PE20121685A1 - Antigeno ndv recombinante y usos del mismo - Google Patents

Antigeno ndv recombinante y usos del mismo

Info

Publication number
PE20121685A1
PE20121685A1 PE2012000888A PE2012000888A PE20121685A1 PE 20121685 A1 PE20121685 A1 PE 20121685A1 PE 2012000888 A PE2012000888 A PE 2012000888A PE 2012000888 A PE2012000888 A PE 2012000888A PE 20121685 A1 PE20121685 A1 PE 20121685A1
Authority
PE
Peru
Prior art keywords
ndv
antigen
same
polypeptide
variety
Prior art date
Application number
PE2012000888A
Other languages
English (en)
Inventor
Xuan Guo
Karolyn Marie Troupe
Bradley Feilmeier Jr
Joyce Anita Pritchard
Julio Sergio Cruz-Coy
Original Assignee
Merial Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd filed Critical Merial Ltd
Publication of PE20121685A1 publication Critical patent/PE20121685A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/517—Plant cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18111—Avulavirus, e.g. Newcastle disease virus
    • C12N2760/18134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Abstract

SE REFIERE A UNA COMPOSICION QUE COMPRENDE UN POLIPEPTIDO O ANTIGENO HN (HEMAGLUTININA-NEURAMINIDASA) DEL NDV (VIRUS DE LA ENFERMEDAD DE NEWCASTLE) Y UN TRANSPORTADOR, EXCIPIENTE, VEHICULO O ADYUVANTE FARMACEUTICAMENTE ACEPTABLE O APTO PARA USO VETERINARIO TAL COMO UNA EMULSION DE AGUA EN ACEITE O DE ACEITE EN AGUA. DICHO POLIPEPTIDO O ANTIGENO HN NDV TIENE AL MENOS UN 80% DE IDENTIDAD DE SECUENCIA CON LA SECUENCIA SEQ ID Nº: 3, 5, 7, 9, 15, 17 O 20, ADEMAS COMPRENDE UN FRAGMENTO INMUNOGENICO QUE COMPRENDE UNA REGION DEL EPITOPE LINEAL HN NDV. REFERIDO ADEMAS A UN METODO DE PRODUCCION. DICHA COMPOSICION GENERA UNA RESPUESTA INMUNOGENICA EN UN ANIMAL
PE2012000888A 2009-12-28 2010-12-28 Antigeno ndv recombinante y usos del mismo PE20121685A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29029709P 2009-12-28 2009-12-28

Publications (1)

Publication Number Publication Date
PE20121685A1 true PE20121685A1 (es) 2012-12-28

Family

ID=44189168

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2012000888A PE20121685A1 (es) 2009-12-28 2010-12-28 Antigeno ndv recombinante y usos del mismo

Country Status (11)

Country Link
US (1) US10633667B2 (es)
EP (2) EP2519258B1 (es)
JP (1) JP5933451B2 (es)
KR (1) KR20120101572A (es)
CN (1) CN103260643A (es)
AR (2) AR079767A1 (es)
CA (1) CA2785653C (es)
DO (1) DOP2012000187A (es)
MX (1) MX351643B (es)
PE (1) PE20121685A1 (es)
WO (1) WO2011090708A2 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4130273A1 (en) * 2009-12-28 2023-02-08 Sanofi Vaccine Technologies, S.A.S. Production of heterologous polypeptides in microalgae, microalgal extracellular bodies, compositions, and methods of making and uses thereof
EA030095B1 (ru) * 2009-12-28 2018-06-29 ДиЭсЭм АйПи АССЕТС Б.В. Получение белка гемагглютинин-нейраминидазы в микроводорослях
WO2012153160A1 (es) * 2011-05-07 2012-11-15 Laboratorio Avi-Mex, S.A. De C.V. Vacuna recombinante contra prrs en vector viral
US9358283B2 (en) 2011-10-28 2016-06-07 The Regents Of The University Of California Diatom-based vaccines
WO2013164095A1 (en) * 2012-05-02 2013-11-07 Algenics Production of secreted therapeutic antibodies in microalgae
EP2660324A1 (en) * 2012-05-02 2013-11-06 Algenics Production of secreted therapeutic antibodies in microalgae
EP2660323A1 (en) * 2012-05-02 2013-11-06 Algenics Production of secreted therapeutic antibodies in phaeodactylum tricornutum microalgae
EP2671950A1 (de) * 2012-06-06 2013-12-11 Philipps-Universität Marburg Expression und Sekretion von rekombinanten, vollständig assemblierten Proteinkomplexen durch Mikroalgen
CN105695491B (zh) * 2014-05-09 2020-01-10 中国农业科学院生物技术研究所 鸡新城疫糖蛋白病毒抗原的制备方法及其产品
CN105567715B (zh) * 2014-10-17 2021-06-29 丰益(上海)生物技术研发中心有限公司 裂殖壶菌α-微管蛋白相关序列及其应用
AU2015342997B2 (en) * 2014-11-05 2021-11-18 Research Institute At Nationwide Children's Hospital Methods and materials for producing recombinant viruses in eukaryotic microalgae
US10196616B2 (en) * 2017-02-15 2019-02-05 The United States Of America, As Represented By The Secretary Of Agriculture Altered avian virus for in-ovo inoculation and methods of use thereof
CN107099513B (zh) * 2017-06-22 2020-07-14 北京邦卓生物科技有限公司 一种共表达ndv hn和ibdv vp2基因的hvt的构建及其应用
CN113652406B (zh) * 2021-09-01 2023-05-02 青岛易邦生物工程有限公司 一种鸡传染性喉气管炎重组病毒株及其应用

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Also Published As

Publication number Publication date
CA2785653A1 (en) 2011-07-28
EP2519258B1 (en) 2017-07-26
DOP2012000187A (es) 2012-12-15
EP3213766A1 (en) 2017-09-06
AR122325A2 (es) 2022-08-31
US10633667B2 (en) 2020-04-28
JP2013515747A (ja) 2013-05-09
AR079767A1 (es) 2012-02-15
JP5933451B2 (ja) 2016-06-08
CA2785653C (en) 2018-05-01
EP2519258A2 (en) 2012-11-07
MX351643B (es) 2017-10-23
WO2011090708A2 (en) 2011-07-28
MX2012007545A (es) 2012-11-12
WO2011090708A3 (en) 2011-12-15
US20110162115A1 (en) 2011-06-30
KR20120101572A (ko) 2012-09-13
CN103260643A (zh) 2013-08-21

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