JP2008528445A5 - - Google Patents

Download PDF

Info

Publication number
JP2008528445A5
JP2008528445A5 JP2007547612A JP2007547612A JP2008528445A5 JP 2008528445 A5 JP2008528445 A5 JP 2008528445A5 JP 2007547612 A JP2007547612 A JP 2007547612A JP 2007547612 A JP2007547612 A JP 2007547612A JP 2008528445 A5 JP2008528445 A5 JP 2008528445A5
Authority
JP
Japan
Prior art keywords
formula
vector
compound
peptide
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2007547612A
Other languages
English (en)
Japanese (ja)
Other versions
JP5743372B2 (ja
JP2008528445A (ja
Filing date
Publication date
Priority claimed from GBGB0428012.9A external-priority patent/GB0428012D0/en
Application filed filed Critical
Publication of JP2008528445A publication Critical patent/JP2008528445A/ja
Publication of JP2008528445A5 publication Critical patent/JP2008528445A5/ja
Application granted granted Critical
Publication of JP5743372B2 publication Critical patent/JP5743372B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2007547612A 2004-12-22 2005-12-09 放射性標識法 Expired - Lifetime JP5743372B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0428012.9A GB0428012D0 (en) 2004-12-22 2004-12-22 Radiolabelling methods
GB0428012.9 2004-12-22
PCT/GB2005/004729 WO2006067376A2 (en) 2004-12-22 2005-12-09 Radiolabelled conjugates of rgd-containing peptides and methods for their preparation via click-chemistry

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012167865A Division JP2012254998A (ja) 2004-12-22 2012-07-30 放射性標識法

Publications (3)

Publication Number Publication Date
JP2008528445A JP2008528445A (ja) 2008-07-31
JP2008528445A5 true JP2008528445A5 (enExample) 2012-09-13
JP5743372B2 JP5743372B2 (ja) 2015-07-01

Family

ID=34112991

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2007547612A Expired - Lifetime JP5743372B2 (ja) 2004-12-22 2005-12-09 放射性標識法
JP2012167865A Pending JP2012254998A (ja) 2004-12-22 2012-07-30 放射性標識法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2012167865A Pending JP2012254998A (ja) 2004-12-22 2012-07-30 放射性標識法

Country Status (13)

