DK3092309T3 - Cpmv-forstærkerelementer - Google Patents
Cpmv-forstærkerelementer Download PDFInfo
- Publication number
- DK3092309T3 DK3092309T3 DK15735364.0T DK15735364T DK3092309T3 DK 3092309 T3 DK3092309 T3 DK 3092309T3 DK 15735364 T DK15735364 T DK 15735364T DK 3092309 T3 DK3092309 T3 DK 3092309T3
- Authority
- DK
- Denmark
- Prior art keywords
- cpmv
- amplifier elements
- amplifier
- elements
- cpmv amplifier
- Prior art date
Links
- 241000723655 Cowpea mosaic virus Species 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8251—Amino acid content, e.g. synthetic storage proteins, altering amino acid biosynthesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/045—Pseudoviral particles; Non infectious pseudovirions, e.g. genetically engineered
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nutrition Science (AREA)
- Botany (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Environmental Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Physiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461925852P | 2014-01-10 | 2014-01-10 | |
PCT/CA2014/050326 WO2014153674A1 (en) | 2013-03-28 | 2014-03-28 | Influenza virus-like particle production in plants |
PCT/CA2015/050009 WO2015103704A1 (en) | 2014-01-10 | 2015-01-08 | Cpmv enhancer elements |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3092309T3 true DK3092309T3 (da) | 2021-04-12 |
Family
ID=53523412
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK15735364.0T DK3092309T3 (da) | 2014-01-10 | 2015-01-08 | Cpmv-forstærkerelementer |
Country Status (12)
Country | Link |
---|---|
US (2) | US11441150B2 (da) |
EP (1) | EP3092309B1 (da) |
JP (1) | JP6518257B2 (da) |
CN (1) | CN105980561B (da) |
AU (1) | AU2015205805B2 (da) |
BR (1) | BR112016015875A2 (da) |
CA (1) | CA2936350C (da) |
DK (1) | DK3092309T3 (da) |
ES (1) | ES2864081T3 (da) |
RU (1) | RU2699982C2 (da) |
TW (1) | TWI714522B (da) |
WO (1) | WO2015103704A1 (da) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0800272D0 (en) | 2008-01-08 | 2008-02-13 | Plant Bioscience Ltd | Protein expression systems |
CN105980561B (zh) * | 2014-01-10 | 2020-06-02 | 莫迪卡戈公司 | Cpmv增强子元件 |
CN112400021A (zh) * | 2018-03-14 | 2021-02-23 | 麦迪卡格公司 | 植物表达增强子 |
AU2019434270A1 (en) | 2019-03-14 | 2021-09-30 | Aramis Biotechnologies Inc. | Endogenous plant expression enhancer |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9414118D0 (en) | 1994-07-13 | 1994-08-31 | Axis Genetics Ltd | Modified plant viruses as vectors of heterologous peptides |
US6042832A (en) | 1996-08-28 | 2000-03-28 | Thomas Jefferson University | Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid proteins |
US20010006950A1 (en) | 1998-02-11 | 2001-07-05 | Juha Punnonen | Genetic vaccine vector engineering |
US6489537B1 (en) | 1998-08-07 | 2002-12-03 | The Trustees Of The University Of Pennsylvania | Phytochelatin synthases and uses therefor |
US6287570B1 (en) | 1998-11-23 | 2001-09-11 | Patricia L. Foley | Vaccine against swine influenza virus |
US7125978B1 (en) | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
EP2336775A3 (en) | 1999-12-06 | 2013-03-20 | Board Of Trustees Of The University Of Illinois | High affinity TCR proteins and methods |
