JP2009521931A - 胎盤幹細胞を収集及び保存するための改善された組成物、及び該組成物の使用方法 - Google Patents

胎盤幹細胞を収集及び保存するための改善された組成物、及び該組成物の使用方法 Download PDF

Info

Publication number
JP2009521931A
JP2009521931A JP2008548747A JP2008548747A JP2009521931A JP 2009521931 A JP2009521931 A JP 2009521931A JP 2008548747 A JP2008548747 A JP 2008548747A JP 2008548747 A JP2008548747 A JP 2008548747A JP 2009521931 A JP2009521931 A JP 2009521931A
Authority
JP
Japan
Prior art keywords
alkyl
aryl
stem cell
composition
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2008548747A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009521931A5 (cg-RX-API-DMAC7.html
Inventor
ダブリュー．エディンゲル ジャメス
ヘイダラン モハマド
ホフガルトネル ウォルフガング
Original Assignee
アントフロゲネシス コーポレーション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アントフロゲネシス コーポレーション filed Critical アントフロゲネシス コーポレーション
Publication of JP2009521931A publication Critical patent/JP2009521931A/ja
Publication of JP2009521931A5 publication Critical patent/JP2009521931A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/48—Regulators of apoptosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
JP2008548747A 2005-12-29 2006-12-28 胎盤幹細胞を収集及び保存するための改善された組成物、及び該組成物の使用方法 Pending JP2009521931A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75496905P 2005-12-29 2005-12-29
PCT/US2006/049493 WO2007079185A2 (en) 2005-12-29 2006-12-28 Improved composition for collecting and preserving placental stem cells and methods of using the composition

Publications (2)

Publication Number Publication Date
JP2009521931A true JP2009521931A (ja) 2009-06-11
JP2009521931A5 JP2009521931A5 (cg-RX-API-DMAC7.html) 2010-02-18

Family

ID=38228854

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008548747A Pending JP2009521931A (ja) 2005-12-29 2006-12-28 胎盤幹細胞を収集及び保存するための改善された組成物、及び該組成物の使用方法

Country Status (11)

Country Link
US (4) US9598669B2 (cg-RX-API-DMAC7.html)
EP (1) EP1974013A2 (cg-RX-API-DMAC7.html)
JP (1) JP2009521931A (cg-RX-API-DMAC7.html)
KR (1) KR20080097190A (cg-RX-API-DMAC7.html)
CN (1) CN101374941A (cg-RX-API-DMAC7.html)
AU (1) AU2006332680A1 (cg-RX-API-DMAC7.html)
CA (1) CA2633980A1 (cg-RX-API-DMAC7.html)
IL (1) IL191771A (cg-RX-API-DMAC7.html)
PE (1) PE20071015A1 (cg-RX-API-DMAC7.html)
WO (1) WO2007079185A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200804717B (cg-RX-API-DMAC7.html)

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012014911A1 (ja) * 2010-07-30 2012-02-02 株式会社 バイオリンクインク 細胞分離用酵素溶液及び細胞分離方法、並びに膵島分離方法
WO2012063870A1 (ja) * 2010-11-09 2012-05-18 株式会社大塚製薬工場 幹細胞懸濁液
JP2013223504A (ja) * 2010-11-09 2013-10-31 Otsuka Pharmaceut Factory Inc 細胞生存率低下抑制剤
JP2013233102A (ja) * 2012-05-08 2013-11-21 Otsuka Pharmaceut Factory Inc トレハロース含有肺塞栓形成予防用哺乳動物細胞懸濁液
JP2014517821A (ja) * 2011-04-14 2014-07-24 トランスメディクス，インコーポレイテッド ドナー肺のＥｘ−ｖｉｖｏにおける機械的灌流のための臓器保護溶液
JP2016520550A (ja) * 2013-04-05 2016-07-14 ジルバーバーグ，クラウディア マトリクスメタロプロテイナーゼおよびその使用
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US9516875B2 (en) 2008-01-31 2016-12-13 Transmedics, Inc. Systems and methods for ex vivo lung care
US9756851B2 (en) 1997-09-23 2017-09-12 The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US9894894B2 (en) 2004-10-07 2018-02-20 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US10039276B2 (en) 2005-06-28 2018-08-07 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US10076112B2 (en) 2014-06-02 2018-09-18 Transmedic, Inc. Ex vivo organ care system
US10194655B2 (en) 2015-09-09 2019-02-05 Transmedics, Inc. Aortic cannula for ex vivo organ care system
US10314303B2 (en) 2004-10-07 2019-06-11 Transmedics, Inc. Systems and methods for ex-vivo organ care
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status

