MX2015013118A - Composiciones y métodos para la producción y administración de ácido ribonucleico. - Google Patents

Composiciones y métodos para la producción y administración de ácido ribonucleico.

Info

Publication number
MX2015013118A
MX2015013118A MX2015013118A MX2015013118A MX2015013118A MX 2015013118 A MX2015013118 A MX 2015013118A MX 2015013118 A MX2015013118 A MX 2015013118A MX 2015013118 A MX2015013118 A MX 2015013118A MX 2015013118 A MX2015013118 A MX 2015013118A
Authority
MX
Mexico
Prior art keywords
methods
compositions
dsrna
rna
delivery
Prior art date
Application number
MX2015013118A
Other languages
English (en)
Other versions
MX358744B (es
Inventor
James A Baum
Artem Evdokimov
Lisa Marie Weaver
Farhad Moshiri
Allen T Christian
Haitao Zhang
Original Assignee
Monsanto Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Technology Llc filed Critical Monsanto Technology Llc
Publication of MX2015013118A publication Critical patent/MX2015013118A/es
Publication of MX358744B publication Critical patent/MX358744B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/60—Isolated nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H3/00—Processes for modifying phenotypes, e.g. symbiosis with bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/50—Physical structure
    • C12N2310/53—Physical structure partially self-complementary or closed
    • C12N2310/531—Stem-loop; Hairpin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Abstract

Se proporcionan composiciones y métodos para producir y administrar eficazmente ARN de doble cadena (ARNdc); se describen construcciones de vectores útiles para la expresión de ARNdc in vitro e in vivo; también se describen sistemas de expresión celular para la producción eficaz y rentable de ARNdc en células vivas y métodos y composiciones para proporcionar el ARNdc expresado a organismos diana; objetivo; las composiciones y métodos descritos se pueden usar para producir moléculas de ARN para analisis u otros usos, y para amplificar secuencias de ARN para su análisis.
MX2015013118A 2013-03-15 2014-03-13 Composiciones y métodos para la producción y administración de ácido ribonucleico. MX358744B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361793506P 2013-03-15 2013-03-15
PCT/US2014/026036 WO2014151581A1 (en) 2013-03-15 2014-03-13 Compositions and methods for the improved production and delivery of rna by efficient transcription termination

Publications (2)

Publication Number Publication Date
MX2015013118A true MX2015013118A (es) 2016-02-09
MX358744B MX358744B (es) 2018-08-31

Family

ID=50928237

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015013118A MX358744B (es) 2013-03-15 2014-03-13 Composiciones y métodos para la producción y administración de ácido ribonucleico.
MX2018010529A MX2018010529A (es) 2013-03-15 2015-09-15 Composiciones y metodos para la produccion y administracion de acido ribonucleico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2018010529A MX2018010529A (es) 2013-03-15 2015-09-15 Composiciones y metodos para la produccion y administracion de acido ribonucleico.

Country Status (14)

Country Link
US (7) US9445603B2 (es)
EP (2) EP3434777B1 (es)
JP (2) JP6522579B2 (es)
KR (3) KR20230066486A (es)
CN (2) CN105164265B (es)
AR (1) AR095462A1 (es)
AU (1) AU2014233711B2 (es)
BR (1) BR112015023424A2 (es)
CA (1) CA2905961C (es)
ES (2) ES2691803T3 (es)
MX (2) MX358744B (es)
UA (1) UA120349C2 (es)
WO (1) WO2014151581A1 (es)
ZA (1) ZA201506682B (es)

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JP6843065B2 (ja) 2015-03-30 2021-03-17 グリーンライト バイオサイエンシーズ インコーポレーテッドＧｒｅｅｎｌｉｇｈｔ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． リボ核酸の無細胞生産
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Also Published As

Publication number Publication date
JP6522579B2 (ja) 2019-05-29
AR095462A1 (es) 2015-10-21
US20140271559A1 (en) 2014-09-18
AU2014233711A9 (en) 2016-06-16
CN105164265B (zh) 2019-05-10
CN110229815B (zh) 2024-02-20
US20230232838A1 (en) 2023-07-27
US20190380348A1 (en) 2019-12-19
CN105164265A (zh) 2015-12-16
MX358744B (es) 2018-08-31
US9814243B2 (en) 2017-11-14
EP2970990A1 (en) 2016-01-20
EP3434777A1 (en) 2019-01-30
WO2014151581A1 (en) 2014-09-25
KR102530901B1 (ko) 2023-05-11
BR112015023424A2 (pt) 2017-11-28
US20160145630A1 (en) 2016-05-26
ES2691803T3 (es) 2018-11-28
US20170035056A1 (en) 2017-02-09
US9445603B2 (en) 2016-09-20
US20190000089A1 (en) 2019-01-03
MX2018010529A (es) 2022-01-25
UA120349C2 (uk) 2019-11-25
WO2014151581A9 (en) 2015-12-03
US10334858B2 (en) 2019-07-02
US11647753B2 (en) 2023-05-16
EP3434777B1 (en) 2020-09-23
US20180092364A1 (en) 2018-04-05
JP2019150036A (ja) 2019-09-12
JP2016517274A (ja) 2016-06-16
CA2905961A1 (en) 2014-09-25
KR20230066486A (ko) 2023-05-15
AU2014233711B2 (en) 2020-05-28
KR20150131310A (ko) 2015-11-24
US10757947B2 (en) 2020-09-01
KR20210116681A (ko) 2021-09-27
CA2905961C (en) 2023-04-25
ES2837575T3 (es) 2021-06-30
AU2014233711A1 (en) 2015-10-01
JP6935450B2 (ja) 2021-09-15
US10070652B2 (en) 2018-09-11
ZA201506682B (en) 2018-11-28
CN110229815A (zh) 2019-09-13
EP2970990B1 (en) 2018-07-18

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