JP2011528223A5 - - Google Patents
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- Publication number
- JP2011528223A5 JP2011528223A5 JP2011517725A JP2011517725A JP2011528223A5 JP 2011528223 A5 JP2011528223 A5 JP 2011528223A5 JP 2011517725 A JP2011517725 A JP 2011517725A JP 2011517725 A JP2011517725 A JP 2011517725A JP 2011528223 A5 JP2011528223 A5 JP 2011528223A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- plant
- vlp
- glycosylation
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8181108P | 2008-07-18 | 2008-07-18 | |
| US61/081,811 | 2008-07-18 | ||
| PCT/CA2009/001040 WO2010006452A1 (en) | 2008-07-18 | 2009-07-15 | New influenza virus immunizing epitope |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011528223A JP2011528223A (ja) | 2011-11-17 |
| JP2011528223A5 true JP2011528223A5 (enExample) | 2012-09-06 |
| JP5813505B2 JP5813505B2 (ja) | 2015-11-17 |
Family
ID=41549982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011517725A Expired - Fee Related JP5813505B2 (ja) | 2008-07-18 | 2009-07-15 | 新規インフルエンザウイルス免疫エピトープ |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9546375B2 (enExample) |
| EP (1) | EP2318530B1 (enExample) |
| JP (1) | JP5813505B2 (enExample) |
| KR (1) | KR101745925B1 (enExample) |
| CN (1) | CN102165062B (enExample) |
| AU (1) | AU2009270404B2 (enExample) |
| CA (1) | CA2730668C (enExample) |
| DK (1) | DK2318530T3 (enExample) |
| ES (1) | ES2593277T3 (enExample) |
| IL (1) | IL210451A (enExample) |
| MX (2) | MX370690B (enExample) |
| MY (1) | MY161965A (enExample) |
| NZ (1) | NZ590351A (enExample) |
| PT (1) | PT2318530T (enExample) |
| RU (1) | RU2546872C2 (enExample) |
| SG (1) | SG192503A1 (enExample) |
| WO (1) | WO2010006452A1 (enExample) |
| ZA (1) | ZA201101231B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| CN103122354B (zh) | 2007-11-27 | 2018-03-23 | 麦迪卡格公司 | 表达血凝素之转基因植物中生产的重组流感病毒样颗粒(vlp) |
| US8771703B2 (en) * | 2008-07-08 | 2014-07-08 | Medicago Inc. | Soluble recombinant influenza antigens |
| AU2009270404B2 (en) | 2008-07-18 | 2015-01-29 | Medicago Inc. | New influenza virus immunizing epitope |
| CA2762042C (en) | 2009-06-24 | 2012-11-20 | Medicago Inc. | Chimeric influenza virus-like particles comprising hemagglutinin |
| CA2766899C (en) | 2009-07-02 | 2021-05-04 | Massachusetts Institute Of Technology | Compositions and methods for diagnosing and/or treating influenza infection |
| HRP20171564T1 (hr) | 2009-09-22 | 2017-11-17 | Medicago Inc. | Postupak za pripremu biljnih čestica sličnih virusu (vlp) |
| JP2013541528A (ja) | 2010-09-21 | 2013-11-14 | マサチューセッツ インスティテュート オブ テクノロジー | ヒト適応ｈａポリペプチド、ワクチン、およびインフルエンザの処置 |
| AU2011312178B2 (en) | 2010-10-04 | 2016-05-12 | Massachusetts Institute Of Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
| WO2012088428A1 (en) * | 2010-12-22 | 2012-06-28 | Novavax Inc. | Modified influenza hemagglutinin proteins and uses thereof |
| TWI620816B (zh) | 2011-03-23 | 2018-04-11 | 苜蓿股份有限公司 | 植物衍生蛋白回收方法 |
| MX350421B (es) * | 2011-06-13 | 2017-09-06 | Medicago Inc | Producción de partículas tipo virus de la rabia en plantas. |
| SI2760882T1 (sl) | 2011-09-30 | 2023-10-30 | Medicago Inc. | Povečanje količine virusom podobnih delcev v rastlinah |
| US11390878B2 (en) | 2011-09-30 | 2022-07-19 | Medicago Inc. | Increasing protein yield in plants |
| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| JP2016516415A (ja) | 2013-03-28 | 2016-06-09 | メディカゴ インコーポレイテッド | 植物におけるインフルエンザウイルス様粒子の生成 |
| EP3039036B1 (en) | 2013-08-28 | 2019-05-22 | GlaxoSmithKline Biologicals S.A. | Novel influenza antigens and antibodies |