Country Link
US (2) US7972588B2 (enExample)
EP (4) EP2275145A1 (enExample)
JP (2) JP5743372B2 (enExample)
KR (1) KR101314460B1 (enExample)
CN (2) CN105012972A (enExample)
AU (1) AU2005317903C1 (enExample)
BR (1) BRPI0519317A2 (enExample)
CA (2) CA2589136C (enExample)
GB (1) GB0428012D0 (enExample)
MX (1) MX2007007560A (enExample)
NO (1) NO341638B1 (enExample)
RU (1) RU2419627C2 (enExample)
WO (1) WO2006067376A2 (enExample)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0428012D0 (en) * 2004-12-22 2005-01-26 Hammersmith Imanet Ltd Radiolabelling methods
US8071718B2 (en) 2004-12-22 2011-12-06 General Electric Company Selective radiolabeling of biomolecules
WO2007148074A1 (en) * 2006-06-21 2007-12-27 Hammersmith Imanet Limited Chemical methods and apparatus
JP2009541288A (ja) 2006-06-21 2009-11-26 ハマースミス・イメイネット・リミテッド 放射性標識方法
CN101528270A (zh) * 2006-08-28 2009-09-09 通用电气健康护理有限公司 基于68Ga标记的肽的放射性药物
WO2008025886A1 (en) * 2006-09-01 2008-03-06 Wallac Oy Metal chelates and chelating agents containing triazolyl subunits
US8652440B2 (en) * 2007-05-10 2014-02-18 The Trustees Of Columbia University In The City Of New York Methods for diagnosing diseases and evaluating treatments therefor using PET
WO2009080561A1 (en) * 2007-12-20 2009-07-02 General Electric Company Selective radiolabeling of biomolecules
EP2147684A1 (en) * 2008-07-22 2010-01-27 Bracco Imaging S.p.A Diagnostic Agents Selective Against Metalloproteases
GB0815831D0 (en) * 2008-09-01 2008-10-08 Imp Innovations Ltd Compounds
EP2367816B1 (en) 2008-09-05 2016-11-09 Imperial Innovations Limited Isatin derivatives for use as in vivo imaging agents
CA2736861C (en) * 2008-10-10 2017-11-14 Roger Schibli 18f-labelled folates as pet radiotracers
US20120165650A1 (en) 2010-12-22 2012-06-28 General Electric Company Her2 binders
EP2210882A1 (en) * 2009-01-16 2010-07-28 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Synthesis of new protected azahistidine, their processes and their use in synthesises
US8435488B2 (en) * 2009-02-27 2013-05-07 Genentech, Inc. Methods and compositions for protein labelling
US8722014B2 (en) * 2009-05-01 2014-05-13 Washington University 1 H-[1, 2, 3] triazole substituted amino acids and uses thereof
GB0914543D0 (en) * 2009-08-20 2009-09-30 Ge Healthcare Ltd Radioiodination method
WO2011058002A1 (en) * 2009-11-11 2011-05-19 Neurosearch A/S Labelled pyrrolyl-oxadiazolyl-diazabicyclononane derivatives and their use in diagnostic methods
GB0921573D0 (en) 2009-12-10 2010-01-27 Ge Healthcare Ltd Iodine radiolabelling method
GB0922304D0 (en) 2009-12-22 2010-02-03 Ge Healthcare Ltd Radioiodinated compounds
WO2011079245A1 (en) * 2009-12-23 2011-06-30 Board Of Regents Of The University Of Nebraska Targeted radiolabeled compounds and their use for the treatment and diagnosis of cancer
WO2011130530A1 (en) * 2010-04-14 2011-10-20 The Mclean Hospital Corporation 2-alkoxy-11-hydroxyaporphine derivatives and uses thereof
EP2575897A4 (en) * 2010-06-01 2016-06-01 Advanced Proteome Therapeutics Inc CROSSLINKING OF PROTEINS AND OTHER ENTITIES THROUGH ALPHA-HALO-ACETOPHENONES CONJUGATES, BENZYL HALIDES, QUINONES
CN103221398B (zh) * 2010-07-23 2016-03-23 特拉华大学 用于快速构建放射性核素标记探针的四嗪-反式环辛烯连接反应
GB201014023D0 (en) * 2010-08-20 2010-10-06 Ucl Business Plc Process for producing bioconjugates and products thereof
WO2012074840A2 (en) 2010-11-22 2012-06-07 The General Hospital Corporation Compositions and methods for in vivo imaging
GB201019824D0 (en) 2010-11-23 2011-01-05 Ge Healthcare Ltd Radioiodination method
GB201021369D0 (en) 2010-12-16 2011-01-26 Ge Healthcare Ltd Radioiodinated fatty acids
GB201021517D0 (en) 2010-12-20 2011-02-02 Ge Healthcare Ltd Radioiodinated guanidines
NZ612327A (en) 2010-12-22 2015-03-27 Ge Healthcare Ltd Her2 binding peptides labelled with a 18f - containing organosilicon compound
EP2654803B1 (en) 2010-12-22 2021-08-18 General Electric Company Radiolabeled her2-binding peptide conjugates
MX2013010012A (es) * 2011-03-01 2014-04-14 Ge Healthcare Ltd Analogos de octreotato radiomarcado como trazadores de tomografia por emision de positrones.
US20120251448A1 (en) * 2011-03-03 2012-10-04 Hefti Franz F Compounds for Use in the Detection of Neurodegenerative Diseases
US9023318B2 (en) * 2011-06-08 2015-05-05 Siemens Medical Solutions Usa, Inc. Compounds with matrix-metalloproteinase inhibitory activity and imaging agents thereof
WO2013048832A1 (en) 2011-09-29 2013-04-04 Ge Healthcare Limited 18 f - labelled 6 - ( 2 - fluoroethoxy) - 2 - naphthaldehyde for detecting cancer stem cells
WO2013048811A1 (en) 2011-09-30 2013-04-04 Ge Healthcare Limited Imaging and radiotherapy methods for tumour stem cells
US20140335019A1 (en) * 2011-12-02 2014-11-13 The Regents Of The University Of Michigan Compositions and methods for the treatment and analysis of neurological disorders
GB201121911D0 (en) 2011-12-20 2012-02-01 Ge Healthcare Ltd Radiofluorination method
WO2013113680A1 (en) * 2012-02-03 2013-08-08 Aarhus Universitet Radiolabeled bile acids and bile acid derivatives
EP2657213A1 (en) * 2012-04-24 2013-10-30 Institut National de la Santé et de la Recherche Medicale Labelled quinoxaline derivatives as multimodal radiopharmaceuticals and their precursors
US20140065070A1 (en) * 2012-08-28 2014-03-06 Mcmaster University Methods of preparing triazole-containing radioiodinated compounds
US20160137639A1 (en) * 2012-10-26 2016-05-19 Japan Tobacco Inc. Triazole-isoxazole compound and medical use thereof
US20150023877A1 (en) * 2013-07-18 2015-01-22 The Board Of Trustees Of The Leland Stanford Junior University Methods of parkinsons disease diagnosis and monitoring treatment
EP3424909A1 (en) * 2014-01-05 2019-01-09 Washington University A poly (adp-ribose) polymerase-1 (parp-1) inhibitor and uses therefor
US20160022846A1 (en) * 2014-07-22 2016-01-28 Ge Healthcare Limited Iodine radiolabelling method
EP3795591B1 (en) * 2015-06-19 2023-09-27 Eisai R&D Management Co., Ltd. Cys80 conjugated immunoglobulins
WO2017023999A1 (en) * 2015-08-03 2017-02-09 Emory University Methylsulfonamide derivatives and uses related thereto
WO2019227490A1 (en) 2018-06-01 2019-12-05 Tayu Huaxia Biotech Medical Group Co., Ltd. Compositions and methods for imaging
CN112638415B (zh) * 2018-07-26 2024-07-02 大有华夏生物医药集团有限公司 用于成像的组合物和方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4913891A (en) * 1986-04-17 1990-04-03 The United States Of America As Represented By The United States Department Of Energy Positron emitter labeled enzyme inhibitors
EP1292577B1 (en) * 2000-03-24 2012-10-24 Euro-Celtique S.A. Aryl substituted pyrazoles, triazoles and tetrazoles as sodium channel blocker
US6350360B1 (en) 2000-04-07 2002-02-26 Sandia Coroporation Method of fabricating a 3-dimensional tool master
JP5043271B2 (ja) * 2000-04-12 2012-10-10 ジーイー・ヘルスケア・アクスイェ・セルスカプ ペプチドベースの化合物
GB0115927D0 (en) 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination
CN1622830A (zh) 2001-07-10 2005-06-01 安盛药业有限公司 肽基化合物
US7375234B2 (en) 2002-05-30 2008-05-20 The Scripps Research Institute Copper-catalysed ligation of azides and acetylenes
WO2004055160A2 (en) * 2002-12-13 2004-07-01 The Trustees Of Columbia University In The City Of New York Biomolecular coupling methods using 1,3-dipolar cycloaddition chemistry
JP5642916B2 (ja) * 2003-04-17 2014-12-17 ザ スクリプス リサーチ インスティテュート 真核遺伝コードの拡張
JP5275566B2 (ja) * 2003-06-18 2013-08-28 ザ スクリプス リサーチ インスティチュート 反応性非天然アミノ酸遺伝コード付加
NO20033115D0 (no) 2003-07-08 2003-07-08 Amersham Health As Peptid-baserte forbindelser
WO2006038184A2 (en) * 2004-10-07 2006-04-13 Koninklijke Philips Electronics N.V. Compounds, kits and methods for use in medical imaging
GB0428012D0 (en) * 2004-12-22 2005-01-26 Hammersmith Imanet Ltd Radiolabelling methods

