JP2010501159A5 - - Google Patents

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JP2010501159A5
JP2010501159A5 JP2009522903A JP2009522903A JP2010501159A5 JP 2010501159 A5 JP2010501159 A5 JP 2010501159A5 JP 2009522903 A JP2009522903 A JP 2009522903A JP 2009522903 A JP2009522903 A JP 2009522903A JP 2010501159 A5 JP2010501159 A5 JP 2010501159A5
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JP
Japan
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stem cells
placental stem
cells
tumor
cell
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JP2009522903A
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Japanese (ja)
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JP5469457B2 (ja
JP2010501159A (ja
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Priority claimed from US11/888,926 external-priority patent/US7993918B2/en
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Publication of JP2010501159A5 publication Critical patent/JP2010501159A5/ja
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Publication of JP5469457B2 publication Critical patent/JP5469457B2/ja
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JP2009522903A 2006-08-04 2007-08-06 胎盤幹細胞を使用する腫瘍抑制 Expired - Fee Related JP5469457B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US83562706P 2006-08-04 2006-08-04
US60/835,627 2006-08-04
US11/888,926 US7993918B2 (en) 2006-08-04 2007-08-03 Tumor suppression using placental stem cells
US11/888,926 2007-08-03
PCT/US2007/017622 WO2008019148A2 (en) 2006-08-04 2007-08-06 Tumor suppression using placental stem cells

Publications (3)

Publication Number Publication Date
JP2010501159A JP2010501159A (ja) 2010-01-21
JP2010501159A5 true JP2010501159A5 (enExample) 2010-09-30
JP5469457B2 JP5469457B2 (ja) 2014-04-16

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JP2009522903A Expired - Fee Related JP5469457B2 (ja) 2006-08-04 2007-08-06 胎盤幹細胞を使用する腫瘍抑制

Country Status (13)

Country Link
US (2) US7993918B2 (enExample)
EP (2) EP2054508B1 (enExample)
JP (1) JP5469457B2 (enExample)
KR (1) KR101438554B1 (enExample)
CN (1) CN101720354A (enExample)
AU (1) AU2007281920B2 (enExample)
CA (1) CA2660014A1 (enExample)
ES (1) ES2432148T3 (enExample)
IL (2) IL196884A0 (enExample)
MX (1) MX2009001311A (enExample)
NZ (2) NZ574951A (enExample)
WO (1) WO2008019148A2 (enExample)
ZA (2) ZA200900956B (enExample)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8147824B2 (en) 1999-08-05 2012-04-03 Athersys, Inc. Immunomodulatory properties of multipotent adult progenitor cells and uses thereof
US7311905B2 (en) * 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
KR100915483B1 (ko) 2000-12-06 2009-09-03 로버트 제이 하리리 태반 줄기 세포의 회수 방법
AU2002251935B2 (en) * 2001-02-14 2007-11-29 Celularity Inc. Post-partum mammalian placenta, its use and placental stem cells therefrom
MX348185B (es) 2001-02-14 2017-06-02 Anthrogenesis Corp Placenta de mamíferos postparto, su uso y células madres placentales extraídas de ella.
US7498171B2 (en) * 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
BR0316695A (pt) * 2002-11-26 2005-10-18 Anthrogenesis Corp Unidade citoterapêutica, kit para tratamento, método de tratamento de uma enfermidade, biblioteca de unidades citoterapêuticas e método de tratamento de um paciente
NZ550027A (en) * 2004-03-26 2009-03-31 Celgene Corp Systems and methods for providing a stem cell bank
CA2624925C (en) * 2005-10-13 2014-09-30 Anthrogenesis Corporation Immunomodulation using placental stem cells
JP5203212B2 (ja) * 2005-10-13 2013-06-05 アントフロゲネシス コーポレーション 胎盤由来幹細胞からのオリゴデンドロサイトの産生
US10117900B2 (en) 2005-11-09 2018-11-06 Athersys, Inc. MAPC treatment of brain injuries and diseases
US11000546B2 (en) 2005-11-09 2021-05-11 Athersys, Inc. Immunomodulatory properties of MAPCs and uses thereof
US8067237B2 (en) 2005-12-13 2011-11-29 President And Fellows Of Harvard College Scaffolds for cell transplantation
PT2471904T (pt) 2005-12-29 2019-02-25 Celularity Inc População de células estaminais placentárias
KR20080097190A (ko) * 2005-12-29 2008-11-04 안트로제네시스 코포레이션 태반 줄기세포의 수집과 보존을 위한 개선된 조성물과 이조성물의 이용 방법
AU2006332679A1 (en) * 2005-12-29 2007-07-12 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
CA3028279C (en) 2006-01-23 2021-08-03 Athersys, Inc. Mapc therapeutics without adjunctive immunosuppressive treatment
US7993918B2 (en) 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
US8562972B2 (en) 2006-10-23 2013-10-22 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
CA2677397C (en) 2007-02-12 2016-04-05 Anthrogenesis Corporation Treatment of inflammatory diseases using placental stem cells
JP2010518812A (ja) * 2007-02-12 2010-06-03 アンスロジェネシス コーポレーション 接着性胎盤幹細胞由来の肝細胞および軟骨細胞、ならびにｃｄ３４＋、ｃｄ４５−胎盤幹細胞の濃縮細胞集団
EP2164953A4 (en) 2007-06-18 2010-06-30 Childrens Hosp & Res Ct Oak METHOD OF ISOLATING STAIN AND PRECIPITATING CELLS FROM PLAZENTA
US9770535B2 (en) * 2007-06-21 2017-09-26 President And Fellows Of Harvard College Scaffolds for cell collection or elimination
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
AU2008307633C1 (en) 2007-09-28 2015-04-30 Celularity Inc. Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
US9370558B2 (en) 2008-02-13 2016-06-21 President And Fellows Of Harvard College Controlled delivery of TLR agonists in structural polymeric devices
EP2254602B1 (en) 2008-02-13 2018-11-21 President and Fellows of Harvard College Continuous cell programming devices
RU2384618C2 (ru) * 2008-03-27 2010-03-20 Общество С Ограниченной Ответственностью "Лаборатория Клеточных Технологий" Способ получения фибробластоподобных клеток из пупочного канатика новорожденного
KR20200011604A (ko) 2008-08-20 2020-02-03 안트로제네시스 코포레이션 개선된 세포 조성물 및 그의 제조 방법
AU2009283217B2 (en) 2008-08-20 2015-09-17 Celularity Inc. Treatment of stroke using isolated placental cells
ES2552556T3 (es) 2008-08-22 2015-11-30 Anthrogenesis Corporation Métodos y composiciones para el tratamiento de defectos óseos con poblaciones de células placentarias
NZ592726A (en) 2008-11-19 2012-12-21 Anthrogenesis Corp Amnion derived adherent cells
CA2747794C (en) * 2008-12-19 2018-10-30 Advanced Technologies And Regenerative Medicine, Llc Treatment of lung and pulmonary diseases and disorders
US8771677B2 (en) 2008-12-29 2014-07-08 Vladimir B Serikov Colony-forming unit cell of human chorion and method to obtain and use thereof
CA2756594C (en) * 2009-03-25 2021-03-23 Anthrogenesis Corporation Treatment of viral infection using human placenta-derived intermediate natural killer cells and immunomodulatory compounds
NZ597436A (en) 2009-07-02 2014-08-29 Anthrogenesis Corp Method of producing erythrocytes without feeder cells