| US10291197B2 (en) | 2016-02-03 | 2019-05-14 | Cg Discovery, Inc. | Compositions of influenza hemagglutinin with heterologous epitopes and/or altered maturation cleavage sites and methods of use thereof |
| GB201614485D0 (en) * | 2016-08-25 | 2016-10-12 | Univ Oxford Innovation Ltd | Immunogenic composition |
| US20180128545A1 (en) * | 2016-11-08 | 2018-05-10 | Berry Metal Company | Modular furnace cooling wall |
| CA3079486A1 (en) * | 2017-10-18 | 2019-04-25 | Xiamen University | Mutant of hemagglutinin protein of h3n2 subtype influenza virus and use thereof |
| MX2020013961A (es) | 2018-06-27 | 2021-03-09 | Medicago Inc | Mutantes de hemaglutinina del virus de la influenza. |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428147A (en) | 1983-04-15 | 1995-06-27 | Mycogen Plant Science, Inc. | Octopine T-DNA promoters |
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5100792A (en) | 1984-11-13 | 1992-03-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues |
| US5036006A (en) | 1984-11-13 | 1991-07-30 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| WO1986003224A1 (en) | 1984-11-29 | 1986-06-05 | Scripps Clinic And Research Foundation | Polypeptides and antibodies related to deglycosylated viral glycoproteins |
| US4962028A (en) | 1986-07-09 | 1990-10-09 | Dna Plant Technology Corporation | Plant promotors |
| US5312746A (en) * | 1993-01-08 | 1994-05-17 | Life Technologies, Inc. | Cloning and expressing restriction endonucleases and modification methylases from caryophanon |
| GB9414118D0 (en) | 1994-07-13 | 1994-08-31 | Axis Genetics Ltd | Modified plant viruses as vectors of heterologous peptides |
| GB9524350D0 (en) | 1995-11-29 | 1996-01-31 | Lynxvale Ltd | Enhancer-increased gene expression in plants |
| US6042832A (en) * | 1996-08-28 | 2000-03-28 | Thomas Jefferson University | Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid proteins |
| US5945326A (en) * | 1997-03-20 | 1999-08-31 | New England Biolabs, Inc. | Method for cloning and producing the Spel restriction endonuclease |
| US20010006950A1 (en) * | 1998-02-11 | 2001-07-05 | Juha Punnonen | Genetic vaccine vector engineering |
| US6489537B1 (en) * | 1998-08-07 | 2002-12-03 | The Trustees Of The University Of Pennsylvania | Phytochelatin synthases and uses therefor |
| US6287570B1 (en) | 1998-11-23 | 2001-09-11 | Patricia L. Foley | Vaccine against swine influenza virus |
| US7125978B1 (en) * | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
| WO2001029242A2 (en) | 1999-10-21 | 2001-04-26 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
| WO2001031045A1 (en) | 1999-10-26 | 2001-05-03 | Plant Research International B.V. | Mammalian-type glycosylation in plants |
| CN100385006C (zh) | 2001-01-19 | 2008-04-30 | 陶氏化学公司 | 利用植物细胞分泌性生产具有人型糖链的糖蛋白的方法 |
| HUE050222T2 (hu) * | 2002-02-13 | 2020-11-30 | Wisconsin Alumni Res Found | Szignál influenzavírus-vektorok pakolására |
| EP1485492B1 (en) * | 2002-03-19 | 2011-12-21 | Stichting Dienst Landbouwkundig Onderzoek | Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta(1,4)-n-acetylglucosaminyltransferase iii) expression in plants |
| JP4532118B2 (ja) * | 2002-03-19 | 2010-08-25 | スティヒティング ディーンスト ランドバウクンディフ オンデルズーク | 植物体内のグリカンプロセシングの最適化 |
| US20040264870A1 (en) | 2002-08-20 | 2004-12-30 | Skunes Timothy A. | Optical alignment mount with height adjustment |
| PL224786B1 (pl) | 2003-01-22 | 2017-01-31 | Glycart Biotechnology Ag | Wyizolowany kwas nukleinowy, ssaczy wektor ekspresyjny, komórki gospodarza, fuzja polipeptydowa i sposób jej wytwarzania, sposoby in vitro i ex vivo modyfikowania profilu glikozylacji polipeptydu wytwarzanego przez komórki gospodarza |
| DE602004028004D1 (de) * | 2003-05-05 | 2010-08-19 | Thompson Boyce Plant Res | Vektoren und zellen zur herstellung von aus transgenen pflanzen gewonnenen immunprotektiven zusammensetzungen |
| CA2816222A1 (en) * | 2003-06-16 | 2005-03-03 | Medimmune Vaccines, Inc. | Influenza hemagglutinin and neuraminidase variants |
| US8592197B2 (en) * | 2003-07-11 | 2013-11-26 | Novavax, Inc. | Functional influenza virus-like particles (VLPs) |
| US7723569B2 (en) | 2004-04-30 | 2010-05-25 | National Institute Of Agrobiological Sciences | Method for producing ubiquinone-10 in plant |
| WO2006119516A2 (en) | 2005-04-29 | 2006-11-09 | University Of Cape Town | Expression of viral proteins in plants |
| MX2008000890A (es) | 2005-07-19 | 2008-03-18 | Dow Global Technologies Inc | Vacunas de influenza (flu) recombinantes. |
| US7871626B2 (en) | 2005-08-04 | 2011-01-18 | St. Jude Children's Research Hospital | Modified influenza virus for monitoring and improving vaccine efficiency |
| BRPI0617486A2 (pt) | 2005-10-18 | 2011-07-26 | Novavax Inc | vacina que compreende partÍculas similares a vÍrus da gripe funcionais (vlp) e uso de uma vlp de gripe |
| WO2007051036A2 (en) * | 2005-10-26 | 2007-05-03 | Protelix, Inc. | Influenza combinatorial antigen vaccine |
| AU2007215080A1 (en) | 2006-02-13 | 2007-08-23 | Fraunhofer Usa, Inc. | Influenza antigens, vaccine compositions, and related methods |
| WO2007130327A2 (en) * | 2006-05-01 | 2007-11-15 | Technovax, Inc. | Influenza virus-like particle (vlp) compositions |
| BRPI0713671A2 (pt) * | 2006-06-16 | 2013-12-03 | Dow Agrosciences Llc | Sequências de dna, vetores e proteínas de hemaglutinina de influenza aviária |
| RU2499053C2 (ru) | 2007-06-15 | 2013-11-20 | Медикаго Инк. | Способ синтеза белка с модифицированным профилем n-гликозилирования в растениях |
| KR100964462B1 (ko) | 2007-07-10 | 2010-06-16 | 성균관대학교산학협력단 | 형질전환 식물 유래의 조류독감 바이러스 백신 및 그 제조방법 |
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| IL203018A (en) | 2007-07-13 | 2015-01-29 | Medicago Inc | Influenza virus-like particles containing megalotinin produced in a plant |
| CN103122354B (zh) | 2007-11-27 | 2018-03-23 | 麦迪卡格公司 | 表达血凝素之转基因植物中生产的重组流感病毒样颗粒(vlp) |
| KR101956910B1 (ko) | 2008-01-21 | 2019-03-12 | 메디카고 인코포레이티드 | 헤마글루티닌을 발현하는 트랜스제닉 식물에서 생산된 재조합 인플루엔자 바이러스-유사 입자(ＶＬＰｓ) |
| AU2009270404B2 (en) | 2008-07-18 | 2015-01-29 | Medicago Inc. | New influenza virus immunizing epitope |
-
2009
- 2009-07-15 AU AU2009270404A patent/AU2009270404B2/en not_active Ceased
- 2009-07-15 MY MYPI2011000210A patent/MY161965A/en unknown
- 2009-07-15 PT PT97973366T patent/PT2318530T/pt unknown
- 2009-07-15 MX MX2014013665A patent/MX370690B/es unknown
- 2009-07-15 KR KR1020117002827A patent/KR101745925B1/ko not_active Expired - Fee Related
- 2009-07-15 JP JP2011517725A patent/JP5813505B2/ja not_active Expired - Fee Related
- 2009-07-15 CN CN200980136376.2A patent/CN102165062B/zh not_active Expired - Fee Related
- 2009-07-15 CA CA2730668A patent/CA2730668C/en active Active
- 2009-07-15 SG SG2013053467A patent/SG192503A1/en unknown
- 2009-07-15 ES ES09797336.6T patent/ES2593277T3/es active Active
- 2009-07-15 US US13/054,452 patent/US9546375B2/en not_active Expired - Fee Related
- 2009-07-15 RU RU2011105885/10A patent/RU2546872C2/ru active
- 2009-07-15 WO PCT/CA2009/001040 patent/WO2010006452A1/en not_active Ceased
- 2009-07-15 DK DK09797336.6T patent/DK2318530T3/en active
- 2009-07-15 NZ NZ590351A patent/NZ590351A/xx unknown
- 2009-07-15 MX MX2011000657A patent/MX2011000657A/es active IP Right Grant
- 2009-07-15 EP EP09797336.6A patent/EP2318530B1/en active Active
-
2011
- 2011-01-04 IL IL210451A patent/IL210451A/en active IP Right Grant
- 2011-02-16 ZA ZA2011/01231A patent/ZA201101231B/en unknown
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