JP2012530499A5 - - Google Patents
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- JP2012530499A5 JP2012530499A5 JP2012516452A JP2012516452A JP2012530499A5 JP 2012530499 A5 JP2012530499 A5 JP 2012530499A5 JP 2012516452 A JP2012516452 A JP 2012516452A JP 2012516452 A JP2012516452 A JP 2012516452A JP 2012530499 A5 JP2012530499 A5 JP 2012530499A5
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- JP
- Japan
- Prior art keywords
- nucleic acid
- influenza
- plant
- virus
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22016109P | 2009-06-24 | 2009-06-24 | |
| US61/220,161 | 2009-06-24 | ||
| PCT/CA2010/000983 WO2010148511A1 (en) | 2009-06-24 | 2010-06-25 | Chimeric influenza virus-like particles comprising hemagglutinin |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014076395A Division JP6141228B2 (ja) | 2009-06-24 | 2014-04-02 | ヘマグルチニンを含むキメラインフルエンザウイルス様粒子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012530499A JP2012530499A (ja) | 2012-12-06 |
| JP2012530499A5 true JP2012530499A5 (enExample) | 2013-05-30 |
| JP5871796B2 JP5871796B2 (ja) | 2016-03-01 |
Family
ID=43385835
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012516452A Active JP5871796B2 (ja) | 2009-06-24 | 2010-06-25 | ヘマグルチニンを含むキメラインフルエンザウイルス様粒子 |
| JP2014076395A Active JP6141228B2 (ja) | 2009-06-24 | 2014-04-02 | ヘマグルチニンを含むキメラインフルエンザウイルス様粒子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014076395A Active JP6141228B2 (ja) | 2009-06-24 | 2014-04-02 | ヘマグルチニンを含むキメラインフルエンザウイルス様粒子 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US10272148B2 (enExample) |
| EP (2) | EP3228627A1 (enExample) |
| JP (2) | JP5871796B2 (enExample) |
| KR (1) | KR101377725B1 (enExample) |
| CN (1) | CN102482328B (enExample) |
| AU (1) | AU2010265766B2 (enExample) |
| BR (1) | BRPI1015053A2 (enExample) |
| CA (1) | CA2762042C (enExample) |
| DK (1) | DK2445928T3 (enExample) |
| ES (1) | ES2669303T3 (enExample) |
| HK (1) | HK1245294A1 (enExample) |
| HR (1) | HRP20180706T1 (enExample) |
| HU (1) | HUE039100T2 (enExample) |
| IL (1) | IL216937A (enExample) |
| IN (1) | IN2012DN00650A (enExample) |
| MX (2) | MX349924B (enExample) |
| MY (1) | MY182643A (enExample) |
| NO (1) | NO2445928T3 (enExample) |
| NZ (1) | NZ597401A (enExample) |
| PL (1) | PL2445928T3 (enExample) |
| PT (1) | PT2445928T (enExample) |
| SG (1) | SG176820A1 (enExample) |
| SI (1) | SI2445928T1 (enExample) |
| WO (1) | WO2010148511A1 (enExample) |
| ZA (1) | ZA201200481B (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2615372A1 (en) * | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| NZ587108A (en) | 2007-11-27 | 2013-04-26 | Medicago Inc | Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin |
| DK2294202T3 (en) * | 2008-07-08 | 2015-08-31 | Medicago Inc | SOLUBLE RECOMBINANT INFLUENZA ANTIGENES |
| JP2012521786A (ja) | 2009-03-30 | 2012-09-20 | モウント シナイ スクール オフ メディシネ | インフルエンザウイルスワクチン及びその使用 |
| WO2010138564A1 (en) | 2009-05-26 | 2010-12-02 | Mount Sinai School Of Medicine Of New York University | Monoclonal antibodies against influenza virus generated by cyclical administration and uses thereof |
| SI2445928T1 (en) | 2009-06-24 | 2018-05-31 | Medicago Inc. | HYPER PARTICULARS, SIMILAR VIRUSES OF GRIPE, WHICH HAVE EXPOSED HEMAGLUTININE |
| SG178918A1 (en) | 2009-09-22 | 2012-04-27 | Medicago Inc | Method of preparing plant-derived vlps |
| US9701723B2 (en) | 2010-02-18 | 2017-07-11 | Icahn School Of Medicine At Mount Sinai | Vaccines for use in the prophylaxis and treatment of influenza virus disease |
| MX2012011300A (es) | 2010-03-30 | 2012-11-29 | Sinai School Medicine | Vacunas del virus de influenza y usos de las mismas. |
| TWI526539B (zh) | 2010-12-22 | 2016-03-21 | 苜蓿股份有限公司 | 植物中生產類病毒顆粒(vlp)的方法及以該方法生產之vlp |
| CN103562389B (zh) * | 2011-02-08 | 2020-06-23 | 淡马锡生命科学研究院有限公司 | 用于有效表面展示抗原蛋白的新颖表达盒 |
| TWI620816B (zh) | 2011-03-23 | 2018-04-11 | 苜蓿股份有限公司 | 植物衍生蛋白回收方法 |
| EP3418300B1 (en) | 2011-07-18 | 2020-10-28 | Institute for Research in Biomedicine | Neutralizing anti-influenza a virus antibodies and uses thereof |
| HK1200102A1 (en) * | 2011-09-20 | 2015-07-31 | 西奈山医学院 | Influenza virus vaccines and uses thereof |
| TWI700368B (zh) | 2011-09-30 | 2020-08-01 | 苜蓿股份有限公司 | 增加植物類病毒顆粒產率 |
| US11390878B2 (en) | 2011-09-30 | 2022-07-19 | Medicago Inc. | Increasing protein yield in plants |
| SG11201503989PA (en) * | 2012-11-27 | 2015-06-29 | Univ Pittsburgh | Computationally optimized broadly reactive antigens for h1n1 influenza |
| NZ627796A (en) | 2012-12-18 | 2017-07-28 | Icahn School Med Mount Sinai | Influenza virus vaccines and uses thereof |
| US9908930B2 (en) | 2013-03-14 | 2018-03-06 | Icahn School Of Medicine At Mount Sinai | Antibodies against influenza virus hemagglutinin and uses thereof |
| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| JP2016516415A (ja) * | 2013-03-28 | 2016-06-09 | メディカゴ インコーポレイテッド | 植物におけるインフルエンザウイルス様粒子の生成 |
| CA2914604A1 (en) * | 2013-06-06 | 2014-12-11 | Novartis Ag | Influenza virus reassortment |
| BR112016015875A2 (pt) * | 2014-01-10 | 2017-09-19 | Medicago Inc | Elementos intensificadores de cpmv |
| AU2015234595B2 (en) | 2014-03-27 | 2021-03-25 | Medicago Inc. | Modified CPMV enhancer elements |
| CN105233302B (zh) * | 2014-07-10 | 2018-10-19 | 中国人民解放军军事医学科学院生物工程研究所 | 一种流感血凝素糖蛋白多聚物纳米颗粒的制备方法 |
| EP3247389A4 (en) * | 2015-01-23 | 2019-10-30 | Icahn School of Medicine at Mount Sinai | INFLUENZAVIRUSSCHUTZIMPFPLÄNE |
| RU2728472C2 (ru) | 2015-07-02 | 2020-07-29 | Медикаго Инк. | Активатор сигнального пути жасмоновой кислоты |
| KR101755114B1 (ko) * | 2015-09-08 | 2017-07-06 | 건국대학교 산학협력단 | 여러 클레이드의 고병원성 조류인플루엔자 h5 바이러스에 대한 넓은 항체 반응을 유도하는 키메릭 바이러스 유사입자 백신 |
| WO2017087492A1 (en) * | 2015-11-16 | 2017-05-26 | Kansas State University Research Foundation | Influenza virus vaccine and vaccine platform |
| KR102748840B1 (ko) * | 2016-02-03 | 2025-01-02 | 씨지 디스커버리, 인코포레이티드 | 이종 에피토프 및/또는 성숙 절단 부위를 갖는 인플루엔자 헤마글루티닌 조성물 |
