NO870423D0 - 5-substituert octahydroindolizin-analgetika-forbindelser og 7-keto-mellomprodukt. - Google Patents

5-substituert octahydroindolizin-analgetika-forbindelser og 7-keto-mellomprodukt.

Info

Publication number
NO870423D0
NO870423D0 NO870423A NO870423A NO870423D0 NO 870423 D0 NO870423 D0 NO 870423D0 NO 870423 A NO870423 A NO 870423A NO 870423 A NO870423 A NO 870423A NO 870423 D0 NO870423 D0 NO 870423D0
Authority
NO
Norway
Prior art keywords
octahydroindolizin
substituted
keto intermediate
analgetic
compounds
Prior art date
Application number
NO870423A
Other languages
English (en)
Other versions
NO870423L (no
Inventor
Richard Joel Carmosin
John Robert Carson
Original Assignee
Mcneilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneilab Inc filed Critical Mcneilab Inc
Publication of NO870423D0 publication Critical patent/NO870423D0/no
Publication of NO870423L publication Critical patent/NO870423L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO870423A 1986-02-04 1987-02-03 5-substituerte oktahydroindolizin-analgetiske forbindelser og 7-keto mellomprodukter. NO870423L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/826,167 US4689329A (en) 1986-02-04 1986-02-04 5-substituted octahydroindolizine analgesics compounds and 7-keto intermediates

Publications (2)

Publication Number Publication Date
NO870423D0 true NO870423D0 (no) 1987-02-03
NO870423L NO870423L (no) 1987-08-05

Family

ID=25245878

Family Applications (1)

Application Number Title Priority Date Filing Date
NO870423A NO870423L (no) 1986-02-04 1987-02-03 5-substituerte oktahydroindolizin-analgetiske forbindelser og 7-keto mellomprodukter.

Country Status (18)

Country Link
US (1) US4689329A (no)
EP (1) EP0237169B1 (no)
JP (1) JPS62215587A (no)
KR (1) KR870007930A (no)
CN (1) CN87101647A (no)
AT (1) ATE77950T1 (no)
AU (1) AU610492B2 (no)
CA (1) CA1288430C (no)
DE (1) DE3780191T2 (no)
DK (1) DK56687A (no)
ES (1) ES2041679T3 (no)
FI (1) FI870460A (no)
GR (1) GR3005131T3 (no)
HU (1) HU196797B (no)
IE (1) IE870277L (no)
NO (1) NO870423L (no)
NZ (1) NZ219052A (no)
ZA (1) ZA87773B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683239A (en) * 1986-04-10 1987-07-28 Mcneilab, Inc. 3-diphenyl substituted octahydroindolizine analgesic compounds
US4800207A (en) * 1987-11-02 1989-01-24 Mcneilab, Inc. Hexahydropyrrolizine compounds useful as analgesics
US5508424A (en) * 1993-03-26 1996-04-16 Ortho Pharmaceutical Corporation 4-arylisoindole analgesics
GB9314973D0 (en) * 1993-07-20 1993-09-01 Smithkline Beecham Plc Medicaments
US5543530A (en) * 1993-12-23 1996-08-06 Ortho Pharmaceutical Corporation 4-arylisoindole analgesics
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
JP2004510712A (ja) * 2000-09-22 2004-04-08 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド オクタヒドロ−インドリジンおよびキノリジンおよびヘキサヒドロ−ピロリジン

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4205074A (en) * 1977-05-16 1980-05-27 Hokuriku Pharmaceutical Co., Ltd. Anti-spasmodic substituted quinolizidine and indolizidine compounds
EP0067565A1 (en) * 1981-06-16 1982-12-22 Beecham Group Plc Pharmaceutically active compounds
EP0094744A1 (en) * 1982-04-23 1983-11-23 Beecham Group Plc Azabicyclobenzamides, their preparation and their pharmaceutical compositions
US4582836A (en) * 1985-01-09 1986-04-15 Mcneilab, Inc. Octahydroindolizine compounds useful as analgesics
AU577435B2 (en) * 1985-01-09 1988-09-22 Mcneilab, Inc. Octahydroindolizine compounds

Also Published As

Publication number Publication date
ZA87773B (en) 1988-10-26
GR3005131T3 (no) 1993-05-24
IE870277L (en) 1987-08-04
AU610492B2 (en) 1991-05-23
DK56687D0 (da) 1987-02-03
EP0237169B1 (en) 1992-07-08
AU6826887A (en) 1987-08-06
KR870007930A (ko) 1987-09-23
US4689329A (en) 1987-08-25
JPS62215587A (ja) 1987-09-22
ATE77950T1 (de) 1992-07-15
HUT45250A (en) 1988-06-28
ES2041679T3 (es) 1993-12-01
CN87101647A (zh) 1987-09-16
FI870460A0 (fi) 1987-02-03
NZ219052A (en) 1988-11-29
DE3780191T2 (de) 1992-12-24
HU196797B (en) 1989-01-30
NO870423L (no) 1987-08-05
CA1288430C (en) 1991-09-03
DK56687A (da) 1987-08-05
DE3780191D1 (de) 1992-08-13
FI870460A (fi) 1987-08-05
EP0237169A1 (en) 1987-09-16

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