GB0428012D0 - Radiolabelling methods - Google Patents

Radiolabelling methods

Info

Publication number
GB0428012D0
GB0428012D0 GBGB0428012.9A GB0428012A GB0428012D0 GB 0428012 D0 GB0428012 D0 GB 0428012D0 GB 0428012 A GB0428012 A GB 0428012A GB 0428012 D0 GB0428012 D0 GB 0428012D0
Authority
GB
United Kingdom
Prior art keywords
radiolabelling methods
radiolabelling
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0428012.9A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hammersmith Imanet Ltd
Original Assignee
Hammersmith Imanet Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hammersmith Imanet Ltd filed Critical Hammersmith Imanet Ltd
Priority to GBGB0428012.9A priority Critical patent/GB0428012D0/en
Publication of GB0428012D0 publication Critical patent/GB0428012D0/en
Priority to US11/721,694 priority patent/US7972588B2/en
Priority to CA2589136A priority patent/CA2589136C/en
Priority to MX2007007560A priority patent/MX2007007560A/es
Priority to AU2005317903A priority patent/AU2005317903C1/en
Priority to BRPI0519317-6A priority patent/BRPI0519317A2/pt
Priority to JP2007547612A priority patent/JP5743372B2/ja
Priority to EP20100179459 priority patent/EP2258403A1/en
Priority to CNA2005800441130A priority patent/CN101084020A/zh
Priority to EP10179446.9A priority patent/EP2266629B1/en
Priority to RU2007122804/04A priority patent/RU2419627C2/ru
Priority to CA2817636A priority patent/CA2817636A1/en
Priority to KR1020077014048A priority patent/KR101314460B1/ko
Priority to CN201510494983.3A priority patent/CN105012972A/zh
Priority to PCT/GB2005/004729 priority patent/WO2006067376A2/en
Priority to EP05818037A priority patent/EP1830890A2/en
Priority to EP20100179449 priority patent/EP2275145A1/en
Priority to NO20073157A priority patent/NO341638B1/no
Priority to US11/961,108 priority patent/US8071718B2/en
Priority to US13/158,555 priority patent/US8679455B2/en
Priority to JP2012167865A priority patent/JP2012254998A/ja
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1051—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from breast, e.g. the antibody being herceptin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
GBGB0428012.9A 2004-12-22 2004-12-22 Radiolabelling methods Ceased GB0428012D0 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
GBGB0428012.9A GB0428012D0 (en) 2004-12-22 2004-12-22 Radiolabelling methods
EP20100179449 EP2275145A1 (en) 2004-12-22 2005-12-09 Reagents and methods for radiolabelling of RGD-containing peptides
RU2007122804/04A RU2419627C2 (ru) 2004-12-22 2005-12-09 Меченные радиоактивным изотопом конъюгаты rgd-содержащих пептидов и способы их получения с помощью click-химии
KR1020077014048A KR101314460B1 (ko) 2004-12-22 2005-12-09 Ｒｇｄ-함유 펩티드의 방사성 표지된 접합체 및클릭-화학을 통한 그의 제조 방법
MX2007007560A MX2007007560A (es) 2004-12-22 2005-12-09 Metodos de radioetiquetacion.
AU2005317903A AU2005317903C1 (en) 2004-12-22 2005-12-09 Radiolabelled conjugates of RGD-containing peptides and methods for their preparation via click-chemistry
BRPI0519317-6A BRPI0519317A2 (pt) 2004-12-22 2005-12-09 mÉtodo para marcar um vetor, composto, composiÇço radiofarmacÊutica, uso de um composto, e, mÉtodos para gerar uma imagem de um corpo humano ou animal e para monitorar o efeito do tratamento de um corpo humano ou animal com uma droga para combater uma condiÇço associada com cÂncer
JP2007547612A JP5743372B2 (ja) 2004-12-22 2005-12-09 放射性標識法
EP20100179459 EP2258403A1 (en) 2004-12-22 2005-12-09 Radiolabelled conjugates of RGD-containing peptides and methods for their preparation via click-chemistry
CNA2005800441130A CN101084020A (zh) 2004-12-22 2005-12-09 放射性标记方法
EP10179446.9A EP2266629B1 (en) 2004-12-22 2005-12-09 Reagents and methods for radiolabelling of RGD-containing peptides.
US11/721,694 US7972588B2 (en) 2004-12-22 2005-12-09 Radiolabelling methods
CA2817636A CA2817636A1 (en) 2004-12-22 2005-12-09 Radiolabelled conjugates of rgd-containing peptides and methods for their preparation via click-chemistry
CA2589136A CA2589136C (en) 2004-12-22 2005-12-09 Radiolabelled conjugates of rgd-containing peptides and methods for their preparation via click-chemistry
CN201510494983.3A CN105012972A (zh) 2004-12-22 2005-12-09 放射性标记方法
PCT/GB2005/004729 WO2006067376A2 (en) 2004-12-22 2005-12-09 Radiolabelled conjugates of rgd-containing peptides and methods for their preparation via click-chemistry
EP05818037A EP1830890A2 (en) 2004-12-22 2005-12-09 Radiolabelled conjugates of rgd-containing peptides and methods for their preparation via click-chemistry
NO20073157A NO341638B1 (no) 2004-12-22 2007-06-20 Framgangsmåte for å merke en vektor, nye forbindelser og bruk av disse i fremstilling av et radiofarmasøytikum, samt en radiofarmasøytisk sammensetning
US11/961,108 US8071718B2 (en) 2004-12-22 2007-12-20 Selective radiolabeling of biomolecules
US13/158,555 US8679455B2 (en) 2004-12-22 2011-06-13 Radiolabelling methods
JP2012167865A JP2012254998A (ja) 2004-12-22 2012-07-30 放射性標識法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0428012.9A GB0428012D0 (en) 2004-12-22 2004-12-22 Radiolabelling methods

