JP2011528223A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011528223A5 JP2011528223A5 JP2011517725A JP2011517725A JP2011528223A5 JP 2011528223 A5 JP2011528223 A5 JP 2011528223A5 JP 2011517725 A JP2011517725 A JP 2011517725A JP 2011517725 A JP2011517725 A JP 2011517725A JP 2011528223 A5 JP2011528223 A5 JP 2011528223A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- plant
- vlp
- glycosylation
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8181108P | 2008-07-18 | 2008-07-18 | |
| US61/081,811 | 2008-07-18 | ||
| PCT/CA2009/001040 WO2010006452A1 (en) | 2008-07-18 | 2009-07-15 | New influenza virus immunizing epitope |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011528223A JP2011528223A (ja) | 2011-11-17 |
| JP2011528223A5 true JP2011528223A5 (enExample) | 2012-09-06 |
| JP5813505B2 JP5813505B2 (ja) | 2015-11-17 |
Family
ID=41549982
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011517725A Expired - Fee Related JP5813505B2 (ja) | 2008-07-18 | 2009-07-15 | 新規インフルエンザウイルス免疫エピトープ |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9546375B2 (enExample) |
| EP (1) | EP2318530B1 (enExample) |
| JP (1) | JP5813505B2 (enExample) |
| KR (1) | KR101745925B1 (enExample) |
| CN (1) | CN102165062B (enExample) |
| AU (1) | AU2009270404B2 (enExample) |
| CA (1) | CA2730668C (enExample) |
| DK (1) | DK2318530T3 (enExample) |
| ES (1) | ES2593277T3 (enExample) |
| IL (1) | IL210451A (enExample) |
| MX (2) | MX2011000657A (enExample) |
| MY (1) | MY161965A (enExample) |
| NZ (1) | NZ590351A (enExample) |
| PT (1) | PT2318530T (enExample) |
| RU (1) | RU2546872C2 (enExample) |
| SG (1) | SG192503A1 (enExample) |
| WO (1) | WO2010006452A1 (enExample) |
| ZA (1) | ZA201101231B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| PT2610345E (pt) | 2007-11-27 | 2016-01-11 | Medicago Inc | Partículas semelhantes ao vírus (vlps) da gripe recombinantes produzidas em plantas transgénicas que expressam hemaglutinina |
| EP2294202B1 (en) | 2008-07-08 | 2015-05-20 | Medicago Inc. | Soluble recombinant influenza antigens |
| CN102165062B (zh) | 2008-07-18 | 2017-09-08 | 麦迪卡格公司 | 新的流感病毒免疫表位 |
| JP5871796B2 (ja) | 2009-06-24 | 2016-03-01 | メディカゴ インコーポレイテッド | ヘマグルチニンを含むキメラインフルエンザウイルス様粒子 |
| WO2011003100A2 (en) | 2009-07-02 | 2011-01-06 | Massachusetts Institute Of Technology | Compositions and methods for diagnosing and/or treating influenza infection |
| ES2662778T3 (es) | 2009-09-22 | 2018-04-09 | Medicago Inc. | Método de preparación de proteínas derivadas de plantas |
| EP2640405A4 (en) | 2010-09-21 | 2015-04-15 | Massachusetts Inst Technology | HA-POLYPEPTIDES ADAPTED TO HUMANS, VACCINES THEREOF AND INFLUENZA TREATMENT THEREWITH |
| SG10201709806VA (en) | 2010-10-04 | 2017-12-28 | Massachusetts Inst Technology | Hemagglutinin polypeptides, and reagents and methods relating thereto |
| SG191295A1 (en) * | 2010-12-22 | 2013-07-31 | Novavax Inc | Modified influenza hemagglutinin proteins and uses thereof |
| TWI620816B (zh) | 2011-03-23 | 2018-04-11 | 苜蓿股份有限公司 | 植物衍生蛋白回收方法 |
| ES2665512T3 (es) * | 2011-06-13 | 2018-04-26 | Medicago Inc. | Producción de partículas pseudovíricas de la rabia en plantas |
| CN116218900A (zh) | 2011-09-30 | 2023-06-06 | 麦迪卡格公司 | 增加植物中病毒样颗粒的产率 |
| US11390878B2 (en) | 2011-09-30 | 2022-07-19 | Medicago Inc. | Increasing protein yield in plants |
| EP2978848B1 (en) | 2013-03-28 | 2020-05-06 | Medicago Inc. | Influenza virus-like particle production in plants |
| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| ES2739123T3 (es) | 2013-08-28 | 2020-01-29 | Glaxosmithkline Biologicals Sa | Nuevos antígenos y anticuerpos de la gripe |
| EP3411712B1 (en) * | 2016-02-03 | 2025-11-19 | CG Discovery, Inc. | Compositions of influenza hemagglutinin with heterologous epitopes and/or altered maturation cleavage sites |
| GB201614485D0 (en) | 2016-08-25 | 2016-10-12 | Univ Oxford Innovation Ltd | Immunogenic composition |
| US20180128545A1 (en) * | 2016-11-08 | 2018-05-10 | Berry Metal Company | Modular furnace cooling wall |
| AU2018351209B2 (en) * | 2017-10-18 | 2022-11-24 | Xiamen University | Mutant of H3N2 subtype influenza virus hemagglutinin protein and use thereof |
| BR112020026620A8 (pt) | 2018-06-27 | 2022-01-25 | Medicago Inc | Mutantes de hemaglutinina do vírus influenza |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428147A (en) | 1983-04-15 | 1995-06-27 | Mycogen Plant Science, Inc. | Octopine T-DNA promoters |
| US5036006A (en) | 1984-11-13 | 1991-07-30 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5100792A (en) | 1984-11-13 | 1992-03-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues |
| US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| EP0203177A4 (en) | 1984-11-29 | 1987-04-28 | Scripps Clinic Res | POLYPEPTIDES AND ANTIBODIES ASSOCIATED WITH VIRAL GLUCOPROTEINS WITHOUT GLUCOSE. |
| US4962028A (en) | 1986-07-09 | 1990-10-09 | Dna Plant Technology Corporation | Plant promotors |
| US5312746A (en) * | 1993-01-08 | 1994-05-17 | Life Technologies, Inc. | Cloning and expressing restriction endonucleases and modification methylases from caryophanon |
| GB9414118D0 (en) | 1994-07-13 | 1994-08-31 | Axis Genetics Ltd | Modified plant viruses as vectors of heterologous peptides |
| GB9524350D0 (en) | 1995-11-29 | 1996-01-31 | Lynxvale Ltd | Enhancer-increased gene expression in plants |
| US6042832A (en) * | 1996-08-28 | 2000-03-28 | Thomas Jefferson University | Polypeptides fused with alfalfa mosaic virus or ilarvirus capsid proteins |
| US5945326A (en) * | 1997-03-20 | 1999-08-31 | New England Biolabs, Inc. | Method for cloning and producing the Spel restriction endonuclease |
| US20010006950A1 (en) * | 1998-02-11 | 2001-07-05 | Juha Punnonen | Genetic vaccine vector engineering |
| US6489537B1 (en) * | 1998-08-07 | 2002-12-03 | The Trustees Of The University Of Pennsylvania | Phytochelatin synthases and uses therefor |
| US6287570B1 (en) | 1998-11-23 | 2001-09-11 | Patricia L. Foley | Vaccine against swine influenza virus |
| US7125978B1 (en) | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
| EP1224309A2 (en) | 1999-10-21 | 2002-07-24 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
| EP2251426A1 (en) | 1999-10-26 | 2010-11-17 | Stichting Dienst Landbouwkundig Onderzoek | Mammalian-type glycosylation in plants |
| WO2002057468A2 (en) | 2001-01-19 | 2002-07-25 | The Dow Chemical Company | Method for secretory production of glycoprotein having human-type sugar chain using plant cell |
| EP3009507B1 (en) * | 2002-02-13 | 2020-06-24 | Wisconsin Alumini Research Foundation | Signal for packaging of influenza virus vectors |
| NZ534881A (en) * | 2002-03-19 | 2006-09-29 | Plant Res Internat B | Mammalian GnTIII expression in plants |
| CA2799805C (en) * | 2002-03-19 | 2016-05-17 | Stichting Dienst Landbouwkundig Onderzoek | Optimizing glycan processing in plants |
| CN1675572A (zh) | 2002-08-20 | 2005-09-28 | 赛博光学公司 | 能够调整高度的光学对准安装座 |
| PL222222B1 (pl) | 2003-01-22 | 2016-07-29 | Glycart Biotechnology Ag | Sposób wytwarzania polipeptydu |
| CN100393870C (zh) | 2003-05-05 | 2008-06-11 | 波依斯汤普森植物研究所 | 用于制备免疫保护性组合物的载体和来源于转基因植物的细胞 |
| US7566458B2 (en) * | 2003-06-16 | 2009-07-28 | Medimmune, Llc | Influenza hemagglutinin and neuraminidase variants |
| US8592197B2 (en) * | 2003-07-11 | 2013-11-26 | Novavax, Inc. | Functional influenza virus-like particles (VLPs) |
| US7723569B2 (en) | 2004-04-30 | 2010-05-25 | National Institute Of Agrobiological Sciences | Method for producing ubiquinone-10 in plant |
| PT2374892T (pt) | 2005-04-29 | 2018-03-29 | Univ Cape Town | Expressão de proteínas virais em plantas |
| BRPI0613625A2 (pt) | 2005-07-19 | 2011-01-18 | Dow Global Technologies Inc | vacinas da gripe recombinantes |
| US7871626B2 (en) * | 2005-08-04 | 2011-01-18 | St. Jude Children's Research Hospital | Modified influenza virus for monitoring and improving vaccine efficiency |
| TWI488968B (zh) | 2005-10-18 | 2015-06-21 | Novavax Inc | 功能性流行性感冒類病毒顆粒（ＶＬＰｓ） |
| CA2627105A1 (en) * | 2005-10-26 | 2007-05-03 | Protelix, Inc. | Influenza combinatorial antigen vaccine |
| JP2009526526A (ja) | 2006-02-13 | 2009-07-23 | フラウンホーファー ユーエスエー， インコーポレイテッド | インフルエンザ抗原、ワクチン組成物、および関連する方法 |
| WO2007130327A2 (en) * | 2006-05-01 | 2007-11-15 | Technovax, Inc. | Influenza virus-like particle (vlp) compositions |
| AU2007261196A1 (en) * | 2006-06-16 | 2007-12-27 | Dow Agrosciences Llc | Novel dna sequences, vectors and proteins of avian influenza hemagglutinin |
| CN101918559A (zh) | 2007-06-15 | 2010-12-15 | 麦迪卡格公司 | 修饰植物中的糖蛋白产生 |
| KR100964462B1 (ko) | 2007-07-10 | 2010-06-16 | 성균관대학교산학협력단 | 형질전환 식물 유래의 조류독감 바이러스 백신 및 그 제조방법 |
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| IL203018A (en) | 2007-07-13 | 2015-01-29 | Medicago Inc | Influenza virus-like particles containing megalotinin produced in a plant |
| PT2610345E (pt) | 2007-11-27 | 2016-01-11 | Medicago Inc | Partículas semelhantes ao vírus (vlps) da gripe recombinantes produzidas em plantas transgénicas que expressam hemaglutinina |
| EA034733B1 (ru) | 2008-01-21 | 2020-03-13 | Медикаго Инк. | Нуклеиновая кислота для увеличенной экспрессии гемагглютинина вируса гриппа в растении и ее применение |
| CN102165062B (zh) | 2008-07-18 | 2017-09-08 | 麦迪卡格公司 | 新的流感病毒免疫表位 |
-
2009
- 2009-07-15 CN CN200980136376.2A patent/CN102165062B/zh not_active Expired - Fee Related
- 2009-07-15 AU AU2009270404A patent/AU2009270404B2/en not_active Ceased
- 2009-07-15 SG SG2013053467A patent/SG192503A1/en unknown
- 2009-07-15 US US13/054,452 patent/US9546375B2/en not_active Expired - Fee Related
- 2009-07-15 JP JP2011517725A patent/JP5813505B2/ja not_active Expired - Fee Related
- 2009-07-15 EP EP09797336.6A patent/EP2318530B1/en active Active
- 2009-07-15 CA CA2730668A patent/CA2730668C/en active Active
- 2009-07-15 DK DK09797336.6T patent/DK2318530T3/en active
- 2009-07-15 MX MX2011000657A patent/MX2011000657A/es active IP Right Grant
- 2009-07-15 PT PT97973366T patent/PT2318530T/pt unknown
- 2009-07-15 WO PCT/CA2009/001040 patent/WO2010006452A1/en not_active Ceased
- 2009-07-15 MX MX2014013665A patent/MX370690B/es unknown
- 2009-07-15 NZ NZ590351A patent/NZ590351A/xx unknown
- 2009-07-15 RU RU2011105885/10A patent/RU2546872C2/ru active
- 2009-07-15 KR KR1020117002827A patent/KR101745925B1/ko not_active Expired - Fee Related
- 2009-07-15 MY MYPI2011000210A patent/MY161965A/en unknown
- 2009-07-15 ES ES09797336.6T patent/ES2593277T3/es active Active
-
2011
- 2011-01-04 IL IL210451A patent/IL210451A/en active IP Right Grant
- 2011-02-16 ZA ZA2011/01231A patent/ZA201101231B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011528223A5 (enExample) | ||
| JP6957580B2 (ja) | 新規多価ナノ粒子に基づくワクチン | |
| Skarlupka et al. | Universal influenza virus neuraminidase vaccine elicits protective immune responses against human seasonal and pre-pandemic strains | |
| JP2012521786A5 (enExample) | ||
| EP2477650B1 (en) | Virus like particles comprising target proteins fused to plant viral coat proteins | |
| WO2011044152A1 (en) | Protection against pandemic and seasonal strains of influenza | |
| JP2013526849A5 (enExample) | ||
| CN107129973A (zh) | 制备植物来源的vlp的方法 | |
| Venkataraman et al. | Combating human viral diseases: will plant-based vaccines be the answer? | |
| US20110191915A1 (en) | Influenza virus immunizing epitope | |
| TW201102084A (en) | Methods and compositions for immunization against virus | |
| HRP20171213T1 (hr) | Glikoproteinske čestice nalik virusu (vlp) bjesnoće | |
| KR20100032920A (ko) | 식물에서 생산된 헤마글루티닌을 포함하는 인플루엔자 바이러스-유사 입자(ＶＬＰｓ) | |
| US12257302B2 (en) | Universal vaccine platform | |
| KR20140098061A (ko) | Ｈｐｖ 키메라 입자 | |
| Guo et al. | Self-assembly of virus-like particles of rabbit hemorrhagic disease virus capsid protein expressed in Escherichia coli and their immunogenicity in rabbits | |
| WO2011003100A4 (en) | Compositions and methods for diagnosing and/or treating influenza infection | |
| CN1223605C (zh) | 抑制sars冠状病毒的多肽药物及其衍生物和其应用 | |
| TW202016308A (zh) | 流感病毒血球凝集素突變體 | |
| WO2020092207A1 (en) | Broadly reactive immunogens of influenza virus, compositions, and methods of use thereof | |
| CN101879312B (zh) | 广谱型流感疫苗及其制备方法 | |
| TW201008576A (en) | New fusion proteins and their use for the preparation of vaccines against hepatitis C | |
| CN102397559A (zh) | 广谱型流感疫苗及其制备方法 | |
| Li et al. | Characterisation and haemagglutinin gene epitope mapping of a variant strain of H5N1 subtype avian influenza virus | |
| CA3221953A1 (en) | Broadly reactive viral antigens as immunogens, compositions and methods of use thereof |