MX2015013118A - Composiciones y métodos para la producción y administración de ácido ribonucleico. - Google Patents

Composiciones y métodos para la producción y administración de ácido ribonucleico.

Info

Publication number
MX2015013118A
MX2015013118A MX2015013118A MX2015013118A MX2015013118A MX 2015013118 A MX2015013118 A MX 2015013118A MX 2015013118 A MX2015013118 A MX 2015013118A MX 2015013118 A MX2015013118 A MX 2015013118A MX 2015013118 A MX2015013118 A MX 2015013118A
Authority
MX
Mexico
Prior art keywords
methods
compositions
dsrna
rna
delivery
Prior art date
Application number
MX2015013118A
Other languages
English (en)
Other versions
MX358744B (es
Inventor
James A Baum
Artem Evdokimov
Lisa Marie Weaver
Farhad Moshiri
Allen T Christian
Haitao Zhang
Original Assignee
Monsanto Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US201361793506P priority Critical
Application filed by Monsanto Technology Llc filed Critical Monsanto Technology Llc
Priority to PCT/US2014/026036 priority patent/WO2014151581A1/en
Publication of MX2015013118A publication Critical patent/MX2015013118A/es
Publication of MX358744B publication Critical patent/MX358744B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/10Animals; Substances produced thereby or obtained therefrom
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H3/00Processes for modifying phenotypes, e.g. symbiosis with bacteria
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/72Expression systems using regulatory sequences derived from the lac-operon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22Ribonucleases RNAses, DNAses

Abstract

Se proporcionan composiciones y métodos para producir y administrar eficazmente ARN de doble cadena (ARNdc); se describen construcciones de vectores útiles para la expresión de ARNdc in vitro e in vivo; también se describen sistemas de expresión celular para la producción eficaz y rentable de ARNdc en células vivas y métodos y composiciones para proporcionar el ARNdc expresado a organismos diana; objetivo; las composiciones y métodos descritos se pueden usar para producir moléculas de ARN para analisis u otros usos, y para amplificar secuencias de ARN para su análisis.
MX2015013118A 2013-03-15 2014-03-13 Composiciones y métodos para la producción y administración de ácido ribonucleico. MX358744B (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US201361793506P true 2013-03-15 2013-03-15
PCT/US2014/026036 WO2014151581A1 (en) 2013-03-15 2014-03-13 Compositions and methods for the improved production and delivery of rna by efficient transcription termination

Publications (2)

Publication Number Publication Date
MX2015013118A true MX2015013118A (es) 2016-02-09
MX358744B MX358744B (es) 2018-08-31

Family

ID=50928237

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015013118A MX358744B (es) 2013-03-15 2014-03-13 Composiciones y métodos para la producción y administración de ácido ribonucleico.

Country Status (14)

Country Link
US (6) US9814243B2 (es)
EP (2) EP3434777A1 (es)
JP (2) JP6522579B2 (es)
KR (1) KR20150131310A (es)
CN (2) CN105164265B (es)
AR (1) AR095462A1 (es)
AU (1) AU2014233711B2 (es)
BR (1) BR112015023424A2 (es)
CA (1) CA2905961A1 (es)
ES (1) ES2691803T3 (es)
MX (1) MX358744B (es)
UA (1) UA120349C2 (es)
WO (1) WO2014151581A1 (es)
ZA (1) ZA201506682B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012022570A2 (pt) 2010-03-08 2015-10-06 Monsato Technology Llc moléculas de polinucleotídeo para regulação de gene em plantas.
CA2809284A1 (en) 2010-08-31 2012-03-08 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
US10240161B2 (en) 2012-05-24 2019-03-26 A.B. Seeds Ltd. Compositions and methods for silencing gene expression
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
BR112015015975A2 (pt) 2013-01-01 2018-11-06 A B Seeds Ltd moléculas de dsrna isoladas e métodos de uso das mesmas para silenciamento das moléculas alvo de interesse.
CA2905027A1 (en) 2013-03-13 2014-10-09 Monsanto Technology Llc Methods and compositions for weed control
CN105263329A (zh) 2013-03-13 2016-01-20 孟山都技术公司 用于杂草控制的方法和组合物
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
ES2691803T3 (es) * 2013-03-15 2018-11-28 Monsanto Technology Llc Composiciones y procedimientos para la producción y administración de ARN
EP3608412A3 (en) 2013-07-19 2020-04-08 Monsanto Technology LLC Compositions and methods for controlling leptinotarsa
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
EP3030671B1 (en) 2013-08-05 2018-10-03 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
BR112016009963A2 (pt) 2013-11-04 2017-12-05 Beeologics Inc composições e métodos para controlar artrópodes parasitas e infestações por praga
CN105980399A (zh) 2013-12-10 2016-09-28 比欧洛吉科斯公司 用于瓦螨和蜂中的病毒控制的组合物和方法
UA121462C2 (uk) 2014-01-15 2020-06-10 Монсанто Текнолоджі Елелсі Спосіб та композиція для боротьби із бур'янами з використанням полінуклеотидів epsps
EP3174982A4 (en) 2014-07-29 2018-06-20 Monsanto Technology LLC Compositions and methods for controlling insect pests
US10655136B2 (en) 2015-06-03 2020-05-19 Monsanto Technology Llc Methods and compositions for introducing nucleic acids into plants
CN105219796A (zh) * 2015-09-29 2016-01-06 生工生物工程(上海)股份有限公司 一种转录终止子及其在基因克隆中的应用
BR112018068144A2 (pt) * 2016-03-15 2019-02-12 Apse Inc métodos e composições para maior produção de rna de fita dupla
BR112018070506A2 (pt) 2016-04-06 2019-01-29 Greenlight Biosciences Inc produção isenta de células de ácido ribonucleico
AU2018205503A1 (en) 2017-01-06 2019-07-25 Greenlight Biosciences, Inc. Cell-free production of sugars
WO2018134386A1 (en) 2017-01-23 2018-07-26 Novozymes A/S Host cells and methods for producing double-stranded rna
EP3601583A1 (en) * 2017-03-28 2020-02-05 Ajinomoto Co., Inc. Method for producing rna
US20200149048A1 (en) * 2017-05-22 2020-05-14 Pebble Labs Usa Inc. Transbiotic Regulation of Bacterial Gene Expression
WO2019163827A1 (ja) * 2018-02-20 2019-08-29 味の素株式会社 Rnaサイレンシングを誘導する方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101422167A (zh) * 2004-04-09 2009-05-06 孟山都技术有限公司 用于在植物中控制昆虫侵袭的组合物和方法
EP2439279B1 (en) * 2005-09-16 2016-11-09 Monsanto Technology LLC Methods for genetic control of insect infestations in plants and compositions thereof
PT2295584E (pt) * 2005-09-16 2015-09-22 Devgen Nv Métodos com base em plantas transgénicas para infestações em plantas utilizando arn de interferência
BR112012022570A2 (pt) * 2010-03-08 2015-10-06 Monsato Technology Llc moléculas de polinucleotídeo para regulação de gene em plantas.
WO2012015938A2 (en) * 2010-07-27 2012-02-02 The Johns Hopkins University Obligate heterodimer variants of foki cleavage domain
WO2012048385A1 (en) * 2010-10-15 2012-04-19 The University Of Queensland Small viral rna molecules and uses thereof
EP2530159A1 (en) * 2011-06-03 2012-12-05 Sandoz Ag Transcription terminator sequences
WO2012170433A1 (en) 2011-06-08 2012-12-13 Sutro Biopharma, Inc. Multiple rna polymerase terminator cassettes for efficient transcription of discrete rna templates
ES2691803T3 (es) * 2013-03-15 2018-11-28 Monsanto Technology Llc Composiciones y procedimientos para la producción y administración de ARN

Also Published As

Publication number Publication date
US10070652B2 (en) 2018-09-11
US20190380348A1 (en) 2019-12-19
EP2970990B1 (en) 2018-07-18
CN105164265B (zh) 2019-05-10
CN105164265A (zh) 2015-12-16
US20140271559A1 (en) 2014-09-18
US20180092364A1 (en) 2018-04-05
MX358744B (es) 2018-08-31
ZA201506682B (en) 2018-11-28
US9814243B2 (en) 2017-11-14
ES2691803T3 (es) 2018-11-28
WO2014151581A9 (en) 2016-01-21
CA2905961A1 (en) 2014-09-25
KR20150131310A (ko) 2015-11-24
US20170035056A1 (en) 2017-02-09
US10757947B2 (en) 2020-09-01
UA120349C2 (uk) 2019-11-25
US20190000089A1 (en) 2019-01-03
US10334858B2 (en) 2019-07-02
AU2014233711A9 (en) 2016-06-16
WO2014151581A1 (en) 2014-09-25
JP6522579B2 (ja) 2019-05-29
AR095462A1 (es) 2015-10-21
EP3434777A1 (en) 2019-01-30
EP2970990A1 (en) 2016-01-20
BR112015023424A2 (pt) 2017-11-28
US20160145630A1 (en) 2016-05-26
US9445603B2 (en) 2016-09-20
JP2016517274A (ja) 2016-06-16
JP2019150036A (ja) 2019-09-12
CN110229815A (zh) 2019-09-13
AU2014233711A1 (en) 2015-10-01
AU2014233711B2 (en) 2020-05-28

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