DE266710C
(es)
|
|
|
|
|
US3883511A
(en)
|
1974-03-07 |
1975-05-13 |
Rit Rech Ind Therapeut |
New 6-aminopenicillanic acid derivative
|
USRE30985E
(en)
|
1978-01-01 |
1982-06-29 |
|
Serum-free cell culture media
|
FR2413974A1
(fr)
|
1978-01-06 |
1979-08-03 |
David Bernard |
Sechoir pour feuilles imprimees par serigraphie
|
US4419446A
(en)
|
1980-12-31 |
1983-12-06 |
The United States Of America As Represented By The Department Of Health And Human Services |
Recombinant DNA process utilizing a papilloma virus DNA as a vector
|
NZ201705A
(en)
|
1981-08-31 |
1986-03-14 |
Genentech Inc |
Recombinant dna method for production of hepatitis b surface antigen in yeast
|
US4601978A
(en)
|
1982-11-24 |
1986-07-22 |
The Regents Of The University Of California |
Mammalian metallothionein promoter system
|
US4560655A
(en)
|
1982-12-16 |
1985-12-24 |
Immunex Corporation |
Serum-free cell culture medium and process for making same
|
US4657866A
(en)
|
1982-12-21 |
1987-04-14 |
Sudhir Kumar |
Serum-free, synthetic, completely chemically defined tissue culture media
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
DD266710A3
(de)
|
1983-06-06 |
1989-04-12 |
Ve Forschungszentrum Biotechnologie |
Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase
|
US4767704A
(en)
|
1983-10-07 |
1988-08-30 |
Columbia University In The City Of New York |
Protein-free culture medium
|
US4965199A
(en)
|
1984-04-20 |
1990-10-23 |
Genentech, Inc. |
Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
|
US4879231A
(en)
|
1984-10-30 |
1989-11-07 |
Phillips Petroleum Company |
Transformation of yeasts of the genus pichia
|
GB8516415D0
(en)
|
1985-06-28 |
1985-07-31 |
Celltech Ltd |
Culture of animal cells
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
US4927762A
(en)
|
1986-04-01 |
1990-05-22 |
Cell Enterprises, Inc. |
Cell culture medium with antioxidant
|
GB8610600D0
(en)
|
1986-04-30 |
1986-06-04 |
Novo Industri As |
Transformation of trichoderma
|
IL87737A
(en)
|
1987-09-11 |
1993-08-18 |
Genentech Inc |
Method for culturing polypeptide factor dependent vertebrate recombinant cells
|
CA1338518C
(en)
|
1987-09-23 |
1996-08-13 |
Joyce M. Zarling |
Antibody heteroconjugates for the killing of hiv-infected cells
|
DE68925971T2
(de)
|
1988-09-23 |
1996-09-05 |
Cetus Oncology Corp |
Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
KR0184860B1
(ko)
|
1988-11-11 |
1999-04-01 |
메디칼 리써어치 카운실 |
단일영역 리간드와 이를 포함하는 수용체 및 이들의 제조방법과 이용(법)
|
FR2646437B1
(fr)
|
1989-04-28 |
1991-08-30 |
Transgene Sa |
Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant
|
EP0402226A1
(en)
|
1989-06-06 |
1990-12-12 |
Institut National De La Recherche Agronomique |
Transformation vectors for yeast yarrowia
|
DE69029036T2
(de)
|
1989-06-29 |
1997-05-22 |
Medarex Inc |
Bispezifische reagenzien für die aids-therapie
|
US5959177A
(en)
|
1989-10-27 |
1999-09-28 |
The Scripps Research Institute |
Transgenic plants expressing assembled secretory antibodies
|
DE69120146T2
(de)
|
1990-01-12 |
1996-12-12 |
Cell Genesys Inc |
Erzeugung xenogener antikörper
|
JP3230091B2
(ja)
|
1990-06-25 |
2001-11-19 |
ウェルファイド株式会社 |
ヒト血清アルブミンの着色抑制方法
|
ES2246502T3
(es)
|
1990-08-29 |
2006-02-16 |
Genpharm International, Inc. |
Animales no humanos transgenicos capaces de producir anticuerpos heterologos.
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5122469A
(en)
|
1990-10-03 |
1992-06-16 |
Genentech, Inc. |
Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
|
EP0571390B1
(en)
*
|
1990-11-23 |
2000-03-08 |
Peptech Limited |
The delay, prevention and/or reversal of cell senescence
|
ES2113940T3
(es)
|
1990-12-03 |
1998-05-16 |
Genentech Inc |
Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas.
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
EP0586505A1
(en)
|
1991-05-14 |
1994-03-16 |
Repligen Corporation |
Heteroconjugate antibodies for treatment of hiv infection
|
US7018809B1
(en)
|
1991-09-19 |
2006-03-28 |
Genentech, Inc. |
Expression of functional antibody fragments
|
DK0605522T3
(da)
|
1991-09-23 |
2000-01-17 |
Medical Res Council |
Fremgangsmåde til fremstilling af humaniserede antistoffer
|
US5587458A
(en)
|
1991-10-07 |
1996-12-24 |
Aronex Pharmaceuticals, Inc. |
Anti-erbB-2 antibodies, combinations thereof, and therapeutic and diagnostic uses thereof
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
US5667988A
(en)
|
1992-01-27 |
1997-09-16 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
AU675929B2
(en)
|
1992-02-06 |
1997-02-27 |
Curis, Inc. |
Biosynthetic binding protein for cancer marker
|
WO1993018143A1
(en)
|
1992-03-04 |
1993-09-16 |
Synaptic Pharmaceutical Corporation |
Dna encoding taurine and gaba transporters and uses thereof
|
JPH07102147B2
(ja)
*
|
1992-03-16 |
1995-11-08 |
株式会社ミドリ十字 |
ヒト血清アルブミンの着色抑制方法
|
ATE149570T1
(de)
|
1992-08-17 |
1997-03-15 |
Genentech Inc |
Bispezifische immunoadhesine
|
CA2149329C
(en)
|
1992-11-13 |
2008-07-15 |
Darrell R. Anderson |
Therapeutic application of chimeric and radiolabeled antibodies to human b lymphocyte restricted differentiation antigen for treatment of b cell lymphoma
|
US5856179A
(en)
|
1994-03-10 |
1999-01-05 |
Genentech, Inc. |
Polypeptide production in animal cell culture
|
US5789199A
(en)
|
1994-11-03 |
1998-08-04 |
Genentech, Inc. |
Process for bacterial production of polypeptides
|
US5840523A
(en)
|
1995-03-01 |
1998-11-24 |
Genetech, Inc. |
Methods and compositions for secretion of heterologous polypeptides
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
US5641870A
(en)
|
1995-04-20 |
1997-06-24 |
Genentech, Inc. |
Low pH hydrophobic interaction chromatography for antibody purification
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
ES2304786T3
(es)
|
1995-04-27 |
2008-10-16 |
Amgen Fremont Inc. |
Anticuerpos anti-il-8 humanos, derivados a partir de xenoratones inmunizados.
|
EP0823941A4
(en)
|
1995-04-28 |
2001-09-19 |
Abgenix Inc |
HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES
|
US6267958B1
(en)
|
1995-07-27 |
2001-07-31 |
Genentech, Inc. |
Protein formulation
|
DK1500329T3
(da)
|
1996-12-03 |
2012-07-09 |
Amgen Fremont Inc |
Humane antistoffer, der specifikt binder TNF-alfa
|
US20080318254A9
(en)
|
1997-03-10 |
2008-12-25 |
The Regents Of The University Of California |
PSCA antibodies and hybridomas producing them
|
US20020012991A1
(en)
*
|
1997-04-07 |
2002-01-31 |
Florence Chua Nee Ho Kit Fong |
Cell culture media for enhanced protein production
|
US20020173629A1
(en)
|
1997-05-05 |
2002-11-21 |
Aya Jakobovits |
Human monoclonal antibodies to epidermal growth factor receptor
|
US6171586B1
(en)
|
1997-06-13 |
2001-01-09 |
Genentech, Inc. |
Antibody formulation
|
WO1998059035A2
(en)
*
|
1997-06-25 |
1998-12-30 |
The Goverment Of The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services, National Institutes Of Health |
Serum-free cell growth medium
|
US6040498A
(en)
|
1998-08-11 |
2000-03-21 |
North Caroline State University |
Genetically engineered duckweed
|
US6610833B1
(en)
|
1997-11-24 |
2003-08-26 |
The Institute For Human Genetics And Biochemistry |
Monoclonal human natural antibodies
|
DE60039596D1
(de)
|
1999-03-30 |
2008-09-04 |
Japan Tobacco Inc |
Verfahren zur herstellung von monoklonalen antikörpern
|
US7125978B1
(en)
|
1999-10-04 |
2006-10-24 |
Medicago Inc. |
Promoter for regulating expression of foreign genes
|
AU782626B2
(en)
|
1999-10-04 |
2005-08-18 |
Medicago Inc. |
Method for regulating transcription of foreign genes
|
RU2192884C2
(ru)
*
|
2000-11-09 |
2002-11-20 |
Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН |
Вакцина для стимуляции противоопухолевого иммунитета
|
US7311905B2
(en)
*
|
2002-02-13 |
2007-12-25 |
Anthrogenesis Corporation |
Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
|
WO2002092017A2
(en)
|
2001-05-16 |
2002-11-21 |
