JP2010506850A5 - - Google Patents
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- JP2010506850A5 JP2010506850A5 JP2009532577A JP2009532577A JP2010506850A5 JP 2010506850 A5 JP2010506850 A5 JP 2010506850A5 JP 2009532577 A JP2009532577 A JP 2009532577A JP 2009532577 A JP2009532577 A JP 2009532577A JP 2010506850 A5 JP2010506850 A5 JP 2010506850A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- formula
- yloxy
- pyrazol
- urea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85083406P | 2006-10-11 | 2006-10-11 | |
| US60/850,834 | 2006-10-11 | ||
| US11/870,388 US7790756B2 (en) | 2006-10-11 | 2007-10-10 | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases |
| US11/870,388 | 2007-10-10 | ||
| PCT/US2007/081098 WO2008046003A2 (en) | 2006-10-11 | 2007-10-11 | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012109422A Division JP5557872B2 (ja) | 2006-10-11 | 2012-05-11 | 慢性骨髄増殖疾患および他の増殖性疾患の治療のために有用なキナーゼ阻害剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010506850A JP2010506850A (ja) | 2010-03-04 |
| JP2010506850A5 true JP2010506850A5 (enExample) | 2011-02-17 |
| JP5042314B2 JP5042314B2 (ja) | 2012-10-03 |
Family
ID=39283624
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009532577A Active JP5042314B2 (ja) | 2006-10-11 | 2007-10-11 | 慢性骨髄増殖疾患および他の増殖性疾患の治療のために有用なキナーゼ阻害剤 |
| JP2012109422A Active JP5557872B2 (ja) | 2006-10-11 | 2012-05-11 | 慢性骨髄増殖疾患および他の増殖性疾患の治療のために有用なキナーゼ阻害剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012109422A Active JP5557872B2 (ja) | 2006-10-11 | 2012-05-11 | 慢性骨髄増殖疾患および他の増殖性疾患の治療のために有用なキナーゼ阻害剤 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7790756B2 (enExample) |
| EP (1) | EP2073811B1 (enExample) |
| JP (2) | JP5042314B2 (enExample) |
| KR (1) | KR101439823B1 (enExample) |
| CN (1) | CN101553233B (enExample) |
| AU (1) | AU2007307679B9 (enExample) |
| BR (2) | BR122020010667B8 (enExample) |
| CA (1) | CA2666563C (enExample) |
| DK (1) | DK2073811T3 (enExample) |
| ES (1) | ES2538215T3 (enExample) |
| IL (1) | IL197933A (enExample) |
| MX (1) | MX2009003704A (enExample) |
| PT (1) | PT2073811E (enExample) |
| RU (1) | RU2482112C2 (enExample) |
| SG (1) | SG175640A1 (enExample) |
| WO (1) | WO2008046003A2 (enExample) |
Families Citing this family (66)
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|---|---|---|---|---|
| JP5197016B2 (ja) | 2004-12-23 | 2013-05-15 | デシファラ ファーマスーティカルズ， エルエルシー | 酵素モジュレータ及び治療 |
| US8188113B2 (en) | 2006-09-14 | 2012-05-29 | Deciphera Pharmaceuticals, Inc. | Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases |
| US7790756B2 (en) | 2006-10-11 | 2010-09-07 | Deciphera Pharmaceuticals, Llc | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases |
| US20110189167A1 (en) * | 2007-04-20 | 2011-08-04 | Flynn Daniel L | Methods and Compositions for the Treatment of Myeloproliferative Diseases and other Proliferative Diseases |
| AU2008242720A1 (en) * | 2007-04-20 | 2008-10-30 | Deciphera Pharmaceuticals, Llc | Kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases |
| EP2365752B1 (en) * | 2008-10-29 | 2014-09-24 | Deciphera Pharmaceuticals, Llc | Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities |
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| US9340555B2 (en) | 2009-09-03 | 2016-05-17 | Allergan, Inc. | Compounds as tyrosine kinase modulators |
| NZ706154A (en) * | 2010-02-01 | 2016-09-30 | Cancer Rec Tech Ltd | 1-(5-tert-butyl-2-phenyl-2h-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1h-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy |
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| WO2014078325A1 (en) | 2012-11-13 | 2014-05-22 | Array Biopharma Inc. | N-(monocyclic aryl),n'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors |
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| EA202091763A1 (ru) | 2018-01-31 | 2020-12-14 | ДЕСИФЕРА ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Комбинированная терапия для лечения мастоцитоза |
| SG11202007198WA (en) | 2018-01-31 | 2020-08-28 | Deciphera Pharmaceuticals Llc | Combination therapy for the treatment of gastrointestinal stromal tumors |
| RS67303B1 (sr) | 2018-12-28 | 2025-11-28 | Deciphera Pharmaceuticals Llc | Inhibitori csf1r za upotrebu u lečenju tenosinovijalnih tumora džinovskih ćelija |
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| AU2020274011B2 (en) | 2019-05-10 | 2024-02-15 | Deciphera Pharmaceuticals, Llc | Heteroarylaminopyrimidine amide autophagy inhibitors and methods of use thereof |
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| US20230277522A9 (en) * | 2019-08-12 | 2023-09-07 | Deciphera Pharmaceuticals, Llc | Methods for treating vascular malformations |
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| JP7818502B2 (ja) | 2019-08-12 | 2026-02-20 | デシフェラ・ファーマシューティカルズ，エルエルシー | 胃腸間質腫瘍を治療するためのリプレチニブ |
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| EP4029501A1 (en) | 2021-01-19 | 2022-07-20 | Anagenesis Biotechnologies | Combination of polyaromatic urea derivatives and glucocorticoid or hdac inhibitor for the treatment of diseases or conditions associated with muscle cells and/or satellite cells |
| JP2024544632A (ja) | 2021-12-03 | 2024-12-03 | デシフェラ・ファーマシューティカルズ，エルエルシー | Ｇｃｎ２及びｐｅｒｋキナーゼ阻害剤としての複素環式化合物 |
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| US11779572B1 (en) | 2022-09-02 | 2023-10-10 | Deciphera Pharmaceuticals, Llc | Methods of treating gastrointestinal stromal tumors |
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| WO2025231106A1 (en) | 2024-05-01 | 2025-11-06 | Deciphera Pharmaceuticals, Llc | Csf-1r inhibitors and methods of use thereof |
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