WO2011014871A1 (en) 2009-07-31 2011-02-03 President And Fellows Of Harvard College Programming of cells for tolerogenic therapies
EP2333047A1 (en) * 2009-12-09 2011-06-15 Fresenius Medical Care Deutschland GmbH Adult stem cell derived conditioned medium and/or adult stem cells for use in the therapeutic treatment of a tumor disease
JP2013518108A (ja) * 2010-01-26 2013-05-20 アントフロゲネシス コーポレーション 胎盤幹細胞を用いる骨関連癌の治療
LT2556145T (lt) 2010-04-07 2016-11-10 Anthrogenesis Corporation Angiogenezė naudojant placentos kamienines ląsteles
WO2011127113A1 (en) 2010-04-08 2011-10-13 Anthrogenesis Corporation Treatment of sarcoidosis using placental stem cells
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
CN101856496B (zh) * 2010-06-07 2013-09-18 四川大学 胎盘干细胞抗肿瘤疫苗及其制备方法与应用
NZ605505A (en) 2010-07-13 2015-02-27 Anthrogenesis Corp Methods of generating natural killer cells
CN101919378B (zh) * 2010-08-06 2013-09-11 青岛奥克生物开发有限公司 一种直接静脉应用的间充质干细胞冻存液
CA2813751C (en) 2010-10-06 2019-11-12 President And Fellows Of Harvard College Injectable, pore-forming hydrogels for materials-based cell therapies
US8574899B2 (en) 2010-12-22 2013-11-05 Vladimir B Serikov Methods for augmentation collection of placental hematopoietic stem cells and uses thereof
AR093183A1 (es) 2010-12-31 2015-05-27 Anthrogenesis Corp Aumento de la potencia de celulas madre de placenta usando moleculas de arn moduladoras
CN102210707B (zh) * 2011-04-01 2014-04-30 四川大学 协同刺激分子修饰胎盘成体干细胞活制剂及其制备与应用
US9675561B2 (en) 2011-04-28 2017-06-13 President And Fellows Of Harvard College Injectable cryogel vaccine devices and methods of use thereof
US10045947B2 (en) 2011-04-28 2018-08-14 President And Fellows Of Harvard College Injectable preformed macroscopic 3-dimensional scaffolds for minimally invasive administration
ES2707579T3 (es) 2011-06-01 2019-04-04 Celularity Inc Tratamiento del dolor usando citoblastos placentarios
EP2714073B1 (en) 2011-06-03 2021-03-10 President and Fellows of Harvard College In situ antigen-generating cancer vaccine
US9925221B2 (en) 2011-09-09 2018-03-27 Celularity, Inc. Treatment of amyotrophic lateral sclerosis using placental stem cells
CN107137357B (zh) 2012-04-16 2020-11-24 哈佛学院董事会 用于调节免疫反应的介孔二氧化硅组合物
ITTO20120859A1 (it) * 2012-10-02 2014-04-03 Univ Degli Studi Torino Nuova applicazione terapeutica di un mezzo condizionato da cellule staminali mesenchimali placentari
CN115282165A (zh) 2013-02-05 2022-11-04 细胞结构公司 来自胎盘的自然杀伤细胞
JP6235795B2 (ja) * 2013-05-29 2017-11-22 国立大学法人 東京医科歯科大学 細胞のリプログラミングのための組成物
CN103331374A (zh) * 2013-06-13 2013-10-02 南京惠德机械有限公司 一种线材成型快换模
EP3038630B1 (en) * 2013-08-30 2020-03-18 MIMEDX Group Inc. Micronized placental compositions comprising a chelator
US10682400B2 (en) 2014-04-30 2020-06-16 President And Fellows Of Harvard College Combination vaccine devices and methods of killing cancer cells
CN105316283B (zh) * 2014-08-01 2019-02-12 深圳华大基因科技有限公司 一种临床级胎盘间充质干细胞制备方法
CN104212761A (zh) * 2014-08-20 2014-12-17 北京瑞思德生物科技有限公司 用于制备胎盘干细胞的试剂盒
WO2016123573A1 (en) 2015-01-30 2016-08-04 President And Fellows Of Harvard College Peritumoral and intratumoral materials for cancer therapy
ES2861381T3 (es) * 2015-03-06 2021-10-06 Univ Ajou Ind Academic Coop Found Agente terapéutico celular para el tratamiento del cáncer y politerapia con el mismo
CN107864627A (zh) * 2015-03-23 2018-03-30 普拉里斯坦有限公司 包含粘附基质细胞的方法和组合物
EP3280464A4 (en) 2015-04-10 2018-09-26 President and Fellows of Harvard College Immune cell trapping devices and methods for making and using the same
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
CN115487351A (zh) 2016-02-06 2022-12-20 哈佛学院校长同事会 重塑造血巢以重建免疫
WO2017141181A1 (en) * 2016-02-18 2017-08-24 Pluristem Ltd. Methods and compositions for treating cancers and neoplasms
WO2017156341A1 (en) 2016-03-09 2017-09-14 Beijing Percans Oncology Co. Ltd. Tumor cell suspension cultures and related methods
DK3484448T3 (da) 2016-07-13 2025-06-10 Harvard College Antigenpræsenterende cellemimetiske stilladser og fremgangsmåder til fremstilling og brug af disse
JP7274214B2 (ja) 2016-08-02 2023-05-16 プレジデント アンド フェローズ オブ ハーバード カレッジ 免疫応答を調節するための生体材料
JP7076126B2 (ja) * 2016-10-11 2022-05-27 国立大学法人富山大学 羊膜間葉系幹細胞の抗腫瘍薬としての使用
CN110462028A (zh) * 2016-11-21 2019-11-15 北京智康博药肿瘤医学研究有限公司 上皮肿瘤细胞培养物
SG10202111394XA (en) 2017-04-13 2021-12-30 Senti Biosciences Inc Combinatorial cancer immunotherapy
CN108904799A (zh) * 2018-07-09 2018-11-30 夏荣木 一种抗肿瘤制剂及制备的方法
WO2020061129A1 (en) 2018-09-19 2020-03-26 President And Fellows Of Harvard College Compositions and methods for labeling and modulation of cells in vitro and in vivo
EP3866813A4 (en) 2018-10-17 2022-08-03 Senti Biosciences, Inc. COMBINATORY CANCER IMMUNOTHERAPY
US11419898B2 (en) 2018-10-17 2022-08-23 Senti Biosciences, Inc. Combinatorial cancer immunotherapy
WO2021071127A1 (ko) * 2019-10-11 2021-04-15 경북대학교 산학협력단 엑소좀 pd-l1의 발현에 대한 억제제를 유효성분으로 포함하는 항암 효과 증진용 조성물

Family Cites Families (140)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US396397A (en) * 1889-01-22 Revolving mold-board for plows
US24280A (en) * 1859-06-07 Machine for bubring wool and ginning cotton
US104164A (en) * 1870-06-14 Hubert l
US136471A (en) * 1873-03-04 Improvement in ironing apparatus
US53805A (en) * 1866-04-10 Improved amalgamator
US240956A (en) * 1881-05-03 Magnet for separating iron chips
US213228A (en) * 1879-03-11 Improvement in grates
US175824A (en) * 1876-04-11 Improvement in sleighs
US226595A (en) * 1880-04-20 Eichabd f
US206343A (en) * 1878-07-23 Improvement in embalming compositions
US5004681B1 (en) * 1987-11-12 2000-04-11 Biocyte Corp Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood
US5192553A (en) * 1987-11-12 1993-03-09 Biocyte Corporation Isolation and preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood and methods of therapeutic use
GB8803697D0 (en) 1988-02-17 1988-03-16 Deltanine Research Ltd Clinical developments using amniotic membrane cells
US5733542A (en) * 1990-11-16 1998-03-31 Haynesworth; Stephen E. Enhancing bone marrow engraftment using MSCS
US5486359A (en) * 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US6010696A (en) * 1990-11-16 2000-01-04 Osiris Therapeutics, Inc. Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells
US5837539A (en) * 1990-11-16 1998-11-17 Osiris Therapeutics, Inc. Monoclonal antibodies for human mesenchymal stem cells
US5750376A (en) * 1991-07-08 1998-05-12 Neurospheres Holdings Ltd. In vitro growth and proliferation of genetically modified multipotent neural stem cells and their progeny
EP0627003A1 (en) * 1991-12-23 1994-12-07 British Bio-Technology Limited Stem cell inhibiting proteins
US5426098A (en) * 1993-09-02 1995-06-20 Celtrix Pharmaceuticals, Inc. Increase in hematopoietic progenitor cells in peripheral blood by transforming growth factor beta
US5591625A (en) * 1993-11-24 1997-01-07 Case Western Reserve University Transduced mesenchymal stem cells
US6174333B1 (en) * 1994-06-06 2001-01-16 Osiris Therapeutics, Inc. Biomatrix for soft tissue regeneration using mesenchymal stem cells
EP0952792B1 (en) * 1994-06-06 2003-08-27 Case Western Reserve University Biomatrix for tissue regeneration
US5736396A (en) * 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
WO1997018298A1 (en) * 1995-11-14 1997-05-22 Regents Of The University Of Minnesota Ex vivo culture of stem cells
ES2329953T3 (es) * 1996-04-19 2009-12-02 Osiris Therapeutics, Inc. Regeneracion e incremento de hueso utilizando celulas madre mesenquimales.
