ATE355259T1 - Radiofluorierungsverfahren - Google Patents

Radiofluorierungsverfahren

Info

Publication number
ATE355259T1
ATE355259T1 AT03710021T AT03710021T ATE355259T1 AT E355259 T1 ATE355259 T1 AT E355259T1 AT 03710021 T AT03710021 T AT 03710021T AT 03710021 T AT03710021 T AT 03710021T AT E355259 T1 ATE355259 T1 AT E355259T1
Authority
AT
Austria
Prior art keywords
sup
radiofluoration
compound
formula
radiopharmaceuticals
Prior art date
Application number
AT03710021T
Other languages
English (en)
Inventor
Alan Cuthbertson
Magne Solbakken
Joseph Maduabuchi Arukwe
Hege Karlsen
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Application granted granted Critical
Publication of ATE355259T1 publication Critical patent/ATE355259T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/008Peptides; Proteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03710021T 2002-03-22 2003-03-20 Radiofluorierungsverfahren ATE355259T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0206750.2A GB0206750D0 (en) 2002-03-22 2002-03-22 Radiofluorination methods

Publications (1)

Publication Number Publication Date
ATE355259T1 true ATE355259T1 (de) 2006-03-15

Family

ID=9933482

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03710021T ATE355259T1 (de) 2002-03-22 2003-03-20 Radiofluorierungsverfahren

Country Status (9)

Country Link
US (2) US7368474B2 (de)
EP (1) EP1487762B1 (de)
JP (1) JP4365223B2 (de)
AT (1) ATE355259T1 (de)
AU (1) AU2003214446A1 (de)
DE (1) DE60312136T2 (de)
ES (1) ES2282607T3 (de)
GB (1) GB0206750D0 (de)
WO (1) WO2003080544A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0305704D0 (en) * 2003-03-13 2003-04-16 Amersham Plc Radiofluorination methods
NO20033115D0 (no) * 2003-07-08 2003-07-08 Amersham Health As Peptid-baserte forbindelser
GB0329716D0 (en) * 2003-12-23 2004-01-28 Amersham Plc Radical trap
JP2007526300A (ja) 2004-03-04 2007-09-13 ジーイー・ヘルスケア・アクスイェ・セルスカプ 医薬化合物
CN102532264A (zh) * 2004-06-16 2012-07-04 通用电气医疗集团股份有限公司 基于肽的化合物
US20080095704A1 (en) * 2004-07-02 2008-04-24 Alan Cuthbertson Imaging Agents with Improved Pharmacokinetic Profiles
GB0420344D0 (en) 2004-09-14 2004-10-13 Amersham Plc Diagnostic compounds
CN101107016B (zh) 2004-11-22 2011-11-16 通用电气医疗集团股份有限公司 靶向细胞外基质的造影剂
GB0524987D0 (en) 2005-12-08 2006-01-18 Ge Healthcare Ltd Novel imaging agents for fibrosis
US8080815B2 (en) * 2006-05-26 2011-12-20 Abt Molecular Imaging, Inc. Biomarker generator
CA2662449A1 (en) 2006-09-08 2008-03-13 Bayer Schering Pharma Aktiengesellschaft Compounds and methods for 18f labeled agents
CA2664700A1 (en) * 2006-10-02 2008-04-10 Bayer Schering Pharma Aktiengesellschaft Silicon derivatives for pet imaging
EP2114464A2 (de) * 2006-12-28 2009-11-11 GE Healthcare AS Radiofluorinationsverfahren
CN101723847B (zh) * 2008-10-10 2013-01-16 北京师范大学 一类18f标记对硝基苯甲酰基氨基酸类化合物及其制备方法和应用
US8293208B2 (en) 2009-05-15 2012-10-23 The Governors Of The University Of Alberta Fluorinated fructose derivatives for PET imaging
US8273300B2 (en) * 2009-07-09 2012-09-25 Siemens Medical Solutions Usa, Inc. Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure
US8435454B2 (en) * 2009-07-09 2013-05-07 Siemens Medical Solutions Usa, Inc. Modular system for radiosynthesis with multi-run capabilities and reduced risk of radiation exposure
KR101229929B1 (ko) 2010-05-28 2013-02-05 서강대학교산학협력단 1,2,3-트리아졸기를 갖는 새로운 말레이미드 화합물, 이의 제조방법 및 이를 보결그룹으로 하는 생체화합물의 f­18 표지방법
WO2012033374A2 (ko) * 2010-09-09 2012-03-15 서강대학교 산학협력단 1,2,3-트리아졸륨 염을 갖는 설포네이트 전구체, 그 제조방법 및 이를 사용하는 분자내 친핵성 플루오르화반응
WO2013048832A1 (en) 2011-09-29 2013-04-04 Ge Healthcare Limited 18 f - labelled 6 - ( 2 - fluoroethoxy) - 2 - naphthaldehyde for detecting cancer stem cells
WO2013048811A1 (en) 2011-09-30 2013-04-04 Ge Healthcare Limited Imaging and radiotherapy methods for tumour stem cells

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3688103T2 (de) 1985-05-17 1993-07-15 Neorx Corp Radiohalogenierte kleine molekuele fuer das markieren von proteinen.
US4876081A (en) 1987-04-16 1989-10-24 Neorx Corporation Vinyl substituted radiohalogen and methods of use conjugates
US5144043A (en) * 1988-06-15 1992-09-01 Centocor Cleavable bifunctional coupling agents
US5144053A (en) * 1991-03-25 1992-09-01 Ethyl Corporation Aluminum alkyls and linear 1-olefins from internal olefins
DE19621177A1 (de) * 1996-05-24 1997-11-27 Basf Ag Kohlenhydratderivate und ihre Synthese an fester Phase
EP1009726B1 (de) * 1997-09-03 2007-02-14 Immunomedics, Inc. Fluorierung von proteinen und peptiden für positronemissionstomographie
US6350360B1 (en) 2000-04-07 2002-02-26 Sandia Coroporation Method of fabricating a 3-dimensional tool master
AU2002313616A1 (en) 2001-07-10 2003-01-29 Amersham Health As Peptide-based compounds for targeting intergin receptors
GB0317815D0 (en) * 2003-07-30 2003-09-03 Amersham Health As Imaging agents

Also Published As

Publication number Publication date
EP1487762B1 (de) 2007-02-28
US7368474B2 (en) 2008-05-06
JP2005520857A (ja) 2005-07-14
ES2282607T3 (es) 2007-10-16
AU2003214446A1 (en) 2003-10-08
GB0206750D0 (en) 2002-05-01
EP1487762A1 (de) 2004-12-22
WO2003080544A1 (en) 2003-10-02
US20080274052A1 (en) 2008-11-06
US20050142061A1 (en) 2005-06-30
JP4365223B2 (ja) 2009-11-18
DE60312136T2 (de) 2007-11-15
DE60312136D1 (de) 2007-04-12

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