Albert Einstein College Of Medicine Of Yeshiva University |
Human antipneumococcal antibodies from non-human animals
|
AU2002316230A1
(en)
|
2001-06-13 |
2002-12-23 |
Genentech, Inc. |
Methods of culturing animal cells and polypeptide production in animal cells
|
JP4359503B2
(ja)
|
2001-08-23 |
2009-11-04 |
ゲンマブ エー/エス |
インターロイキン15(il−15)に特異的なヒト抗体
|
US7371922B2
(en)
*
|
2002-07-31 |
2008-05-13 |
The Board Of Trustees Of The University Of Illinois |
Nuclear transfer with porcine embryonic stem cells
|
DE60332957D1
(de)
*
|
2002-12-16 |
2010-07-22 |
Genentech Inc |
Immunoglobulinvarianten und deren verwendungen
|
EP1590364B1
(en)
|
2002-12-16 |
2011-10-05 |
Genmab A/S |
Human monoclonal antibodies against interleukin 8 (il-8)
|
CA2513308A1
(en)
|
2003-01-17 |
2004-08-05 |
Josef Michl |
Pancreatic cancer associated antigen, antibody thereto, and diagnostic and treatment methods
|
WO2004069172A2
(en)
*
|
2003-01-30 |
2004-08-19 |
The Government of the United States of America as represented by the Department of Veterans Affairs |
Multilineage-inducible cells and uses thereof
|
AU2004270103B2
(en)
|
2003-05-21 |
2012-02-23 |
E. R. Squibb & Sons, L.L.C. |
Human monoclonal antibodies against Bacillusanthracis protective antigen
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
WO2006047380A2
(en)
|
2004-10-22 |
2006-05-04 |
Amgen, Inc. |
Method and media for single cell serum-fee culture of cho cells
|
WO2006050050A2
(en)
|
2004-10-29 |
2006-05-11 |
Centocor, Inc. |
Chemically defined media compositions
|
US8207303B2
(en)
*
|
2005-02-18 |
2012-06-26 |
Medarex, Inc. |
Monoclonal antibodies against CD30 lacking in fucosyl residues
|
JP2008536524A
(ja)
*
|
2005-04-21 |
2008-09-11 |
グレン エー. ゴールドスタイン, |
不妊に関連する酸化ストレス治療のためのn−アセチルシステインアミド(nacアミド)
|
KR20070122497A
(ko)
*
|
2005-04-22 |
2007-12-31 |
제넨테크, 인크. |
Cd20 항체로 치매 또는 알츠하이머병을 치료하는 방법
|
MX2007014148A
(es)
|
2005-05-19 |
2008-01-11 |
Amgen Inc |
Composiciones y metodos para incrementar la estabilidad de anticuerpos.
|
PE20070796A1
(es)
|
2005-10-24 |
2007-08-15 |
Wyeth Corp |
Metodo de produccion proteica utilizando compuestos anti-senescencia
|
CA2654716A1
(en)
|
2006-06-09 |
2007-12-21 |
Anthrogenesis Corporation |
Placental niche and use thereof to culture stem cells
|
TW200902708A
(en)
*
|
2007-04-23 |
2009-01-16 |
Wyeth Corp |
Methods of protein production using anti-senescence compounds
|
ES2591284T3
(es)
|
2007-08-07 |
2016-11-25 |
Chugai Seiyaku Kabushiki Kaisha |
Método para la producción de proteínas heterogéneas
|
CN101815786A
(zh)
|
2007-10-12 |
2010-08-25 |
弗·哈夫曼-拉罗切有限公司 |
来自多个核酸的蛋白质表达
|
CN101418330B
(zh)
|
2008-06-20 |
2012-01-04 |
华东理工大学 |
适于nso细胞大规模培养及抗体生产的无蛋白培养基
|
CN102224239A
(zh)
*
|
2008-09-26 |
2011-10-19 |
先灵公司 |
高效价抗体生产
|
CN101603026B
(zh)
*
|
2009-06-19 |
2011-01-19 |
华东理工大学 |
适于动物细胞产品生产的无动物来源低蛋白培养基
|
CA2765220A1
(en)
|
2009-07-14 |
2011-01-20 |
Biogen Idec Ma Inc. |
Methods for inhibiting yellow color and peroxide formation in a composition
|
HUE048980T2
(hu)
|
2009-08-11 |
2020-08-28 |
Hoffmann La Roche |
Fehérjék elõállítása glutaminmentes sejttenyésztõ táptalajban
|
LT2563906T
(lt)
|
2010-04-26 |
2018-02-26 |
Novartis Ag |
Cho ląstelių kultivavimo būdas
|
KR20130118899A
(ko)
*
|
2010-11-05 |
2013-10-30 |
애브비 인코포레이티드 |
세포배양에서의 화학적으로 규명된 배지의 개발을 위한 효율적이고 효과적인 보충물 스크리닝
|
CN102093978A
(zh)
|
2010-12-17 |
2011-06-15 |
上海市农业科学院 |
猪早期胚胎发育前期培养液及后期培养液
|
US20120171161A1
(en)
*
|
2010-12-30 |
2012-07-05 |
Sascha Abramson |
Compositions comprising placental stem cells and platelet rich plasma, and methods of use thereof
|
US20130281355A1
(en)
|
2012-04-24 |
2013-10-24 |
Genentech, Inc. |
Cell culture compositions and methods for polypeptide production
|
US20150267237A1
(en)
*
|
2012-04-24 |
2015-09-24 |
Genentech, Inc. |
Cell culture compositions and methods for polypeptide production
|
WO2014029772A1
(en)
|
2012-08-20 |
2014-02-27 |
Schreder |
Method of and system for isolating led luminaires from electrical surges
|
WO2014145098A1
(en)
|
2013-03-15 |
2014-09-18 |
Genentech, Inc. |
Cell culture compositions with antioxidants and methods for polypeptide production
|