US5827740A (en) 1996-07-30 1998-10-27 Osiris Therapeutics, Inc. Adipogenic differentiation of human mesenchymal stem cells
US5916202A (en) * 1996-08-30 1999-06-29 Haswell; John N. Umbilical cord blood collection
US5945337A (en) * 1996-10-18 1999-08-31 Quality Biological, Inc. Method for culturing CD34+ cells in a serum-free medium
US6387369B1 (en) * 1997-07-14 2002-05-14 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
US7514074B2 (en) * 1997-07-14 2009-04-07 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
AU9127098A (en) * 1997-09-04 1999-03-22 Osiris Therapeutics, Inc. Ligands that modulate differentiation of mesenchymal stem cells
BR9907852A (pt) 1998-02-12 2000-10-24 Immunivest Corp Processos para detectar e enumerar células raras e cancerosas em uma população celular mista, para diagnosticar câncer de estágio precoce em um paciente de teste, para determinar a probabilidade de recorrência de câncer em um paciente humano anteriormente tratado de câncer, para distinguir um carcinoma confinado ao órgão de um carcinoma com propriedades metastáticas, para acompanhar a situação de remissão em um paciente humano com câncer que passa pelo tratamento de terapia contra o câncer e para aumentar quantidades de células epiteliais circulantes em uma amostra de sangue, partìcula magnética revestida, composição, conjuntos de teste para avaliar uma amostra de paciente quanto a presença de células raras circulantes, quanto a presença de células de tumor circulantes, quanto a presença de células de câncer de mama circulantes, quanto a presença de células de câncer de próstata circulantes, quanto a presença de células de câncer de cólon circulantes, quanto a presença de células de câncer de bexiga circulantes e para monitorar um paciente quanto a recorrência de câncer, e, fração de sangue periférico enriquecido quanto a células neoplásticas circulantes
EP1062321B1 (en) * 1998-03-13 2004-12-29 Osiris Therapeutics, Inc. Uses for humane non-autologous mesenchymal stem cells
ES2258329T3 (es) 1998-03-18 2006-08-16 Osiris Therapeutics, Inc. Celulas madre mesenquimaticas para la prevencion y tratamiento de respuestas inmunes en trasplantes.
US6368636B1 (en) * 1998-03-18 2002-04-09 Osiris Therapeutics, Inc. Mesenchymal stem cells for prevention and treatment of immune responses in transplantation
DK1066060T3 (da) 1998-04-03 2003-11-24 Osiris Therapeutics Inc Mesenkymale stamceller som immunsuppresive midler
US6835377B2 (en) 1998-05-13 2004-12-28 Osiris Therapeutics, Inc. Osteoarthritis cartilage regeneration
US6225119B1 (en) 1998-05-22 2001-05-01 Osiris Therapeutics, Inc. Production of megakaryocytes by the use of human mesenchymal stem cells
DK1082410T3 (da) * 1998-05-29 2007-11-26 Osiris Therapeutics Inc Humane CD45 - og/eller fibroblast mesenchymale stamceller
CA2680649A1 (en) * 1998-06-08 1999-12-16 Osiris Therapeutics, Inc. Regulation of hematopoietic stem cell differentiation by the use of human mesenchymal stem cells
DE69937966D1 (de) 1998-11-12 2008-02-21 Cytomatrix Llc Produktion lymphoider gewebsspezifischer zellen von hämatopoietischen vorläuferzellen in einem dreidimensionalen system
US6328765B1 (en) 1998-12-03 2001-12-11 Gore Enterprise Holdings, Inc. Methods and articles for regenerating living tissue
US8147824B2 (en) 1999-08-05 2012-04-03 Athersys, Inc. Immunomodulatory properties of multipotent adult progenitor cells and uses thereof
US7015037B1 (en) 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
US6685936B2 (en) * 1999-10-12 2004-02-03 Osiris Therapeutics, Inc. Suppressor cells induced by culture with mesenchymal stem cells for treatment of immune responses in transplantation
DE19954421A1 (de) 1999-11-12 2001-05-31 Lohmann Therapie Syst Lts Filmförmige Zubereitung zur biphasigen Freisetzung pharmakologisch wirksamer oder anderer Substanzen
MXPA02006778A (es) * 2000-01-12 2004-04-05 Ventana Inc Metodo para determinar la respuesta a una terapia de cancer.
US20010038836A1 (en) 2000-04-04 2001-11-08 Matthew During Application of myeloid-origin cells to the nervous system
DE10021977A1 (de) * 2000-05-05 2001-11-08 Meto International Gmbh Radiofrequenz (RF) - Sicherungselement, Spule und Kondensator für ein RF-Sicherungselement und Verfahren zu deren Herstellung
KR100915483B1 (ko) 2000-12-06 2009-09-03 로버트 제이 하리리 태반 줄기 세포의 회수 방법
US20080152629A1 (en) * 2000-12-06 2008-06-26 James Edinger Placental stem cell populations
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
US7091353B2 (en) 2000-12-27 2006-08-15 Celgene Corporation Isoindole-imide compounds, compositions, and uses thereof
US20030045552A1 (en) 2000-12-27 2003-03-06 Robarge Michael J. Isoindole-imide compounds, compositions, and uses thereof
MX348185B (es) 2001-02-14 2017-06-02 Anthrogenesis Corp Placenta de mamíferos postparto, su uso y células madres placentales extraídas de ella.
