DE3688103D1 - Radiohalogenierte kleine molekuele fuer das markieren von proteinen. - Google Patents

Radiohalogenierte kleine molekuele fuer das markieren von proteinen.

Info

Publication number
DE3688103D1
DE3688103D1 DE8686303757T DE3688103T DE3688103D1 DE 3688103 D1 DE3688103 D1 DE 3688103D1 DE 8686303757 T DE8686303757 T DE 8686303757T DE 3688103 T DE3688103 T DE 3688103T DE 3688103 D1 DE3688103 D1 DE 3688103D1
Authority
DE
Germany
Prior art keywords
protein
compounds
metalated
functional group
radiohalogenated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686303757T
Other languages
English (en)
Other versions
DE3688103T2 (de
Inventor
Daniel Scott Wilbur
Alan Richard Fritzberg
David Schuster Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Poniard Pharmaceuticals Inc
Original Assignee
Poniard Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poniard Pharmaceuticals Inc filed Critical Poniard Pharmaceuticals Inc
Application granted granted Critical
Publication of DE3688103D1 publication Critical patent/DE3688103D1/de
Publication of DE3688103T2 publication Critical patent/DE3688103T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F3/00—Compounds containing elements of Groups 2 or 12 of the Periodic Table
    • C07F3/10—Mercury compounds
    • C07F3/12—Aromatic substances containing mercury
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE8686303757T 1985-05-17 1986-05-16 Radiohalogenierte kleine molekuele fuer das markieren von proteinen. Expired - Fee Related DE3688103T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73539285A 1985-05-17 1985-05-17
US85274086A 1986-04-21 1986-04-21

Publications (2)

Publication Number Publication Date
DE3688103D1 true DE3688103D1 (de) 1993-04-29
DE3688103T2 DE3688103T2 (de) 1993-07-15

Family

ID=27112875

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686303757T Expired - Fee Related DE3688103T2 (de) 1985-05-17 1986-05-16 Radiohalogenierte kleine molekuele fuer das markieren von proteinen.

Country Status (5)

Country Link
EP (1) EP0203764B1 (de)
AT (1) ATE87290T1 (de)
DE (1) DE3688103T2 (de)
DK (1) DK226986A (de)
NO (1) NO861962L (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4812577A (en) * 1987-04-28 1989-03-14 The United States Of America As Represented By The United States Department Of Energy Mercuric acetate phenyl maleimide useful for preparing radiohalogenated maleimides
US4977288A (en) * 1988-01-29 1990-12-11 President And Fellows Of Harvard College M-aminophenyltrialkylstannane
US5059541A (en) * 1988-04-29 1991-10-22 Neorx Corporation Minimal derivatization of proteins
US4966999A (en) * 1988-06-07 1990-10-30 Cytogen Corporation Radiohalogenated compounds for site specific labeling
US5066789A (en) * 1988-09-30 1991-11-19 Neorx Corporation Targeting substance-diagnostic/therapeutic agent conjugates having Schiff base linkages
JPH04504248A (ja) * 1988-09-30 1992-07-30 ネオロクス　コーポレーション シッフ塩基で結合した、ターゲティング物質―診断／治療薬複合体
US5102651A (en) * 1989-12-29 1992-04-07 Neorx Corporation Process for isolation and radiolabeling of pharmaceuticals with isotopes of astatine
US5463080A (en) * 1992-08-27 1995-10-31 Bracco International B.V. 2,4,6-triiodo-1,3-benzenedicarboxylic acid compounds used as radiolabelling reagents
GB0206750D0 (en) 2002-03-22 2002-05-01 Amersham Plc Radiofluorination methods
JP6830435B2 (ja) 2014-06-18 2021-02-17 リンデグレン、ストゥーレ アスタチン−２１１［Ａｔ−２１１］放射性医薬品の生産のための自動化プロセスプラットフォーム

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979506A (en) * 1974-10-11 1976-09-07 Pierce Chemical Company Radioactive compounds for labeling proteins
JPS5932457B2 (ja) * 1978-11-29 1984-08-09 エフ・ホフマン−ラ・ロシユ・ウント・コンパニ−・アクチエンゲゼルシヤフト 放射性ヨウ素化アミン
DE2947500C2 (de) 1979-11-24 1984-05-10 Dutschka, Klaus, 4300 Essen Radiojodierte ω -Phenylfettsäuren, ihre Herstellung und deren Verwendung zur szintigraphischen Untersuchung des Herzmuskels und der Leber

Also Published As

Publication number Publication date
DK226986A (da) 1986-11-18
DK226986D0 (da) 1986-05-16
ATE87290T1 (de) 1993-04-15
EP0203764A3 (en) 1990-03-28
DE3688103T2 (de) 1993-07-15
EP0203764A2 (de) 1986-12-03
EP0203764B1 (de) 1993-03-24
NO861962L (no) 1986-11-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee