DE602004031589D1 - Kunitz-domäne-bibliothek - Google Patents
Kunitz-domäne-bibliothekInfo
- Publication number
- DE602004031589D1 DE602004031589D1 DE602004031589T DE602004031589T DE602004031589D1 DE 602004031589 D1 DE602004031589 D1 DE 602004031589D1 DE 602004031589 T DE602004031589 T DE 602004031589T DE 602004031589 T DE602004031589 T DE 602004031589T DE 602004031589 D1 DE602004031589 D1 DE 602004031589D1
- Authority
- DE
- Germany
- Prior art keywords
- kunitz domain
- domain library
- libraries
- kunitz
- phage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003993 interaction Effects 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Gyroscopes (AREA)
- Optical Communication System (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43849103P | 2003-01-07 | 2003-01-07 | |
| PCT/US2004/000333 WO2004063337A2 (en) | 2003-01-07 | 2004-01-07 | Kunitz domain library |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602004031589D1 true DE602004031589D1 (de) | 2011-04-14 |
Family
ID=32713336
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004031589T Expired - Lifetime DE602004031589D1 (de) | 2003-01-07 | 2004-01-07 | Kunitz-domäne-bibliothek |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20040209243A1 (enExample) |
| EP (2) | EP1587907B1 (enExample) |
| JP (2) | JP2007524348A (enExample) |
| AT (1) | ATE500345T1 (enExample) |
| AU (1) | AU2004204095B2 (enExample) |
| CA (1) | CA2512590A1 (enExample) |
| DE (1) | DE602004031589D1 (enExample) |
| DK (1) | DK1587907T3 (enExample) |
| ES (1) | ES2362424T3 (enExample) |
| PT (1) | PT1587907E (enExample) |
| WO (1) | WO2004063337A2 (enExample) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69533544T2 (de) * | 1994-01-11 | 2006-02-23 | Dyax Corp., Cambridge | Inhibitoren des humanplasmins, die sich von den kunitz domänen ableiten |
| US6057287A (en) | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
| PT1941867E (pt) | 2002-06-07 | 2012-02-16 | Dyax Corp | Polipeptídeo contendo um domínio kunitz modificado |
| US7153829B2 (en) | 2002-06-07 | 2006-12-26 | Dyax Corp. | Kallikrein-inhibitor therapies |
| US7235530B2 (en) | 2004-09-27 | 2007-06-26 | Dyax Corporation | Kallikrein inhibitors and anti-thrombolytic agents and uses thereof |
| US20060111296A1 (en) * | 2004-11-22 | 2006-05-25 | Dyax Corp. | Plasmin-inhibitory therapies |
| WO2007009069A2 (en) * | 2005-07-13 | 2007-01-18 | Amgen Mountain View Inc. | Heat lysis production of proteins |
| US20090075887A1 (en) * | 2007-08-21 | 2009-03-19 | Genzyme Corporation | Treatment with Kallikrein Inhibitors |
| SI2379096T1 (sl) | 2008-12-19 | 2020-03-31 | Baxalta GmbH | Zaviralci TFPI in postopki uporabe |
| JP2013516389A (ja) | 2009-01-06 | 2013-05-13 | ダイアックス コーポレーション | カリクレイン阻害剤による粘膜炎治療 |
| HRP20181419T1 (hr) | 2010-01-06 | 2018-11-16 | Dyax Corp. | Plazma kalikrein vezni proteini |
| CA2793465C (en) | 2010-03-19 | 2022-06-14 | Baxter International Inc. | Tfpi inhibitors and methods of use |
| IL269565B2 (en) | 2011-01-06 | 2024-06-01 | Dyax Corp | Plasma kallikrein binding proteins |
| NZ724133A (en) | 2012-03-21 | 2020-07-31 | Baxalta Inc | Tfpi inhibitors and methods of use |
| WO2014024914A1 (ja) | 2012-08-08 | 2014-02-13 | 第一三共株式会社 | ペプチド・ライブラリー及びその利用 |
| KR102555955B1 (ko) | 2014-03-27 | 2023-07-18 | 다케다 파머수티컬 컴패니 리미티드 | 당뇨병성 황반 부종의 치료를 위한 조성물 및 방법 |
| KR102357893B1 (ko) | 2014-08-05 | 2022-02-04 | 맵퀘스트 에스아 | Pd-1 에 결합하는 면역학적 시약 |