CA2438501C (en) 2001-02-14 2014-09-16 Leo T. Furcht Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
AU2002251935B2 (en) * 2001-02-14 2007-11-29 Celularity Inc. Post-partum mammalian placenta, its use and placental stem cells therefrom
US20030044977A1 (en) * 2001-08-10 2003-03-06 Norio Sakuragawa Human stem cells originated from human amniotic mesenchymal cell layer
DE10139783C1 (de) 2001-08-14 2003-04-17 Transtissue Technologies Gmbh Zellzusammensetzungen zur Behandlung von Osteoarthrose, sowie Verfahren zu deren Herstellung
US20030044976A1 (en) * 2001-08-27 2003-03-06 Advanced Cell Technology De-differentiation and re-differentiation of somatic cells and production of cells for cell therapies
US9969980B2 (en) 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
DE60233248D1 (de) * 2001-11-15 2009-09-17 Childrens Medical Center Verfahren zur isolierung, expansion und differenzierung fötaler stammzellen aus chorionzotte, fruchtwasser und plazenta und therapeutische verwendungen davon
US7799324B2 (en) 2001-12-07 2010-09-21 Geron Corporation Using undifferentiated embryonic stem cells to control the immune system
JP3934539B2 (ja) 2001-12-12 2007-06-20 独立行政法人科学技術振興機構 胎盤等由来の成体又は生後組織の前駆細胞
US20040018178A1 (en) 2002-01-22 2004-01-29 Advanced Cell Technology Stem cell-derived endothelial cells modified to disrupt tumor angiogenesis
US20030161818A1 (en) * 2002-02-25 2003-08-28 Kansas State University Research Foundation Cultures, products and methods using stem cells
US7736892B2 (en) * 2002-02-25 2010-06-15 Kansas State University Research Foundation Cultures, products and methods using umbilical cord matrix cells
US20030187515A1 (en) 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
WO2003086373A1 (en) * 2002-04-12 2003-10-23 Celgene Corporation Methods for identification of modulators of angiogenesis, compounds discovered thereby, and methods of treatment using the compounds
US20050118715A1 (en) * 2002-04-12 2005-06-02 Hariri Robert J. Modulation of stem and progenitor cell differentiation, assays, and uses thereof
US7498171B2 (en) * 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
US20040161419A1 (en) * 2002-04-19 2004-08-19 Strom Stephen C. Placental stem cells and uses thereof
US20030235563A1 (en) 2002-04-19 2003-12-25 Strom Stephen C. Placental derived stem cells and uses thereof
CA2488013A1 (en) * 2002-05-30 2003-12-11 Celgene Corporation Methods of using jnk or mkk inhibitors to modulate cell differentiation and to treat myeloproliferative disorders and myelodysplastic syndromes
US7422736B2 (en) * 2002-07-26 2008-09-09 Food Industry Research And Development Institute Somatic pluripotent cells
JP4603883B2 (ja) 2002-07-31 2010-12-22 サントル・ナショナル・ドゥ・ラ・レシェルシュ・サイエンティフィーク−セ・エン・エール・エス− 脂肪組織由来の幹細胞および前記細胞から分化した細胞
BR0316695A (pt) 2002-11-26 2005-10-18 Anthrogenesis Corp Unidade citoterapêutica, kit para tratamento, método de tratamento de uma enfermidade, biblioteca de unidades citoterapêuticas e método de tratamento de um paciente
ES2351386T3 (es) * 2003-02-11 2011-02-03 John E. Davies Células progenitoras procedentes de la gelatina de wharton de cordón umbilical humano .
MXPA05008445A (es) * 2003-02-13 2005-10-18 Anthrogenesis Corp Uso de sangre del cordon umbilical para tratar individuos que tienen una enfermedad, un trastorno o una afeccion.
CN1548529A (zh) 2003-05-09 2004-11-24 中国人民解放军军事医学科学院基础医 一种人胎盘间充质干细胞的分离方法
US7875272B2 (en) 2003-06-27 2011-01-25 Ethicon, Incorporated Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells
JP4948166B2 (ja) * 2003-06-27 2012-06-06 エチコン、インコーポレイテッド 分娩後由来細胞を用いた軟骨と骨の修復と再生
US20050042595A1 (en) * 2003-08-14 2005-02-24 Martin Haas Banking of multipotent amniotic fetal stem cells
US20050089513A1 (en) 2003-10-28 2005-04-28 Norio Sakuragawa Side population cells originated from human amnion and their uses
EP1682654A2 (en) 2003-11-10 2006-07-26 Amgen Inc. Methods of using g-csf mobilized c-kit+cells in the production of embryoid body-like cell clusters for tissue repair and in the treatment of cardiac myopathy
JP2005151907A (ja) 2003-11-27 2005-06-16 Shigeo Saito 胎盤又は羊膜由来ヒト幹細胞及びその樹立方法並びに臓器への分化誘導方法
US20050143420A1 (en) * 2003-12-02 2005-06-30 Moutouh-De Parseval Laure Methods and compositions for the treatment and management of hemoglobinopathy and anemia
US20050176139A1 (en) 2004-01-12 2005-08-11 Yao-Chang Chen Placental stem cell and methods thereof
US20050266391A1 (en) 2004-01-15 2005-12-01 Bennett Brydon L Methods for preserving tissue
EP2298863B1 (en) 2004-03-22 2015-07-22 Mesoblast International Sàrl Mesenchymal stem cells and uses therefor
NZ550027A (en) 2004-03-26 2009-03-31 Celgene Corp Systems and methods for providing a stem cell bank
JP2006006249A (ja) 2004-06-28 2006-01-12 Hiroshima Univ 羊膜由来細胞の培養方法及びその利用
US7244759B2 (en) 2004-07-28 2007-07-17 Celgene Corporation Isoindoline compounds and methods of making and using the same
BRPI0514387B8 (pt) * 2004-08-16 2021-05-25 Cellresearch Corp Pte Ltd método para isolar células-tronco epiteliais ou mesenquimais/progenitoras da membrana amniótica do cordão umbilical, método in vitro para cultivar células-tronco mesenquimais/progenitoras, composição farmacêutica e uso de uma célula-tronco epitelial ou mesenquimal/progenitora
US7909806B2 (en) 2004-09-23 2011-03-22 Anthrogenesis Corporation Cord blood and placenta collection kit
US7147626B2 (en) 2004-09-23 2006-12-12 Celgene Corporation Cord blood and placenta collection kit
US20060171930A1 (en) 2004-12-21 2006-08-03 Agnieszka Seyda Postpartum cells derived from umbilical cord tissue, and methods of making, culturing, and using the same
US20060166361A1 (en) * 2004-12-21 2006-07-27 Agnieszka Seyda Postpartum cells derived from placental tissue, and methods of making, culturing, and using the same
PT1835924E (pt) 2004-12-23 2013-11-19 Ethicon Inc Tratamento da doença de parkinson e desordens relacionadas usando células derivadas do pós-parto
EP1831356B1 (en) 2004-12-23 2017-01-25 DePuy Synthes Products, Inc. Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
WO2006074308A2 (en) * 2005-01-07 2006-07-13 Wake Forest University Health Sciences Regeneration of pancreatic islets by amniotic fluid stem cell therapy
US20060222634A1 (en) 2005-03-31 2006-10-05 Clarke Diana L Amnion-derived cell compositions, methods of making and uses thereof
AU2006202209B2 (en) * 2005-05-27 2011-04-14 Lifescan, Inc. Amniotic fluid derived cells
NZ564563A (en) 2005-06-10 2011-03-31 Celgene Corp Human placental collagen compositions, processes for their preparation, methods of their use and kits comprising the compositions
CN101252957A (zh) 2005-06-30 2008-08-27 人类起源公司 使用胎盘源胶原生物纤维的鼓膜修复
US20070021762A1 (en) 2005-07-13 2007-01-25 Qing Liu Ocular plug formed from placenta derived collagen biofabric
EP1919500A2 (en) 2005-07-13 2008-05-14 Anthrogenesis Corporation Treatment of leg ulcers using placenta derived collagen biofabric
