 | 2005-07-01 | Animal Technology Inst Taiwan | Method for generating non-human mammalian chimeric embryo |
EP2438814A3 (en) | 2004-01-23 | 2012-10-03 | Advanced Cell Technology, Inc. | Improved modalities for the treatment of degenerative diseases of the retina |
US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
GB2441530B (en) | 2004-02-12 | 2009-09-23 | Univ Newcastle | Stem Cells |
WO2006013519A1 (en) | 2004-07-26 | 2006-02-09 | Koninklijke Philips Electronics N.V. | Method of storing data in an information carrier, system for reading such an information carrier. |
WO2006013573A2 (en) | 2004-08-06 | 2006-02-09 | Mendy Erad Ltd. | Early detection of harmful agents: method, system and kit |
US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
AU2005304978A1 (en) | 2004-11-04 | 2006-05-18 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells |
EP2302034B1 (en) | 2005-08-03 | 2020-10-14 | Astellas Institute for Regenerative Medicine | Improved methods of reprogramming animal somatic cells |
US20090271335A1 (en) * | 2005-10-20 | 2009-10-29 | Advanced Cell Technology, Inc. | Totipotent, Nearly Totipotent or Pluripotent Mammalian Cells Homozygous or Hemizygous for One or More Histocompatibility Antigent Genes |
US20080070303A1 (en) | 2005-11-21 | 2008-03-20 | West Michael D | Methods to accelerate the isolation of novel cell strains from pluripotent stem cells and cells obtained thereby |
WO2007058671A1 (en) | 2005-11-21 | 2007-05-24 | West Michael D | Novel uses of cells with prenatal patterns of gene expression |
EP2029724A4 (en) | 2006-05-03 | 2010-03-24 | Advanced Cell Tech Inc | DERIVATION FROM EMBRYONAL STEM CELLS AND EMBRYO-DERIVED CELLS |
CN100465268C (zh) * | 2006-05-17 | 2009-03-04 | 北京大学 | 人胚胎干细胞的培养方法及其专用培养基 |
US20070298496A1 (en) * | 2006-06-23 | 2007-12-27 | Hung-Chih Kuo | Method of deriving pluripotent stem cells from a single blastomere |
EP2121902A4 (en) | 2007-02-23 | 2010-12-22 | Advanced Cell Tech Inc | HIGHLY EFFICIENT METHODS OF RENEWING DIFFERENTIATED CELLS AND GENERATING ANIMALS AND EMBRYONIC STEM CELLS FROM NEWLY PROGRAMMED CELLS |
-
2008
- 2008-02-22 EP EP08725969A patent/EP2121902A4/en not_active Withdrawn
- 2008-02-22 CN CN201510660811.9A patent/CN105441385A/zh active Pending
- 2008-02-22 AU AU2008218998A patent/AU2008218998A1/en not_active Abandoned
- 2008-02-22 KR KR1020097019691A patent/KR20100014504A/ko not_active Application Discontinuation
- 2008-02-22 CN CN200880013190A patent/CN101679942A/zh active Pending
- 2008-02-22 US US12/528,212 patent/US8796021B2/en active Active
- 2008-02-22 EP EP16183074.0A patent/EP3190178A1/en not_active Withdrawn
- 2008-02-22 CA CA2679109A patent/CA2679109C/en active Active
- 2008-02-22 JP JP2009550931A patent/JP2010518857A/ja active Pending
- 2008-02-22 EP EP15164113.1A patent/EP2982744A1/en not_active Withdrawn
- 2008-02-22 WO PCT/US2008/002380 patent/WO2008103462A2/en active Application Filing
-
2009
- 2009-08-20 IL IL200522A patent/IL200522A/en active IP Right Grant
-
2013
- 2013-05-07 JP JP2013097811A patent/JP5955809B2/ja active Active
-
2014
- 2014-07-23 US US14/338,596 patent/US10584313B2/en active Active
-
2016
- 2016-06-15 JP JP2016119245A patent/JP6423386B2/ja active Active
- 2016-09-22 HK HK16111146.2A patent/HK1222887A1/zh unknown
-
2018
- 2018-10-18 JP JP2018196337A patent/JP2019004912A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
KR20100014504A (ko) | 2010-02-10 |
US20100240132A1 (en) | 2010-09-23 |
IL200522A0 (en) | 2011-08-01 |
EP2121902A2 (en) | 2009-11-25 |
CN101679942A (zh) | 2010-03-24 |
JP2019004912A (ja) | 2019-01-17 |
US20150175960A1 (en) | 2015-06-25 |
IL200522A (en) | 2016-06-30 |
JP2016163593A (ja) | 2016-09-08 |
AU2008218998A1 (en) | 2008-08-28 |
CN105441385A (zh) | 2016-03-30 |
JP6423386B2 (ja) | 2018-11-14 |
CA2679109A1 (en) | 2008-08-28 |
WO2008103462A2 (en) | 2008-08-28 |
WO2008103462A3 (en) | 2008-11-27 |
EP3190178A1 (en) | 2017-07-12 |
JP5955809B2 (ja) | 2016-07-20 |
US8796021B2 (en) | 2014-08-05 |
EP2121902A4 (en) | 2010-12-22 |
US10584313B2 (en) | 2020-03-10 |
JP2013146280A (ja) | 2013-08-01 |
CA2679109C (en) | 2016-07-19 |
EP2982744A1 (en) | 2016-02-10 |
JP2010518857A (ja) | 2010-06-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1222887A1 (zh) | 重編程分化細胞和從重編程的細胞產生動物和胚胎幹細胞的高效方法 | |
IL272848B (en) | Methods for reprogramming cells and their use | |
EP1997281A4 (en) | METHOD AND SYSTEM FOR RECOGNIZING DESIRABLE E-MAIL | |
IL212433A0 (en) | Pluripotent stem cells obtained by non-viral reprogramming | |
GB0716313D0 (en) | Methods for embryonic stem cell culture | |
EP2446928A4 (en) | METHOD FOR KILLING TUMOR CELLS SELECTIVELY AND APPARATUS FOR THE METHOD | |
EP2155859A4 (en) | FORMULATIONS AND METHODS FOR CULTIVATING EMBRYONIC STEM CELLS | |
SI2240572T1 (sl) | Uporaba RNA za reprogramiranje somatskih celic | |
EP2096169A4 (en) | NUCLEAR-NEUPROGRAMMIERUNGSVERFAHREN | |
EP2283117A4 (en) | METHODS FOR THE PURIFICATION OF ENDODERMIC AND PANCREATIC ENDODERM CELLS FROM HUMAN EMBRYONIC STEM CELLS | |
IL201384A0 (en) | Patient - specific stem cell lines derived from human parthenogenetic blastocysts | |
EP1874191A4 (en) | REAL-TIME REPRESENTATION CONTROLLED ELECTROPORATION | |
IL193883A0 (en) | Human embryonic stem cell methods and podxl expression | |
IL207036A0 (en) | Stem cell aggregates and methods for making and using | |
ZA200908680B (en) | Crushing plant and method for controlling the same | |
EP2133119A4 (en) | METHOD FOR CONTROLLING THE HAIR GROWTH AND DEVICE FOR THE PROCEDURE | |
EP2133120A4 (en) | METHOD FOR CONTROLLING HAIR GROWTH, AND APPARATUS ASSOCIATED WITH THE METHOD | |
EP2021464A4 (en) | METHOD FOR CULTURING HUMAN EMBRYONIC STEM CELLS | |
EP2173310A4 (en) | METHODS FOR PROMOTING HAIR GROWTH | |
ZA200908474B (en) | Crushing plant and method for controlling the same | |
GB0812789D0 (en) | Materials and methods for cell growth | |
EP2513297A4 (en) | MATERIALS AND METHODS FOR THE PRODUCTION OF PLURIPOTENT STEM CELLS | |
IL178480A0 (en) | Methods for generating neuronal cells from human embryonic stem cells and uses thereof | |
IL201346A0 (en) | Newcompositions and methods for cell killing | |
EP2446020A4 (en) | RE-PROGRAMMING OF DENTAL STEM CELLS |