Publications (1)

Publication Number Publication Date
GB0428012D0 true GB0428012D0 (en) 2005-01-26

Family

ID=34112991

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0428012.9A Ceased GB0428012D0 (en) 2004-12-22 2004-12-22 Radiolabelling methods

Country Status (13)

Country Link
US (2) US7972588B2 (enExample)
EP (4) EP2275145A1 (enExample)
JP (2) JP5743372B2 (enExample)
KR (1) KR101314460B1 (enExample)
CN (2) CN101084020A (enExample)
AU (1) AU2005317903C1 (enExample)
BR (1) BRPI0519317A2 (enExample)
CA (2) CA2817636A1 (enExample)
GB (1) GB0428012D0 (enExample)
MX (1) MX2007007560A (enExample)
NO (1) NO341638B1 (enExample)
RU (1) RU2419627C2 (enExample)
WO (1) WO2006067376A2 (enExample)

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GB0428012D0 (en) * 2004-12-22 2005-01-26 Hammersmith Imanet Ltd Radiolabelling methods
US8071718B2 (en) 2004-12-22 2011-12-06 General Electric Company Selective radiolabeling of biomolecules
US8211403B2 (en) 2006-06-21 2012-07-03 Hammersmith Imanet Limited Radiolabelling methods
US20100069609A1 (en) * 2006-06-21 2010-03-18 Erik Arstad Chemical methods and apparatus
CN101528270A (zh) * 2006-08-28 2009-09-09 通用电气健康护理有限公司 基于68Ga标记的肽的放射性药物
WO2008025886A1 (en) * 2006-09-01 2008-03-06 Wallac Oy Metal chelates and chelating agents containing triazolyl subunits
EP2155259A2 (en) * 2007-05-10 2010-02-24 The Trustees of Columbia University in the City of New York Methods for diagnosing diseases and evaluating treatments therefor using pet
ES2662495T3 (es) 2007-12-20 2018-04-06 General Electric Company Radiomarcación selectiva de biomoléculas
EP2147684A1 (en) * 2008-07-22 2010-01-27 Bracco Imaging S.p.A Diagnostic Agents Selective Against Metalloproteases
GB0815831D0 (en) * 2008-09-01 2008-10-08 Imp Innovations Ltd Compounds
CA2735970A1 (en) 2008-09-05 2010-03-11 Hammersmith Imanet Limited Isatin derivatives for use as in vivo imaging agents
CN102177160B (zh) * 2008-10-10 2014-11-26 默克及其合伙人公司 作为pet放射性示踪剂的18f-标记叶酸
US20120165650A1 (en) 2010-12-22 2012-06-28 General Electric Company Her2 binders
EP2210882A1 (en) * 2009-01-16 2010-07-28 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Synthesis of new protected azahistidine, their processes and their use in synthesises
US8435488B2 (en) * 2009-02-27 2013-05-07 Genentech, Inc. Methods and compositions for protein labelling
US8722014B2 (en) * 2009-05-01 2014-05-13 Washington University 1 H-[1, 2, 3] triazole substituted amino acids and uses thereof
GB0914543D0 (en) * 2009-08-20 2009-09-30 Ge Healthcare Ltd Radioiodination method
EP2498826A1 (en) * 2009-11-11 2012-09-19 NeuroSearch AS Labelled pyrrolyl-oxadiazolyl-diazabicyclononane derivatives and their use in diagnostic methods
GB0921573D0 (en) * 2009-12-10 2010-01-27 Ge Healthcare Ltd Iodine radiolabelling method
GB0922304D0 (en) 2009-12-22 2010-02-03 Ge Healthcare Ltd Radioiodinated compounds
US20120269725A1 (en) * 2009-12-23 2012-10-25 Janine Baranowska-Kortylewicz Targeted radiolabeled compounds and their use for the treatment and diagnosis of cancer
US9517279B2 (en) * 2010-04-14 2016-12-13 The Mclean Hospital Corporation 2-alkoxy-11-hydroxyaporphine derivatives and uses thereof
