DE60312136D1 - Radiofluorierungsverfahren - Google Patents

Radiofluorierungsverfahren

Info

Publication number
DE60312136D1
DE60312136D1 DE60312136T DE60312136T DE60312136D1 DE 60312136 D1 DE60312136 D1 DE 60312136D1 DE 60312136 T DE60312136 T DE 60312136T DE 60312136 T DE60312136 T DE 60312136T DE 60312136 D1 DE60312136 D1 DE 60312136D1
Authority
DE
Germany
Prior art keywords
sup
compound
formula
radiofluorierungsverfahren
radiopharmaceuticals
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60312136T
Other languages
English (en)
Other versions
DE60312136T2 (de
Inventor
Alan Cuthbertson
Magne Solbakken
Joseph Maduabuchi Arukwe
Hege Karlsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare Ltd
Original Assignee
GE Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Ltd filed Critical GE Healthcare Ltd
Publication of DE60312136D1 publication Critical patent/DE60312136D1/de
Application granted granted Critical
Publication of DE60312136T2 publication Critical patent/DE60312136T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008—Peptides; Proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60312136T 2002-03-22 2003-03-20 Radiofluorierungsverfahren Expired - Lifetime DE60312136T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0206750.2A GB0206750D0 (en) 2002-03-22 2002-03-22 Radiofluorination methods
GB0206750 2002-03-22
PCT/GB2003/001332 WO2003080544A1 (en) 2002-03-22 2003-03-20 Radiofluorination methods

Publications (2)

Publication Number Publication Date
DE60312136D1 true DE60312136D1 (de) 2007-04-12
DE60312136T2 DE60312136T2 (de) 2007-11-15

Family

ID=9933482

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60312136T Expired - Lifetime DE60312136T2 (de) 2002-03-22 2003-03-20 Radiofluorierungsverfahren

Country Status (9)

Country Link
US (2) US7368474B2 (de)
EP (1) EP1487762B1 (de)
JP (1) JP4365223B2 (de)
AT (1) ATE355259T1 (de)
AU (1) AU2003214446A1 (de)
DE (1) DE60312136T2 (de)
ES (1) ES2282607T3 (de)
GB (1) GB0206750D0 (de)
WO (1) WO2003080544A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0305704D0 (en) * 2003-03-13 2003-04-16 Amersham Plc Radiofluorination methods
NO20033115D0 (no) * 2003-07-08 2003-07-08 Amersham Health As Peptid-baserte forbindelser
GB0329716D0 (en) * 2003-12-23 2004-01-28 Amersham Plc Radical trap
US7763234B2 (en) 2004-03-04 2010-07-27 Ge Healthcare As Pharmaceutical compounds
CA2568601A1 (en) * 2004-06-16 2005-12-29 Ge Healthcare As Peptide-based compounds
US20080095704A1 (en) * 2004-07-02 2008-04-24 Alan Cuthbertson Imaging Agents with Improved Pharmacokinetic Profiles
GB0420344D0 (en) * 2004-09-14 2004-10-13 Amersham Plc Diagnostic compounds
RU2007118385A (ru) 2004-11-22 2008-12-27 Джи-И Хелткер АС (NO) Контрастные агенты для направлений доставки во внеклеточный матрикс
GB0524987D0 (en) 2005-12-08 2006-01-18 Ge Healthcare Ltd Novel imaging agents for fibrosis
US8080815B2 (en) * 2006-05-26 2011-12-20 Abt Molecular Imaging, Inc. Biomarker generator
EP2063918B1 (de) 2006-09-08 2014-02-26 Piramal Imaging SA Verbindungen und verfahren für 18f-markierte mittel
AU2007304508A1 (en) * 2006-10-02 2008-04-10 Bayer Schering Pharma Aktiengesellschaft Silicon derivatives for pet imaging
EP2114464A2 (de) * 2006-12-28 2009-11-11 GE Healthcare AS Radiofluorinationsverfahren
CN101723847B (zh) * 2008-10-10 2013-01-16 北京师范大学 一类18f标记对硝基苯甲酰基氨基酸类化合物及其制备方法和应用
US8293208B2 (en) 2009-05-15 2012-10-23 The Governors Of The University Of Alberta Fluorinated fructose derivatives for PET imaging
US8273300B2 (en) * 2009-07-09 2012-09-25 Siemens Medical Solutions Usa, Inc. Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure
US8435454B2 (en) * 2009-07-09 2013-05-07 Siemens Medical Solutions Usa, Inc. Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure
KR101229929B1 (ko) 2010-05-28 2013-02-05 서강대학교산학협력단 1,2,3-트리아졸기를 갖는 새로운 말레이미드 화합물, 이의 제조방법 및 이를 보결그룹으로 하는 생체화합물의 ｆ­18 표지방법
WO2012033374A2 (ko) * 2010-09-09 2012-03-15 서강대학교 산학협력단 1,2,3-트리아졸륨 염을 갖는 설포네이트 전구체, 그 제조방법 및 이를 사용하는 분자내 친핵성 플루오르화반응
WO2013048832A1 (en) 2011-09-29 2013-04-04 Ge Healthcare Limited 18 f - labelled 6 - ( 2 - fluoroethoxy) - 2 - naphthaldehyde for detecting cancer stem cells
WO2013048811A1 (en) 2011-09-30 2013-04-04 Ge Healthcare Limited Imaging and radiotherapy methods for tumour stem cells

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE87290T1 (de) 1985-05-17 1993-04-15 Neorx Corp Radiohalogenierte kleine molekuele fuer das markieren von proteinen.
US4876081A (en) 1987-04-16 1989-10-24 Neorx Corporation Vinyl substituted radiohalogen and methods of use conjugates
US5144043A (en) * 1988-06-15 1992-09-01 Centocor Cleavable bifunctional coupling agents
US5144053A (en) * 1991-03-25 1992-09-01 Ethyl Corporation Aluminum alkyls and linear 1-olefins from internal olefins
DE19621177A1 (de) * 1996-05-24 1997-11-27 Basf Ag Kohlenhydratderivate und ihre Synthese an fester Phase
CA2302360C (en) * 1997-09-03 2005-11-15 Immunomedics, Inc. Fluorination of proteins and peptides for f-18 positron emission tomography
US6350360B1 (en) 2000-04-07 2002-02-26 Sandia Coroporation Method of fabricating a 3-dimensional tool master
CA2452923C (en) 2001-07-10 2012-02-07 Amersham Health As Peptide-based compounds for targeting integrin receptors
GB0317815D0 (en) * 2003-07-30 2003-09-03 Amersham Health As Imaging agents

Also Published As

Publication number Publication date
EP1487762A1 (de) 2004-12-22
JP4365223B2 (ja) 2009-11-18
US20080274052A1 (en) 2008-11-06
JP2005520857A (ja) 2005-07-14
DE60312136T2 (de) 2007-11-15
EP1487762B1 (de) 2007-02-28
AU2003214446A1 (en) 2003-10-08
US7368474B2 (en) 2008-05-06
ES2282607T3 (es) 2007-10-16
ATE355259T1 (de) 2006-03-15
WO2003080544A1 (en) 2003-10-02
US20050142061A1 (en) 2005-06-30
GB0206750D0 (en) 2002-05-01

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