Similar Documents

Publication Publication Date Title
JP2009541288A5 (enExample)
JP2006502283A5 (enExample)
JP2016153410A5 (enExample)
JP2007530441A5 (enExample)
JP2011503184A5 (enExample)
JP2010525122A5 (enExample)
JP2016523313A5 (enExample)
US11976094B2 (en) Method for preparing peptides
JP7063409B1 (ja) Fmоc基を除去する方法
ES2662644T3 (es) Reactivos de metileno
ATE355259T1 (de) Radiofluorierungsverfahren
JP2018502174A5 (enExample)
JP7154513B1 (ja) 液相ペプチド製造方法
TW200831527A (en) Method of peptide synthesis
AR091075A1 (es) Proceso para preparar derivados monociclicos de heteroaril-cicloalquil-diamina
JP7249591B2 (ja) 分解性ポリエチレングリコール結合体
RU2014102887A (ru) Прямой синтез 18f-фторметокси соединений для пэт визуализации и новые предшественники для прямого радиосинтеза защищенных производных o-([18f]фторметил)тирозина
JP2015532915A (ja) ボルテゾミブの製造方法
JP2009522364A5 (enExample)
ES2578798T3 (es) Método de ligación nativa
RU2016134328A (ru) Конъюгаты фактора свёртывания крови vii
WO2025125621A1 (en) Cancer-associated protein-targeted strong or covalently binding precursor compounds and radiotracers
JP2013509396A5 (enExample)
CN105936626B (zh) 一种氨基保护基的制备方法
KR101142153B1 (ko) 개선된 플루오르-18 표지를 위한 트리아자노난 유도체 또는 이의 약학적으로 허용가능한 염