WO2007011693A2 (en) * 2005-07-14 2007-01-25 Medistem Laboratories, Inc. Compositions of placentally-derived stem cells for the treatment of cancer
JP5203212B2 (ja) * 2005-10-13 2013-06-05 アントフロゲネシス コーポレーション 胎盤由来幹細胞からのオリゴデンドロサイトの産生
CA2624925C (en) * 2005-10-13 2014-09-30 Anthrogenesis Corporation Immunomodulation using placental stem cells
CN101374946B (zh) 2005-12-16 2017-07-18 伊西康公司 用于在组织相容性不匹配的移植中抑制有害的免疫反应的组合物和方法
EP1979050B1 (en) * 2005-12-28 2017-04-19 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using postpartum-derived cells
KR20080097190A (ko) 2005-12-29 2008-11-04 안트로제네시스 코포레이션 태반 줄기세포의 수집과 보존을 위한 개선된 조성물과 이조성물의 이용 방법
PT2471904T (pt) * 2005-12-29 2019-02-25 Celularity Inc População de células estaminais placentárias
AU2006332679A1 (en) * 2005-12-29 2007-07-12 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
US20070253931A1 (en) 2006-01-12 2007-11-01 Osiris Therapeutics, Inc. Use of mesenchymal stem cells for treating genetic diseases and disorders
US9944900B2 (en) 2006-01-18 2018-04-17 Hemacell Perfusion Pulsatile perfusion extraction method for non-embryonic pluripotent stem cells
EP1845154A1 (en) 2006-04-12 2007-10-17 RNL Bio Co., Ltd. Multipotent stem cells derived from placenta tissue and cellular therapeutic agents comprising the same
CA2654716A1 (en) 2006-06-09 2007-12-21 Anthrogenesis Corporation Placental niche and use thereof to culture stem cells
US20070287176A1 (en) 2006-06-13 2007-12-13 Alireza Rezania Chorionic villus derived cells
US7993918B2 (en) 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
WO2008021391A1 (en) 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
US8122763B2 (en) * 2006-09-01 2012-02-28 Avair, Llc Breathing gas supply visual broadcast apparatus
US20080131522A1 (en) 2006-10-03 2008-06-05 Qing Liu Use of placental biomaterial for ocular surgery
WO2008060377A2 (en) 2006-10-04 2008-05-22 Anthrogenesis Corporation Placental or umbilical cord tissue compositions
NZ612094A (en) 2006-10-06 2015-02-27 Anthrogenesis Corp Native (telopeptide) placental collagen compositions
US8562972B2 (en) 2006-10-23 2013-10-22 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
JP2010518812A (ja) 2007-02-12 2010-06-03 アンスロジェネシス コーポレーション 接着性胎盤幹細胞由来の肝細胞および軟骨細胞、ならびにｃｄ３４＋、ｃｄ４５−胎盤幹細胞の濃縮細胞集団
CA2677397C (en) 2007-02-12 2016-04-05 Anthrogenesis Corporation Treatment of inflammatory diseases using placental stem cells
KR20160092062A (ko) 2007-09-26 2016-08-03 안트로제네시스 코포레이션 인간 태반 관류액으로부터의 혈관형성 세포
AU2008307633C1 (en) 2007-09-28 2015-04-30 Celularity Inc. Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
US20090136471A1 (en) 2007-11-07 2009-05-28 Anthrogenesis Corporation Treatment of premature birth complications
JP2011524421A (ja) * 2008-06-16 2011-09-01 イミュノジェン・インコーポレーテッド 新規の相乗効果
AU2009283217B2 (en) * 2008-08-20 2015-09-17 Celularity Inc. Treatment of stroke using isolated placental cells
KR20200011604A (ko) * 2008-08-20 2020-02-03 안트로제네시스 코포레이션 개선된 세포 조성물 및 그의 제조 방법
ES2552556T3 (es) * 2008-08-22 2015-11-30 Anthrogenesis Corporation Métodos y composiciones para el tratamiento de defectos óseos con poblaciones de células placentarias
NZ592726A (en) * 2008-11-19 2012-12-21 Anthrogenesis Corp Amnion derived adherent cells
ES2731340T3 (es) * 2008-11-21 2019-11-15 Celularity Inc Tratamiento de enfermedades, trastornos o afecciones pulmonares utilizando células placentarias
NZ597436A (en) * 2009-07-02 2014-08-29 Anthrogenesis Corp Method of producing erythrocytes without feeder cells

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