JP2016516415A5 - - Google Patents
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- Publication number
- JP2016516415A5 JP2016516415A5 JP2016504431A JP2016504431A JP2016516415A5 JP 2016516415 A5 JP2016516415 A5 JP 2016516415A5 JP 2016504431 A JP2016504431 A JP 2016504431A JP 2016504431 A JP2016504431 A JP 2016504431A JP 2016516415 A5 JP2016516415 A5 JP 2016516415A5
- Authority
- JP
- Japan
- Prior art keywords
- plant
- nucleic acid
- modified
- protein
- vlp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361806227P | 2013-03-28 | 2013-03-28 | |
| US61/806,227 | 2013-03-28 | ||
| US201461925852P | 2014-01-10 | 2014-01-10 | |
| US61/925,852 | 2014-01-10 | ||
| US201461971274P | 2014-03-27 | 2014-03-27 | |
| US61/971,274 | 2014-03-27 | ||
| PCT/CA2014/050326 WO2014153674A1 (en) | 2013-03-28 | 2014-03-28 | Influenza virus-like particle production in plants |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019067570A Division JP7065803B2 (ja) | 2013-03-28 | 2019-03-29 | 植物におけるインフルエンザウイルス様粒子の生成 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016516415A JP2016516415A (ja) | 2016-06-09 |
| JP2016516415A5 true JP2016516415A5 (enExample) | 2017-03-09 |
Family
ID=51622327
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016504431A Pending JP2016516415A (ja) | 2013-03-28 | 2014-03-28 | 植物におけるインフルエンザウイルス様粒子の生成 |
| JP2019067570A Active JP7065803B2 (ja) | 2013-03-28 | 2019-03-29 | 植物におけるインフルエンザウイルス様粒子の生成 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019067570A Active JP7065803B2 (ja) | 2013-03-28 | 2019-03-29 | 植物におけるインフルエンザウイルス様粒子の生成 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US10358652B2 (enExample) |
| EP (2) | EP3626827A1 (enExample) |
| JP (2) | JP2016516415A (enExample) |
| KR (1) | KR102199018B1 (enExample) |
| CN (2) | CN105247059B (enExample) |
| AU (1) | AU2014245779B2 (enExample) |
| ES (1) | ES2803508T3 (enExample) |
| IL (2) | IL241692B2 (enExample) |
| MX (1) | MX376138B (enExample) |
| PH (1) | PH12015502217A1 (enExample) |
| RU (2) | RU2742607C1 (enExample) |
| SG (1) | SG11201507928QA (enExample) |
| WO (1) | WO2014153674A1 (enExample) |
| ZA (1) | ZA201508327B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI700368B (zh) | 2011-09-30 | 2020-08-01 | 苜蓿股份有限公司 | 增加植物類病毒顆粒產率 |
| US11390878B2 (en) | 2011-09-30 | 2022-07-19 | Medicago Inc. | Increasing protein yield in plants |
| JP2016516415A (ja) * | 2013-03-28 | 2016-06-09 | メディカゴ インコーポレイテッド | 植物におけるインフルエンザウイルス様粒子の生成 |
| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| BR112016015875A2 (pt) | 2014-01-10 | 2017-09-19 | Medicago Inc | Elementos intensificadores de cpmv |
| AU2015234595B2 (en) | 2014-03-27 | 2021-03-25 | Medicago Inc. | Modified CPMV enhancer elements |
| DK3134131T3 (en) | 2014-04-23 | 2022-02-07 | Modernatx Inc | Nucleic acid vaccines |
| FR3054547B1 (fr) | 2016-07-29 | 2020-06-05 | Angany Inc. | Particules pseudo-virales et leurs utilisations |
| GB201614485D0 (en) | 2016-08-25 | 2016-10-12 | Univ Oxford Innovation Ltd | Immunogenic composition |
| CN106822887A (zh) * | 2017-01-26 | 2017-06-13 | 中国科学院微生物研究所 | 一种流感病毒四价亚单位疫苗及其应用 |
| JP7423875B6 (ja) | 2018-03-14 | 2024-03-15 | メディカゴ インコーポレイテッド | 植物発現エンハンサ |
| AU2019295495B2 (en) | 2018-06-27 | 2025-05-22 | Aramis Biotechnologies Inc. | Influenza virus hemagglutinin mutants |
| BR112021017899A2 (pt) * | 2019-03-14 | 2021-12-21 | Medicago Inc | Intensificador de expressão vegetal endógeno |
| CN113249399B (zh) * | 2021-05-27 | 2022-08-02 | 长沙诺合松生物科技合伙企业(有限合伙) | pAM基因及其植物表达载体和应用 |
| US20250325649A1 (en) * | 2021-12-31 | 2025-10-23 | Mynvax Private Limited | Polypeptide fragments, immunogenic composition against influenza virus, and implementations thereof |
