ATE87290T1 - Radiohalogenierte kleine molekuele fuer das markieren von proteinen. - Google Patents
Radiohalogenierte kleine molekuele fuer das markieren von proteinen.Info
- Publication number
- ATE87290T1 ATE87290T1 AT86303757T AT86303757T ATE87290T1 AT E87290 T1 ATE87290 T1 AT E87290T1 AT 86303757 T AT86303757 T AT 86303757T AT 86303757 T AT86303757 T AT 86303757T AT E87290 T1 ATE87290 T1 AT E87290T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- compounds
- small molecules
- radiohalogenated
- metalated
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 150000003384 small molecules Chemical class 0.000 title abstract 2
- 238000002372 labelling Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000000524 functional group Chemical group 0.000 abstract 2
- 125000002524 organometallic group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000021615 conjugation Effects 0.000 abstract 1
- 238000007324 demetalation reaction Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 125000003106 haloaryl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- BRMYZIKAHFEUFJ-UHFFFAOYSA-L mercury diacetate Chemical compound CC(=O)O[Hg]OC(C)=O BRMYZIKAHFEUFJ-UHFFFAOYSA-L 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/10—Mercury compounds
- C07F3/12—Aromatic substances containing mercury
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73539285A | 1985-05-17 | 1985-05-17 | |
| US85274086A | 1986-04-21 | 1986-04-21 | |
| EP86303757A EP0203764B1 (de) | 1985-05-17 | 1986-05-16 | Radiohalogenierte kleine Moleküle für das Markieren von Proteinen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE87290T1 true ATE87290T1 (de) | 1993-04-15 |
Family
ID=27112875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86303757T ATE87290T1 (de) | 1985-05-17 | 1986-05-16 | Radiohalogenierte kleine molekuele fuer das markieren von proteinen. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0203764B1 (de) |
| AT (1) | ATE87290T1 (de) |
| DE (1) | DE3688103T2 (de) |
| DK (1) | DK226986A (de) |
| NO (1) | NO861962L (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4812577A (en) * | 1987-04-28 | 1989-03-14 | The United States Of America As Represented By The United States Department Of Energy | Mercuric acetate phenyl maleimide useful for preparing radiohalogenated maleimides |
| US4977288A (en) * | 1988-01-29 | 1990-12-11 | President And Fellows Of Harvard College | M-aminophenyltrialkylstannane |
| US5059541A (en) * | 1988-04-29 | 1991-10-22 | Neorx Corporation | Minimal derivatization of proteins |
| US4966999A (en) * | 1988-06-07 | 1990-10-30 | Cytogen Corporation | Radiohalogenated compounds for site specific labeling |
| EP0434765B1 (de) * | 1988-09-30 | 1995-11-08 | Neorx Corporation | Wässrige additivsysteme, verfahren und polymerteilchen |
| US5066789A (en) * | 1988-09-30 | 1991-11-19 | Neorx Corporation | Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages |
| US5102651A (en) * | 1989-12-29 | 1992-04-07 | Neorx Corporation | Process for isolation and radiolabeling of pharmaceuticals with isotopes of astatine |
| US5463080A (en) * | 1992-08-27 | 1995-10-31 | Bracco International B.V. | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents |
| GB0206750D0 (en) | 2002-03-22 | 2002-05-01 | Amersham Plc | Radiofluorination methods |
| EP3157577B8 (de) | 2014-06-18 | 2020-12-23 | Alpha Therapy Solutions AB | Automatische verfahrensplattform zur herstellung von astatine-211[at-211]-radiopharmazeutika |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3979506A (en) * | 1974-10-11 | 1976-09-07 | Pierce Chemical Company | Radioactive compounds for labeling proteins |
| EP0011858B1 (de) | 1978-11-29 | 1983-05-18 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Radiojodierte Amine, ihre Herstellung und ihre Verwendung zum Sichtbarmachen des Gehirns |
| DE2947500C2 (de) | 1979-11-24 | 1984-05-10 | Dutschka, Klaus, 4300 Essen | Radiojodierte ω -Phenylfettsäuren, ihre Herstellung und deren Verwendung zur szintigraphischen Untersuchung des Herzmuskels und der Leber |
-
1986
- 1986-05-16 AT AT86303757T patent/ATE87290T1/de not_active IP Right Cessation
- 1986-05-16 NO NO861962A patent/NO861962L/no unknown
- 1986-05-16 DK DK226986A patent/DK226986A/da unknown
- 1986-05-16 EP EP86303757A patent/EP0203764B1/de not_active Expired - Lifetime
- 1986-05-16 DE DE8686303757T patent/DE3688103T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3688103T2 (de) | 1993-07-15 |
| EP0203764A3 (en) | 1990-03-28 |
| DK226986D0 (da) | 1986-05-16 |
| DK226986A (da) | 1986-11-18 |
| NO861962L (no) | 1986-11-18 |
| EP0203764A2 (de) | 1986-12-03 |
| EP0203764B1 (de) | 1993-03-24 |
| DE3688103D1 (de) | 1993-04-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE70268T1 (de) | Stickstoffhaltige heterocyclen. | |
| ES2020981B3 (es) | Fenilsulfonamidas sustituidas. | |
| MY102236A (en) | New aryl derivatives | |
| DE3789839D1 (de) | Herstellung von Enzymen mit geänderter Aktivität. | |
| ATE87290T1 (de) | Radiohalogenierte kleine molekuele fuer das markieren von proteinen. | |
| ES514903A0 (es) | Procedimiento para mejorar la estabilidad en el tiempo de compuestos polihidroxilicos. | |
| ES2041249T3 (es) | Preparaciones liquidas de 1,2-benzoisotiazolin-3-ona, su obtencion y empleo. | |
| BG44537A3 (en) | Method for preparing of 2- amino- 3- ethoxycarbonylamino- 6- (p- fluor- benzylamino)- piridine gluconate | |
| EP0204523A3 (en) | Glucose-6-phosphate dehydrogenase conjugates, their preparation and use | |
| DK162839C (da) | N,3-diacyl-2-oxindol-1-carboxamid-forbindelser og 3-acyl-2-oxindol-forbindelser til anvendelse som mellemprodukter ved deres fremstilling | |
| DK7286A (da) | Octahydroindoliziner | |
| KR880013929A (ko) | 신규 5-메톡시 알킬 암노늄 테트라히드로푸란 및 테트라히드로티오펜 | |
| AU581101B2 (en) | Anti-tumour platinum complexes, their preparation and their use | |
| PT83921B (pt) | Processo para a preparacao de composicoes farmaceuticas e/ou veterinarias contendo derivados de isoxantopterina-8(1'-beta-aldo-glicosidilo)com efeito de modulacao das respostas celulares de animais | |
| KR840007656A (ko) | 살충제 조성물 | |
| JPS54135766A (en) | N-acyloxyimide derivative | |
| KR860007258A (ko) | 이미다조[4,5-c]피리딘의 제조방법 | |
| ES410662A1 (es) | Procedimiento para la preparacion de derivados de acido ni-trofuriltriazolo(4,3-b)piridazin-carboxilico. | |
| ES476164A1 (es) | Procedimiento para la preparacion de nuevos derivados espec-tinomicinicos. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |