JP2007512243A5 - - Google Patents
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- JP2007512243A5 JP2007512243A5 JP2006538514A JP2006538514A JP2007512243A5 JP 2007512243 A5 JP2007512243 A5 JP 2007512243A5 JP 2006538514 A JP2006538514 A JP 2006538514A JP 2006538514 A JP2006538514 A JP 2006538514A JP 2007512243 A5 JP2007512243 A5 JP 2007512243A5
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51733703P | 2003-11-04 | 2003-11-04 | |
| US60/517,337 | 2003-11-04 | ||
| US52557903P | 2003-11-26 | 2003-11-26 | |
| US60/525,579 | 2003-11-26 | ||
| US56571004P | 2004-04-27 | 2004-04-27 | |
| US60/565,710 | 2004-04-27 | ||
| PCT/US2004/036958 WO2005044294A2 (en) | 2003-11-04 | 2004-11-04 | Method of therapy for cancers expressing the cd40 antigen |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011033969A Division JP2011126900A (ja) | 2003-11-04 | 2011-02-18 | Ｃｄ４０抗原を発現する癌に対する治療方法。 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007512243A JP2007512243A (ja) | 2007-05-17 |
| JP2007512243A5 true JP2007512243A5 (https=) | 2007-12-13 |
| JP4765039B2 JP4765039B2 (ja) | 2011-09-07 |
Family
ID=34577667
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006538514A Expired - Fee Related JP4765039B2 (ja) | 2003-11-04 | 2004-11-04 | Ｃｄ４０抗原を発現する癌に対する治療方法。 |
| JP2006538513A Expired - Lifetime JP4746552B2 (ja) | 2003-11-04 | 2004-11-04 | 自己免疫疾患および炎症性疾患ならびに臓器移植拒絶の処置のためのアンタゴニスト抗ｃｄ４０抗体の使用 |
| JP2006538540A Expired - Lifetime JP5019881B2 (ja) | 2003-11-04 | 2004-11-04 | アンタゴニスト抗ｃｄ４０モノクローナル抗体およびそれらを使用するための方法 |
| JP2010277537A Withdrawn JP2011072317A (ja) | 2003-11-04 | 2010-12-13 | アンタゴニスト抗ｃｄ４０モノクローナル抗体およびそれらを使用するための方法 |
| JP2011033969A Withdrawn JP2011126900A (ja) | 2003-11-04 | 2011-02-18 | Ｃｄ４０抗原を発現する癌に対する治療方法。 |
| JP2011040922A Withdrawn JP2011105769A (ja) | 2003-11-04 | 2011-02-25 | 自己免疫疾患および炎症性疾患ならびに臓器移植拒絶の処置のためのアンタゴニスト抗ｃｄ４０抗体の使用 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006538513A Expired - Lifetime JP4746552B2 (ja) | 2003-11-04 | 2004-11-04 | 自己免疫疾患および炎症性疾患ならびに臓器移植拒絶の処置のためのアンタゴニスト抗ｃｄ４０抗体の使用 |
| JP2006538540A Expired - Lifetime JP5019881B2 (ja) | 2003-11-04 | 2004-11-04 | アンタゴニスト抗ｃｄ４０モノクローナル抗体およびそれらを使用するための方法 |
| JP2010277537A Withdrawn JP2011072317A (ja) | 2003-11-04 | 2010-12-13 | アンタゴニスト抗ｃｄ４０モノクローナル抗体およびそれらを使用するための方法 |
| JP2011033969A Withdrawn JP2011126900A (ja) | 2003-11-04 | 2011-02-18 | Ｃｄ４０抗原を発現する癌に対する治療方法。 |
| JP2011040922A Withdrawn JP2011105769A (ja) | 2003-11-04 | 2011-02-25 | 自己免疫疾患および炎症性疾患ならびに臓器移植拒絶の処置のためのアンタゴニスト抗ｃｄ４０抗体の使用 |
Country Status (22)
| Country | Link |
|---|---|
| EP (6) | EP1682180B1 (https=) |
| JP (6) | JP4765039B2 (https=) |
| KR (2) | KR101125127B1 (https=) |
| CN (2) | CN1905897B (https=) |
| AT (3) | ATE447412T1 (https=) |
| AU (3) | AU2004287879C1 (https=) |
| CA (3) | CA2544948A1 (https=) |
| CY (3) | CY1110231T1 (https=) |
| DE (3) | DE602004028505D1 (https=) |
| DK (4) | DK1682178T3 (https=) |
| EC (2) | ECSP066607A (https=) |
| ES (3) | ES2435410T3 (https=) |
| HR (2) | HRP20100066T1 (https=) |
| IL (1) | IL175225A (https=) |
| MA (1) | MA28331A1 (https=) |
| PL (4) | PL1682178T3 (https=) |
| PT (4) | PT1694360E (https=) |
| RS (2) | RS53073B (https=) |
| SG (1) | SG148143A1 (https=) |
| SI (3) | SI1682180T1 (https=) |
| WO (3) | WO2005044306A2 (https=) |
| ZA (1) | ZA200604419B (https=) |
Families Citing this family (86)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7658924B2 (en) | 2001-10-11 | 2010-02-09 | Amgen Inc. | Angiopoietin-2 specific binding agents |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| PT1694360E (pt) * | 2003-11-04 | 2010-12-13 | Novartis Vaccines & Diagnostic | Utilização de anticorpos monoclonais antagonistas anti-cd40 para o tratamento de doenças auto-imunes e inflamatórias e da rejeição ao transplante de orgãos |