| WO2025102071A1 (en) * | 2023-11-09 | 2025-05-15 | The General Hospital Corporation | Hemagglutinin polypeptides and uses thereof |
| WO2026027730A1 (en) * | 2024-07-31 | 2026-02-05 | Sanofi | Modified h5 influenza hemagglutinin polypeptides and nucleic acids and uses thereof |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5232833A (en) | 1988-09-14 | 1993-08-03 | Stressgen Biotechnologies Corporation | Accumulation of heat shock proteins for evaluating biological damage due to chronic exposure of an organism to sublethal levels of pollutants |
| US6392121B1 (en) | 1998-10-07 | 2002-05-21 | Boyce Thompson Institute For Plant Research | Gemini virus vectors for gene expression in plants |
| US20020169306A1 (en) * | 1999-05-18 | 2002-11-14 | Kaio Kitazato | Envelope gene-deficient paramyxovirus vector |
| AU5076301A (en) | 1999-12-06 | 2001-07-09 | Board Of Trustees Of The University Of Illinois, The | High affinity tcr proteins and methods |
| DE10109354A1 (de) | 2001-02-27 | 2002-09-05 | Icon Genetics Ag | Rekombinante virale Schaltersysteme |
| US20030180756A1 (en) * | 2002-03-21 | 2003-09-25 | Yang Shi | Compositions and methods for suppressing eukaryotic gene expression |
| US8784335B2 (en) | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
| AU2004235813B2 (en) | 2003-05-05 | 2010-07-29 | Boyce Thompson Institute For Plant Research | Vectors and cells for preparing immunoprotective compositions derived from transgenic plants |
| NZ542933A (en) * | 2003-05-05 | 2009-08-28 | Dow Agrosciences Llc | Stable immunoprophylactic and therapeutic compositions derived from transgenic plant cells and methods for production |
| US8080255B2 (en) | 2003-07-11 | 2011-12-20 | Novavax Inc. | Functional influenza virus like particles (VLPs) |
| ES2662118T3 (es) | 2005-04-29 | 2018-04-05 | University Of Cape Town | Expresión de proteínas virales en las plantas |
| RU2483751C2 (ru) | 2005-10-18 | 2013-06-10 | Новавакс, Инк. | ФУНКЦИОНАЛЬНЫЕ ВИРУСОПОДОБНЫЕ ЧАСТИЦЫ ГРИППА (VLPs) |
| CN101484466A (zh) | 2006-02-16 | 2009-07-15 | 美国国有健康与人类服务部(马里兰州) | 针对流感病毒的抗病毒剂和疫苗 |
| ES2555544T3 (es) * | 2006-03-07 | 2016-01-04 | Vaxinnate Corporation | Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas |
| US7618815B2 (en) | 2006-03-08 | 2009-11-17 | University Of Kentucky Research Foundation | Viral vectors useful in soybean and methods of use |
| EP2029755A1 (en) | 2006-05-22 | 2009-03-04 | Plant Bioscience Limited | Bipartite system, method and composition for the constitutive and inducible expression of high levels of foreign proteins in plants |
| JP2010500034A (ja) | 2006-08-09 | 2010-01-07 | メッドイミューン バクシーンズ，インコーポレイティド | インフルエンザ赤血球凝集素変異体およびノイラミニダーゼ変異体 |
| WO2008148104A1 (en) | 2007-05-25 | 2008-12-04 | Novavax, Inc. | Novel vlps derived from cells that do not express a viral matrix or core protein |
| CN104962579A (zh) | 2007-06-15 | 2015-10-07 | 麦迪卡格公司 | 修饰植物中的糖蛋白产生 |
| CA2615372A1 (en) * | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| NZ587108A (en) * | 2007-11-27 | 2013-04-26 | Medicago Inc | Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin |
| GB0800272D0 (en) | 2008-01-08 | 2008-02-13 | Plant Bioscience Ltd | Protein expression systems |
| SG187500A1 (en) * | 2008-01-21 | 2013-02-28 | Medicago Inc | Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin |
| DK2294202T3 (en) | 2008-07-08 | 2015-08-31 | Medicago Inc | SOLUBLE RECOMBINANT INFLUENZA ANTIGENES |
| KR101745925B1 (ko) | 2008-07-18 | 2017-06-12 | 메디카고 인코포레이티드 | 신규 인플루엔자 바이러스 면역화 에피토프 |
