JP2010259446A5 - - Google Patents
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- Publication number
- JP2010259446A5 JP2010259446A5 JP2010176512A JP2010176512A JP2010259446A5 JP 2010259446 A5 JP2010259446 A5 JP 2010259446A5 JP 2010176512 A JP2010176512 A JP 2010176512A JP 2010176512 A JP2010176512 A JP 2010176512A JP 2010259446 A5 JP2010259446 A5 JP 2010259446A5
- Authority
- JP
- Japan
- Prior art keywords
- poxvirus
- gene
- recombinant poxvirus
- recombinant
- homologous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200200752 | 2002-05-16 | ||
| DKPA200200753 | 2002-05-16 | ||
| DKPA200200753 | 2002-05-16 | ||
| DKPA200200752 | 2002-05-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004506501A Division JP4693092B2 (ja) | 2002-05-16 | 2003-05-14 | ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2010259446A JP2010259446A (ja) | 2010-11-18 |
| JP2010259446A5 true JP2010259446A5 (https=) | 2011-07-28 |
| JP5777199B2 JP5777199B2 (ja) | 2015-09-09 |
Family
ID=29551228
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004506500A Expired - Lifetime JP4895505B2 (ja) | 2002-05-16 | 2003-05-14 | 変異ワクシニアウイルスアンカラ(mva)ゲノム中の挿入部位としての遺伝子間領域 |
| JP2004506501A Expired - Lifetime JP4693092B2 (ja) | 2002-05-16 | 2003-05-14 | ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス |
| JP2010176511A Pending JP2011004755A (ja) | 2002-05-16 | 2010-08-05 | ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス |
| JP2010176512A Expired - Lifetime JP5777199B2 (ja) | 2002-05-16 | 2010-08-05 | ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004506500A Expired - Lifetime JP4895505B2 (ja) | 2002-05-16 | 2003-05-14 | 変異ワクシニアウイルスアンカラ(mva)ゲノム中の挿入部位としての遺伝子間領域 |
| JP2004506501A Expired - Lifetime JP4693092B2 (ja) | 2002-05-16 | 2003-05-14 | ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス |
| JP2010176511A Pending JP2011004755A (ja) | 2002-05-16 | 2010-08-05 | ポックスウイルスゲノムに挿入された相同遺伝子を発現させる組換えポックスウイルス |
Country Status (22)
| Country | Link |
|---|---|
| US (14) | US7338662B2 (https=) |
| EP (3) | EP2253709B1 (https=) |
| JP (4) | JP4895505B2 (https=) |
| KR (4) | KR20120002627A (https=) |
| CN (6) | CN102703393A (https=) |
| AT (1) | ATE315660T1 (https=) |
| AU (4) | AU2003236646B2 (https=) |
| BR (2) | BRPI0311178B8 (https=) |
| CA (3) | CA2812019A1 (https=) |
| DE (1) | DE60303218T2 (https=) |
| DK (2) | DK1407033T3 (https=) |
| EA (3) | EA012160B1 (https=) |
| ES (1) | ES2256776T3 (https=) |
| IL (4) | IL164177A0 (https=) |
| MX (2) | MXPA04011194A (https=) |
| NO (3) | NO334273B1 (https=) |
| NZ (2) | NZ536501A (https=) |
| PL (2) | PL218318B1 (https=) |
| PT (1) | PT1407033E (https=) |
| SI (1) | SI1407033T1 (https=) |
| UA (1) | UA82479C2 (https=) |
| WO (2) | WO2003097846A1 (https=) |
Families Citing this family (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4101327C1 (https=) * | 1991-01-18 | 1991-10-24 | Mercedes-Benz Aktiengesellschaft, 7000 Stuttgart, De | |
| PL212047B1 (pl) * | 2000-11-23 | 2012-08-31 | Bavarian Nordic As | Zmodyfikowany wirus krowianki szczepu Ankara MVA-BN i jego pochodna, genom i zawierające je kompozycja farmaceutyczna, zwłaszcza szczepionka oraz ich zastosowania |
| NZ536592A (en) * | 2002-04-19 | 2007-01-26 | Bavarian Nordic As | Modified vaccinia virus ankara for the vaccination of neonates |
| US7501127B2 (en) | 2002-05-16 | 2009-03-10 | Bavarian Nordic A/S | Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara |
| CN102703393A (zh) | 2002-05-16 | 2012-10-03 | 巴法里安诺迪克有限公司 | 表达插入痘病毒基因组中的同源基因的重组痘病毒 |
| JP2005537793A (ja) * | 2002-09-05 | 2005-12-15 | バヴァリアン・ノルディック・アクティーゼルスカブ | 無血清条件下で初代細胞を培養する方法及びウイルスを増幅させる方法 |
| EP1601333B1 (en) * | 2003-02-20 | 2013-01-23 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services | Novel insertion sites in pox vectors |
| GB2402391A (en) * | 2003-06-04 | 2004-12-08 | Oxxon Pharmaccines Ltd | Fowlpox recombinant genome |
| WO2006052826A2 (en) * | 2004-11-05 | 2006-05-18 | The Government Of The United States Of America As Represented By The Secretary | Methods for preparing cells and viruses |
| AU2006218115B2 (en) * | 2005-02-23 | 2012-08-02 | Bavarian Nordic A/S | Use of a modified poxvirus for the rapid induction of immunity against a poxvirus or other infectious agents |
| CA2651456A1 (en) * | 2006-05-19 | 2007-11-29 | Glycofi, Inc. | Recombinant vectors |
| DK2062023T4 (en) | 2006-08-25 | 2017-02-20 | The Government Of The Us Secretary Dept Of Health And Human Services | INTERGENIC SITES BETWEEN CONSERVATED GENES THROUGH MODIFIED VACCINIA ANKARA (VAT) VACCINIAVIRUS |
| EP2426142A3 (en) | 2006-10-16 | 2012-06-13 | Genelux Corporation | Modified vaccinia virus strains for use in a diagnostic and therapeutic method |
| ES2517615T3 (es) * | 2006-11-09 | 2014-11-03 | The United States Of America As Represented By The Secretary Of The Navy | Inducción de una respuesta inmunitaria frente al virus del dengue usando un enfoque de sensibilización-refuerzo |
| US8440202B2 (en) * | 2006-11-09 | 2013-05-14 | The United States Of America As Represented By The Secretary Of The Navy | Induction of an immune response against dengue virus using the prime-boost approach |
| WO2008092854A2 (en) * | 2007-01-30 | 2008-08-07 | Transgene S.A. | Papillomavirus e2 polypeptide used for vaccination |
| US8268327B2 (en) | 2007-04-27 | 2012-09-18 | Bavarian Nordic A/S | Immediate protection against pathogens via MVA |
| JP5474767B2 (ja) * | 2007-05-15 | 2014-04-16 | トランジェーヌ、ソシエテ、アノニム | 多重遺伝子発現のためのベクター |
| TW200907058A (en) * | 2007-05-30 | 2009-02-16 | Wyeth Corp | Raccoon poxvirus expressing rabies glycoproteins |
| EP2155883A1 (en) * | 2007-05-30 | 2010-02-24 | Wyeth LLC | Raccoon poxvirus expressing genes of feline antigens |
| NZ601827A (en) | 2007-10-18 | 2014-01-31 | Bavarian Nordic Inc | Use of mva to treat prostate cancer |
| WO2009152969A1 (en) * | 2008-06-20 | 2009-12-23 | Bavarian Nordic A/S | Recombinant modified vaccinia virus measles vaccine |
