DK226986A - Radiohalogenerede smaa molekyler til proteinmaerkning - Google Patents
Radiohalogenerede smaa molekyler til proteinmaerkning Download PDFInfo
- Publication number
- DK226986A DK226986A DK226986A DK226986A DK226986A DK 226986 A DK226986 A DK 226986A DK 226986 A DK226986 A DK 226986A DK 226986 A DK226986 A DK 226986A DK 226986 A DK226986 A DK 226986A
- Authority
- DK
- Denmark
- Prior art keywords
- protein
- compounds
- small molecules
- metalated
- functional group
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 5
- 108090000623 proteins and genes Proteins 0.000 title abstract 5
- 150000003384 small molecules Chemical class 0.000 title abstract 2
- 238000002372 labelling Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000000524 functional group Chemical group 0.000 abstract 2
- 125000002524 organometallic group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000021615 conjugation Effects 0.000 abstract 1
- 238000007324 demetalation reaction Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 125000003106 haloaryl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- BRMYZIKAHFEUFJ-UHFFFAOYSA-L mercury diacetate Chemical compound CC(=O)O[Hg]OC(C)=O BRMYZIKAHFEUFJ-UHFFFAOYSA-L 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
- C07F3/10—Mercury compounds
- C07F3/12—Aromatic substances containing mercury
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73539285A | 1985-05-17 | 1985-05-17 | |
| US85274086A | 1986-04-21 | 1986-04-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK226986D0 DK226986D0 (da) | 1986-05-16 |
| DK226986A true DK226986A (da) | 1986-11-18 |
Family
ID=27112875
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK226986A DK226986A (da) | 1985-05-17 | 1986-05-16 | Radiohalogenerede smaa molekyler til proteinmaerkning |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0203764B1 (da) |
| AT (1) | ATE87290T1 (da) |
| DE (1) | DE3688103T2 (da) |
| DK (1) | DK226986A (da) |
| NO (1) | NO861962L (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4812577A (en) * | 1987-04-28 | 1989-03-14 | The United States Of America As Represented By The United States Department Of Energy | Mercuric acetate phenyl maleimide useful for preparing radiohalogenated maleimides |
| US4977288A (en) * | 1988-01-29 | 1990-12-11 | President And Fellows Of Harvard College | M-aminophenyltrialkylstannane |
| US5059541A (en) * | 1988-04-29 | 1991-10-22 | Neorx Corporation | Minimal derivatization of proteins |
| US4966999A (en) * | 1988-06-07 | 1990-10-30 | Cytogen Corporation | Radiohalogenated compounds for site specific labeling |
| US5066789A (en) * | 1988-09-30 | 1991-11-19 | Neorx Corporation | Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages |
| JPH04504248A (ja) * | 1988-09-30 | 1992-07-30 | ネオロクス コーポレーション | シッフ塩基で結合した、ターゲティング物質―診断／治療薬複合体 |
| US5102651A (en) * | 1989-12-29 | 1992-04-07 | Neorx Corporation | Process for isolation and radiolabeling of pharmaceuticals with isotopes of astatine |
| US5463080A (en) * | 1992-08-27 | 1995-10-31 | Bracco International B.V. | 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents |
| GB0206750D0 (en) | 2002-03-22 | 2002-05-01 | Amersham Plc | Radiofluorination methods |
| JP6830435B2 (ja) | 2014-06-18 | 2021-02-17 | リンデグレン、ストゥーレ | アスタチン−２１１［Ａｔ−２１１］放射性医薬品の生産のための自動化プロセスプラットフォーム |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3979506A (en) * | 1974-10-11 | 1976-09-07 | Pierce Chemical Company | Radioactive compounds for labeling proteins |
| JPS5932457B2 (ja) * | 1978-11-29 | 1984-08-09 | エフ・ホフマン−ラ・ロシユ・ウント・コンパニ−・アクチエンゲゼルシヤフト | 放射性ヨウ素化アミン |
| DE2947500C2 (de) | 1979-11-24 | 1984-05-10 | Dutschka, Klaus, 4300 Essen | Radiojodierte ω -Phenylfettsäuren, ihre Herstellung und deren Verwendung zur szintigraphischen Untersuchung des Herzmuskels und der Leber |
-
1986
- 1986-05-16 DE DE8686303757T patent/DE3688103T2/de not_active Expired - Fee Related
- 1986-05-16 EP EP86303757A patent/EP0203764B1/en not_active Expired - Lifetime
- 1986-05-16 AT AT86303757T patent/ATE87290T1/de not_active IP Right Cessation
- 1986-05-16 NO NO861962A patent/NO861962L/no unknown
- 1986-05-16 DK DK226986A patent/DK226986A/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK226986D0 (da) | 1986-05-16 |
| ATE87290T1 (de) | 1993-04-15 |
| EP0203764A3 (en) | 1990-03-28 |
| DE3688103T2 (de) | 1993-07-15 |
| EP0203764A2 (en) | 1986-12-03 |
| EP0203764B1 (en) | 1993-03-24 |
| NO861962L (no) | 1986-11-18 |
| DE3688103D1 (de) | 1993-04-29 |
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