| CA2736796A1 (en) | 2008-08-27 | 2010-03-04 | Arizona Board Of Regents For And On Behalf Of Arizona State University | A dna replicon system for high-level rapid production of vaccines and monoclonal antibody therapeutics in plants |
| JP2012521786A (ja) * | 2009-03-30 | 2012-09-20 | モウント シナイ スクール オフ メディシネ | インフルエンザウイルスワクチン及びその使用 |
| SI2445928T1 (en) * | 2009-06-24 | 2018-05-31 | Medicago Inc. | HYPER PARTICULARS, SIMILAR VIRUSES OF GRIPE, WHICH HAVE EXPOSED HEMAGLUTININE |
| FR2947875B1 (fr) | 2009-07-10 | 2011-07-08 | Raymond A & Cie | Dispositif de fixation a elements de fixation multiples dont l'un est flottant |
| WO2011011390A1 (en) | 2009-07-20 | 2011-01-27 | Novavax, Inc. | Purified recombinant influenza virus ha proteins |
| KR20120093193A (ko) | 2009-09-04 | 2012-08-22 | 신젠타 파티서페이션즈 아게 | 식물 폴리펩티드 발현 증가를 위한 번역 향상제 요소의 적층 |
| SG178918A1 (en) * | 2009-09-22 | 2012-04-27 | Medicago Inc | Method of preparing plant-derived vlps |
| CA2789945A1 (en) | 2010-02-18 | 2011-08-25 | Technovax, Inc. | Universal virus-like particle (vlp) influenza vaccines |
| WO2012047941A2 (en) * | 2010-10-04 | 2012-04-12 | Massachusetts Institute Of Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
| ES2614527T3 (es) | 2010-11-04 | 2017-05-31 | Medicago Inc. | Sistema de expresión en plantas |
| TWI526539B (zh) | 2010-12-22 | 2016-03-21 | 苜蓿股份有限公司 | 植物中生產類病毒顆粒(vlp)的方法及以該方法生產之vlp |
| TWI620816B (zh) | 2011-03-23 | 2018-04-11 | 苜蓿股份有限公司 | 植物衍生蛋白回收方法 |
| US20140227322A1 (en) | 2011-06-13 | 2014-08-14 | Medicago Inc. | Rabies virus like particle production in plants |
| PL220281B1 (pl) | 2011-09-23 | 2015-09-30 | Inst Biochemii I Biofizyki Polskiej Akademii Nauk | Szczepionka DNA, sposób indukowania odpowiedzi immunologicznej, przeciwciała specyficznie rozpoznające białko hemaglutyniny H5 wirusa grypy i zastosowanie szczepionki DNA |
| US11390878B2 (en) * | 2011-09-30 | 2022-07-19 | Medicago Inc. | Increasing protein yield in plants |
| TWI700368B (zh) * | 2011-09-30 | 2020-08-01 | 苜蓿股份有限公司 | 增加植物類病毒顆粒產率 |
| WO2013068593A1 (en) | 2011-11-11 | 2013-05-16 | Philip Morris Products S.A. | Influenza virus -like particles (vlps) comprising hemagglutinin produced nicotiana tabacum |
| EP2876161B1 (en) | 2012-07-23 | 2018-12-05 | The Institute of Biological Resources | Vaccine |
| JP2016516415A (ja) | 2013-03-28 | 2016-06-09 | メディカゴ インコーポレイテッド | 植物におけるインフルエンザウイルス様粒子の生成 |
-
2014
- 2014-03-28 JP JP2016504431A patent/JP2016516415A/ja active Pending
- 2014-03-28 RU RU2019135043A patent/RU2742607C1/ru active
- 2014-03-28 RU RU2015146097A patent/RU2705555C2/ru active
- 2014-03-28 EP EP19206629.8A patent/EP3626827A1/en active Pending
- 2014-03-28 EP EP14773061.8A patent/EP2978848B1/en active Active
- 2014-03-28 US US14/779,423 patent/US10358652B2/en active Active
- 2014-03-28 IL IL241692A patent/IL241692B2/en unknown
- 2014-03-28 KR KR1020157030865A patent/KR102199018B1/ko active Active
- 2014-03-28 CN CN201480029001.7A patent/CN105247059B/zh active Active
- 2014-03-28 IL IL295155A patent/IL295155A/en unknown
- 2014-03-28 MX MX2015013700A patent/MX376138B/es active IP Right Grant
- 2014-03-28 SG SG11201507928QA patent/SG11201507928QA/en unknown
- 2014-03-28 ES ES14773061T patent/ES2803508T3/es active Active
- 2014-03-28 AU AU2014245779A patent/AU2014245779B2/en active Active
- 2014-03-28 WO PCT/CA2014/050326 patent/WO2014153674A1/en not_active Ceased
- 2014-03-28 CN CN202011519705.6A patent/CN112592389A/zh active Pending
-
2015
- 2015-09-23 PH PH12015502217A patent/PH12015502217A1/en unknown
- 2015-10-26 ZA ZA2015/08327A patent/ZA201508327B/en unknown
-
2019
- 2019-03-29 JP JP2019067570A patent/JP7065803B2/ja active Active
- 2019-07-19 US US16/516,802 patent/US11085049B2/en active Active
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