| KR100894430B1 (ko) * | 2008-11-11 | 2009-04-22 | 시스템디엔디(주) | 초음파, 음향 및 온도변화를 이용한 밸브의 유체누설 측정장치 및 이를 이용한 유체누설 측정방법 |
| CN102325888B (zh) * | 2008-11-21 | 2016-09-07 | 巴法里安诺迪克有限公司 | 包含多个同源核苷酸序列的载体 |
| US8580276B2 (en) | 2009-06-05 | 2013-11-12 | City Of Hope | Genetically stable recombinant modified vaccinia ankara (rMVA) vaccines and methods of preparation thereof |
| CA2767924A1 (en) | 2009-10-08 | 2011-04-14 | Bavarian Nordic A/S | Generation of a broad t-cell response in humans against hiv |
| WO2011047324A1 (en) | 2009-10-16 | 2011-04-21 | The U.S.A. As Represented By The Secretary , Department Of Health And Human Services . | Recombinant modified vaccinia ankara (mva) vaccinia virus containing restructured insertion sites |
| WO2011087839A1 (en) | 2009-12-22 | 2011-07-21 | Baxter International Inc. | Vaccine to influenza a virus |
| EP2552490A4 (en) * | 2010-03-26 | 2013-12-18 | Emergent Product Dev Gaithersburg Inc | INFLUENZA MATRIX 2 PROTEIN ECKTOMOMAS, EXPRESSION SYSTEM THEREFOR AND USES THEREOF |
| AU2011281982B2 (en) | 2010-07-20 | 2015-12-17 | Bavarian Nordic A/S | Method for harvesting expression products |
| WO2012040474A2 (en) * | 2010-09-23 | 2012-03-29 | Baxter International Inc. | Recombinant viral vectors and methods for inducing an immune response to yellow fever virus |
| WO2012048817A2 (en) | 2010-10-15 | 2012-04-19 | Bavarian Nordic A/S | Recombinant modified vaccinia virus ankara influenza vaccine |
| CN114262690A (zh) | 2011-04-15 | 2022-04-01 | 吉恩勒克斯公司 | 减毒的痘苗病毒的克隆毒株及其使用方法 |
| DK2788021T3 (en) | 2011-12-09 | 2017-04-10 | Bavarian Nordic As | POXVIRUS VECTOR FOR EXPRESSION OF BACTERIAL ANTIGENES CONNECTED TO TETANANOX INFRAGMENT C |
| EP2620446A1 (en) | 2012-01-27 | 2013-07-31 | Laboratorios Del Dr. Esteve, S.A. | Immunogens for HIV vaccination |
| WO2013181696A1 (en) | 2012-06-05 | 2013-12-12 | The Australian National University | Vaccination with interleukin-4 antagonists |
| MY171498A (en) | 2012-08-01 | 2019-10-15 | Bavarian Nordic As | Recombinant modified vaccinia virus ankara (mva) respiratory syncytial virus (rsv) vaccine |
| WO2014043535A1 (en) | 2012-09-14 | 2014-03-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compositions for the treatment of cancer |
| US20140140959A1 (en) | 2012-10-05 | 2014-05-22 | Aladar A. Szalay | Energy Absorbing-Based Diagnostic and Therapeutic Methods Employing Nucleic Acid Molecules Encoding Chromophore-Producing Enzymes |
| US20150283220A1 (en) | 2012-10-19 | 2015-10-08 | Bavarian Nordic, Inc. | Methods and compositions for the treatment of cancer |
| WO2014139587A1 (en) * | 2013-03-15 | 2014-09-18 | Okairòs Ag | Improved poxviral vaccines |
| DE102013004595A1 (de) | 2013-03-15 | 2014-09-18 | Emergent Product Development Germany Gmbh | RSV-Impfstoffe |
| NZ630642A (en) * | 2013-03-15 | 2016-01-29 | Sementis Ltd | Immune modulation |
| WO2015103438A2 (en) | 2014-01-02 | 2015-07-09 | Genelux Corporation | Oncolytic virus adjunct therapy with agents that increase virus infectivity |
