JP2009521931A5 - - Google Patents
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- JP2009521931A5 JP2009521931A5 JP2008548747A JP2008548747A JP2009521931A5 JP 2009521931 A5 JP2009521931 A5 JP 2009521931A5 JP 2008548747 A JP2008548747 A JP 2008548747A JP 2008548747 A JP2008548747 A JP 2008548747A JP 2009521931 A5 JP2009521931 A5 JP 2009521931A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- aryl
- compound
- heterocycle
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 125000000217 alkyl group Chemical group 0.000 claims 21
- 150000001875 compounds Chemical class 0.000 claims 19
- 125000003118 aryl group Chemical group 0.000 claims 16
- 125000000623 heterocyclic group Chemical group 0.000 claims 15
- 238000000034 method Methods 0.000 claims 15
- 229910052739 hydrogen Inorganic materials 0.000 claims 14
- 239000001257 hydrogen Substances 0.000 claims 13
- 125000001424 substituent group Chemical group 0.000 claims 12
- 125000000592 heterocycloalkyl group Chemical group 0.000 claims 10
- 125000003710 aryl alkyl group Chemical group 0.000 claims 9
- 125000001072 heteroaryl group Chemical group 0.000 claims 7
- 150000002431 hydrogen Chemical class 0.000 claims 7
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 claims 6
- 125000004648 C2-C8 alkenyl group Chemical group 0.000 claims 6
- 125000004649 C2-C8 alkynyl group Chemical group 0.000 claims 6
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 6
- 229940118135 JNK inhibitor Drugs 0.000 claims 6
- 239000012825 JNK inhibitor Substances 0.000 claims 6
- 125000003545 alkoxy group Chemical group 0.000 claims 6
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 6
- 125000004432 carbon atom Chemical group C* 0.000 claims 6
- 230000002519 immonomodulatory effect Effects 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- 239000012453 solvate Substances 0.000 claims 6
- 229910052736 halogen Inorganic materials 0.000 claims 5
- 150000002367 halogens Chemical class 0.000 claims 5
- 210000000130 stem cell Anatomy 0.000 claims 5
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 4
- -1 hydroxy, carboxy Chemical group 0.000 claims 4
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 4
- 125000004183 alkoxy alkyl group Chemical group 0.000 claims 3
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 claims 2
- 229940088872 Apoptosis inhibitor Drugs 0.000 claims 2
- 108010055717 JNK Mitogen-Activated Protein Kinases Proteins 0.000 claims 2
- 125000004423 acyloxy group Chemical group 0.000 claims 2
- 125000004103 aminoalkyl group Chemical group 0.000 claims 2
- 239000000158 apoptosis inhibitor Substances 0.000 claims 2
- 125000004429 atom Chemical group 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 125000004093 cyano group Chemical group *C#N 0.000 claims 2
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- 125000001188 haloalkyl group Chemical group 0.000 claims 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 claims 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 2
- 125000004963 sulfonylalkyl group Chemical group 0.000 claims 2
- 125000004001 thioalkyl group Chemical group 0.000 claims 2
- 125000001989 1,3-phenylene group Chemical group [H]C1=C([H])C([*:1])=C([H])C([*:2])=C1[H] 0.000 claims 1
- 125000001140 1,4-phenylene group Chemical group [H]C1=C([H])C([*:2])=C([H])C([H])=C1[*:1] 0.000 claims 1
- GQBONCZDJQXPLV-UHFFFAOYSA-N 4-aminoisoindole-1,3-dione Chemical compound NC1=CC=CC2=C1C(=O)NC2=O GQBONCZDJQXPLV-UHFFFAOYSA-N 0.000 claims 1
- 125000005083 alkoxyalkoxy group Chemical group 0.000 claims 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 1
- 125000005078 alkoxycarbonylalkyl group Chemical group 0.000 claims 1
- 125000001118 alkylidene group Chemical group 0.000 claims 1
- 125000002431 aminoalkoxy group Chemical group 0.000 claims 1
- 125000001691 aryl alkyl amino group Chemical group 0.000 claims 1
- 125000002102 aryl alkyloxo group Chemical group 0.000 claims 1
- 125000001769 aryl amino group Chemical group 0.000 claims 1
- 125000005160 aryl oxy alkyl group Chemical group 0.000 claims 1
- 125000004104 aryloxy group Chemical group 0.000 claims 1
- 125000005605 benzo group Chemical group 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 125000001309 chloro group Chemical group Cl* 0.000 claims 1
- 125000000000 cycloalkoxy group Chemical group 0.000 claims 1
