NO20073157L - Radiolabelling methods - Google Patents

Radiolabelling methods

Info

Publication number
NO20073157L
NO20073157L NO20073157A NO20073157A NO20073157L NO 20073157 L NO20073157 L NO 20073157L NO 20073157 A NO20073157 A NO 20073157A NO 20073157 A NO20073157 A NO 20073157A NO 20073157 L NO20073157 L NO 20073157L
Authority
NO
Norway
Prior art keywords
compound
formula
tomography
labeling methods
relates
Prior art date
Application number
NO20073157A
Other languages
English (en)
Other versions
NO341638B1 (no
Inventor
Matthias Eberhard Glaser
Erik Arstad
Original Assignee
Hammersmith Imanet Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hammersmith Imanet Ltd filed Critical Hammersmith Imanet Ltd
Publication of NO20073157L publication Critical patent/NO20073157L/no
Publication of NO341638B1 publication Critical patent/NO341638B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
    • A61K51/1051—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from breast, e.g. the antibody being herceptin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se

Abstract

Oppfinnelsen dreier seg om radiodiagnostiske og radioterapeutiske midler, blant annet biologisk aktive vektorer merket med radionuklider. Den dreier seg også om framgangsmåter og reagenser som merker en vektor, for eksempel et peptid, og som omfatter å la en forbindelse av formel (I) reagere med en forbindelse av formel (II): eller la en forbindelse av formel (III) reagere med en forbindelse av formel (IV) i nærvær av en Cu(I)-katalysator. De resulterende merkede konjugatene kan brukes som diagnostiske midler, for eksempel som radiofarmasøytika, mer spesifikt til bruk i positronemisjonstomografi (PET) eller datatomografi med utsending av enkeltfotoner (SPECT eller Single Photon Emission Computed Tomography), eller til radioterapi.
NO20073157A 2004-12-22 2007-06-20 Framgangsmåte for å merke en vektor, nye forbindelser og bruk av disse i fremstilling av et radiofarmasøytikum, samt en radiofarmasøytisk sammensetning NO341638B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0428012.9A GB0428012D0 (en) 2004-12-22 2004-12-22 Radiolabelling methods
PCT/GB2005/004729 WO2006067376A2 (en) 2004-12-22 2005-12-09 Radiolabelled conjugates of rgd-containing peptides and methods for their preparation via click-chemistry

Publications (2)

Publication Number Publication Date
NO20073157L true NO20073157L (no) 2007-06-20
NO341638B1 NO341638B1 (no) 2017-12-18

Family

ID=34112991

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20073157A NO341638B1 (no) 2004-12-22 2007-06-20 Framgangsmåte for å merke en vektor, nye forbindelser og bruk av disse i fremstilling av et radiofarmasøytikum, samt en radiofarmasøytisk sammensetning

Country Status (13)

Country Link
US (2) US7972588B2 (no)
EP (4) EP1830890A2 (no)
JP (2) JP5743372B2 (no)
KR (1) KR101314460B1 (no)
CN (2) CN101084020A (no)
AU (1) AU2005317903C1 (no)
BR (1) BRPI0519317A2 (no)
CA (2) CA2589136C (no)
GB (1) GB0428012D0 (no)
MX (1) MX2007007560A (no)
NO (1) NO341638B1 (no)
RU (1) RU2419627C2 (no)
WO (1) WO2006067376A2 (no)