| KR101645642B1 (ko) | 2014-10-16 | 2016-08-11 | 대한민국 | Kvac103 유래의 재조합 백시니아 바이러스 |
| KR101623498B1 (ko) | 2014-10-16 | 2016-05-24 | 대한민국 | 약독화 백시니아 바이러스주 kvac103 |
| EP4122492A1 (en) | 2015-02-25 | 2023-01-25 | Memorial Sloan Kettering Cancer Center | Use of inactivated nonreplicating modified vaccinia virus ankara (mva)as monoimmunotherapy or in combination with immune checkpoint blocking agents for solid tumors |
| KR20180006916A (ko) | 2015-04-17 | 2018-01-19 | 메모리얼 슬로안-케터링 캔서 센터 | 고형 종양에 대한 면역치료제로서 mva 또는 mva델타e3l의 용도 |
| KR20160140075A (ko) * | 2015-05-29 | 2016-12-07 | 코오롱생명과학 주식회사 | 폭스바이러스 유래 프로모터 및 이를 포함하는 벡터 |
| CN107709554A (zh) * | 2015-06-15 | 2018-02-16 | 巴法里安诺迪克有限公司 | 重组经修饰痘苗病毒安卡拉(mva)口蹄疫病毒(fmdv)疫苗 |
| FR3042121A1 (fr) | 2015-10-08 | 2017-04-14 | Jean-Marc Limacher | Composition anti-tumorale |
| CN106591361A (zh) * | 2015-10-20 | 2017-04-26 | 钱文斌 | 一种重组痘溶瘤病毒及其构建方法和应用 |
| EP3402802B1 (en) * | 2016-01-08 | 2023-04-12 | Geovax, Inc. | Compositions and methods for generating an immune response to a tumor associated antigen |
| US10881725B2 (en) | 2016-01-29 | 2021-01-05 | Bavarian Nordic A/S | Recombinant modified vaccinia virus Ankara (MVA) equine encephalitis virus vaccine |
| BR112018015696A2 (pt) * | 2016-02-03 | 2018-12-26 | Geovax Inc | composições e métodos para gerar uma resposta imune para um flavivírus |
| CN109152827B (zh) | 2016-02-25 | 2023-07-21 | 纪念斯隆凯特琳癌症中心 | 重组mva或表达人flt3l的mvaδe3l及其作为抗固体肿瘤的免疫治疗剂的用途 |
| JP7025339B2 (ja) | 2016-02-25 | 2022-02-24 | メモリアル スローン ケタリング キャンサー センター | 癌免疫療法のための、チミジンキナーゼの欠失を伴い、ヒトflt3lまたはgm-csfの発現を伴うかまたは伴わない、複製可能な弱毒化ワクシニアウイルス |
| EP3452087A1 (en) | 2016-05-02 | 2019-03-13 | Janssen Vaccines & Prevention B.V. | Therapeutic hpv vaccine combinations |
| WO2018032057A1 (en) * | 2016-08-19 | 2018-02-22 | Sementis Limited | Viral vaccines |
| WO2018064516A1 (en) * | 2016-09-30 | 2018-04-05 | Monsanto Technology Llc | Method for selecting target sites for site-specific genome modification in plants |
| EP3621646A4 (en) | 2017-05-12 | 2021-06-02 | Memorial Sloan Kettering Cancer Center | VACCINIA VIRUS MUTANTS FOR CANCER IMMUNOTHERAPY |
| CN110958887B (zh) * | 2017-06-15 | 2023-10-31 | 扬森疫苗与预防公司 | 编码hiv抗原的痘病毒载体及其使用方法 |
| US11311612B2 (en) | 2017-09-19 | 2022-04-26 | Geovax, Inc. | Compositions and methods for generating an immune response to treat or prevent malaria |
| EP3790578A4 (en) | 2018-05-11 | 2022-04-06 | City of Hope | Genetically modified recombinant vaccinia ankara (rmva) vaccines of improved stability and methods of preparation thereof |
| CN112512569A (zh) | 2018-05-11 | 2021-03-16 | 希望之城 | 表达多个巨细胞病毒(cmv)抗原的mva载体及其用途 |
| BR112021004692A2 (pt) | 2018-09-15 | 2021-06-08 | Memorial Sloan Kettering Cancer Center | poxvírus recombinantes para imunoterapia de câncer |
| CN111979204B (zh) * | 2019-05-24 | 2023-10-13 | 杭州功楚生物科技有限公司 | 携带海绵凝集素基因的溶瘤痘苗病毒、构建方法及用途 |
| CA3161633A1 (en) | 2019-11-14 | 2021-05-20 | Aelix Therapeutics, S.L. | Dosage regimens for vaccines |
| EP3842065A1 (en) * | 2019-12-23 | 2021-06-30 | Transgene | Process for designing a recombinant poxvirus for a therapeutic vaccine |
| JP2023513611A (ja) | 2020-02-14 | 2023-03-31 | ゲオバックス インコーポレイテッド | Sars-cov2に対する免疫応答を誘導するためのワクチン及びその利用 |
| TW202203966A (zh) * | 2020-03-31 | 2022-02-01 | 澳大利亞商賽門蒂斯公司 | 用於防範covid-19之以減毒的痘病毒載體為底質之疫苗 |
| MX2023009008A (es) | 2021-02-02 | 2023-10-05 | Geovax Inc | Constructos virales para usarse en potenciar el cebado de linfocitos t durante la vacunación. |
| CA3260631A1 (en) | 2022-07-08 | 2024-01-11 | Viromissile, Inc. | Oncolytic and recombinant vaccine viruses and their methods of use |
| FR3160186A1 (fr) | 2024-03-13 | 2025-09-19 | Odimma Therapeutics | Vecteur non-viral pour transcription augmentee |
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| US5338683A (en) | 1981-12-24 | 1994-08-16 | Health Research Incorporated | Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins |
| JPH0795956B2 (ja) * | 1986-09-22 | 1995-10-18 | 京都大学長 | ポックスウイルス由来発現制御領域 |
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| PL212047B1 (pl) | 2000-11-23 | 2012-08-31 | Bavarian Nordic As | Zmodyfikowany wirus krowianki szczepu Ankara MVA-BN i jego pochodna, genom i zawierające je kompozycja farmaceutyczna, zwłaszcza szczepionka oraz ich zastosowania |
| US7501127B2 (en) | 2002-05-16 | 2009-03-10 | Bavarian Nordic A/S | Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara |
| CN102703393A (zh) | 2002-05-16 | 2012-10-03 | 巴法里安诺迪克有限公司 | 表达插入痘病毒基因组中的同源基因的重组痘病毒 |
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-
2003
- 2003-05-14 CN CN2012101928085A patent/CN102703393A/zh active Pending
- 2003-05-14 EA EA200401506A patent/EA012160B1/ru not_active IP Right Cessation
- 2003-05-14 BR BRPI0311178A patent/BRPI0311178B8/pt not_active IP Right Cessation
- 2003-05-14 EA EA200401507A patent/EA007811B1/ru not_active IP Right Cessation
- 2003-05-14 JP JP2004506500A patent/JP4895505B2/ja not_active Expired - Lifetime
- 2003-05-14 AU AU2003236646A patent/AU2003236646B2/en not_active Expired
- 2003-05-14 PL PL372088A patent/PL218318B1/pl unknown
- 2003-05-14 KR KR1020117031095A patent/KR20120002627A/ko not_active Withdrawn
- 2003-05-14 CN CNB038111225A patent/CN100494388C/zh not_active Expired - Lifetime
- 2003-05-14 KR KR1020107021891A patent/KR101138067B1/ko not_active Expired - Lifetime
- 2003-05-14 MX MXPA04011194A patent/MXPA04011194A/es active IP Right Grant
- 2003-05-14 SI SI200330215T patent/SI1407033T1/sl unknown
- 2003-05-14 AT AT03752741T patent/ATE315660T1/de active
- 2003-05-14 ES ES03752741T patent/ES2256776T3/es not_active Expired - Lifetime
- 2003-05-14 UA UA20041109409A patent/UA82479C2/uk unknown
- 2003-05-14 EP EP10008120.7A patent/EP2253709B1/en not_active Expired - Lifetime
- 2003-05-14 BR BR0310051A patent/BR0310051A/pt not_active IP Right Cessation
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