EP2575897A4 (en) * 2010-06-01 2016-06-01 Advanced Proteome Therapeutics Inc CROSSLINKING OF PROTEINS AND OTHER ENTITIES THROUGH ALPHA-HALO-ACETOPHENONES CONJUGATES, BENZYL HALIDES, QUINONES
CN103221398B (zh) * 2010-07-23 2016-03-23 特拉华大学 用于快速构建放射性核素标记探针的四嗪-反式环辛烯连接反应
GB201014023D0 (en) * 2010-08-20 2010-10-06 Ucl Business Plc Process for producing bioconjugates and products thereof
WO2012074840A2 (en) 2010-11-22 2012-06-07 The General Hospital Corporation Compositions and methods for in vivo imaging
GB201019824D0 (en) 2010-11-23 2011-01-05 Ge Healthcare Ltd Radioiodination method
GB201021369D0 (en) 2010-12-16 2011-01-26 Ge Healthcare Ltd Radioiodinated fatty acids
GB201021517D0 (en) 2010-12-20 2011-02-02 Ge Healthcare Ltd Radioiodinated guanidines
WO2012087912A1 (en) 2010-12-22 2012-06-28 Ge Healthcare Limited Her2 binding peptides labelled with a 18f - containing organosilicon compound
MX2013007365A (es) 2010-12-22 2013-09-26 Ge Healthcare Ltd Péptidos de enlace her2 etiquetados con fluoruro de aluminio- [18] combinados mediante nota.
EP2680889B1 (en) 2011-03-01 2019-06-19 GE Healthcare Limited Radiolabelled octreotate analogues as pet tracers
US20120251448A1 (en) * 2011-03-03 2012-10-04 Hefti Franz F Compounds for Use in the Detection of Neurodegenerative Diseases
US9023318B2 (en) * 2011-06-08 2015-05-05 Siemens Medical Solutions Usa, Inc. Compounds with matrix-metalloproteinase inhibitory activity and imaging agents thereof
WO2013048832A1 (en) 2011-09-29 2013-04-04 Ge Healthcare Limited 18 f - labelled 6 - ( 2 - fluoroethoxy) - 2 - naphthaldehyde for detecting cancer stem cells
WO2013048811A1 (en) 2011-09-30 2013-04-04 Ge Healthcare Limited Imaging and radiotherapy methods for tumour stem cells
US20140335019A1 (en) * 2011-12-02 2014-11-13 The Regents Of The University Of Michigan Compositions and methods for the treatment and analysis of neurological disorders
GB201121911D0 (en) 2011-12-20 2012-02-01 Ge Healthcare Ltd Radiofluorination method
US20150017093A1 (en) * 2012-02-03 2015-01-15 Aarhus Universitet Radiolabeled bile acids and bile acid derivatives
EP2657213A1 (en) * 2012-04-24 2013-10-30 Institut National de la Santé et de la Recherche Medicale Labelled quinoxaline derivatives as multimodal radiopharmaceuticals and their precursors
US20140065070A1 (en) * 2012-08-28 2014-03-06 Mcmaster University Methods of preparing triazole-containing radioiodinated compounds
US20160137639A1 (en) * 2012-10-26 2016-05-19 Japan Tobacco Inc. Triazole-isoxazole compound and medical use thereof
US20150023877A1 (en) * 2013-07-18 2015-01-22 The Board Of Trustees Of The Leland Stanford Junior University Methods of parkinsons disease diagnosis and monitoring treatment
ES2700348T3 (es) * 2014-01-05 2019-02-15 Univ Washington Trazadores radioetiquetados para poli (ADP-ribosa) polimerasa-1 (PARP-1), métodos y usos para estos
US20160022846A1 (en) * 2014-07-22 2016-01-28 Ge Healthcare Limited Iodine radiolabelling method
PT3310816T (pt) * 2015-06-19 2020-10-19 Eisai R&D Man Co Ltd Imunoglobulinas conjugadas cys80
WO2017023999A1 (en) * 2015-08-03 2017-02-09 Emory University Methylsulfonamide derivatives and uses related thereto
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Also Published As