Families Citing this family (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7311905B2 (en) * 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
KR100915482B1 (ko) 2000-12-06 2009-09-03 하리리 로버트 제이 태반 줄기 세포의 회수 방법
ES2548591T3 (es) 2001-02-14 2015-10-19 Anthrogenesis Corporation Placenta post-parto de mamífero, su uso y células madre placentarias de la misma
EP2336299A1 (en) 2001-02-14 2011-06-22 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
US7498171B2 (en) * 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
BR0316695A (pt) * 2002-11-26 2005-10-18 Anthrogenesis Corp Unidade citoterapêutica, kit para tratamento, método de tratamento de uma enfermidade, biblioteca de unidades citoterapêuticas e método de tratamento de um paciente
NZ550027A (en) * 2004-03-26 2009-03-31 Celgene Corp Systems and methods for providing a stem cell bank
JP5203212B2 (ja) * 2005-10-13 2013-06-05 アントフロゲネシス コーポレーション 胎盤由来幹細胞からのオリゴデンドロサイトの産生
MX343814B (es) 2005-10-13 2016-11-24 Anthrogenesis Corp Inmunomodulación usando celulas madre de la placenta.
US20070269863A1 (en) * 2005-12-22 2007-11-22 Bridon Dominique P Process for the production of preformed conjugates of albumin and a therapeutic agent
JP2009521931A (ja) 2005-12-29 2009-06-11 アントフロゲネシス コーポレーション 胎盤幹細胞を収集及び保存するための改善された組成物、及び該組成物の使用方法
EP2471903B1 (en) 2005-12-29 2018-02-14 Anthrogenesis Corporation Placental stem cell populations
EP1976978A2 (en) * 2005-12-29 2008-10-08 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
US7993918B2 (en) * 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
EP2418271A3 (en) 2006-10-23 2015-09-30 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
CN101657206B (zh) 2007-02-12 2013-07-03 人类起源公司 利用胎盘干细胞治疗炎性疾病
JP2010518812A (ja) 2007-02-12 2010-06-03 アンスロジェネシス コーポレーション 接着性胎盤幹細胞由来の肝細胞および軟骨細胞、ならびにｃｄ３４＋、ｃｄ４５−胎盤幹細胞の濃縮細胞集団
CA2688504A1 (en) 2007-06-18 2008-12-24 Children's Hospital & Research Center At Oakland Method of isolating stem and progenitor cells from placenta
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
WO2009021333A1 (en) * 2007-08-14 2009-02-19 Tissue Regeneration Therapeutics Inc. Blood vessel extraction from umbilical cord
CA2736663C (en) 2007-09-07 2018-01-02 Surgical Biologics, Llc. Placental tissue grafts and improved methods of preparing and using the same
CN101878034B (zh) 2007-09-28 2013-11-20 细胞基因细胞疗法公司 使用人胎盘灌洗液和人来自胎盘的中间体自然杀伤细胞的肿瘤抑制
PT103843B (pt) * 2007-10-04 2008-08-12 Medinfar Produtos Farmaceutico Método de isolamento de células precursoras a partir do cordão umbilical humano
MX2010000393A (es) * 2007-11-09 2010-05-19 Rnl Bio Co Ltd Metodo para el aislamiento y cultivo de celulas madre adultas derivadas del epitelio amniotico humano.
US8344018B2 (en) 2008-07-14 2013-01-01 Gilead Sciences, Inc. Oxindolyl inhibitor compounds
JP5950577B2 (ja) 2008-08-20 2016-07-13 アンスロジェネシス コーポレーション 単離胎盤細胞を使用した脳卒中の治療
KR20240052847A (ko) 2008-08-20 2024-04-23 셀룰래리티 인코포레이티드 개선된 세포 조성물 및 그의 제조 방법
US8728805B2 (en) 2008-08-22 2014-05-20 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
WO2010026574A2 (en) * 2008-09-02 2010-03-11 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
WO2010040262A1 (zh) * 2008-10-10 2010-04-15 深圳市嘉天源生物科技有限公司 分离动物胚胎间质性干细胞并提取其分泌物的方法
NZ592726A (en) 2008-11-19 2012-12-21 Anthrogenesis Corp Amnion derived adherent cells
MX2011005230A (es) 2008-11-21 2011-06-16 Anthrogenesis Corp Tratamiento de enfermedades, desordenes o condiciones del pulmon usando celulas de placenta.
US8771677B2 (en) 2008-12-29 2014-07-08 Vladimir B Serikov Colony-forming unit cell of human chorion and method to obtain and use thereof
CA3110964A1 (en) 2009-03-25 2010-09-30 Xiaokui Zhang Preventing a symptom of graft-versus-host disease using human placenta-derived intermediate natural killer cells
US20100323446A1 (en) 2009-06-05 2010-12-23 Jill Renee Barnett Method of collecting placental cells
US8258316B2 (en) 2009-06-08 2012-09-04 Gilead Sciences, Inc. Alkanoylamino benzamide aniline HDAC inhibitor compounds
US8283357B2 (en) 2009-06-08 2012-10-09 Gilead Sciences, Inc. Cycloalkylcarbamate benzamide aniline HDAC inhibitor compounds
AR077369A1 (es) 2009-07-02 2011-08-24 Anthrogenesis Corp Metodopara producir eritrocitos sin celulas alimentadoras
ES2646750T3 (es) 2010-01-26 2017-12-15 Anthrogenesis Corporation Tratamiento de cánceres relacionados con hueso utilizando células madre placentarias
LT2556145T (lt) 2010-04-07 2016-11-10 Anthrogenesis Corporation Angiogenezė naudojant placentos kamienines ląsteles
MX2012011543A (es) 2010-04-08 2013-05-06 Anthrogenesis Corp Tratamiento de sarcoidosis empleando celulas madre placentarias.
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
JP5996533B2 (ja) 2010-07-13 2016-09-21 アントフロゲネシス コーポレーション ナチュラルキラー細胞を生成させる方法
DE102010034330B4 (de) * 2010-08-14 2013-10-31 Cytonet Gmbh & Co. Kg Verfahren zur Herstellung desinfizierter humaner Zellsuspensionen
US8574899B2 (en) 2010-12-22 2013-11-05 Vladimir B Serikov Methods for augmentation collection of placental hematopoietic stem cells and uses thereof
WO2012092480A1 (en) 2010-12-30 2012-07-05 Anthirogenesis Corporation Compositions comprising amnion derived adherent cells and platelet-rich plasma
AR084754A1 (es) 2010-12-30 2013-06-05 Anthrogenesis Corp Composiciones que comprenden celulas madre de placenta y plasma rico en plaquetas, y sus metodos de uso
US8969315B2 (en) 2010-12-31 2015-03-03 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory RNA molecules
EP2714059B1 (en) 2011-06-01 2018-10-03 Celularity, Inc. Treatment of pain using placental stem cells
RU2491337C2 (ru) * 2011-06-09 2013-08-27 Елена Владимировна Орлова Средство и способы культивирования, хранения и криоконсервации стволовых и дифференцированных клеток человека и животных
US10190092B2 (en) 2011-08-11 2019-01-29 Robert A. Dracker Procurement of placental stem cells
WO2013023212A2 (en) * 2011-08-11 2013-02-14 Dracker Robert A Procurement of placental stem cells
US9925221B2 (en) 2011-09-09 2018-03-27 Celularity, Inc. Treatment of amyotrophic lateral sclerosis using placental stem cells
WO2013110094A1 (en) * 2012-01-17 2013-07-25 Dracker Robert A Procurement of placental stem cells and umbilical cord segments
CN114134113A (zh) 2012-08-13 2022-03-04 人类起源公司 自然杀伤细胞及其用途
CN113481164A (zh) 2012-12-14 2021-10-08 人类起源公司 抗失巢凋亡胎盘干细胞及其应用
AU2013204922B2 (en) 2012-12-20 2015-05-14 Celgene Corporation Chimeric antigen receptors
US9763983B2 (en) 2013-02-05 2017-09-19 Anthrogenesis Corporation Natural killer cells from placenta
DK2970883T3 (da) 2013-03-14 2021-08-09 Celularity Inc Forbedrede placenta stamceller og bruge deraf
CN103756965B (zh) * 2014-01-27 2016-04-06 山东省齐鲁干细胞工程有限公司 一种从胎盘中灌洗造血干细胞的方法
CN104357396A (zh) * 2014-11-03 2015-02-18 赛欧帕克（江苏）干细胞生物工程有限公司 一种提取早期造血前体干细胞的方法及其应用
DK3229588T3 (da) 2014-12-12 2025-06-23 Transmedics Inc Anordning og fremgangsmåde til organperfusion
US10542743B2 (en) * 2015-01-05 2020-01-28 Hygieia Therapeutics Sdn Bhd Isolation, expansion and characterization of wharton's jelly mesenchymal stem cells
CN104711226B (zh) * 2015-04-09 2018-09-21 广州赛莱拉干细胞科技股份有限公司 一种胎盘造血干细胞的制备方法
CN104774806B (zh) * 2015-04-09 2019-02-15 广州赛莱拉干细胞科技股份有限公司 一种胎盘造血干细胞的制备方法
WO2016187413A1 (en) 2015-05-21 2016-11-24 Musculoskeletal Transplant Foundation Modified demineralized cortical bone fibers
SG10201912572VA (en) 2015-09-15 2020-02-27 Celularity Inc Treatment of diabetic peripheral neuropathy using placental cells
EP3360957A4 (en) * 2015-10-08 2019-03-13 Kaohsiung Medical University COMPOSITION FOR THE QUICK SEPARATION OF CELLS FROM FAT
RU2710554C1 (ru) 2016-02-19 2019-12-27 Интерконтинентал Грейт Брендс Ллк Способы образования множества ценных потоков из источников на основе биомассы
CN105695302B (zh) * 2016-03-14 2018-07-24 广州赛莱拉干细胞科技股份有限公司 一种离体胎盘造血干细胞的制备方法
DK3462861T5 (da) 2016-05-30 2024-01-08 Transmedics Inc Fremgangsmåde til ex vivo-lungeventilati on med et varierende udvendigt tryk
EP3548051A1 (en) 2016-12-05 2019-10-09 Celularity, Inc. Treatment of lymphedema and related conditions using placental adherent cells
TWI793151B (zh) 2017-08-23 2023-02-21 瑞士商諾華公司 3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
JP7458324B2 (ja) 2018-04-23 2024-03-29 セルジーン コーポレイション 置換された４－アミノイソインドリン－１，３－ジオン化合物、及びリンパ腫の治療のためのそれらの使用
AR116109A1 (es) 2018-07-10 2021-03-31 Novartis Ag Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
CR20210001A (es) 2018-07-10 2021-04-19 Novartis Ag Derivados de 3-(5-hidroxi-1-oxoisoindolin-2-il)piperidina-2,6-diona y su uso en el tratamiento de trastornos dependientes de la proteina con dedos de zinc 2 de la familia ikaros (1kzf2)
US11116206B2 (en) 2018-10-01 2021-09-14 Cook Medical Technologies Llc Cryocontainer
JP2022507267A (ja) 2018-11-13 2022-01-18 バイオセリックス， インコーポレイテッド 置換イソインドリノン
SG11202105213XA (en) 2018-11-30 2021-06-29 Celularity Inc Expansion of natural killer cells and ilc3 cells with novel aromatic compounds
JP2022519690A (ja) * 2019-02-05 2022-03-24 リンディー バイオサイエンシーズ，インク． 単離された細胞培養成分、及びそれを液状の細胞培養培地から単離する方法
WO2020252464A1 (en) 2019-06-14 2020-12-17 Celularity Inc. Populations of natural killer cells for treating cancers
US20220273716A1 (en) 2019-07-25 2022-09-01 Celularity Inc. Populations of natural killer cells comprising a cd38 chimeric antigen receptor
US20230355759A1 (en) 2019-07-31 2023-11-09 Celularity Inc. Populations of natural killer cells comprising a cleavage resistant cd16
WO2021113849A1 (en) 2019-12-05 2021-06-10 Celularity Inc. Her2+ cancer treatment with populations of natural killer cells comprising a cleavage resistant cd16
US20220000919A1 (en) 2020-01-29 2022-01-06 Celularity Inc. Placental derived natural killer cells for treatment of coronavirus infections
WO2021226602A1 (en) 2020-05-08 2021-11-11 Celularity Inc. Placenta-derived adherent (pda) stem cell for the treatment of adults with sars-cov-2 related acute respiratory failure and ards (covid-19)
CN111700063B (zh) * 2020-06-29 2021-03-30 广州瑞铂茵健康科技有限公司 一种脐带标本的保存方法
CN112941009B (zh) * 2021-02-22 2024-03-01 新格元(南京)生物科技有限公司 一种ffpe样本预处理液及从ffpe样本中分离单细胞的方法
WO2023278628A1 (en) 2021-06-29 2023-01-05 Celularity Inc. Human placental hematopoietic stem cell derived natural killer cells in acute myeloid leukemia (aml) remission with minimal residual disease (mrd) or relapsed/refractory aml
CR20240104A (es) 2021-07-29 2024-06-28 Celularity Inc Células NK derivadas de la placenta como senolítico para usos terapéuticos y otros.
US12471592B2 (en) 2021-08-18 2025-11-18 Reelabs Private Limited Cytoprotective compositions for short-term cells storage and transportation without cryopreservation and deep freezing
CA3247919A1 (en) 2022-01-11 2023-07-20 Celularity Inc. CD16 CLEFT-RESISTANT CONSTRUCTIONS AND THEIR USES

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001503384A (ja) * 1996-07-24 2001-03-13 セルジーン コーポレイション 置換２―（２，６―ジオキソピペリジン―３―イル）フタルイミド類及び―１―オキソイソインドリン類ならびにＴＮＦαレベルの減少方法
JP2002501536A (ja) * 1997-05-30 2002-01-15 セルジーン コーポレイション 置換２−（２，６−ジオキソピペリジン−３−イル）−フタルイミド類及び１−オキソイソインドリン類ならびにＴＮＦαレベルの減少方法
WO2003087392A2 (en) * 2002-04-12 2003-10-23 Celgene Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
WO2004035064A1 (en) * 2002-10-15 2004-04-29 Celgene Corporation Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of myelodysplastic syndromes
WO2004043377A2 (en) * 2002-11-06 2004-05-27 Celgene Corporation Methods and compositions using immunomodulatory compounds for treatment and management of cancers and other diseases
WO2004043464A1 (en) * 2002-11-06 2004-05-27 Celgene Corporation Methods of using and compositions comprising immunomudulatory compounds for the treatment and management of myeloproliferative diseases
JP2004528021A (ja) * 2001-02-14 2004-09-16 アンスロジェネシス コーポレーション 分娩後の哺乳動物の胎盤、その使用およびそれに由来する胎盤幹細胞
WO2005003334A2 (en) * 2003-06-27 2005-01-13 Ethicon, Incorporated Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
JP2005522215A (ja) * 2002-04-12 2005-07-28 セルジーン・コーポレーション 幹細胞及び前駆細胞の分化のモジュレーション、アッセイ、並びにそれらの使用
JP2005528105A (ja) * 2002-05-30 2005-09-22 セルジーン・コーポレーション 細胞分化をモジュレートするため、並びに骨髄増殖性疾患及び骨髄異形成症候群を治療するためのｊｎｋ又はｍｋｋ阻害剤の使用方法

Family Cites Families (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4798824A (en) 1985-10-03 1989-01-17 Wisconsin Alumni Research Foundation Perfusate for the preservation of organs
US5197985A (en) 1990-11-16 1993-03-30 Caplan Arnold I Method for enhancing the implantation and differentiation of marrow-derived mesenchymal cells
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5552267A (en) 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5698579A (en) 1993-07-02 1997-12-16 Celgene Corporation Cyclic amides
US5635517B1 (en) 1996-07-24 1999-06-29 Celgene Corp Method of reducing TNFalpha levels with amino substituted 2-(2,6-dioxopiperidin-3-YL)-1-oxo-and 1,3-dioxoisoindolines
US5798368A (en) 1996-08-22 1998-08-25 Celgene Corporation Tetrasubstituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines and method of reducing TNFα levels
US6281230B1 (en) 1996-07-24 2001-08-28 Celgene Corporation Isoindolines, method of use, and pharmaceutical compositions
SK17799A3 (en) 1996-08-12 1999-11-08 Celgene Corp Cyano and carboxy derivatives of substituted styrenes, pharmaceutical composition containing same and their use
US6497890B2 (en) * 1996-12-03 2002-12-24 Parvin Youssefyeh Anti-wrinkle preparation and method of reducing wrinkles in facial skin and neck
CA2242648A1 (en) * 1997-07-10 1999-01-10 Kyowa Hakko Kogyo Co., Ltd. Method of reconstructing animal organs
US5874448A (en) 1997-11-18 1999-02-23 Celgene Corporation Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNFα levels
US5955476A (en) 1997-11-18 1999-09-21 Celgene Corporation Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels
US20010055809A1 (en) * 1998-01-30 2001-12-27 Harpal S. Mangat Extending tissue preservation
TR200101500T2 (tr) 1998-03-16 2002-06-21 Celgene Corporation 2-(2,6-dioksopiperidin-3-il)izoindolin türevleri, bunların hazırlanması ve enflamatuarn sitokinlerin inhibitörleri olarak kullanımı.
CA2341718A1 (en) 1998-08-28 2000-03-09 Neil H. Baine An improved synthesis of 3-hydroxy-4-amino-benzonitrile
CA2354402A1 (en) 1998-12-17 2000-06-22 F. Hoffmann-La Roche Ag 4,5-pyrazinoxindoles as protein kinase inhibitors
JP2002532493A (ja) 1998-12-17 2002-10-02 エフ．ホフマン−ラ ロシュ アーゲー Ｊｎｋプロテインキナーゼ阻害剤としての４−アリールオキシインドール
US6288089B1 (en) 1998-12-21 2001-09-11 Michael Zawada Use of kinase inhibitors for treating neurodegenerative diseases
GB9828511D0 (en) 1998-12-24 1999-02-17 Zeneca Ltd Chemical compounds
NZ513953A (en) 1999-03-18 2001-09-28 Celgene Corp Substituted 1-oxo- and 1,3-dioxoisoindolines and their use in pharmaceutical compositions for reducing inflammatory cytokine levels
GB9906566D0 (en) 1999-03-23 1999-05-19 Zeneca Ltd Chemical compounds
WO2000064872A1 (en) 1999-04-23 2000-11-02 Vertex Pharmaceuticals Incorporated INHIBITORS OF c-JUN N-TERMINAL KINASES (JNK)
WO2000073421A2 (en) 1999-06-02 2000-12-07 Lifebank Services, L.L.C. Methods of isolation, cryopreservation, and therapeutic use of human amniotic epithelial cells
WO2000075118A1 (en) 1999-06-03 2000-12-14 Vertex Pharmaceuticals Incorporated INHIBITORS OF c-JUN N-TERMINAL KINASES (JNK)
NZ517694A (en) 1999-08-13 2005-03-24 Vertex Pharma Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases
WO2001012609A1 (en) 1999-08-19 2001-02-22 Signal Pharmaceuticals, Inc. Pyrazoloanthrone and derivatives thereof as jnk inhibitors and their compositions
US7119114B1 (en) 1999-08-19 2006-10-10 Signal Pharmaceuticals, Llc Pyrazoloanthrone and derivatives thereof as JNK inhibitors and compositions and methods related thereto
US20040072888A1 (en) 1999-08-19 2004-04-15 Bennett Brydon L. Methods for treating inflammatory conditions or inhibiting JNK
GB9919778D0 (en) 1999-08-21 1999-10-27 Zeneca Ltd Chemical compounds
EP1088821A1 (en) 1999-09-28 2001-04-04 Applied Research Systems ARS Holding N.V. Pharmaceutically active sulfonamide derivatives
GB9924092D0 (en) 1999-10-13 1999-12-15 Zeneca Ltd Pyrimidine derivatives
AU1082901A (en) * 1999-10-18 2001-04-30 National Jewish Medical And Research Center Method for modulation of cell phenotype
US6428785B1 (en) * 1999-10-28 2002-08-06 Immunolytics Inc. Method and composition for treating prostate cancer
EP1110957A1 (en) 1999-12-24 2001-06-27 Applied Research Systems ARS Holding N.V. Benzazole derivatives and their use as JNK modulators
IL145756A0 (en) 2000-02-05 2002-07-25 Vertex Pharma Pyrazole derivatives and pharmaceutical compositions containing the same
WO2001058448A1 (fr) 2000-02-09 2001-08-16 Shionogi & Co., Ltd. Inhibiteur d'apoptose
CA2410475A1 (en) 2000-06-01 2001-12-06 Merck & Co., Inc. Use of (di-substituted-phenyl)-pyrimidinyl-imidazole derivatives as jnk-inhibitors
US6897231B2 (en) 2000-07-31 2005-05-24 Signal Pharmaceuticals, Inc. Indazole derivatives as JNK inhibitors and compositions and methods related thereto
US20050009876A1 (en) 2000-07-31 2005-01-13 Bhagwat Shripad S. Indazole compounds, compositions thereof and methods of treatment therewith
US7211594B2 (en) 2000-07-31 2007-05-01 Signal Pharmaceuticals, Llc Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith
PE20020506A1 (es) 2000-08-22 2002-07-09 Glaxo Group Ltd Derivados de pirazol fusionados como inhibidores de la proteina cinasa
US6458810B1 (en) 2000-11-14 2002-10-01 George Muller Pharmaceutically active isoindoline derivatives
US7129242B2 (en) 2000-12-06 2006-10-31 Signal Pharmaceuticals, Llc Anilinopyrimidine derivatives as JNK pathway inhibitors and compositions and methods related thereto
US7429599B2 (en) 2000-12-06 2008-09-30 Signal Pharmaceuticals, Llc Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
KR100915482B1 (ko) 2000-12-06 2009-09-03 하리리 로버트 제이 태반 줄기 세포의 회수 방법
US20080152629A1 (en) 2000-12-06 2008-06-26 James Edinger Placental stem cell populations
US7122544B2 (en) 2000-12-06 2006-10-17 Signal Pharmaceuticals, Llc Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto
US7091353B2 (en) 2000-12-27 2006-08-15 Celgene Corporation Isoindole-imide compounds, compositions, and uses thereof
US20030045552A1 (en) 2000-12-27 2003-03-06 Robarge Michael J. Isoindole-imide compounds, compositions, and uses thereof
