MX2013010012A - Analogos de octreotato radiomarcado como trazadores de tomografia por emision de positrones. - Google Patents

Analogos de octreotato radiomarcado como trazadores de tomografia por emision de positrones.

Info

Publication number
MX2013010012A
MX2013010012A MX2013010012A MX2013010012A MX2013010012A MX 2013010012 A MX2013010012 A MX 2013010012A MX 2013010012 A MX2013010012 A MX 2013010012A MX 2013010012 A MX2013010012 A MX 2013010012A MX 2013010012 A MX2013010012 A MX 2013010012A
Authority
MX
Mexico
Prior art keywords
novel
radiolabelled
pet
pet tracers
radiotracer
Prior art date
Application number
MX2013010012A
Other languages
English (en)
Inventor
Sajinder Kaur Luthra
Julius Leyton
Eric Ofori Aboagye
Lisa Iddon
Bard Indrevoll
Matthias Eberhard Glaser
Alan Cutherbertson
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of MX2013010012A publication Critical patent/MX2013010012A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Nuclear Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describen trazadores radioactivos novedosos para la imagenología de Tomografía por Emisión de Positrones (PET). Se describen trazadores radioactivos novedosos para la imagenología de Tomografía por Emisión de Positrones (PET) de tumores neuroendocrinos. Específicamente, la presente invención describe análogos novedosos de [18F][fluoroetiltriazol-[Tyr3]octreotato; en particular, aquellos que se enfocan en receptores de somatostatina encontrados en la superficie de células de tumores neuroendocrinos gastroenteropancreáticos. La presente invención también describe intermediarios, precursores, composiciones farmacéuticas, métodos de elaboración, y métodos de uso de los trazadores radioactivos novedosos.
MX2013010012A 2011-03-01 2012-03-01 Analogos de octreotato radiomarcado como trazadores de tomografia por emision de positrones. MX2013010012A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161447785P 2011-03-01 2011-03-01
PCT/US2012/027168 WO2012118909A1 (en) 2011-03-01 2012-03-01 Radiolabelled octreotate analogues as pet tracers

Publications (1)

Publication Number Publication Date
MX2013010012A true MX2013010012A (es) 2014-04-14

Family

ID=45841639

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013010012A MX2013010012A (es) 2011-03-01 2012-03-01 Analogos de octreotato radiomarcado como trazadores de tomografia por emision de positrones.

Country Status (11)

Country Link
US (1) US10201625B2 (es)
EP (1) EP2680889B1 (es)
JP (1) JP2014515729A (es)
KR (1) KR20140010096A (es)
CN (1) CN103687627A (es)
AU (1) AU2012223364A1 (es)
CA (1) CA2828810A1 (es)
ES (1) ES2749640T3 (es)
MX (1) MX2013010012A (es)
RU (1) RU2013140291A (es)
WO (1) WO2012118909A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10150804B2 (en) 2014-01-03 2018-12-11 British Columbia Cancer Agency Branch Compositions and methods for imaging cancer
WO2015143019A2 (en) * 2014-03-18 2015-09-24 Mayo Foundation For Medical Education And Research Gaseous f-18 technologies
BR212016030926U2 (pt) 2014-06-30 2018-05-29 Tarveda Therapeutics Inc conjugados de alvo e partículas e formulações dos mesmos
CN106084005B (zh) * 2016-06-15 2020-02-14 广州军区广州总医院 靶向生长抑素受体的Al18F-NOTA-PEG6-TATE及其制备方法和应用
US20180296707A1 (en) * 2017-04-12 2018-10-18 SeeCure Taiwan Co., Ltd. Pharmaceutical formulation and method of preparing the same
AU2018389100A1 (en) * 2017-12-22 2020-07-09 Cornell University 18F-labeled peptide ligands useful in PET and Cerenkov luminescene imaging
EP3820886A4 (en) 2018-05-23 2022-04-06 Provincial Health Services Authority RADIOLABELED MELANOCORTIN-1 RECEPTOR-SPECIFIC ALPHA MELANOCYT-STIMULATING HORMONE ANALOGUES FOR IMAGING OR THERAPY
US11396535B2 (en) 2019-03-01 2022-07-26 Provincial Health Services Authority Cyclic peptide analogs of melanocortin and amanitin and methods of making such
CN114401947A (zh) 2019-06-21 2022-04-26 省卫生服务机构 靶向前列腺特异性膜抗原的放射性标记化合物
CN110407899B (zh) * 2019-07-31 2023-03-31 上海应用技术大学 一种双点击化学联用合成可运用于后聚合改性的含糖衍生物的方法
CN110563809A (zh) * 2019-10-10 2019-12-13 应连心 一种聚乙二醇修饰的奥曲肽及其制备方法
CN112587679B (zh) * 2020-12-02 2022-06-17 北京肿瘤医院(北京大学肿瘤医院) 放射性核素标记生长抑素受体拮抗剂及其制备方法和应用
WO2023062931A1 (ja) * 2021-10-15 2023-04-20 デンカ株式会社 化合物及び当該化合物の製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5432288A (en) * 1991-04-18 1995-07-11 Indiana University Foundation Derivatives of ryanodine and dehydroryanodine
EP1385556A4 (en) * 2001-05-02 2005-10-19 Univ Missouri System At Columb PEPTIDE CONJUGATES WITH AFFINITY FOR GASTRIN RECEPTORS
GB0428012D0 (en) * 2004-12-22 2005-01-26 Hammersmith Imanet Ltd Radiolabelling methods
EP2059491A1 (en) 2006-08-03 2009-05-20 Hammersmith Imanet Limited Method for the purification of radiolabelled compounds
MX2009012386A (es) 2007-05-16 2009-12-03 Ge Healthcare As Agentes de generacion de imagen de peptido.
GB0808833D0 (en) * 2008-05-15 2008-06-18 Ge Healthcare Ltd Biomarkers for depression
RU2535975C2 (ru) 2008-09-05 2014-12-20 Империал Инновейшнз Лимитед Производные изатина для применения в качестве агентов визуализации in vivo

Also Published As

Publication number Publication date
EP2680889B1 (en) 2019-06-19
JP2014515729A (ja) 2014-07-03
CA2828810A1 (en) 2012-09-07
ES2749640T3 (es) 2020-03-23
AU2012223364A1 (en) 2013-09-19
CN103687627A (zh) 2014-03-26
KR20140010096A (ko) 2014-01-23
WO2012118909A1 (en) 2012-09-07
RU2013140291A (ru) 2015-04-10
EP2680889A1 (en) 2014-01-08
US10201625B2 (en) 2019-02-12
US20130343990A1 (en) 2013-12-26

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