MX2011010295A - Reactivos de radiomarcado y metodos. - Google Patents

Reactivos de radiomarcado y metodos.

Info

Publication number
MX2011010295A
MX2011010295A MX2011010295A MX2011010295A MX2011010295A MX 2011010295 A MX2011010295 A MX 2011010295A MX 2011010295 A MX2011010295 A MX 2011010295A MX 2011010295 A MX2011010295 A MX 2011010295A MX 2011010295 A MX2011010295 A MX 2011010295A
Authority
MX
Mexico
Prior art keywords
reagents
methods
sup
radiolabelling
radiopharmaceuticals
Prior art date
Application number
MX2011010295A
Other languages
English (en)
Inventor
Joseph Maduabuchi Arukwe
Dag Erland Olberg
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of MX2011010295A publication Critical patent/MX2011010295A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se refiere a reactivos y métodos para [18F]- fluoración de biomoléculas, en particular de péptidos. Los compuestos 18F-marcados resultantes son útiles como radiofarmacéuticos, específicamente para uso en Tomografía de emisión de positrones (PET).
MX2011010295A 2009-03-30 2010-03-22 Reactivos de radiomarcado y metodos. MX2011010295A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16449409P 2009-03-30 2009-03-30
GBGB0905438.8A GB0905438D0 (en) 2009-03-30 2009-03-30 Radiolabelling reagents and methods
PCT/US2010/028078 WO2010114723A1 (en) 2009-03-30 2010-03-22 Radiolabelling reagents and methods

Publications (1)

Publication Number Publication Date
MX2011010295A true MX2011010295A (es) 2012-03-26

Family

ID=40671939

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011010295A MX2011010295A (es) 2009-03-30 2010-03-22 Reactivos de radiomarcado y metodos.

Country Status (15)

Country Link
US (1) US8530620B2 (es)
EP (1) EP2414333B1 (es)
JP (1) JP2012522052A (es)
KR (1) KR20110133038A (es)
CN (2) CN102356069B (es)
AU (1) AU2010232828A1 (es)
BR (1) BRPI1011531A2 (es)
CA (1) CA2757016A1 (es)
ES (1) ES2404346T3 (es)
GB (1) GB0905438D0 (es)
MX (1) MX2011010295A (es)
PL (1) PL2414333T3 (es)
PT (1) PT2414333E (es)
RU (1) RU2524284C2 (es)
WO (1) WO2010114723A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2732632C (en) 2008-08-01 2018-01-09 The Johns Hopkins University Psma-binding agents and uses thereof
EP2648767B1 (en) * 2010-12-09 2023-03-15 GE Healthcare Limited Radiotracer compositions
WO2013048811A1 (en) 2011-09-30 2013-04-04 Ge Healthcare Limited Imaging and radiotherapy methods for tumour stem cells
AR097683A1 (es) * 2013-09-26 2016-04-06 Lilly Co Eli Compuestos y uso para la preparación de agentes de formación de imagen tau y formulaciones para la formación de imagen tau
WO2016030329A1 (en) * 2014-08-24 2016-03-03 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Method for the production of 18f-labeled active esters and their application exemplified by the preparation of a psma-specific pet-tracer
PL3356385T3 (pl) * 2015-09-30 2021-06-28 Deutsches Krebsforschungszentrum Tagowane 18F inhibitory antygenu błonowego specyficznego dla gruczołu krokowego (PSMA) i ich zastosowanie jako środków do obrazowania w nowotworze gruczołu krokowego
GB201518918D0 (en) * 2015-10-26 2015-12-09 Norsk Medisinsk Syklotronsenter As And Uni I Oslo Method
WO2018022603A1 (en) * 2016-07-25 2018-02-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of making 18f-labeled precursors and peptides, labeled c-met binding peptides, and methods of use thereof
US11628229B2 (en) 2017-03-13 2023-04-18 Arizona Board Of Regents On Behalf Of The University Of Arizona Method of synthesizing 18F radiolabeled biomolecular agents
GB202019006D0 (en) 2020-12-02 2021-01-13 Vestlandets Innovasjonsselskap As GFR targeting compounds

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242680A (en) * 1991-08-23 1993-09-07 Merck & Co., Inc. Thiol-reactive maleimido-based radiolabeling reagents
US5346686A (en) * 1992-10-05 1994-09-13 Mallinckrodt Medical, Inc. Labelled interleukin-8 and medical uses thereof
HUP9900459A3 (en) * 1996-01-23 1999-11-29 Rapigene Inc Bothell Methods and compositions for detecting binding of ligand pair using non-fluorescent label
EP0932417B1 (en) * 1996-10-17 2003-03-05 Immunomedics, Inc. Non-antigenic toxin-conjugate and fusion protein of internalizing receptor system
JP3992923B2 (ja) * 1997-09-03 2007-10-17 イムノメディクス， インコーポレイテッド Ｆ−１８陽電子放出トモグラフィー用のタン白及びペプチドのフッ素化方法
US6350360B1 (en) 2000-04-07 2002-02-26 Sandia Coroporation Method of fabricating a 3-dimensional tool master
GB0115927D0 (en) * 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination
WO2003006491A2 (en) * 2001-07-10 2003-01-23 Amersham Health As Peptide-based compounds for targeting intergin receptors
FR2841554B1 (fr) 2002-07-01 2008-01-18 Commissariat Energie Atomique Composes de maleimides marques, leur procede de preparation et leur utilisation pour le marquage de macromolecules
GB0305704D0 (en) 2003-03-13 2003-04-16 Amersham Plc Radiofluorination methods
GB0317815D0 (en) 2003-07-30 2003-09-03 Amersham Health As Imaging agents
GB0329716D0 (en) 2003-12-23 2004-01-28 Amersham Plc Radical trap
GB0420344D0 (en) * 2004-09-14 2004-10-13 Amersham Plc Diagnostic compounds
BRPI0813671A2 (pt) * 2007-06-20 2014-12-30 Ge Healthcare Ltd Métodos para radiofluoração, para gerar uma imagem de um corpo humano ou animal, e para formação de imagem, composto, e, formulação radiofarmacêutica
JP5318874B2 (ja) * 2007-09-10 2013-10-16 ジーイー・ヘルスケア・リミテッド 放射性フッ素化方法
FR2926079B1 (fr) 2008-01-03 2012-12-28 Commissariat Energie Atomique Procede de preparation d'un derive de purine marque, ledit derive et ses utilisations

Also Published As

Publication number Publication date
ES2404346T3 (es) 2013-05-27
RU2524284C2 (ru) 2014-07-27
GB0905438D0 (en) 2009-05-13
BRPI1011531A2 (pt) 2016-03-29
US8530620B2 (en) 2013-09-10
CN102356069A (zh) 2012-02-15
WO2010114723A1 (en) 2010-10-07
CA2757016A1 (en) 2010-10-07
PL2414333T3 (pl) 2013-07-31
CN102356069B (zh) 2014-09-24
RU2011139219A (ru) 2013-05-10
CN104292155A (zh) 2015-01-21
US20120022227A1 (en) 2012-01-26
PT2414333E (pt) 2013-05-07
EP2414333A1 (en) 2012-02-08
KR20110133038A (ko) 2011-12-09
AU2010232828A1 (en) 2011-10-13
EP2414333B1 (en) 2013-02-13
JP2012522052A (ja) 2012-09-20

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