| MX2018015755A (es) | 2016-06-15 | 2019-08-29 | Icahn School Med Mount Sinai | Proteinas de hemaglutinina de virus de influenza y usos de las mismas. |
| US20180128545A1 (en) | 2016-11-08 | 2018-05-10 | Berry Metal Company | Modular furnace cooling wall |
| CA3058652A1 (en) | 2017-04-07 | 2018-10-11 | Icahn School Of Medicine At Mount Sinai | Anti-influenza b virus neuraminidase antibodies and uses thereof |
| JP6622825B2 (ja) * | 2018-01-25 | 2019-12-18 | インスティテュート・フォー・リサーチ・イン・バイオメディシンＩｎｓｔｉｔｕｔｅ Ｆｏｒ Ｒｅｓｅａｒｃｈ Ｉｎ Ｂｉｏｍｅｄｉｃｉｎｅ | Ａ型インフルエンザウイルス中和抗体及びその使用法 |
| JP7423875B6 (ja) | 2018-03-14 | 2024-03-15 | メディカゴ インコーポレイテッド | 植物発現エンハンサ |
| US12364746B2 (en) | 2018-06-21 | 2025-07-22 | Icahn School Of Medicine At Mount Sinai | Mosaic influenza virus hemagglutinin polypeptides and uses thereof |
| AU2019295495B2 (en) | 2018-06-27 | 2025-05-22 | Aramis Biotechnologies Inc. | Influenza virus hemagglutinin mutants |
| BR112021017899A2 (pt) | 2019-03-14 | 2021-12-21 | Medicago Inc | Intensificador de expressão vegetal endógeno |
| US12384811B2 (en) | 2019-04-05 | 2025-08-12 | Academia Sinica | Sialidase-resistant saccharide and method of making and using the same |
| CA3137160A1 (en) | 2019-04-24 | 2020-10-29 | Icahn School Of Medicine At Mount Sinai | Anti-influenza b virus neuraminidase antibodies and uses thereof |
| TWI817041B (zh) * | 2019-09-20 | 2023-10-01 | 中央研究院 | 嵌合血球凝集素蛋白質及包含其之疫苗組成物 |
| JP2020048568A (ja) * | 2019-11-22 | 2020-04-02 | インスティテュート・フォー・リサーチ・イン・バイオメディシンＩｎｓｔｉｔｕｔｅ Ｆｏｒ Ｒｅｓｅａｒｃｈ Ｉｎ Ｂｉｏｍｅｄｉｃｉｎｅ | Ａ型インフルエンザウイルス中和抗体及びその使用法 |
| KR20230038416A (ko) * | 2020-05-08 | 2023-03-20 | 아카데미아 시니카 | 키메릭 인플루엔자 백신 |
| TWI867291B (zh) | 2021-04-12 | 2024-12-21 | 中央研究院 | 經改良之冠狀病毒疫苗 |
| TW202334429A (zh) | 2021-10-01 | 2023-09-01 | 中央研究院 | Sars-cov-2棘蛋白特異性抗體及其用途 |
| AU2024252371B2 (en) | 2023-04-08 | 2026-02-12 | Rock Biomedical Inc. | Methods and compositions for dendritic cell targeting nano-delivery |
| EP4568709A2 (en) | 2023-04-08 | 2025-06-18 | Rock Biomedical Inc. | Methods and compositions for targeted delivery by polymersomes |
| EP4713441A2 (en) | 2023-05-17 | 2026-03-25 | Rock Biomedical Inc. | Mgat1 deficient cells and uses thereof |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428147A (en) | 1983-04-15 | 1995-06-27 | Mycogen Plant Science, Inc. | Octopine T-DNA promoters |
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5036006A (en) | 1984-11-13 | 1991-07-30 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5100792A (en) | 1984-11-13 | 1992-03-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues |
| EP0203177A4 (en) | 1984-11-29 | 1987-04-28 | Scripps Clinic Res | POLYPEPTIDES AND ANTIBODIES ASSOCIATED WITH VIRAL GLUCOPROTEINS WITHOUT GLUCOSE. |
| US4962028A (en) | 1986-07-09 | 1990-10-09 | Dna Plant Technology Corporation | Plant promotors |
| US5232833A (en) | 1988-09-14 | 1993-08-03 | Stressgen Biotechnologies Corporation | Accumulation of heat shock proteins for evaluating biological damage due to chronic exposure of an organism to sublethal levels of pollutants |
