JP2010162030A5 - - Google Patents
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- Publication number
- JP2010162030A5 JP2010162030A5 JP2010036225A JP2010036225A JP2010162030A5 JP 2010162030 A5 JP2010162030 A5 JP 2010162030A5 JP 2010036225 A JP2010036225 A JP 2010036225A JP 2010036225 A JP2010036225 A JP 2010036225A JP 2010162030 A5 JP2010162030 A5 JP 2010162030A5
- Authority
- JP
- Japan
- Prior art keywords
- library
- phage
- kunitz domain
- protein
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000623 proteins and genes Proteins 0.000 claims 28
- 239000002245 particle Substances 0.000 claims 17
- 102000004169 proteins and genes Human genes 0.000 claims 14
- 101710132601 Capsid protein Proteins 0.000 claims 11
- 101710094648 Coat protein Proteins 0.000 claims 11
- 102100021181 Golgi phosphoprotein 3 Human genes 0.000 claims 11
- 101710125418 Major capsid protein Proteins 0.000 claims 11
- 101710141454 Nucleoprotein Proteins 0.000 claims 11
- 101710083689 Probable capsid protein Proteins 0.000 claims 11
- 102000039446 nucleic acids Human genes 0.000 claims 6
- 108020004707 nucleic acids Proteins 0.000 claims 6
- 150000007523 nucleic acids Chemical class 0.000 claims 6
- 125000003275 alpha amino acid group Chemical group 0.000 claims 5
- 230000003993 interaction Effects 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 3
- 229910052739 hydrogen Inorganic materials 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 230000002458 infectious effect Effects 0.000 claims 3
- 241000724791 Filamentous phage Species 0.000 claims 1
- 108091005804 Peptidases Proteins 0.000 claims 1
- 239000004365 Protease Substances 0.000 claims 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43849103P | 2003-01-07 | 2003-01-07 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006500832A Division JP2007524348A (ja) | 2003-01-07 | 2004-01-07 | クニッツドメインライブラリー |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010162030A JP2010162030A (ja) | 2010-07-29 |
| JP2010162030A5 true JP2010162030A5 (enExample) | 2011-06-30 |
Family
ID=32713336
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006500832A Pending JP2007524348A (ja) | 2003-01-07 | 2004-01-07 | クニッツドメインライブラリー |
| JP2010036225A Pending JP2010162030A (ja) | 2003-01-07 | 2010-02-22 | クニッツドメインライブラリー |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006500832A Pending JP2007524348A (ja) | 2003-01-07 | 2004-01-07 | クニッツドメインライブラリー |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20040209243A1 (enExample) |
| EP (2) | EP2290107A1 (enExample) |
| JP (2) | JP2007524348A (enExample) |
| AT (1) | ATE500345T1 (enExample) |
| AU (1) | AU2004204095B2 (enExample) |
| CA (1) | CA2512590A1 (enExample) |
| DE (1) | DE602004031589D1 (enExample) |
| DK (1) | DK1587907T3 (enExample) |
| ES (1) | ES2362424T3 (enExample) |
| PT (1) | PT1587907E (enExample) |
| WO (1) | WO2004063337A2 (enExample) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
| EP0737207B1 (en) * | 1994-01-11 | 2004-09-22 | Dyax Corporation | Inhibitors of human plasmin derived from the kunitz domains |
| PT2298278E (pt) | 2002-06-07 | 2016-02-25 | Dyax Corp | Prevenção e redução da perda de sangue e resposta inflamatória |
| US7153829B2 (en) | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
| US7235530B2 (en) | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
| WO2006057997A2 (en) * | 2004-11-22 | 2006-06-01 | Dyax Corp. | Plasmin-inhibitory therapies |
| MX2008000230A (es) * | 2005-07-13 | 2008-04-07 | Amgen Mountain View Inc | Proteinas de enlace il-6. |
| WO2009026334A2 (en) * | 2007-08-21 | 2009-02-26 | Genzyme Corporation | Treatment with kallikrein inhibitors |
| EP2379096B1 (en) | 2008-12-19 | 2019-10-30 | Baxalta GmbH | Tfpi inhibitors and methods of use |
| JP2013516389A (ja) | 2009-01-06 | 2013-05-13 | ダイアックス コーポレーション | カリクレイン阻害剤による粘膜炎治療 |
| ES2905545T3 (es) | 2010-01-06 | 2022-04-11 | Takeda Pharmaceuticals Co | Proteínas de unión a calicreína plasmática |
| ES2983470T3 (es) | 2010-03-19 | 2024-10-23 | Takeda Pharmaceuticals Co | Inhibidores del TFPI y métodos de uso |
| KR102011156B1 (ko) | 2011-01-06 | 2019-08-16 | 다이액스 코포레이션 | 혈장 칼리크레인 결합 단백질 |
| BR112014022435B1 (pt) | 2012-03-21 | 2023-02-14 | Takeda Pharmaceutical Company Limited | Inibidores de tfpi e métodos de uso |
| CA2881431C (en) | 2012-08-08 | 2021-10-19 | Daiichi Sankyo Company, Limited | Peptide library and use thereof |
| IL247942B (en) | 2014-03-27 | 2022-09-01 | Dyax Corp | Compositions and methods for drops in macular edema as a result of diabetes |
| PT3177644T (pt) | 2014-08-05 | 2021-01-13 | MabQuest SA | Reagentes imunológicos que se ligam a pd-1 |
| US9982052B2 (en) | 2014-08-05 | 2018-05-29 | MabQuest, SA | Immunological reagents |
| JP6743022B2 (ja) | 2014-12-24 | 2020-08-19 | ネクシミューン インコーポレイテッド | 免疫療法のためのナノ粒子組成物及び方法 |
| EP3371311B1 (en) | 2015-11-06 | 2021-07-21 | Orionis Biosciences BV | Bi-functional chimeric proteins and uses thereof |
| EP3377080B1 (en) | 2015-11-19 | 2024-02-14 | Asclepix Therapeutics, LLC | Peptides with anti-angiogenic, anti-lymphangiogenic, and anti-edemic properties and nanoparticle formulations |
| US11286307B2 (en) | 2015-12-11 | 2022-03-29 | Takeda Pharmaceutical Company Limited | Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack |
| PL3964529T3 (pl) | 2016-01-22 | 2025-10-27 | MabQuest SA | Nieblokujące przeciwciała specyficzne względem pd1 |
| US11214617B2 (en) | 2016-01-22 | 2022-01-04 | MabQuest SA | Immunological reagents |
| CN109071632B (zh) | 2016-02-05 | 2022-12-30 | 奥里尼斯生物科学私人有限公司 | 靶向性治疗剂及其用途 |
| US11248057B2 (en) | 2016-03-07 | 2022-02-15 | Vib Vzw | CD20 binding single domain antibodies |
| EP3455245A2 (en) | 2016-05-13 | 2019-03-20 | Orionis Biosciences NV | Therapeutic targeting of non-cellular structures |
| WO2017194783A1 (en) | 2016-05-13 | 2017-11-16 | Orionis Biosciences Nv | Targeted mutant interferon-beta and uses thereof |
| WO2018067646A1 (en) | 2016-10-04 | 2018-04-12 | Asclepix Therapeutics, Llc | Compounds and methods for activating tie2 signaling |
| CN110114368B (zh) | 2016-10-24 | 2024-08-02 | 奥睿尼斯生物科学私人有限公司 | 靶向突变干扰素-γ及其用途 |
| KR102642385B1 (ko) | 2017-02-06 | 2024-03-04 | 오리오니스 바이오사이언시스 엔브이 | 표적화된 키메라 단백질 및 이의 용도 |
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| CA3050601A1 (en) | 2017-02-07 | 2018-08-16 | Vib Vzm | Immune-cell targeted bispecific chimeric proteins and uses thereof |
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| WO2019075056A1 (en) | 2017-10-10 | 2019-04-18 | The Johns Hopkins University | BIODEGRADABLE BIOMIMETIC PARTICLES |
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| JP7491573B2 (ja) | 2018-02-07 | 2024-05-28 | エル．イー．エー．エフ． ホールディングス グループ エルエルシー | アルファポリグルタミン酸化メトトレキセートおよびその使用 |
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| CA3090391A1 (en) | 2018-02-07 | 2019-08-15 | L.E.A.F. Holdings Group Llc | Gamma polyglutamated raltitrexed and uses thereof |
| CA3090384A1 (en) | 2018-02-07 | 2019-08-15 | L.E.A.F. Holdings Group Llc | Alpha polyglutamated aminopterin and uses thereof |
| WO2019157133A1 (en) | 2018-02-07 | 2019-08-15 | L.E.A.F. Holdings Group Llc | Alpha polyglutamated raltitrexed and uses thereof |
| US12048767B2 (en) | 2018-02-14 | 2024-07-30 | L.E.A.F. Holdings Group Llc | Gamma polyglutamated pralatrexate and uses thereof |
| US12290518B2 (en) | 2018-02-14 | 2025-05-06 | L.E.A.F. Holdings Group Llc | Gamma polyglutamated methotrexate and uses thereof |
| CA3090943A1 (en) | 2018-02-14 | 2019-08-22 | L.E.A.F. Holdings Group Llc | Gamma polyglutamated aminopterin and uses thereof |
| CA3090875A1 (en) | 2018-02-14 | 2019-08-22 | L.E.A.F. Holdings Group Llc | Gamma polyglutamated lometrexol and uses thereof |
| EP3890773A4 (en) | 2018-11-08 | 2022-11-09 | Orionis Biosciences, Inc. | MODULATION OF DENDRITIC CELL LINES |
| CN119708241A (zh) | 2019-02-15 | 2025-03-28 | 因特格尔莫来库乐有限公司 | 密封蛋白6抗体及其用途 |
| US11254736B2 (en) | 2019-02-15 | 2022-02-22 | Integral Molecular, Inc. | Antibodies comprising a common light chain and uses thereof |
| WO2020198665A1 (en) | 2019-03-28 | 2020-10-01 | Orionis Biosciences, Inc. | Fibroblast activation protein binding agents and use thereof |
| CA3149914A1 (en) | 2019-08-06 | 2021-02-11 | L.E.A.F. Holdings Group Llc | Processes of preparing polyglutamated antifolates and uses of their compositions |
| AU2021209045A1 (en) | 2020-01-13 | 2022-07-28 | Takeda Pharmaceutical Company Limited | Plasma kallikrein inhibitors and uses thereof for treating pediatric hereditary angioedema attack |
| GB202004514D0 (en) | 2020-03-27 | 2020-05-13 | Inst De Medicina Molecular Joaeo Lobo Antunes | Treatment of Immunosuppressive Cancer |
| CA3195512A1 (en) | 2020-10-14 | 2022-04-21 | Vahe Bedian | Compositions and methods for treatment of thyroid eye disease |
| GB202019817D0 (en) * | 2020-12-15 | 2021-01-27 | Univ Oxford Innovation Ltd | Ligand-binding polypeptides and uses thereof |
| BR112023019689A2 (pt) | 2021-03-26 | 2023-10-31 | Arcellx Inc | Terapias multifuncionais de célula imunológica |
| JP2024531151A (ja) | 2021-08-10 | 2024-08-29 | ビリジアン セラピューティクス， インコーポレイテッド | 甲状腺眼疾患の処置のための組成物、用量および方法 |
| US20250304677A1 (en) | 2022-07-04 | 2025-10-02 | Vib Vzw | Blood-Cerebrospinal Fluid Barrier Crossing Antibodies |
| AU2023356326A1 (en) | 2022-10-06 | 2025-03-27 | Bicara Therapeutics Inc. | Multispecific proteins and related methods |
| CN120282987A (zh) | 2022-11-30 | 2025-07-08 | 因特格尔莫来库乐有限公司 | 包括双特异性型式的针对紧密连接蛋白6的抗体 |
| JP2026519919A (ja) | 2023-04-03 | 2026-06-19 | ブイアイビー ブイゼットダブリュ | 血液脳関門通過抗体 |
| CN122003247A (zh) | 2023-07-07 | 2026-05-08 | 维里迪安治疗公司 | 治疗活动性和慢性甲状腺眼病的方法 |
| KR20260044219A (ko) | 2023-07-21 | 2026-04-01 | 매로우 테라퓨틱스, 인크. | 조혈 세포 표적화 접합체 및 관련 방법 |
| AU2024373680A1 (en) | 2023-11-03 | 2026-06-18 | Neuvasq Biotechnologies Sa | Wnt7 signaling agonists |
| AU2024408268A1 (en) | 2023-12-17 | 2026-07-09 | Viridian Therapeutics, Inc. | Compositions, doses, and methods for treatment of thyroid eye disease |
| WO2025151492A1 (en) | 2024-01-09 | 2025-07-17 | Viridian Therapeutics, Inc. | Compositions and methods for treatment of thyroid eye disease |
| WO2025151496A1 (en) | 2024-01-09 | 2025-07-17 | Viridian Therapeutics, Inc. | Compositions and methods for treatment of thyroid eye disease |
| WO2025151502A1 (en) | 2024-01-09 | 2025-07-17 | Viridian Therapeutics, Inc. | Modified antibodies |
| US20250375499A1 (en) | 2024-01-26 | 2025-12-11 | Flagship Pioneering Innovations Vii, Llc | Immunoreceptor inhibitory proteins and related methods |
| TW202613158A (zh) | 2024-05-16 | 2026-04-01 | 美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 | 免疫受體抑制蛋白及相關方法 |
| WO2025245111A1 (en) | 2024-05-22 | 2025-11-27 | Flagship Pioneering Innovations Vii, Llc | Immunoreceptor targeting proteins and related methods |
| US20260015407A1 (en) | 2024-07-15 | 2026-01-15 | Flagship Pioneering Innovations Vii, Llc | Immunomodulatory fusion proteins and related methods |
| WO2026122747A2 (en) | 2024-12-05 | 2026-06-11 | Flagship Pioneering Innovations Vii, Llc | Novel immunomodulatory proteins and related methods |
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-
2004
- 2004-01-07 PT PT04700617T patent/PT1587907E/pt unknown
- 2004-01-07 AU AU2004204095A patent/AU2004204095B2/en not_active Ceased
- 2004-01-07 JP JP2006500832A patent/JP2007524348A/ja active Pending
- 2004-01-07 EP EP10012620A patent/EP2290107A1/en not_active Withdrawn
- 2004-01-07 DE DE602004031589T patent/DE602004031589D1/de not_active Expired - Lifetime
- 2004-01-07 DK DK04700617.6T patent/DK1587907T3/da active
- 2004-01-07 CA CA002512590A patent/CA2512590A1/en not_active Abandoned
- 2004-01-07 WO PCT/US2004/000333 patent/WO2004063337A2/en not_active Ceased
- 2004-01-07 US US10/753,544 patent/US20040209243A1/en not_active Abandoned
- 2004-01-07 AT AT04700617T patent/ATE500345T1/de active
- 2004-01-07 ES ES04700617T patent/ES2362424T3/es not_active Expired - Lifetime
- 2004-01-07 EP EP04700617A patent/EP1587907B1/en not_active Expired - Lifetime
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2007
- 2007-07-09 US US11/774,964 patent/US20080020394A1/en not_active Abandoned
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2010
- 2010-02-22 JP JP2010036225A patent/JP2010162030A/ja active Pending