- 125000006310 cycloalkyl amino group Chemical group 0.000 claims 1
- 125000005112 cycloalkylalkoxy group Chemical group 0.000 claims 1
- 230000004069 differentiation Effects 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 125000003453 indazolyl group Chemical group N1N=C(C2=C1C=CC=C2)* 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- GOTYRUGSSMKFNF-UHFFFAOYSA-N lenalidomide Chemical compound C1C=2C(N)=CC=CC=2C(=O)N1C1CCC(=O)NC1=O GOTYRUGSSMKFNF-UHFFFAOYSA-N 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
- KNCYXPMJDCCGSJ-UHFFFAOYSA-N piperidine-2,6-dione Chemical compound O=C1CCCC(=O)N1 KNCYXPMJDCCGSJ-UHFFFAOYSA-N 0.000 claims 1
- UVSMNLNDYGZFPF-UHFFFAOYSA-N pomalidomide Chemical compound O=C1C=2C(N)=CC=CC=2C(=O)N1C1CCC(=O)NC1=O UVSMNLNDYGZFPF-UHFFFAOYSA-N 0.000 claims 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75496905P | 2005-12-29 | 2005-12-29 | |
| PCT/US2006/049493 WO2007079185A2 (en) | 2005-12-29 | 2006-12-28 | Improved composition for collecting and preserving placental stem cells and methods of using the composition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009521931A JP2009521931A (ja) | 2009-06-11 |
| JP2009521931A5 true JP2009521931A5 (cg-RX-API-DMAC7.html) | 2010-02-18 |
Family
ID=38228854
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008548747A Pending JP2009521931A (ja) | 2005-12-29 | 2006-12-28 | 胎盤幹細胞を収集及び保存するための改善された組成物、及び該組成物の使用方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US9598669B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1974013A2 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2009521931A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20080097190A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101374941A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2006332680A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2633980A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL191771A (cg-RX-API-DMAC7.html) |
| PE (1) | PE20071015A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007079185A2 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200804717B (cg-RX-API-DMAC7.html) |
Families Citing this family (110)
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| US8409846B2 (en) | 1997-09-23 | 2013-04-02 | The United States Of America As Represented By The Department Of Veteran Affairs | Compositions, methods and devices for maintaining an organ |
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| ES2548591T3 (es) | 2001-02-14 | 2015-10-19 | Anthrogenesis Corporation | Placenta post-parto de mamífero, su uso y células madre placentarias de la misma |
| EP2336299A1 (en) | 2001-02-14 | 2011-06-22 | Anthrogenesis Corporation | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| US7498171B2 (en) * | 2002-04-12 | 2009-03-03 | Anthrogenesis Corporation | Modulation of stem and progenitor cell differentiation, assays, and uses thereof |
| BR0316695A (pt) * | 2002-11-26 | 2005-10-18 | Anthrogenesis Corp | Unidade citoterapêutica, kit para tratamento, método de tratamento de uma enfermidade, biblioteca de unidades citoterapêuticas e método de tratamento de um paciente |
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2006
- 2006-12-28 JP JP2008548747A patent/JP2009521931A/ja active Pending
- 2006-12-28 AU AU2006332680A patent/AU2006332680A1/en not_active Abandoned
- 2006-12-28 US US11/648,812 patent/US9598669B2/en not_active Expired - Fee Related
- 2006-12-28 CN CNA2006800529409A patent/CN101374941A/zh active Pending
- 2006-12-28 EP EP06848282A patent/EP1974013A2/en not_active Withdrawn
- 2006-12-28 WO PCT/US2006/049493 patent/WO2007079185A2/en not_active Ceased
- 2006-12-28 KR KR1020087018724A patent/KR20080097190A/ko not_active Withdrawn
- 2006-12-28 CA CA002633980A patent/CA2633980A1/en not_active Abandoned
- 2006-12-28 ZA ZA200804717A patent/ZA200804717B/xx unknown
- 2006-12-29 PE PE2006001721A patent/PE20071015A1/es not_active Application Discontinuation
-
2008
- 2008-05-27 IL IL191771A patent/IL191771A/en active IP Right Grant
-
2010
- 2010-07-29 US US12/846,765 patent/US9725694B2/en active Active
-
2017
- 2017-07-28 US US15/663,475 patent/US10590381B2/en active Active
-
2019
- 2019-08-22 US US16/548,720 patent/US20190376027A1/en not_active Abandoned
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