| US9982052B2 (en) | 2014-08-05 | 2018-05-29 | MabQuest, SA | Immunological reagents |
| EP3970748B1 (en) | 2014-12-24 | 2024-07-24 | NexImmune, Inc. | Nanoparticle compositions and methods for immunotherapy |
| EP3371311B1 (en) | 2015-11-06 | 2021-07-21 | Orionis Biosciences BV | Bi-functional chimeric proteins and uses thereof |
| KR20180081608A (ko) | 2015-11-19 | 2018-07-16 | 아스클리픽스 테라퓨틱스, 엘엘씨. | 항-혈관형성, 항-림프관신생, 및 항-부종성 특성을 가진 펩티드 및 나노입자 제제 |
| WO2017100679A1 (en) | 2015-12-11 | 2017-06-15 | Dyax Corp. | Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack |
| US11214617B2 (en) | 2016-01-22 | 2022-01-04 | MabQuest SA | Immunological reagents |
| DK3964529T3 (da) | 2016-01-22 | 2025-06-30 | MabQuest SA | Ikke-blokerende pd1-specifikke antistoffer |
| EP3411065B1 (en) | 2016-02-05 | 2021-03-31 | Orionis Biosciences BV | Clec9a binding agents |
| US11248057B2 (en) | 2016-03-07 | 2022-02-15 | Vib Vzw | CD20 binding single domain antibodies |
| CN109689087B (zh) | 2016-05-13 | 2023-04-04 | 奥里尼斯生物科学私人有限公司 | 靶向性突变干扰素-β及其用途 |
| EP3455245A2 (en) | 2016-05-13 | 2019-03-20 | Orionis Biosciences NV | Therapeutic targeting of non-cellular structures |
| KR20190066040A (ko) | 2016-10-04 | 2019-06-12 | 아스클리픽스 테라퓨틱스, 인크. | Tie2 신호전달을 활성화시키기 위한 화합물 및 방법 |
| ES2917000T3 (es) | 2016-10-24 | 2022-07-06 | Orionis Biosciences BV | Interferón-gamma mutante diana y usos del mismo |
| EP3577133A1 (en) | 2017-02-06 | 2019-12-11 | Orionis Biosciences NV | Targeted chimeric proteins and uses thereof |
| US10906985B2 (en) | 2017-02-06 | 2021-02-02 | Orionis Biosciences, Inc. | Targeted engineered interferon and uses thereof |
| EP3580230A1 (en) | 2017-02-07 | 2019-12-18 | VIB vzw | Immune-cell targeted bispecific chimeric proteins and uses thereof |
| WO2019028427A1 (en) | 2017-08-03 | 2019-02-07 | Asclepix Therapeutics, Llc. | METHODS OF IDENTIFYING AND PREPARING PHARMACEUTICAL AGENTS TO ACTIVATE TIE2 RECEPTOR |
| WO2019075056A1 (en) | 2017-10-10 | 2019-04-18 | The Johns Hopkins University | BIODEGRADABLE BIOMIMETIC PARTICLES |
| EP3706801A4 (en) | 2017-11-08 | 2022-04-06 | L.E.A.F Holdings Group LLC | PLATINUM COMPLEXES AND USES THEREOF |
| IL314701A (en) | 2017-11-14 | 2024-10-01 | Arcellx Inc | Multifunctional immune cell therapies |
| WO2019148089A1 (en) | 2018-01-26 | 2019-08-01 | Orionis Biosciences Inc. | Xcr1 binding agents and uses thereof |
| WO2019152979A1 (en) | 2018-02-05 | 2019-08-08 | Orionis Biosciences, Inc. | Fibroblast binding agents and use thereof |
| US12410225B2 (en) | 2018-11-08 | 2025-09-09 | Orionis Biosciences, Inc | Modulation of dendritic cell lineages |
| CN113661175A (zh) | 2019-02-15 | 2021-11-16 | 整体分子公司 | 包含共同轻链的抗体及其用途 |
| CA3129834A1 (en) | 2019-02-15 | 2020-08-20 | Integral Molecular, Inc. | Claudin 6 antibodies and uses thereof |
| CA3149914A1 (en) | 2019-08-06 | 2021-02-11 | L.E.A.F. Holdings Group Llc | Processes of preparing polyglutamated antifolates and uses of their compositions |
| GB202004514D0 (en) | 2020-03-27 | 2020-05-13 | Inst De Medicina Molecular Joaeo Lobo Antunes | Treatment of Immunosuppressive Cancer |
| PE20231202A1 (es) | 2020-10-14 | 2023-08-17 | Viridian Therapeutics Inc | Composiciones y metodos para el tratamiento de la enfermedad ocular tiroidea |
| GB202019817D0 (en) * | 2020-12-15 | 2021-01-27 | Univ Oxford Innovation Ltd | Ligand-binding polypeptides and uses thereof |
| EP4313083A4 (en) | 2021-03-26 | 2025-06-18 | Arcellx, Inc. | MULTIFUNCTIONAL IMMUNE CELL THERAPIES |