ES2548591T3 (es) 2001-02-14 2015-10-19 Anthrogenesis Corporation Placenta post-parto de mamífero, su uso y células madre placentarias de la misma
US6987184B2 (en) 2001-02-15 2006-01-17 Signal Pharmaceuticals, Llc Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof as JNK inhibitors and compositions and methods related
EP1370644A4 (en) * 2001-02-28 2007-07-25 Henry M Jackson Foundation MATERIALS AND METHODS FOR ACTIVATING PREMATURE CHROMOSOMAL CONDENSATION
DE10139783C1 (de) 2001-08-14 2003-04-17 Transtissue Technologies Gmbh Zellzusammensetzungen zur Behandlung von Osteoarthrose, sowie Verfahren zu deren Herstellung
US7799324B2 (en) 2001-12-07 2010-09-21 Geron Corporation Using undifferentiated embryonic stem cells to control the immune system
NZ534643A (en) 2002-02-13 2010-06-25 Anthrogenesis Corp Embryonic-like stem cells derived from post-partum mammalian placenta and uses and methods of treatment using said cells
US20030187515A1 (en) 2002-03-26 2003-10-02 Hariri Robert J. Collagen biofabric and methods of preparing and using the collagen biofabric
MXPA04009996A (es) * 2002-04-12 2005-07-01 Celgene Corp Metodos para la identificacion de moduladores de la angiogenesis, compuestos descubiertos por los mismos, y metodos de tratamiento usando los compuestos.
EP1545509A4 (en) * 2002-09-25 2008-10-22 Univ Rochester CASPASE HEMMER AS CANCER
BR0316695A (pt) 2002-11-26 2005-10-18 Anthrogenesis Corp Unidade citoterapêutica, kit para tratamento, método de tratamento de uma enfermidade, biblioteca de unidades citoterapêuticas e método de tratamento de um paciente
CA2515594A1 (en) 2003-02-13 2004-08-26 Anthrogenesis Corporation Use of umbilical cord blood to treat individuals having a disease, disorder or condition
US20050153887A1 (en) * 2003-10-24 2005-07-14 California Institute Of Technology Compositions for inducing cell growth and differentiation and methods of using same
EP2065383A1 (en) 2003-11-19 2009-06-03 Signal Pharmaceuticals, Inc. Indazole compounds and methods of use thereof as protein kinase inhibitors
EP1694328A4 (en) 2003-12-02 2010-02-17 Celgene Corp METHOD AND COMPOSITIONS FOR THE TREATMENT AND SUPPLY OF HEMOGLOBINOPATHY AND ANEMIA
WO2005056763A2 (en) * 2003-12-04 2005-06-23 University Of Utah Research Foundation Process and formulation to improve viability of stored cells and tissue
US20050233446A1 (en) * 2003-12-31 2005-10-20 Parsons Xuejun H Defined media for stem cell culture
US20050266391A1 (en) 2004-01-15 2005-12-01 Bennett Brydon L Methods for preserving tissue
NZ550027A (en) 2004-03-26 2009-03-31 Celgene Corp Systems and methods for providing a stem cell bank
US7244759B2 (en) 2004-07-28 2007-07-17 Celgene Corporation Isoindoline compounds and methods of making and using the same
US7147626B2 (en) 2004-09-23 2006-12-12 Celgene Corporation Cord blood and placenta collection kit
US7909806B2 (en) 2004-09-23 2011-03-22 Anthrogenesis Corporation Cord blood and placenta collection kit
BRPI0518255A2 (pt) 2004-11-23 2008-11-11 Celgene Corp mÉtodos de tratamento ou prevenÇço de uma lesço do sistema nervoso central, para reduzir ou evitar um efeito adverso, e composiÇço farmacÊutica
EP1893249A2 (en) 2005-06-10 2008-03-05 Celgene Corporation Human placental collagen compositions, processes for their preparation, methods of their use and kits comprising the compositions
WO2007005807A2 (en) 2005-06-30 2007-01-11 Anthrogenesis Corporation Repair of tympanic membrane using placenta derived collagen biofabric
WO2007009062A2 (en) 2005-07-13 2007-01-18 Anthrogenesis Corporation Treatment of leg ulcers using placenta derived collagen biofabric
US20070021762A1 (en) 2005-07-13 2007-01-25 Qing Liu Ocular plug formed from placenta derived collagen biofabric
US20070065414A1 (en) * 2005-09-16 2007-03-22 Boston Scientific Scimed, Inc. Enhanced delivery of cells
JP5203212B2 (ja) 2005-10-13 2013-06-05 アントフロゲネシス コーポレーション 胎盤由来幹細胞からのオリゴデンドロサイトの産生
MX343814B (es) 2005-10-13 2016-11-24 Anthrogenesis Corp Inmunomodulación usando celulas madre de la placenta.
JP2009521931A (ja) 2005-12-29 2009-06-11 アントフロゲネシス コーポレーション 胎盤幹細胞を収集及び保存するための改善された組成物、及び該組成物の使用方法
EP2471903B1 (en) 2005-12-29 2018-02-14 Anthrogenesis Corporation Placental stem cell populations
EP1976978A2 (en) 2005-12-29 2008-10-08 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
EP2035552A2 (en) 2006-06-09 2009-03-18 Anthrogenesis Corporation Placental niche and use thereof to culture stem cells
US7993918B2 (en) 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
US8105634B2 (en) 2006-08-15 2012-01-31 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
US8122763B2 (en) * 2006-09-01 2012-02-28 Avair, Llc Breathing gas supply visual broadcast apparatus
US20080131522A1 (en) 2006-10-03 2008-06-05 Qing Liu Use of placental biomaterial for ocular surgery
WO2008060377A2 (en) 2006-10-04 2008-05-22 Anthrogenesis Corporation Placental or umbilical cord tissue compositions
CN104623642A (zh) 2006-10-06 2015-05-20 人类起源公司 天然(端肽)胎盘胶原组合物
EP2418271A3 (en) 2006-10-23 2015-09-30 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
CN101657206B (zh) 2007-02-12 2013-07-03 人类起源公司 利用胎盘干细胞治疗炎性疾病
JP2010518812A (ja) 2007-02-12 2010-06-03 アンスロジェネシス コーポレーション 接着性胎盤幹細胞由来の肝細胞および軟骨細胞、ならびにｃｄ３４＋、ｃｄ４５−胎盤幹細胞の濃縮細胞集団
CN101978045A (zh) 2007-09-26 2011-02-16 细胞基因细胞疗法公司 来自人胎盘灌洗液的血管生成细胞
CN101878034B (zh) 2007-09-28 2013-11-20 细胞基因细胞疗法公司 使用人胎盘灌洗液和人来自胎盘的中间体自然杀伤细胞的肿瘤抑制
EP3345609A1 (en) 2007-11-07 2018-07-11 Anthrogenesis Corporation Use of umbilical cord blood in the treatment of premature birth complications
KR20240052847A (ko) 2008-08-20 2024-04-23 셀룰래리티 인코포레이티드 개선된 세포 조성물 및 그의 제조 방법
JP5950577B2 (ja) 2008-08-20 2016-07-13 アンスロジェネシス コーポレーション 単離胎盤細胞を使用した脳卒中の治療
US8728805B2 (en) 2008-08-22 2014-05-20 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
NZ592726A (en) 2008-11-19 2012-12-21 Anthrogenesis Corp Amnion derived adherent cells
MX2011005230A (es) 2008-11-21 2011-06-16 Anthrogenesis Corp Tratamiento de enfermedades, desordenes o condiciones del pulmon usando celulas de placenta.

