JP2010533001A5 - - Google Patents
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- Publication number
- JP2010533001A5 JP2010533001A5 JP2010516334A JP2010516334A JP2010533001A5 JP 2010533001 A5 JP2010533001 A5 JP 2010533001A5 JP 2010516334 A JP2010516334 A JP 2010516334A JP 2010516334 A JP2010516334 A JP 2010516334A JP 2010533001 A5 JP2010533001 A5 JP 2010533001A5
- Authority
- JP
- Japan
- Prior art keywords
- vlp
- plant
- composition
- influenza virus
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 101710154606 Hemagglutinin Proteins 0.000 claims 6
- 101710093908 Outer capsid protein VP4 Proteins 0.000 claims 6
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 claims 6
- 101710176177 Protein A56 Proteins 0.000 claims 6
- 239000000185 hemagglutinin Substances 0.000 claims 5
- 238000000034 method Methods 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 241000712461 unidentified influenza virus Species 0.000 claims 4
- 230000001939 inductive effect Effects 0.000 claims 3
- 206010022000 influenza Diseases 0.000 claims 3
- 239000002773 nucleotide Substances 0.000 claims 3
- 125000003729 nucleotide group Chemical group 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 2
- 230000036039 immunity Effects 0.000 claims 2
- 239000002245 particle Substances 0.000 claims 2
- 230000009385 viral infection Effects 0.000 claims 2
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US95941407P | 2007-07-13 | 2007-07-13 | |
| US60/959,414 | 2007-07-13 | ||
| US99060307P | 2007-11-27 | 2007-11-27 | |
| US60/990,603 | 2007-11-27 | ||
| US1327207P | 2007-12-12 | 2007-12-12 | |
| US61/013,272 | 2007-12-12 | ||
| CA2,615,372 | 2008-01-21 | ||
| CA002615372A CA2615372A1 (en) | 2007-07-13 | 2008-01-21 | Influenza virus-like particles (vlps) comprising hemagglutinin |
| US2277508P | 2008-01-22 | 2008-01-22 | |
| US61/022,775 | 2008-01-22 | ||
| PCT/CA2008/001281 WO2009009876A1 (en) | 2007-07-13 | 2008-07-11 | Influenza virus-like particles (vlps) comprising hemagglutinin produced within a plant |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010533001A JP2010533001A (ja) | 2010-10-21 |
| JP2010533001A5 true JP2010533001A5 (enExample) | 2013-08-29 |
| JP5624465B2 JP5624465B2 (ja) | 2014-11-12 |
Family
ID=40255124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010516334A Active JP5624465B2 (ja) | 2007-07-13 | 2008-07-11 | 植物内で生成されるヘマグルチニンを含むインフルエンザウイルス様粒子（ｖｌｐ） |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US20100239610A1 (enExample) |
| EP (1) | EP2173886B1 (enExample) |
| JP (1) | JP5624465B2 (enExample) |
| KR (1) | KR101541330B1 (enExample) |
| CN (1) | CN101883856B (enExample) |
| AU (1) | AU2008278222B2 (enExample) |
| CA (2) | CA2615372A1 (enExample) |
| CR (1) | CR11209A (enExample) |
| DK (1) | DK2173886T3 (enExample) |
| EA (1) | EA018206B1 (enExample) |
| ES (1) | ES2428384T3 (enExample) |
| MX (1) | MX2010000525A (enExample) |
| MY (1) | MY155236A (enExample) |
| NZ (1) | NZ582360A (enExample) |
| PL (1) | PL2173886T3 (enExample) |
| PT (1) | PT2173886E (enExample) |
| SI (1) | SI2173886T1 (enExample) |
| TN (1) | TN2009000557A1 (enExample) |
| WO (1) | WO2009009876A1 (enExample) |
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| NZ587108A (en) | 2007-11-27 | 2013-04-26 | Medicago Inc | Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin |
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| MX370690B (es) | 2008-07-18 | 2019-12-19 | Medicago Inc | Epitopo de inmunizacion de nuevo virus de la influenza. |
| AU2015202195B2 (en) * | 2008-07-18 | 2017-10-12 | Medicago Inc. | New influenza virus immunizing epitope |
| CN104263729B (zh) | 2009-03-16 | 2020-09-15 | 帝斯曼知识产权资产有限公司 | 在网粘菌门微生物中产生蛋白质 |
| WO2010117786A1 (en) | 2009-03-30 | 2010-10-14 | Mount Sinai School Of Medicine Of New York University | Influenza virus vaccines and uses thereof |
| EP2417153B1 (en) * | 2009-04-09 | 2014-11-05 | Alfa Biogene International B.V. | Filtration of a liquid comprising a plant stress protein |
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| EP2448596B1 (en) | 2009-07-02 | 2016-01-06 | Massachusetts Institute of Technology | Compositions and methods for diagnosing and/or treating influenza infection |
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| CA2813078A1 (en) | 2010-10-04 | 2012-04-12 | Massachusetts Institute Of Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
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| WO2013043729A1 (en) | 2011-09-20 | 2013-03-28 | Mount Sinai School Of Medicine | Influenza virus vaccines and uses thereof |
| US11155581B2 (en) * | 2011-09-30 | 2021-10-26 | Medicago Inc. | Increasing virus-like particle yield in plants |
| US11390878B2 (en) | 2011-09-30 | 2022-07-19 | Medicago Inc. | Increasing protein yield in plants |
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| BR112014018884A2 (pt) | 2012-02-07 | 2017-07-04 | Univ Pittsburgh Commonwealth Sys Higher Education | antígenos amplamente reativos computacionalmente otimizados para viroses de influenza h3n2, h2n2, e b |
| EP3305806B1 (en) | 2012-02-13 | 2020-08-26 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Computationally optimized broadly reactive antigens for human and avian h5n1 influenza |
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| MX386517B (es) * | 2012-09-05 | 2025-03-19 | Medicago Inc | Produccion de particulas similares a picornavirus en plantas. |
| EP2934581B1 (en) | 2012-12-18 | 2022-09-14 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
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| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| JP2016516415A (ja) | 2013-03-28 | 2016-06-09 | メディカゴ インコーポレイテッド | 植物におけるインフルエンザウイルス様粒子の生成 |
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| AU2015286165B2 (en) * | 2014-07-11 | 2021-03-11 | Medicago Inc. | Modifying protein production in plants |
| WO2016118937A1 (en) | 2015-01-23 | 2016-07-28 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccination regimens |
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| KR101637955B1 (ko) * | 2015-05-18 | 2016-07-08 | 한국생명공학연구원 | 범용성 인플루엔자 바이러스 백신 조성물 |
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| US11266734B2 (en) | 2016-06-15 | 2022-03-08 | Icahn School Of Medicine At Mount Sinai | Influenza virus hemagglutinin proteins and uses thereof |
| EP3606555A4 (en) | 2017-04-07 | 2021-08-04 | Icahn School of Medicine at Mount Sinai | INFLUENZA B VIRUS NEURAMINIDASE ANTIBODIES AND USES THEREOF |
| KR101964044B1 (ko) * | 2018-03-14 | 2019-04-02 | 인제대학교 산학협력단 | 재조합 아데노바이러스를 이용한 다가형 인플루엔자 생백신 플랫폼 |
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| WO2019246363A1 (en) | 2018-06-21 | 2019-12-26 | Icahn School Of Medicine At Mount Sinai | Mosaic influenza virus hemagglutinin polypeptides and uses thereof |
| CA3103849A1 (en) * | 2018-06-27 | 2020-01-02 | Medicago Inc. | Influenza virus hemagglutinin mutants |
| CN112384615A (zh) * | 2018-07-04 | 2021-02-19 | 普罗拜奥根股份公司 | 用于纯化包膜病毒的方法 |
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| WO2010077712A1 (en) | 2008-12-09 | 2010-07-08 | Novavax, Inc. | Bovine respiratory syncytial virus virus-like particle (vlps) |
| EP3228627A1 (en) * | 2009-06-24 | 2017-10-11 | Medicago Inc. | Chimeric influenza virus- like particles comprising hemagglutinin |
| WO2011011390A1 (en) | 2009-07-20 | 2011-01-27 | Novavax, Inc. | Purified recombinant influenza virus ha proteins |
| PH12012500565B1 (en) | 2009-09-22 | 2018-01-12 | Medicago Inc | Method of preparing plant-derived proteins |
| CA2789945A1 (en) | 2010-02-18 | 2011-08-25 | Technovax, Inc. | Universal virus-like particle (vlp) influenza vaccines |
| US20130295609A1 (en) | 2010-11-04 | 2013-11-07 | Medicago Inc. | Plant expression system |
| HRP20171213T1 (hr) | 2010-11-05 | 2017-10-20 | Novavax, Inc. | Glikoproteinske čestice nalik virusu (vlp) bjesnoće |
| TWI526539B (zh) | 2010-12-22 | 2016-03-21 | 苜蓿股份有限公司 | 植物中生產類病毒顆粒(vlp)的方法及以該方法生產之vlp |
-
2008
- 2008-01-21 CA CA002615372A patent/CA2615372A1/en not_active Abandoned
- 2008-07-11 MX MX2010000525A patent/MX2010000525A/es active IP Right Grant
- 2008-07-11 PL PL08783201T patent/PL2173886T3/pl unknown
- 2008-07-11 MY MYPI2010000142A patent/MY155236A/en unknown
- 2008-07-11 EP EP08783201.0A patent/EP2173886B1/en active Active
- 2008-07-11 SI SI200831024T patent/SI2173886T1/sl unknown
- 2008-07-11 CN CN2008801070729A patent/CN101883856B/zh active Active
- 2008-07-11 NZ NZ582360A patent/NZ582360A/en unknown
- 2008-07-11 PT PT87832010T patent/PT2173886E/pt unknown
- 2008-07-11 CA CA2693956A patent/CA2693956C/en active Active
- 2008-07-11 AU AU2008278222A patent/AU2008278222B2/en active Active
- 2008-07-11 ES ES08783201T patent/ES2428384T3/es active Active
- 2008-07-11 US US12/669,033 patent/US20100239610A1/en not_active Abandoned
- 2008-07-11 WO PCT/CA2008/001281 patent/WO2009009876A1/en not_active Ceased
- 2008-07-11 DK DK08783201.0T patent/DK2173886T3/da active
- 2008-07-11 JP JP2010516334A patent/JP5624465B2/ja active Active
- 2008-07-11 EA EA201000195A patent/EA018206B1/ru not_active IP Right Cessation
- 2008-07-11 KR KR1020107002538A patent/KR101541330B1/ko active Active
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2009
- 2009-07-02 US US13/003,570 patent/US9492528B2/en active Active
- 2009-12-31 TN TNP2009000557A patent/TN2009000557A1/fr unknown
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2010
- 2010-01-11 CR CR11209A patent/CR11209A/es not_active Application Discontinuation
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2013
- 2013-01-04 US US13/734,886 patent/US9452210B2/en active Active
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2022
- 2022-07-27 US US17/815,503 patent/US20230044454A1/en not_active Abandoned
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