DE602004031589D1 - Kunitz-domäne-bibliothek - Google Patents

Kunitz-domäne-bibliothek

Info

Publication number
DE602004031589D1
DE602004031589D1 DE602004031589T DE602004031589T DE602004031589D1 DE 602004031589 D1 DE602004031589 D1 DE 602004031589D1 DE 602004031589 T DE602004031589 T DE 602004031589T DE 602004031589 T DE602004031589 T DE 602004031589T DE 602004031589 D1 DE602004031589 D1 DE 602004031589D1
Authority
DE
Germany
Prior art keywords
kunitz domain
domain library
libraries
kunitz
phage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004031589T
Other languages
English (en)
Inventor
Robert Charles Ladner
Andrew Nixon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dyax Corp
Original Assignee
Dyax Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyax Corp filed Critical Dyax Corp
Publication of DE602004031589D1 publication Critical patent/DE602004031589D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Gyroscopes (AREA)
  • Optical Communication System (AREA)
DE602004031589T 2003-01-07 2004-01-07 Kunitz-domäne-bibliothek Expired - Lifetime DE602004031589D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43849103P 2003-01-07 2003-01-07
PCT/US2004/000333 WO2004063337A2 (en) 2003-01-07 2004-01-07 Kunitz domain library

Publications (1)

Publication Number Publication Date
DE602004031589D1 true DE602004031589D1 (de) 2011-04-14

Family

ID=32713336

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004031589T Expired - Lifetime DE602004031589D1 (de) 2003-01-07 2004-01-07 Kunitz-domäne-bibliothek

Country Status (11)

Country Link
US (2) US20040209243A1 (de)
EP (2) EP1587907B1 (de)
JP (2) JP2007524348A (de)
AT (1) ATE500345T1 (de)
AU (1) AU2004204095B2 (de)
CA (1) CA2512590A1 (de)
DE (1) DE602004031589D1 (de)
DK (1) DK1587907T3 (de)
ES (1) ES2362424T3 (de)
PT (1) PT1587907E (de)
WO (1) WO2004063337A2 (de)

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RS62853B1 (sr) 2010-01-06 2022-02-28 Takeda Pharmaceuticals Co Proteini koji vezuju kalikrein plazme
CN103025345B (zh) 2010-03-19 2016-01-20 巴克斯特国际公司 Tfpi抑制剂及使用方法
AU2012204202A1 (en) 2011-01-06 2013-07-11 Dyax Corp. Plasma kallikrein binding proteins
AU2013235741C1 (en) 2012-03-21 2017-12-21 Takeda Pharmaceutical Company Limited TFPI inhibitors and methods of use
EP3748001A1 (de) 2012-08-08 2020-12-09 Daiichi Sankyo Company, Limited Peptidbank und verwendung davon
CN106459210A (zh) 2014-03-27 2017-02-22 戴埃克斯有限公司 用于治疗糖尿病黄斑性水肿的组合物和方法
US9982052B2 (en) 2014-08-05 2018-05-29 MabQuest, SA Immunological reagents
ES2847311T3 (es) 2014-08-05 2021-08-02 MabQuest SA Reactivos inmunológicos que se unen a PD-1
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AU2017208819B2 (en) 2016-01-22 2023-10-19 MabQuest SA PD1 specific antibodies
US11214617B2 (en) 2016-01-22 2022-01-04 MabQuest SA Immunological reagents
EP4059957A1 (de) 2016-02-05 2022-09-21 Orionis Biosciences BV Bispezifische signalisierungsmittel und verwendungen davon
WO2017153402A1 (en) 2016-03-07 2017-09-14 Vib Vzw Cd20 binding single domain antibodies
EP3455245A2 (de) 2016-05-13 2019-03-20 Orionis Biosciences NV Therapeutisches targeting von nichtzellulären strukturen
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CN110177563A (zh) 2016-10-04 2019-08-27 阿斯克雷佩西治疗公司 用于激活tie2信号传导的化合物和方法
US11084859B2 (en) 2016-10-24 2021-08-10 Orionis Biosciences BV Targeted mutant interferon-gamma and uses thereof
CA3052523A1 (en) 2017-02-06 2018-08-09 Orionis Biosciences Nv Targeted chimeric proteins and uses thereof
WO2018144999A1 (en) 2017-02-06 2018-08-09 Orionis Biosciences, Inc. Targeted engineered interferon and uses thereof
EP3580230A1 (de) 2017-02-07 2019-12-18 VIB vzw Auf immunzellen gerichtete bispezifische chimäre proteine und verwendungen davon
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US11896643B2 (en) 2018-02-05 2024-02-13 Orionis Biosciences, Inc. Fibroblast binding agents and use thereof
JP2022520632A (ja) 2019-02-15 2022-03-31 インテグラル・モレキュラー・インコーポレイテッド 共通軽鎖を含む抗体及びその使用
CN113767113A (zh) 2019-02-15 2021-12-07 因特格尔莫来库乐有限公司 密封蛋白6抗体及其用途
CA3149914A1 (en) 2019-08-06 2021-02-11 L.E.A.F. Holdings Group Llc Processes of preparing polyglutamated antifolates and uses of their compositions
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Also Published As

Publication number Publication date
US20040209243A1 (en) 2004-10-21
US20080020394A1 (en) 2008-01-24
JP2010162030A (ja) 2010-07-29
EP1587907A4 (de) 2007-11-14
EP2290107A1 (de) 2011-03-02
WO2004063337A2 (en) 2004-07-29
ATE500345T1 (de) 2011-03-15
EP1587907A2 (de) 2005-10-26
CA2512590A1 (en) 2004-07-29
DK1587907T3 (da) 2011-04-04
AU2004204095B2 (en) 2009-07-30
EP1587907B1 (de) 2011-03-02
JP2007524348A (ja) 2007-08-30
AU2004204095A1 (en) 2004-07-29
ES2362424T3 (es) 2011-07-05
PT1587907E (pt) 2011-04-08
WO2004063337A3 (en) 2007-01-25

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