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001503384A (ja) * 1996-07-24 2001-03-13 セルジーン コーポレイション 置換２―（２，６―ジオキソピペリジン―３―イル）フタルイミド類及び―１―オキソイソインドリン類ならびにＴＮＦαレベルの減少方法
JP2002501536A (ja) * 1997-05-30 2002-01-15 セルジーン コーポレイション 置換２−（２，６−ジオキソピペリジン−３−イル）−フタルイミド類及び１−オキソイソインドリン類ならびにＴＮＦαレベルの減少方法
JP2004528021A (ja) * 2001-02-14 2004-09-16 アンスロジェネシス コーポレーション 分娩後の哺乳動物の胎盤、その使用およびそれに由来する胎盤幹細胞
WO2003087392A2 (en) * 2002-04-12 2003-10-23 Celgene Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
JP2005522215A (ja) * 2002-04-12 2005-07-28 セルジーン・コーポレーション 幹細胞及び前駆細胞の分化のモジュレーション、アッセイ、並びにそれらの使用
JP2005528105A (ja) * 2002-05-30 2005-09-22 セルジーン・コーポレーション 細胞分化をモジュレートするため、並びに骨髄増殖性疾患及び骨髄異形成症候群を治療するためのｊｎｋ又はｍｋｋ阻害剤の使用方法
WO2004035064A1 (en) * 2002-10-15 2004-04-29 Celgene Corporation Methods of using and compositions comprising immunomodulatory compounds for the treatment and management of myelodysplastic syndromes
WO2004043377A2 (en) * 2002-11-06 2004-05-27 Celgene Corporation Methods and compositions using immunomodulatory compounds for treatment and management of cancers and other diseases
WO2004043464A1 (en) * 2002-11-06 2004-05-27 Celgene Corporation Methods of using and compositions comprising immunomudulatory compounds for the treatment and management of myeloproliferative diseases
WO2005003334A2 (en) * 2003-06-27 2005-01-13 Ethicon, Incorporated Postpartum cells derived from umbilical cord tissue, and methods of making and using the same