| TW202320850A (zh) | 2021-08-10 | 2023-06-01 | 美商維里迪恩醫療股份有限公司 | 用於治療甲狀腺眼病之組合物、劑量及方法 |
| EP4551600A1 (en) | 2022-07-04 | 2025-05-14 | Vib Vzw | Blood-cerebrospinal fluid barrier crossing antibodies |
| CN120322459A (zh) | 2022-10-06 | 2025-07-15 | 比卡拉治疗股份有限公司 | 多特异性蛋白及相关方法 |
| EP4626933A1 (en) | 2022-11-30 | 2025-10-08 | Integral Molecular, Inc. | Antibodies directed to claudin 6, including bispecific formats thereof |
| AU2024243709A1 (en) | 2023-04-03 | 2025-11-06 | Katholieke Universiteit Leuven | Blood-brain barrier crossing antibodies |
| TW202509078A (zh) | 2023-07-07 | 2025-03-01 | 美商維里迪恩醫療股份有限公司 | 治療慢性甲狀腺眼病之方法 |
| WO2025024334A1 (en) | 2023-07-21 | 2025-01-30 | Marrow Therapeutics, Inc. | Hematopoietic cell targeting conjugates and related methods |
| WO2025093683A1 (en) | 2023-11-03 | 2025-05-08 | Neuvasq Biotechnologies Sa | Wnt7 signaling agonists |
| TW202535948A (zh) | 2023-12-17 | 2025-09-16 | 美商維里迪恩醫療股份有限公司 | 用於治療甲狀腺眼病之組合物、劑量及方法 |
| WO2025151496A1 (en) | 2024-01-09 | 2025-07-17 | Viridian Therapeutics, Inc. | Compositions and methods for treatment of thyroid eye disease |
| WO2025151492A1 (en) | 2024-01-09 | 2025-07-17 | Viridian Therapeutics, Inc. | Compositions and methods for treatment of thyroid eye disease |
| WO2025151502A1 (en) | 2024-01-09 | 2025-07-17 | Viridian Therapeutics, Inc. | Modified antibodies |
| WO2025160334A1 (en) | 2024-01-26 | 2025-07-31 | Flagship Pioneering Innovations Vii, Llc | Immunoreceptor inhibitory proteins and related methods |
| US20250353881A1 (en) | 2024-05-16 | 2025-11-20 | Flagship Pioneering Innovations Vii, Llc | Immunoreceptor inhibitory proteins and related methods |
| WO2025245111A1 (en) | 2024-05-22 | 2025-11-27 | Flagship Pioneering Innovations Vii, Llc | Immunoreceptor targeting proteins and related methods |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9690A (en) * | 1853-04-26 | Eadiator fob stoves | ||
| US53206A (en) * | 1866-03-13 | Improvement in linings for artificial limbs | ||
| US38893A (en) * | 1863-06-16 | Improvement in apparatus for the manufacture of salt | ||
| US4475196A (en) | 1981-03-06 | 1984-10-02 | Zor Clair G | Instrument for locating faults in aircraft passenger reading light and attendant call control system |
| US4447233A (en) | 1981-04-10 | 1984-05-08 | Parker-Hannifin Corporation | Medication infusion pump |
| US4439196A (en) | 1982-03-18 | 1984-03-27 | Merck & Co., Inc. | Osmotic drug delivery system |
| US4447224A (en) | 1982-09-20 | 1984-05-08 | Infusaid Corporation | Variable flow implantable infusion apparatus |
| US4487603A (en) | 1982-11-26 | 1984-12-11 | Cordis Corporation | Implantable microinfusion pump system |
| US4486194A (en) | 1983-06-08 | 1984-12-04 | James Ferrara | Therapeutic device for administering medicaments through the skin |
| US4760025A (en) | 1984-05-29 | 1988-07-26 | Genencor, Inc. | Modified enzymes and methods for making same |
| AU560584B2 (en) * | 1983-07-28 | 1987-04-09 | Bayer Aktiengesellschaft | Homologues of aprotinin |
| US4657893A (en) * | 1984-05-09 | 1987-04-14 | Syntex (U.S.A.) Inc. | 4H-3,1-benzoxazin-4-ones and related compounds and use as enzyme inhibitors |
| US4845242A (en) * | 1987-04-28 | 1989-07-04 | Georgia Tech Research Corporation | Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| US5654176A (en) | 1987-05-28 | 1997-08-05 | Amrad Corporation Limited | Fusion proteins containing glutathione-s-transferase |
| US4790824A (en) | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
| US4941880A (en) | 1987-06-19 | 1990-07-17 | Bioject, Inc. | Pre-filled ampule and non-invasive hypodermic injection device assembly |
| GB2208511A (en) * | 1987-08-07 | 1989-04-05 | Bayer Ag | Variants of bovine pancreatic trypsin inhibitor produced by recombinant dna technology |
| DK225488D0 (da) * | 1988-04-26 | 1988-04-26 | Novo Industri As | Polypeptid |
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| DE768377T1 (de) | 1988-09-02 | 1998-01-02 | Dyax Corp | Herstellung und Auswahl von Rekombinantproteinen mit verschiedenen Bindestellen |
| DK0401508T3 (da) * | 1989-05-13 | 1995-05-15 | Bayer Ag | Proteaseinhibitorer, fremgangsmåde til deres fremstilling samt lægemidler med indhold deraf |
| US5064413A (en) | 1989-11-09 | 1991-11-12 | Bioject, Inc. | Needleless hypodermic injection device |
| US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| US5278285A (en) * | 1990-02-01 | 1994-01-11 | Bayer Aktiengesellschaft | Variant of Kunitz-type inhibitor derived from the α3-chain of human type VI collagen produced by recombinant DNA technology |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| DK0585287T3 (da) | 1990-07-10 | 2000-04-17 | Cambridge Antibody Tech | Fremgangsmåde til fremstilling af specifikke bindingsparelementer |
| US5583107A (en) * | 1990-09-04 | 1996-12-10 | Cor Therapeutics, Inc. | Agents affecting thrombosis and hemostasis |
| US5278144A (en) * | 1990-09-04 | 1994-01-11 | Cor Therapeutics, Inc. | Antithrombosis agents |
| AU641568B2 (en) * | 1990-11-13 | 1993-09-23 | Mochida Pharmaceutical Co., Ltd. | Polypeptide,DNA fragment encoding the same and process for producing the same, and enzyme inhibition process, drug composition and methods of treating using the same |
| JP3267293B2 (ja) * | 1990-12-03 | 2002-03-18 | ジェネンテク,インコーポレイテッド | 改変された結合性を有する変異タンパク質の豊富化法 |
| CA2095633C (en) | 1990-12-03 | 2003-02-04 | Lisa J. Garrard | Enrichment method for variant proteins with altered binding properties |
| ES2287206T3 (es) | 1991-03-01 | 2007-12-16 | Dyax Corporation | Proceso para el desarrollo de mini-proteinas de union. |
| WO1992018619A1 (en) | 1991-04-10 | 1992-10-29 | The Scripps Research Institute | Heterodimeric receptor libraries using phagemids |
| US5166133A (en) * | 1991-04-17 | 1992-11-24 | Cetus Corporation | Method for inhibing adhesion of white blood cells to endothelial cells |
| DE4122599C2 (de) | 1991-07-08 | 1993-11-11 | Deutsches Krebsforsch | Phagemid zum Screenen von Antikörpern |
| US5866344A (en) * | 1991-11-15 | 1999-02-02 | Board Of Regents, The University Of Texas System | Antibody selection methods using cell surface expressed libraries |
| IL104325A (en) * | 1992-01-07 | 2000-10-31 | Novo Nordisk As | Variants of human kunitz-type protease inhibitor domain II of tissue factor pathway inhibitor (TFPI) pharmaceutical compositions containing them a DNA construct encoding them their expression vectors a cell containing said DNA constructs and methods for the production of all the above |
| IL104314A0 (en) * | 1992-01-07 | 1993-05-13 | Novo Nordisk As | Human kunitz-type protease inhibitor and variants thereof,their production and pharmaceutical compositions containing them |
| IL104327A0 (en) * | 1992-01-07 | 1993-05-13 | Novo Nordisk As | Variant of human kunitz-type protease inhibitor |