DE10109354A1 (de) | 2001-02-27 | 2002-09-05 | Icon Genetics Ag | Rekombinante virale Schaltersysteme |
BR0317765A (pt) * | 2002-12-27 | 2005-11-22 | Ct Ingenieria Genetica Biotech | Promotor artificial, fragmento de dna de um promotor artificial, cassete, vetor de dna, célula bacteriana, célula vegetal, planta transgência, descendência de plantas, e, purificação e utilização de uma proteìna recombinante |
CA2524293A1 (en) | 2003-05-05 | 2004-11-18 | Boyce Thompson Institute For Plant Research | Vectors and cells for preparing immunoprotective compositions derived from transgenic plants |
KR20060029214A (ko) | 2003-05-05 | 2006-04-05 | 다우 아그로사이언시즈 엘엘씨 | 이식 유전자 식물 세포들로부터 유래된 안정한 면역예방적및 치료적 조성물들 및 생산방법 |
WO2005018539A2 (en) | 2003-06-16 | 2005-03-03 | Medimmune Vaccines, Inc. | Influenza hemagglutinin and neuraminidase variants |
US8592197B2 (en) | 2003-07-11 | 2013-11-26 | Novavax, Inc. | Functional influenza virus-like particles (VLPs) |
US8080255B2 (en) | 2003-07-11 | 2011-12-20 | Novavax Inc. | Functional influenza virus like particles (VLPs) |
PT2374892T (pt) | 2005-04-29 | 2018-03-29 | Univ Cape Town | Expressão de proteínas virais em plantas |
CN101227920A (zh) | 2005-07-19 | 2008-07-23 | 陶氏环球技术公司 | 重组流感疫苗 |
CA2625406C (en) | 2005-10-18 | 2016-08-09 | Novavax, Inc. | Functional influenza virus like particles (vlps) |
EP1984405A4 (en) | 2006-02-13 | 2010-06-30 | Fraunhofer Usa Inc | INFLUENZA ANTIGENS, VACCINE COMPOSITIONS AND ASSOCIATED METHODS |
CN106237316A (zh) | 2006-03-07 | 2016-12-21 | 法克斯因内特公司 | 包含血细胞凝集素的组合物、制造其的方法与使用其的方法 |
US7618815B2 (en) | 2006-03-08 | 2009-11-17 | University Of Kentucky Research Foundation | Viral vectors useful in soybean and methods of use |
EP2029755A1 (en) * | 2006-05-22 | 2009-03-04 | Plant Bioscience Limited | Bipartite system, method and composition for the constitutive and inducible expression of high levels of foreign proteins in plants |
WO2008148104A1 (en) | 2007-05-25 | 2008-12-04 | Novavax, Inc. | Novel vlps derived from cells that do not express a viral matrix or core protein |
DK2610345T3 (da) * | 2007-11-27 | 2015-12-07 | Medicago Inc | Rekombinante influenzaviruslignende partikler (vlps), som er fremstillet i transgene planter, der udtrykker hæmagglutinin |
GB0724752D0 (en) * | 2007-12-19 | 2008-01-30 | Bari Mazhar A | Method for producing a thermoelectric material |
GB0800272D0 (en) * | 2008-01-08 | 2008-02-13 | Plant Bioscience Ltd | Protein expression systems |
SG187500A1 (en) * | 2008-01-21 | 2013-02-28 | Medicago Inc | Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin |
JP2012521786A (ja) | 2009-03-30 | 2012-09-20 | モウント シナイ スクール オフ メディシネ | インフルエンザウイルスワクチン及びその使用 |
WO2010148511A1 (en) * | 2009-06-24 | 2010-12-29 | Medicago, Inc. | Chimeric influenza virus-like particles comprising hemagglutinin |
EP2473616A4 (en) | 2009-09-04 | 2013-06-12 | Syngenta Participations Ag | STACKING OF TRANSLATION REINFORCING ELEMENTS FOR INCREASING POLYPEPTIDE EXPRESSION IN PLANTS |
SG178947A1 (en) | 2009-09-22 | 2012-04-27 | Medicago Inc | Method of preparing plant-derived proteins |
AU2011312178B2 (en) | 2010-10-04 | 2016-05-12 | Massachusetts Institute Of Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
AU2011325827B2 (en) | 2010-11-04 | 2016-08-04 | Medicago Inc. | Plant expression system |
TWI526539B (zh) | 2010-12-22 | 2016-03-21 | 苜蓿股份有限公司 | 植物中生產類病毒顆粒(vlp)的方法及以該方法生產之vlp |
TWI620816B (zh) | 2011-03-23 | 2018-04-11 | 苜蓿股份有限公司 | 植物衍生蛋白回收方法 |
RU2655433C2 (ru) | 2011-06-13 | 2018-05-28 | Медикаго Инк. | Получение вирусоподобной частицы вируса бешенства в растениях |
PL220281B1 (pl) | 2011-09-23 | 2015-09-30 | Inst Biochemii I Biofizyki Polskiej Akademii Nauk | Szczepionka DNA, sposób indukowania odpowiedzi immunologicznej, przeciwciała specyficznie rozpoznające białko hemaglutyniny H5 wirusa grypy i zastosowanie szczepionki DNA |
ES2951259T3 (es) * | 2011-09-30 | 2023-10-19 | Medicago Inc | Aumento del rendimiento de las partículas similares a virus en las plantas |
US20140302158A1 (en) | 2011-11-11 | 2014-10-09 | Phillip Morris Products S.A. | Influenza virus-like particles (vlps) comprising hemagglutinin produced nicotiana tabacum |
EP2876161B1 (en) | 2012-07-23 | 2018-12-05 | The Institute of Biological Resources | Vaccine |
IL241692B2 (en) * | 2013-03-28 | 2023-12-01 | Medicago Inc | Production of influenza virus-like particles in plants |
CN105980561B (zh) * | 2014-01-10 | 2020-06-02 | 莫迪卡戈公司 | Cpmv增强子元件 |
JP6599354B2 (ja) * | 2014-03-27 | 2019-10-30 | メディカゴ インコーポレイテッド | 改変されたcpmvエンハンサーエレメント |
-
2015
- 2015-01-08 CN CN201580007060.9A patent/CN105980561B/zh active Active
- 2015-01-08 RU RU2016132865A patent/RU2699982C2/ru active
- 2015-01-08 AU AU2015205805A patent/AU2015205805B2/en active Active
- 2015-01-08 WO PCT/CA2015/050009 patent/WO2015103704A1/en active Application Filing
- 2015-01-08 US US15/110,696 patent/US11441150B2/en active Active
- 2015-01-08 EP EP15735364.0A patent/EP3092309B1/en active Active
- 2015-01-08 DK DK15735364.0T patent/DK3092309T3/da active
- 2015-01-08 CA CA2936350A patent/CA2936350C/en active Active
- 2015-01-08 ES ES15735364T patent/ES2864081T3/es active Active
- 2015-01-08 JP JP2016545837A patent/JP6518257B2/ja active Active
- 2015-01-08 TW TW104100482A patent/TWI714522B/zh active
- 2015-01-08 BR BR112016015875A patent/BR112016015875A2/pt not_active Application Discontinuation
-
2020
- 2020-05-21 US US16/880,583 patent/US11884929B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
RU2016132865A (ru) | 2018-02-14 |
BR112016015875A2 (pt) | 2017-09-19 |
TWI714522B (zh) | 2021-01-01 |
JP6518257B2 (ja) | 2019-05-22 |
JP2017501738A (ja) | 2017-01-19 |
CA2936350C (en) | 2023-01-31 |
US20170029832A1 (en) | 2017-02-02 |
CN105980561A (zh) | 2016-09-28 |
US11441150B2 (en) | 2022-09-13 |
AU2015205805A1 (en) | 2016-08-04 |
RU2016132865A3 (da) | 2018-08-28 |
ES2864081T3 (es) | 2021-10-13 |
EP3092309A1 (en) | 2016-11-16 |
CA2936350A1 (en) | 2015-07-16 |
CN105980561B (zh) | 2020-06-02 |
WO2015103704A1 (en) | 2015-07-16 |
TW201610154A (zh) | 2016-03-16 |
EP3092309B1 (en) | 2021-02-24 |
AU2015205805B2 (en) | 2020-11-12 |
EP3092309A4 (en) | 2017-06-28 |
US11884929B2 (en) | 2024-01-30 |
US20200283784A1 (en) | 2020-09-10 |
RU2699982C2 (ru) | 2019-09-11 |
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