Publication number Publication date
MX2007007560A (es) 2007-11-21
AU2005317903C1 (en) 2012-05-10
WO2006067376A3 (en) 2007-07-26
CA2589136C (en) 2015-10-06
KR20070091626A (ko) 2007-09-11
US20090311177A1 (en) 2009-12-17
US7972588B2 (en) 2011-07-05
KR101314460B1 (ko) 2013-10-10
AU2005317903B2 (en) 2011-12-01
RU2007122804A (ru) 2009-01-27
AU2005317903B8 (en) 2012-01-19
AU2005317903A1 (en) 2006-06-29
EP2275145A1 (en) 2011-01-19
US20110236311A1 (en) 2011-09-29
CN105012972A (zh) 2015-11-04
RU2419627C2 (ru) 2011-05-27
WO2006067376A2 (en) 2006-06-29
EP1830890A2 (en) 2007-09-12
CA2817636A1 (en) 2006-06-29
EP2258403A1 (en) 2010-12-08
JP2008528445A (ja) 2008-07-31
NO341638B1 (no) 2017-12-18
JP2012254998A (ja) 2012-12-27
CN101084020A (zh) 2007-12-05
BRPI0519317A2 (pt) 2009-01-13
JP5743372B2 (ja) 2015-07-01
US8679455B2 (en) 2014-03-25
EP2266629B1 (en) 2015-12-09
EP2266629A1 (en) 2010-12-29
NO20073157L (no) 2007-06-20
CA2589136A1 (en) 2006-06-29

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AT Applications terminated before publication under section 16(1)