| US5869644A (en) | 1992-04-15 | 1999-02-09 | The Johns Hopkins University | Synthesis of diverse and useful collections of oligonucleotidies |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| WO1995007986A1 (en) * | 1993-09-14 | 1995-03-23 | Genentech, Inc. | Pharmaceutical compositions containing ecotin and homologs thereof |
| DE69533472T2 (de) * | 1994-01-11 | 2006-01-12 | Dyax Corp., Cambridge | Kallikreinhemmende "kunitz-domäne"-proteine und derivaten davon |
| US6057287A (en) * | 1994-01-11 | 2000-05-02 | Dyax Corp. | Kallikrein-binding "Kunitz domain" proteins and analogues thereof |
| DE69533544T2 (de) * | 1994-01-11 | 2006-02-23 | Dyax Corp., Cambridge | Inhibitoren des humanplasmins, die sich von den kunitz domänen ableiten |
| US5795954A (en) * | 1994-03-04 | 1998-08-18 | Genentech, Inc. | Factor VIIa inhibitors from Kunitz domain proteins |
| US5589359A (en) * | 1994-08-05 | 1996-12-31 | Chiron Corporation | Chimeric proteins |
| DE19507166C1 (de) | 1995-03-01 | 1996-04-18 | Deutsches Krebsforsch | Antikörper gegen ein Histidin-Fusionspolypeptid, das einen Histidin-Anteil aufweist |
| US5786328A (en) * | 1995-06-05 | 1998-07-28 | Genentech, Inc. | Use of kunitz type plasma kallikrein inhibitors |
| CN1200036A (zh) * | 1995-09-14 | 1998-11-25 | Lxr生物技术有限公司 | 含有磷脂混合物并具有抗细胞程序死亡活性的组合物 |
| US5770265A (en) * | 1995-09-26 | 1998-06-23 | Triangle Laboratories, Inc. | Environmentally friendly treatments to extend the functional life of wood structures and novel treated wood structures |
| US5736364A (en) * | 1995-12-04 | 1998-04-07 | Genentech, Inc. | Factor viia inhibitors |
| US6017723A (en) * | 1998-03-27 | 2000-01-25 | Long Island Jewish Medical Center | Method for isolating inhibitors of protease activity |
| WO1999051773A1 (en) | 1998-04-03 | 1999-10-14 | Phylos, Inc. | Addressable protein arrays |
| US6190908B1 (en) * | 1998-08-12 | 2001-02-20 | The Scripps Research Institute | Modulation of polypeptide display on modified filamentous phage |
| JP3763505B2 (ja) | 1998-09-22 | 2006-04-05 | Tdk株式会社 | 薄膜磁気ヘッドの製造方法 |
| US6472147B1 (en) | 1999-05-25 | 2002-10-29 | The Scripps Research Institute | Methods for display of heterodimeric proteins on filamentous phage using pVII and pIX, compositions, vectors and combinatorial libraries |
| PT1144607E (pt) | 1999-07-20 | 2009-04-22 | Morphosys Ag | Novos métodos para apresentar (poli)peptídeos/ proteínas em partículas bacteriofágicas através de ligações dissulfureto |
| GB9928787D0 (en) | 1999-12-03 | 2000-02-02 | Medical Res Council | Direct screening method |
| CA2434139C (en) | 2001-01-23 | 2014-05-27 | President And Fellows Of Harvard College | Nucleic-acid programmable protein arrays |
| ES2327905T3 (es) | 2001-10-01 | 2009-11-05 | Dyax Corp. | Vectores de presentacion eucariotas multi-cadena y usos de los mismos. |
| US20030129659A1 (en) | 2001-12-03 | 2003-07-10 | Whelihan E. Fayelle | Library screening |
-
2004
- 2004-01-07 WO PCT/US2004/000333 patent/WO2004063337A2/en not_active Ceased
- 2004-01-07 DK DK04700617.6T patent/DK1587907T3/da active
- 2004-01-07 JP JP2006500832A patent/JP2007524348A/ja active Pending
- 2004-01-07 PT PT04700617T patent/PT1587907E/pt unknown
- 2004-01-07 DE DE602004031589T patent/DE602004031589D1/de not_active Expired - Lifetime
- 2004-01-07 EP EP04700617A patent/EP1587907B1/en not_active Expired - Lifetime
- 2004-01-07 EP EP10012620A patent/EP2290107A1/en not_active Withdrawn
- 2004-01-07 ES ES04700617T patent/ES2362424T3/es not_active Expired - Lifetime
- 2004-01-07 AU AU2004204095A patent/AU2004204095B2/en not_active Ceased
- 2004-01-07 US US10/753,544 patent/US20040209243A1/en not_active Abandoned
- 2004-01-07 CA CA002512590A patent/CA2512590A1/en not_active Abandoned
- 2004-01-07 AT AT04700617T patent/ATE500345T1/de active
-
2007
- 2007-07-09 US US11/774,964 patent/US20080020394A1/en not_active Abandoned
-
2010
- 2010-02-22 JP JP2010036225A patent/JP2010162030A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATE500345T1 (de) | 2011-03-15 |
| JP2010162030A (ja) | 2010-07-29 |
| WO2004063337A3 (en) | 2007-01-25 |
| PT1587907E (pt) | 2011-04-08 |
| JP2007524348A (ja) | 2007-08-30 |
| WO2004063337A2 (en) | 2004-07-29 |
| EP1587907A4 (en) | 2007-11-14 |
| DK1587907T3 (da) | 2011-04-04 |
| US20040209243A1 (en) | 2004-10-21 |
| CA2512590A1 (en) | 2004-07-29 |
| ES2362424T3 (es) | 2011-07-05 |
| AU2004204095A1 (en) | 2004-07-29 |
| US20080020394A1 (en) | 2008-01-24 |
| AU2004204095B2 (en) | 2009-07-30 |
| EP1587907B1 (en) | 2011-03-02 |
| EP2290107A1 (en) | 2011-03-02 |
| EP1587907A2 (en) | 2005-10-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE500345T1 (de) | Kunitz-domäne-bibliothek | |
| DE602004029323D1 (de) | Verfahren und System zum Auswählen und Manipulieren von mehreren Objekten | |
| DK1576582T3 (da) | Kodning af multiple meddelelser i lyddata og detektere samme | |
| DE602004023441D1 (de) | Medienzugriffskontrolle in Master-Slave Systemen | |
| DE60329299D1 (de) | Tragbares informationsendgerät, programm und aufzeichnungsmedium mit dem darin aufgezeichneten programm | |
| EP1661115A4 (en) | COMPUTER MOUSE WITH DATA CALLING AND INPUT FUNCTIONALITIES | |
| DE602006001687D1 (de) | Magnetoresistive Vorrichtung und Magnetspeicher damit | |
| AU2003287663A1 (en) | Mram and methods for reading the mram | |
| EP1634142A4 (en) | Computer systems and methods for the query and visualization of multidimensional databases | |
| SG109545A1 (en) | Storing data to magnetic tape both to one set of tracks and in the same operation rewritten to another set of tracks | |
| DE602004022679D1 (de) | Schnelle anwendungsbenachrichtigung in einem geclusterten rechnersystem | |
| DE60114811D1 (de) | Datenverarbeitungsgerät, graphische verarbeitungseinrichtung, graphische verarbeitungsverfahren, speichermedium, und computerprogramm | |
| DE602004003860D1 (de) | Spielvorrichtung und Spielprogramm auf Speichermedium | |
| DE60044423D1 (de) | Verfahren und Gerät zum Wiederauffinden und Ausgeben von Dokumenten und Speichermedium mit entspechendem Program | |
| WO2007078645A3 (en) | Method and apparatus for cloning filesystems across computing systems | |
| WO2004017181A3 (en) | Computer-aided education systems and methods | |
| DE602006019937D1 (de) | Host-Gerät und denselben benutzendes Informationsverarbeitungssystem | |
| DE60138152D1 (de) | Unterhaltungsgerät, Aufzeichnungsmedium und Rechnerprogramm | |
| DE602004017631D1 (de) | Speichersystem und Computersystem | |
| DE602004001679D1 (de) | Speichersystem mit sequenziell ausgeführten schnellen und langsamen lesezugriffen | |
| Du Cloux | Rigidity of Schubert closures and invariance of Kazhdan–Lusztig polynomials | |
| SE0301248D0 (sv) | Methods, apparatus, computer program and storage medium for position decoding | |
| BR8200934Y1 (pt) | disposição construtiva introduzida em porta cd e similar. | |
| JP2007127736A5 (enExample) | ||
| ATE383489T1 (de) | Tür mit versetzter drehachse |