DK165109C - 4-anilino-cyklopentaoedaapyrimidinderivater samt farmaceutiske midler indeholdende saadanne - Google Patents

4-anilino-cyklopentaoedaapyrimidinderivater samt farmaceutiske midler indeholdende saadanne

Info

Publication number
DK165109C
DK165109C DK106586A DK106586A DK165109C DK 165109 C DK165109 C DK 165109C DK 106586 A DK106586 A DK 106586A DK 106586 A DK106586 A DK 106586A DK 165109 C DK165109 C DK 165109C
Authority
DK
Denmark
Prior art keywords
sup
cyclopentaeeda
anilino
products
pharmaceutical agents
Prior art date
Application number
DK106586A
Other languages
English (en)
Other versions
DK106586D0 (da
DK165109B (da
DK106586A (da
Inventor
Nobuyoshi Iwata
Isao Nakayama
Kanichi Nakamura
Tomio Kimura
Takashi Kobayashi
Original Assignee
Sankyo Co
Ube Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co, Ube Industries filed Critical Sankyo Co
Publication of DK106586D0 publication Critical patent/DK106586D0/da
Publication of DK106586A publication Critical patent/DK106586A/da
Publication of DK165109B publication Critical patent/DK165109B/da
Application granted granted Critical
Publication of DK165109C publication Critical patent/DK165109C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Dental Preparations (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Luminescent Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Soil Working Implements (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Eyeglasses (AREA)
DK106586A 1985-03-07 1986-03-07 4-anilino-cyklopentaoedaapyrimidinderivater samt farmaceutiske midler indeholdende saadanne DK165109C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4362685 1985-03-07
JP4362685 1985-03-07

Publications (4)

Publication Number Publication Date
DK106586D0 DK106586D0 (da) 1986-03-07
DK106586A DK106586A (da) 1986-09-08
DK165109B DK165109B (da) 1992-10-12
DK165109C true DK165109C (da) 1993-03-01

Family

ID=12669058

Family Applications (1)

Application Number Title Priority Date Filing Date
DK106586A DK165109C (da) 1985-03-07 1986-03-07 4-anilino-cyklopentaoedaapyrimidinderivater samt farmaceutiske midler indeholdende saadanne

Country Status (15)

Country Link
US (1) US4749704A (da)
EP (1) EP0194161B1 (da)
JP (1) JPS6270A (da)
KR (1) KR890003839B1 (da)
AT (1) ATE106077T1 (da)
AU (1) AU580391B2 (da)
CA (1) CA1273632A (da)
DE (1) DE3689848T2 (da)
DK (1) DK165109C (da)
ES (3) ES8704905A1 (da)
FI (1) FI88717C (da)
HK (1) HK1005450A1 (da)
IE (1) IE64504B1 (da)
NO (1) NO168767C (da)
ZA (1) ZA861708B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5037980A (en) * 1988-04-18 1991-08-06 American Cyanamid Company Phenyl imidazo[1,2-a]pyrimidines
US5877178A (en) * 1991-04-08 1999-03-02 Duquesne University Of The Holy Ghost Pyrimidine derivatives and methods of making and using these derivatives
US5234936A (en) * 1991-10-24 1993-08-10 American Home Products Corporation Pyrimidocycloalkanes as a ii antagonists
EP1656354B1 (en) * 2003-08-12 2007-09-26 F.Hoffmann-La Roche Ag Tetrahydroquinazoline derivatives as cfr antagonists
EP1942069A4 (en) 2005-10-26 2013-01-09 Mitsubishi Electric Corp ELEVATOR GROUP MANAGEMENT AND CONTROL APPARATUS
PT2049500E (pt) 2006-07-06 2011-12-23 Array Biopharma Inc Ciclopenta[d]pirimidinas como inibidores da proteína quinase akt
JP5231411B2 (ja) 2006-07-06 2013-07-10 アレイ バイオファーマ、インコーポレイテッド Aktプロテインキナーゼ阻害剤としてのジヒドロチエノピリミジン
CA2656566C (en) 2006-07-06 2014-06-17 Array Biopharma Inc. Dihydrofuro pyrimidines as akt protein kinase inhibitors
US8063050B2 (en) 2006-07-06 2011-11-22 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
WO2008021456A2 (en) * 2006-08-16 2008-02-21 Cytovia, Inc. N-aryl-5,7-dihydrofuro[3,4-d]pyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof
US8846683B2 (en) 2007-07-05 2014-09-30 Array Biopharma, Inc. Pyrimidyl cyclopentanes as Akt protein kinase inhibitors
KR20150089099A (ko) 2007-07-05 2015-08-04 어레이 바이오파마 인크. Akt 단백질 키나제 억제제로서의 피리미딜 시클로펜탄
US9409886B2 (en) 2007-07-05 2016-08-09 Array Biopharma Inc. Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
CN101918373B (zh) 2007-07-05 2013-06-05 阵列生物制药公司 作为akt蛋白激酶抑制剂的嘧啶基环戊烷
EP2247578B1 (en) 2008-01-09 2013-05-22 Array Biopharma, Inc. Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitors
ES2401685T3 (es) 2008-01-09 2013-04-23 Array Biopharma, Inc. Pirimidil ciclopentano hidroxilado como inhibidor de la proteína quinasa AKT
DE112009002588B4 (de) 2008-10-20 2019-08-14 Mitsubishi Electric Corporation Aufzuggruppenverwaltungssystem
JP6147246B2 (ja) 2011-04-01 2017-06-14 ジェネンテック, インコーポレイテッド Akt及びmek阻害剤化合物の組み合わせ、及び使用方法
EP2694072B1 (en) 2011-04-01 2017-11-29 Genentech, Inc. Combination of akt inhibitor compound and abiraterone for use in therapeutic treatments
GB201121127D0 (en) 2011-12-08 2012-01-18 Dow Corning Treatment of filler with silane
CN111303053B (zh) * 2020-03-16 2023-01-17 中国海洋大学 环戊并[d]嘧啶类化合物及其药学上可接受的盐、溶剂合物或者前药以及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470182A (en) * 1967-02-09 1969-09-30 Sandoz Ag 4-amino-substituted quinazolines
US3980650A (en) * 1972-05-05 1976-09-14 N.V. Koninklijke Pharmaceutische Fabrieken V/H Brocades-Stheeman En Pharmacia 4-Amino-pyrimidine derivatives
US3915976A (en) * 1972-09-01 1975-10-28 Sandoz Ag Substituted-4-phenyl-5h-cycloalkano(d)pyrimidines
PH20344A (en) * 1981-01-29 1986-12-04 Sankyo Co Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them
JPS57203072A (en) * 1981-06-05 1982-12-13 Sankyo Co Ltd 4-anilinopyrimidine derivative, its preparation, antidepressant comprising it as active ingredient

Also Published As

Publication number Publication date
ZA861708B (en) 1986-11-26
JPS6270A (ja) 1987-01-06
DK106586D0 (da) 1986-03-07
FI860969A (fi) 1986-09-08
ATE106077T1 (de) 1994-06-15
DE3689848T2 (de) 1995-01-12
IE64504B1 (en) 1995-08-09
DK165109B (da) 1992-10-12
ES8704905A1 (es) 1987-04-16
US4749704A (en) 1988-06-07
CA1273632A (en) 1990-09-04
AU580391B2 (en) 1989-01-12
KR890003839B1 (ko) 1989-10-05
DE3689848D1 (de) 1994-06-30
FI860969A0 (fi) 1986-03-07
FI88717B (fi) 1993-03-15
EP0194161B1 (en) 1994-05-25
NO860852L (no) 1986-09-08
ES8801221A1 (es) 1988-01-01
FI88717C (fi) 1993-06-28
HK1005450A1 (en) 1999-01-08
NO168767B (no) 1991-12-23
KR860007221A (ko) 1986-10-08
AU5448186A (en) 1986-09-11
ES557198A0 (es) 1988-01-01
EP0194161A2 (en) 1986-09-10
IE860597L (en) 1986-09-07
ES552796A0 (es) 1987-04-16
EP0194161A3 (en) 1987-09-02
ES8801222A1 (es) 1988-01-01
DK106586A (da) 1986-09-08
NO168767C (no) 1992-04-01
ES557199A0 (es) 1988-01-01

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Legal Events

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