Cited By (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9756851B2 (en) 1997-09-23 2017-09-12 The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US9756849B2 (en) 1997-09-23 2017-09-12 The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US9756850B2 (en) 1997-09-23 2017-09-12 The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US10321676B2 (en) 2004-10-07 2019-06-18 Transmedics, Inc. System and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US12396454B2 (en) 2004-10-07 2025-08-26 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US10736314B2 (en) 2004-10-07 2020-08-11 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US12137683B2 (en) 2004-10-07 2024-11-12 Transmedics, Inc. Systems and methods for ex-vivo organ care
US11191263B2 (en) 2004-10-07 2021-12-07 Transmedics, Inc. Systems and methods for ex-vivo organ care
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US10314303B2 (en) 2004-10-07 2019-06-11 Transmedics, Inc. Systems and methods for ex-vivo organ care
US11723357B2 (en) 2004-10-07 2023-08-15 Transmedics, Inc. Systems and methods for ex-vivo organ care
US11570985B2 (en) 2004-10-07 2023-02-07 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US9894894B2 (en) 2004-10-07 2018-02-20 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US10039276B2 (en) 2005-06-28 2018-08-07 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US11844345B2 (en) 2005-06-28 2023-12-19 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US11917991B2 (en) 2007-03-20 2024-03-05 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US10327443B2 (en) 2007-03-20 2019-06-25 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US12207649B2 (en) 2007-03-20 2025-01-28 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US9814230B2 (en) 2008-01-31 2017-11-14 Transmedics, Inc. Systems and methods for ex vivo lung care
US10750738B2 (en) 2008-01-31 2020-08-25 Transmedics, Inc. Systems and methods for ex vivo lung care
US12317888B2 (en) 2008-01-31 2025-06-03 Transmedics, Inc Systems and methods for ex vivo lung care
US9516875B2 (en) 2008-01-31 2016-12-13 Transmedics, Inc. Systems and methods for ex vivo lung care
JP2012029623A (ja) * 2010-07-30 2012-02-16 Bio Link Inc 細胞分離用酵素溶液及び細胞分離方法、並びに膵島分離方法
WO2012014911A1 (ja) * 2010-07-30 2012-02-02 株式会社 バイオリンクインク 細胞分離用酵素溶液及び細胞分離方法、並びに膵島分離方法
WO2012063870A1 (ja) * 2010-11-09 2012-05-18 株式会社大塚製薬工場 幹細胞懸濁液
JP2013223504A (ja) * 2010-11-09 2013-10-31 Otsuka Pharmaceut Factory Inc 細胞生存率低下抑制剤
US10087421B2 (en) 2010-11-09 2018-10-02 Otsuka Pharmaceutical Factory, Inc. Stem cell suspension
JP2012115253A (ja) * 2010-11-09 2012-06-21 Otsuka Pharmaceut Factory Inc 幹細胞懸濁液
CN114375945A (zh) * 2011-04-14 2022-04-22 特兰斯迈迪茨公司 用于供体肺的离体机器灌注的器官护理溶液
JP2014517821A (ja) * 2011-04-14 2014-07-24 トランスメディクス，インコーポレイテッド ドナー肺のＥｘ−ｖｉｖｏにおける機械的灌流のための臓器保護溶液
US11856944B2 (en) 2011-04-14 2024-01-02 Transmedics, Inc. Organ care solution for ex-vivo machine perfusion of donor lungs
JP2013233102A (ja) * 2012-05-08 2013-11-21 Otsuka Pharmaceut Factory Inc トレハロース含有肺塞栓形成予防用哺乳動物細胞懸濁液
JP2016520550A (ja) * 2013-04-05 2016-07-14 ジルバーバーグ，クラウディア マトリクスメタロプロテイナーゼおよびその使用
US11903381B2 (en) 2014-06-02 2024-02-20 Transmedics, Inc. Ex vivo organ care system
US11944088B2 (en) 2014-06-02 2024-04-02 Transmedics, Inc. Ex vivo organ care system
US11154050B2 (en) 2014-06-02 2021-10-26 Transmedics, Inc. Ex vivo organ care system
US10076112B2 (en) 2014-06-02 2018-09-18 Transmedic, Inc. Ex vivo organ care system
US10194655B2 (en) 2015-09-09 2019-02-05 Transmedics, Inc. Aortic cannula for ex vivo organ care system
US12185718B2 (en) 2015-09-09 2025-01-07 Transmedics, Inc. Aortic cannula for ex vivo organ care system
US11122795B2 (en) 2015-09-09 2021-09-21 Transmedics, Inc. Aortic cannula for ex vivo organ care system

Also Published As

Publication number Publication date
EP1974013A2 (en) 2008-10-01
US20100291679A1 (en) 2010-11-18
US9598669B2 (en) 2017-03-21
US20190376027A1 (en) 2019-12-12
WO2007079185A3 (en) 2007-12-13
CA2633980A1 (en) 2007-07-12
IL191771A0 (en) 2008-12-29
US10590381B2 (en) 2020-03-17
KR20080097190A (ko) 2008-11-04
US9725694B2 (en) 2017-08-08
ZA200804717B (en) 2010-02-24
US20070190042A1 (en) 2007-08-16
CN101374941A (zh) 2009-02-25
AU2006332680A1 (en) 2007-07-12
US20170327788A1 (en) 2017-11-16
WO2007079185A2 (en) 2007-07-12
IL191771A (en) 2012-06-28
PE20071015A1 (es) 2007-10-24

Similar Documents

Publication Publication Date Title
US10590381B2 (en) Composition for collecting and preserving placental stem cells and methods of using the composition
JP2005528105A (ja) 細胞分化をモジュレートするため、並びに骨髄増殖性疾患及び骨髄異形成症候群を治療するためのｊｎｋ又はｍｋｋ阻害剤の使用方法
JP2022166249A (ja) ヒト胎盤灌流液由来の血管形成細胞
DK2084268T3 (en) METHODS AND COMPOSITIONS FOR TREATING BONE JOIN DEFECTS WITH PLACENTACLE POPULATIONS
JP2020097604A (ja) 単離胎盤細胞を使用した脳卒中の治療
JP2020105207A (ja) 改良型細胞組成物およびその作製方法
KR20130092394A (ko) 태반 줄기 세포를 사용한 사르코이드증의 치료
CN105026553A (zh) 用于获得富集的间充质干细胞培养物的组合物和方法
JP2023103416A (ja) 拡張型心筋症治療剤
WO2019131942A1 (ja) 細胞凝集促進剤
HK1127511A (en) Improved composition for collecting and preserving placental stem cells and methods of using the composition
CN111788300B (zh) 细胞聚集抑制剂
JPWO2017010448A1 (ja) ネフロン形成能を有するネフロン前駆細胞の増幅培養方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20091225

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20091225

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20120417

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20121009