| US6403865B1 (en) | 1990-08-24 | 2002-06-11 | Syngenta Investment Corp. | Method of producing transgenic maize using direct transformation of commercially important genotypes |
| ATE142883T1 (de) | 1991-03-28 | 1996-10-15 | Rooperol Na Nv | Zusammensetzungen von phytosterolen mit phytosterolinen als immunmodulatoren |
| UA48104C2 (uk) | 1991-10-04 | 2002-08-15 | Новартіс Аг | Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника |
| US6326470B1 (en) | 1997-04-15 | 2001-12-04 | The Penn State Research Foundation | Enhancement of accessibility of cellulose by expansins |
| US5762939A (en) | 1993-09-13 | 1998-06-09 | Mg-Pmc, Llc | Method for producing influenza hemagglutinin multivalent vaccines using baculovirus |
| GB9414118D0 (en) | 1994-07-13 | 1994-08-31 | Axis Genetics Ltd | Modified plant viruses as vectors of heterologous peptides |
| US6020169A (en) | 1995-07-20 | 2000-02-01 | Washington State University Research Foundation | Production of secreted foreign polypeptides in plant cell culture |
| US6042832A (en) | 1996-08-28 | 2000-03-28 | Thomas Jefferson University | Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid proteins |
| US20010006950A1 (en) | 1998-02-11 | 2001-07-05 | Juha Punnonen | Genetic vaccine vector engineering |
| US6489537B1 (en) | 1998-08-07 | 2002-12-03 | The Trustees Of The University Of Pennsylvania | Phytochelatin synthases and uses therefor |
| MXPA01001445A (es) | 1998-08-11 | 2002-11-29 | Large Scale Biology Corp | Metodo para recuperar proteinas a partir del fluido intersticial de tejidos de plantas. |
| US6392121B1 (en) | 1998-10-07 | 2002-05-21 | Boyce Thompson Institute For Plant Research | Gemini virus vectors for gene expression in plants |
| US6287570B1 (en) | 1998-11-23 | 2001-09-11 | Patricia L. Foley | Vaccine against swine influenza virus |
| FR2791358B1 (fr) | 1999-03-22 | 2003-05-16 | Meristem Therapeutics | Promoteurs chimeriques d'expression, cassettes d'expression, plasmides, vecteurs, plantes et semences transgeniques les contenant et leurs methodes d'obtention |
| ES2262514T3 (es) * | 1999-04-29 | 2006-12-01 | Syngenta Limited | Plantas resistentes a herbicidas. |
| PT1222292E (pt) | 1999-10-04 | 2005-11-30 | Medicago Inc | Metodo para regulacao da transcricao de genes exogenos na presenca de azoto |
| US7125978B1 (en) | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
| US7449188B2 (en) | 2001-01-18 | 2008-11-11 | Vlaams Interuniversitair Instituut Voor Biotechnologie | Recombinant oligometric protein complexes with enhanced immunogenic potential |
| CA2816242C (en) * | 2002-02-13 | 2019-01-08 | Wisconsin Alumni Research Foundation | Signal for packaging of influenza virus vectors |
| AU2003219745B8 (en) | 2002-02-13 | 2008-10-09 | Wisconsin Alumni Research Foundation | Signal for packaging of influenza virus vectors |
| US7041500B2 (en) | 2002-02-14 | 2006-05-09 | Novavax, Inc. | Insect cell line |