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WO2011079245A1 (en) * 2009-12-23 2011-06-30 Board Of Regents Of The University Of Nebraska Targeted radiolabeled compounds and their use for the treatment and diagnosis of cancer
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US9770515B2 (en) 2010-06-01 2017-09-26 Advanced Proteome Therapeutics Inc. Crosslinking of proteins and other entities via conjugates of α-haloacetophenones, benzyl halides, quinones, and their derivatives
US10434197B2 (en) * 2010-07-23 2019-10-08 University Of Delaware Tetrazine-trans-cyclooctene ligation for the rapid construction of radionuclide labeled probes
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GB201019824D0 (en) 2010-11-23 2011-01-05 Ge Healthcare Ltd Radioiodination method
GB201021369D0 (en) 2010-12-16 2011-01-26 Ge Healthcare Ltd Radioiodinated fatty acids
GB201021517D0 (en) 2010-12-20 2011-02-02 Ge Healthcare Ltd Radioiodinated guanidines
RU2013128360A (ru) 2010-12-22 2015-01-27 ДжиИ ХЕЛТКЕР ЛИМИТЕД Her2-связывающие белки, меченые 18f-содержащим кремнийорганическим соединением
KR102498607B1 (ko) 2010-12-22 2023-02-13 제너럴 일렉트릭 캄파니 방사성표지 ｈｅｒ２ 결합 펩티드
WO2012118909A1 (en) 2011-03-01 2012-09-07 Ge Healthcare Limited Radiolabelled octreotate analogues as pet tracers
US20120251448A1 (en) * 2011-03-03 2012-10-04 Hefti Franz F Compounds for Use in the Detection of Neurodegenerative Diseases
US9023318B2 (en) * 2011-06-08 2015-05-05 Siemens Medical Solutions Usa, Inc. Compounds with matrix-metalloproteinase inhibitory activity and imaging agents thereof
WO2013048832A1 (en) 2011-09-29 2013-04-04 Ge Healthcare Limited 18 f - labelled 6 - ( 2 - fluoroethoxy) - 2 - naphthaldehyde for detecting cancer stem cells
WO2013048811A1 (en) 2011-09-30 2013-04-04 Ge Healthcare Limited Imaging and radiotherapy methods for tumour stem cells
US20140335019A1 (en) * 2011-12-02 2014-11-13 The Regents Of The University Of Michigan Compositions and methods for the treatment and analysis of neurological disorders
GB201121911D0 (en) 2011-12-20 2012-02-01 Ge Healthcare Ltd Radiofluorination method
US20150017093A1 (en) * 2012-02-03 2015-01-15 Aarhus Universitet Radiolabeled bile acids and bile acid derivatives
EP2657213A1 (en) * 2012-04-24 2013-10-30 Institut National de la Santé et de la Recherche Medicale Labelled quinoxaline derivatives as multimodal radiopharmaceuticals and their precursors
US20140065070A1 (en) * 2012-08-28 2014-03-06 Mcmaster University Methods of preparing triazole-containing radioiodinated compounds
US20160137639A1 (en) * 2012-10-26 2016-05-19 Japan Tobacco Inc. Triazole-isoxazole compound and medical use thereof
US20150023877A1 (en) * 2013-07-18 2015-01-22 The Board Of Trustees Of The Leland Stanford Junior University Methods of parkinsons disease diagnosis and monitoring treatment
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Also Published As

Publication number Publication date
RU2007122804A (ru) 2009-01-27
EP1830890A2 (en) 2007-09-12
JP2008528445A (ja) 2008-07-31
EP2275145A1 (en) 2011-01-19
AU2005317903B2 (en) 2011-12-01
NO341638B1 (no) 2017-12-18
US20110236311A1 (en) 2011-09-29
MX2007007560A (es) 2007-11-21
AU2005317903A1 (en) 2006-06-29
WO2006067376A2 (en) 2006-06-29
WO2006067376A3 (en) 2007-07-26
CA2589136A1 (en) 2006-06-29
CN105012972A (zh) 2015-11-04
EP2266629B1 (en) 2015-12-09
US7972588B2 (en) 2011-07-05
CA2817636A1 (en) 2006-06-29
GB0428012D0 (en) 2005-01-26
US20090311177A1 (en) 2009-12-17
JP5743372B2 (ja) 2015-07-01
AU2005317903B8 (en) 2012-01-19
CA2589136C (en) 2015-10-06
KR20070091626A (ko) 2007-09-11
EP2258403A1 (en) 2010-12-08
AU2005317903C1 (en) 2012-05-10
EP2266629A1 (en) 2010-12-29
BRPI0519317A2 (pt) 2009-01-13
JP2012254998A (ja) 2012-12-27
CN101084020A (zh) 2007-12-05
US8679455B2 (en) 2014-03-25
RU2419627C2 (ru) 2011-05-27
KR101314460B1 (ko) 2013-10-10

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Legal Events

Date Code Title Description
CREP Change of representative

Representative=s name: ZACCO NORWAY AS, POSTBOKS 2003 VIKA

CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: GE HEALTHCARE LIMITED, GB

MM1K Lapsed by not paying the annual fees