| US8277810B2 (en) | 2003-11-04 | 2012-10-02 | Novartis Vaccines & Diagnostics, Inc. | Antagonist anti-CD40 antibodies |
| EP1844815B1 (en) * | 2003-11-04 | 2011-09-14 | Novartis Vaccines and Diagnostics, Inc. | Combination therapy comprising anti-CD20 and anti-CD40 antibodies for the treatment of B cell-related cancers |
| US20050281815A1 (en) * | 2004-02-26 | 2005-12-22 | Dani Eshel | CD40 splice variants and their uses |
| WO2006125117A2 (en) * | 2005-05-18 | 2006-11-23 | Novartis Ag | Methods for diagnosis and treatment of diseases having an autoimmune and/or inflammatory component |
| WO2006125143A2 (en) * | 2005-05-18 | 2006-11-23 | Novartis Ag | Methods for diagnosis and treatment of proliferative disorders mediated by cd40 signaling |
| MX2007015476A (es) | 2005-06-14 | 2008-02-25 | Amgen Inc | Formulaciones de proteina autoamortiguadoras. |
| JP2009513712A (ja) * | 2005-11-01 | 2009-04-02 | ノバルティス アーゲー | 抗ｃｄ４０抗体の使用 |
| US8926979B2 (en) | 2005-11-01 | 2015-01-06 | Novartis Ag | Treatment of cancer or pre-malignant conditions using anti-CD40 antibodies |
| PL2289909T3 (pl) | 2005-11-30 | 2015-04-30 | Abbvie Inc | Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał |
| RU2432362C2 (ru) | 2005-11-30 | 2011-10-27 | Эбботт Лэборетриз | Моноклональные антитела и их применения |
| EP1974017B2 (en) | 2005-12-09 | 2023-06-21 | Academisch Medisch Centrum bij de Universiteit van Amsterdam | Means and methods for influencing the stability of antibody producing cells |
| WO2007067032A1 (en) | 2005-12-09 | 2007-06-14 | Academisch Medisch Cemtrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of cells |
| AR059066A1 (es) | 2006-01-27 | 2008-03-12 | Amgen Inc | Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf) |
| MX2008013508A (es) * | 2006-04-21 | 2008-10-31 | Novartis Ag | Composiciones farmaceuticas de anticuerpos antagonistas anti-cd40. |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| JP5577098B2 (ja) * | 2006-12-21 | 2014-08-20 | アムジエン・インコーポレーテツド | ポリペプチドを含有する安定な緩衝化された製剤 |
| EP2124952A2 (en) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
| EP2170268A2 (en) | 2007-06-25 | 2010-04-07 | Amgen, Inc. | Compositions of specific binding agents to hepatocyte growth factor |
| MX2010005080A (es) | 2007-11-07 | 2010-07-28 | Genentech Inc | Metodos y composiciones para determinar la sensibilidad de linfoma de celula b al tratamiento con anticuerpos anti-cd40. |
| MX2010005099A (es) * | 2007-11-09 | 2010-05-27 | Novartis Ag | Usos de anticuerpos anti-cd40. |
| JO2913B1 (en) | 2008-02-20 | 2015-09-15 | امجين إنك, | Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses |
| KR101787768B1 (ko) | 2009-04-18 | 2017-10-18 | 제넨테크, 인크. | 항-ｃｄ４０ 항체를 사용한 치료에 대한 ｂ-세포 림프종의 반응성 평가를 위한 방법 |
| JP5781508B2 (ja) | 2009-07-15 | 2015-09-24 | アイム・セラピューティクス・べー・フェー | 高親和性抗体を産生させるための手段および方法 |
| ES2684475T3 (es) | 2010-04-15 | 2018-10-03 | Abbvie Inc. | Proteínas que se unen a beta amiloide |
| CN103298833B (zh) | 2010-08-14 | 2015-12-16 | Abbvie公司 | β淀粉样蛋白结合蛋白 |
| PE20141162A1 (es) | 2010-11-04 | 2014-09-18 | Boehringer Ingelheim Int | Anticuerpos anti-il-23 |
| AR083847A1 (es) * | 2010-11-15 | 2013-03-27 | Novartis Ag | Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40 |
| AU2016201742B2 (en) * | 2010-11-15 | 2017-11-02 | Novartis Ag | Silent Fc variants of anti-CD40 antibodies |
| WO2012075111A1 (en) | 2010-11-30 | 2012-06-07 | Novartis Ag | Uses of anti-cd40 antibodies in combination therapy for b cell-related cancers |