| EP2319935B1 (en) | 2002-03-19 | 2016-04-27 | Stichting Dienst Landbouwkundig Onderzoek | GnTIII (UDP-N-acetylglucosamine:Beta -D mannoside Beta (1,4)-N-acetylglucosaminyltransferase III) expression in plants. |
| ES2224792B1 (es) | 2002-06-28 | 2007-02-16 | Era Plantech, S.L. | Produccion de peptidos y proteinas por acumulacion de cuerpos proteicos derivados de reticulos endoplasmico en plantas. |
| NZ542933A (en) | 2003-05-05 | 2009-08-28 | Dow Agrosciences Llc | Stable immunoprophylactic and therapeutic compositions derived from transgenic plant cells and methods for production |
| AU2004235813B2 (en) | 2003-05-05 | 2010-07-29 | Boyce Thompson Institute For Plant Research | Vectors and cells for preparing immunoprotective compositions derived from transgenic plants |
| WO2005018539A2 (en) | 2003-06-16 | 2005-03-03 | Medimmune Vaccines, Inc. | Influenza hemagglutinin and neuraminidase variants |
| US8592197B2 (en) | 2003-07-11 | 2013-11-26 | Novavax, Inc. | Functional influenza virus-like particles (VLPs) |
| US7226781B1 (en) | 2003-07-24 | 2007-06-05 | Belyaev Alexander S | Chaperone expression genomes |
| ES2662118T3 (es) | 2005-04-29 | 2018-04-05 | University Of Cape Town | Expresión de proteínas virales en las plantas |
| CA2615658A1 (en) | 2005-07-19 | 2007-01-25 | Dow Global Technolgies Inc. | Recombinant flu vaccines |
| US7871626B2 (en) | 2005-08-04 | 2011-01-18 | St. Jude Children's Research Hospital | Modified influenza virus for monitoring and improving vaccine efficiency |
| EP1945250A4 (en) | 2005-08-16 | 2010-05-19 | Hawaii Biotech Inc | RECOMBINANT SUBUNIT VACCINE AGAINST INFLUENZA |
| RU2483751C2 (ru) | 2005-10-18 | 2013-06-10 | Новавакс, Инк. | ФУНКЦИОНАЛЬНЫЕ ВИРУСОПОДОБНЫЕ ЧАСТИЦЫ ГРИППА (VLPs) |
| EP1984405A4 (en) | 2006-02-13 | 2010-06-30 | Fraunhofer Usa Inc | INFLUENZA ANTIGENES, VACCINE COMPOSITIONS AND RELATED METHODS |
| KR20080109094A (ko) | 2006-04-21 | 2008-12-16 | 다우 아그로사이언시즈 엘엘씨 | 조류 인플루엔자 백신 및 이용방법 |
| US8778353B2 (en) | 2006-05-01 | 2014-07-15 | Technovax, Inc. | Influenza virus-like particle (VLP) compositions |
| WO2008054540A2 (en) | 2006-05-18 | 2008-05-08 | Pharmexa Inc. | Inducing immune responses to influenza virus using polypeptide and nucleic acid compositions |
| EP2029755A1 (en) | 2006-05-22 | 2009-03-04 | Plant Bioscience Limited | Bipartite system, method and composition for the constitutive and inducible expression of high levels of foreign proteins in plants |
| US20070286873A1 (en) | 2006-05-23 | 2007-12-13 | Williams John V | Recombinant Influenza H5 Hemagluttinin Protein And Nucleic Acid Coding Therefor |
| US20100143406A1 (en) | 2006-06-30 | 2010-06-10 | Gale Smith | Methods of enhancing protein incorporation into virus like particles |
| US20080233150A1 (en) | 2006-11-16 | 2008-09-25 | Gale Smith | Respiratory syncytial virus-virus like particle (vlps) |
| US7730950B2 (en) | 2007-01-19 | 2010-06-08 | Halliburton Energy Services, Inc. | Methods for treating intervals of a subterranean formation having variable permeability |
| WO2008148104A1 (en) | 2007-05-25 | 2008-12-04 | Novavax, Inc. | Novel vlps derived from cells that do not express a viral matrix or core protein |
| CN104962579A (zh) | 2007-06-15 | 2015-10-07 | 麦迪卡格公司 | 修饰植物中的糖蛋白产生 |
| KR100964462B1 (ko) | 2007-07-10 | 2010-06-16 | 성균관대학교산학협력단 | 형질전환 식물 유래의 조류독감 바이러스 백신 및 그 제조방법 |
| CA2615372A1 (en) * | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| CA2696764A1 (en) | 2007-08-20 | 2009-02-26 | Fraunhofer Usa, Inc. | Prophylactic and therapeutic influenza vaccines, antigens, compositions, and methods |
| NZ587108A (en) | 2007-11-27 | 2013-04-26 | Medicago Inc | Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin |
| GB0800272D0 (en) | 2008-01-08 | 2008-02-13 | Plant Bioscience Ltd | Protein expression systems |
| SG187500A1 (en) | 2008-01-21 | 2013-02-28 | Medicago Inc | Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin |
| DK2294202T3 (en) | 2008-07-08 | 2015-08-31 | Medicago Inc | SOLUBLE RECOMBINANT INFLUENZA ANTIGENES |
| KR101745925B1 (ko) | 2008-07-18 | 2017-06-12 | 메디카고 인코포레이티드 | 신규 인플루엔자 바이러스 면역화 에피토프 |
| CA2736796A1 (en) | 2008-08-27 | 2010-03-04 | Arizona Board Of Regents For And On Behalf Of Arizona State University | A dna replicon system for high-level rapid production of vaccines and monoclonal antibody therapeutics in plants |
| US20100167376A1 (en) | 2008-10-06 | 2010-07-01 | Genvault Corporation | Methods for providing cellular lysates from cell wall-containing samples |
| WO2010077712A1 (en) | 2008-12-09 | 2010-07-08 | Novavax, Inc. | Bovine respiratory syncytial virus virus-like particle (vlps) |
| SI2445928T1 (en) | 2009-06-24 | 2018-05-31 | Medicago Inc. | HYPER PARTICULARS, SIMILAR VIRUSES OF GRIPE, WHICH HAVE EXPOSED HEMAGLUTININE |
| SG178918A1 (en) | 2009-09-22 | 2012-04-27 | Medicago Inc | Method of preparing plant-derived vlps |
-
2010
- 2010-06-25 SI SI201031674T patent/SI2445928T1/en unknown
- 2010-06-25 MY MYPI2011006238A patent/MY182643A/en unknown
- 2010-06-25 MX MX2011013517A patent/MX349924B/es active IP Right Grant
- 2010-06-25 CA CA2762042A patent/CA2762042C/en active Active
- 2010-06-25 AU AU2010265766A patent/AU2010265766B2/en active Active
- 2010-06-25 EP EP17152741.9A patent/EP3228627A1/en not_active Ceased
- 2010-06-25 HR HRP20180706TT patent/HRP20180706T1/hr unknown
- 2010-06-25 SG SG2011092103A patent/SG176820A1/en unknown
- 2010-06-25 ES ES10791119.0T patent/ES2669303T3/es active Active
- 2010-06-25 WO PCT/CA2010/000983 patent/WO2010148511A1/en not_active Ceased
- 2010-06-25 CN CN201080035066.4A patent/CN102482328B/zh active Active
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- 2010-06-25 HU HUE10791119A patent/HUE039100T2/hu unknown
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- 2010-06-25 DK DK10791119.0T patent/DK2445928T3/en active
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