DK56687D0 - 5-substitueret octahydroindolizinforbindelser samt 7-ketomellemprodukter ved fremstillingen heraf - Google Patents

5-substitueret octahydroindolizinforbindelser samt 7-ketomellemprodukter ved fremstillingen heraf

Info

Publication number
DK56687D0
DK56687D0 DK056687A DK56687A DK56687D0 DK 56687 D0 DK56687 D0 DK 56687D0 DK 056687 A DK056687 A DK 056687A DK 56687 A DK56687 A DK 56687A DK 56687 D0 DK56687 D0 DK 56687D0
Authority
DK
Denmark
Prior art keywords
ketomel
octahydroindolizin
substituted
compounds
intermediate products
Prior art date
Application number
DK056687A
Other languages
English (en)
Other versions
DK56687A (da
Inventor
Richard Joel Carmosin
John Robert Carson
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of DK56687D0 publication Critical patent/DK56687D0/da
Publication of DK56687A publication Critical patent/DK56687A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK056687A 1986-02-04 1987-02-03 5-substitueret octahydroindolizinforbindelser samt 7-ketomellemprodukter ved fremstillingen heraf DK56687A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/826,167 US4689329A (en) 1986-02-04 1986-02-04 5-substituted octahydroindolizine analgesics compounds and 7-keto intermediates

Publications (2)

Publication Number Publication Date
DK56687D0 true DK56687D0 (da) 1987-02-03
DK56687A DK56687A (da) 1987-08-05

Family

ID=25245878

Family Applications (1)

Application Number Title Priority Date Filing Date
DK056687A DK56687A (da) 1986-02-04 1987-02-03 5-substitueret octahydroindolizinforbindelser samt 7-ketomellemprodukter ved fremstillingen heraf

Country Status (18)

Country Link
US (1) US4689329A (da)
EP (1) EP0237169B1 (da)
JP (1) JPS62215587A (da)
KR (1) KR870007930A (da)
CN (1) CN87101647A (da)
AT (1) ATE77950T1 (da)
AU (1) AU610492B2 (da)
CA (1) CA1288430C (da)
DE (1) DE3780191T2 (da)
DK (1) DK56687A (da)
ES (1) ES2041679T3 (da)
FI (1) FI870460A (da)
GR (1) GR3005131T3 (da)
HU (1) HU196797B (da)
IE (1) IE870277L (da)
NO (1) NO870423L (da)
NZ (1) NZ219052A (da)
ZA (1) ZA87773B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683239A (en) * 1986-04-10 1987-07-28 Mcneilab, Inc. 3-diphenyl substituted octahydroindolizine analgesic compounds
US4800207A (en) * 1987-11-02 1989-01-24 Mcneilab, Inc. Hexahydropyrrolizine compounds useful as analgesics
US5508424A (en) * 1993-03-26 1996-04-16 Ortho Pharmaceutical Corporation 4-arylisoindole analgesics
GB9314973D0 (en) * 1993-07-20 1993-09-01 Smithkline Beecham Plc Medicaments
US5543530A (en) * 1993-12-23 1996-08-06 Ortho Pharmaceutical Corporation 4-arylisoindole analgesics
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
AU2001292936A1 (en) * 2000-09-22 2002-04-02 Ortho-Mcneil Pharmaceutical, Inc. Octahydro-indolizines and quinolizines and hexahydro-pyrrolizines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4205074A (en) * 1977-05-16 1980-05-27 Hokuriku Pharmaceutical Co., Ltd. Anti-spasmodic substituted quinolizidine and indolizidine compounds
EP0067565A1 (en) * 1981-06-16 1982-12-22 Beecham Group Plc Pharmaceutically active compounds
EP0094744A1 (en) * 1982-04-23 1983-11-23 Beecham Group Plc Azabicyclobenzamides, their preparation and their pharmaceutical compositions
AU577435B2 (en) * 1985-01-09 1988-09-22 Mcneilab, Inc. Octahydroindolizine compounds
US4582836A (en) * 1985-01-09 1986-04-15 Mcneilab, Inc. Octahydroindolizine compounds useful as analgesics

Also Published As

Publication number Publication date
CA1288430C (en) 1991-09-03
NO870423D0 (no) 1987-02-03
IE870277L (en) 1987-08-04
HUT45250A (en) 1988-06-28
ES2041679T3 (es) 1993-12-01
US4689329A (en) 1987-08-25
CN87101647A (zh) 1987-09-16
KR870007930A (ko) 1987-09-23
FI870460A0 (fi) 1987-02-03
GR3005131T3 (da) 1993-05-24
NZ219052A (en) 1988-11-29
FI870460A (fi) 1987-08-05
AU610492B2 (en) 1991-05-23
ZA87773B (en) 1988-10-26
EP0237169B1 (en) 1992-07-08
DE3780191D1 (de) 1992-08-13
AU6826887A (en) 1987-08-06
JPS62215587A (ja) 1987-09-22
EP0237169A1 (en) 1987-09-16
DE3780191T2 (de) 1992-12-24
HU196797B (en) 1989-01-30
NO870423L (no) 1987-08-05
DK56687A (da) 1987-08-05
ATE77950T1 (de) 1992-07-15

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