| EP2646466B1 (en) * | 2010-12-02 | 2017-03-29 | AIMM Therapeutics B.V. | Means and methods for producing high affinity antibodies |
| JP5458188B2 (ja) * | 2011-02-17 | 2014-04-02 | 協和発酵キリン株式会社 | 抗ｃｄ４０抗体の高濃度製剤 |
| ES2653639T3 (es) * | 2011-02-28 | 2018-02-08 | Napajen Pharma, Inc. | Complejo ácido nucleico-polisacárido |
| HUE065915T2 (hu) | 2011-03-11 | 2024-06-28 | Beth Israel Deaconess Medical Ct Inc | Anti-CD40 antitestek és alkalmazásaik |
| BR112013026828A2 (pt) * | 2011-04-21 | 2016-11-29 | Bristol Myers Squibb Co | polipeptídeos de anticorpo que antagonizam cd40 |
| SG10201604104PA (en) | 2011-10-25 | 2016-07-28 | Prothena Therapeutics Ltd | Antibody formulations and methods |
| KR102057742B1 (ko) | 2011-11-17 | 2019-12-19 | 군드람 정 | 의학적 용도를 위한 이중특이성 항체 |
| EP4039275A1 (en) * | 2012-05-03 | 2022-08-10 | Boehringer Ingelheim International GmbH | Anti-il-23p19 antibodies |
| US20140004131A1 (en) | 2012-05-04 | 2014-01-02 | Novartis Ag | Antibody formulation |
| AU2013337903B2 (en) * | 2012-10-30 | 2018-08-16 | Apexigen, Inc. | Anti-CD40 antibodies and methods of use |
| ES2649991T3 (es) | 2012-11-19 | 2018-01-16 | Baliopharm Ag | Anticuerpo biespecífico recombinante que se une a CD20 y CD95 |
| WO2014200349A1 (en) * | 2013-06-13 | 2014-12-18 | Fast Forward Pharmaceutical B.V. | Cd40 signalling inhibitor and a further compound, wherein the further compound is a bile acid, a bile acid derivative, an tgr5-receptor agonist, an fxr agonist or a combination thereof, for the treatment of chronic inflammation, and the prevention of gastrointestinal cancer or fibrosis. |
| AU2015211480B2 (en) | 2014-01-31 | 2020-05-14 | Kling Biotherapeutics B.V. | Means and methods for producing stable antibodies |
| WO2015134988A1 (en) | 2014-03-07 | 2015-09-11 | Bristol-Myers Squibb Company | Method of using antibody polypeptides that antagonize cd40 to treat ibd |
| US10618963B2 (en) | 2014-03-12 | 2020-04-14 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| AU2015228372B2 (en) | 2014-03-12 | 2018-05-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| CN108025068A (zh) * | 2014-03-12 | 2018-05-11 | 耶达研究与开发有限公司 | 降低系统性调节性t细胞水平或活性来治疗cns的疾病和损伤 |
| EA201691634A1 (ru) * | 2014-03-19 | 2016-11-30 | Бристол-Маерс Сквибб Компани | Способы лечения отторжения трансплантата с использованием доменного антитела, направленного против cd40l |
| EP3172339A1 (en) | 2014-07-24 | 2017-05-31 | Boehringer Ingelheim International GmbH | Biomarkers useful in the treatment of il-23a related diseases |
| WO2016029043A1 (en) | 2014-08-21 | 2016-02-25 | The General Hospital Corporation | Tumor necrosis factor superfamily and tnf-like ligand muteins and methods of preparing and using the same |
| UA123624C2 (uk) | 2014-09-03 | 2021-05-05 | Бьорінґер Інґельхайм Інтернаціональ Ґмбх | Сполука, специфічна до іл-23а та фнп-альфа, та її застосування |
| AU2015360502A1 (en) | 2014-12-10 | 2017-06-29 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| CN107206081A (zh) | 2015-02-04 | 2017-09-26 | 勃林格殷格翰国际有限公司 | 治疗炎性疾病的方法 |
| US10174121B2 (en) | 2015-05-29 | 2019-01-08 | Abbvie, Inc. | Anti-CD40 antibodies |
| LT4209499T (lt) | 2015-08-13 | 2024-11-25 | Amgen Inc. | Antigeną surišančių baltymų įkrautas giluminis filtravimas |
| WO2017040932A1 (en) | 2015-09-04 | 2017-03-09 | Primatope Therapeutics Inc. | Humanized anti-cd40 antibodies and uses thereof |
| CR20180177A (es) * | 2015-09-30 | 2018-06-22 | Janssen Biotech Inc | Anticuerpos agonistas que se unen específicamente a cd40 humana y método de uso |
| US12297266B2 (en) | 2016-04-18 | 2025-05-13 | Celldex Therapeutics, Inc. | Agonistic antibodies that bind human CD40 and uses thereof |
| KR102379464B1 (ko) | 2016-06-20 | 2022-03-29 | 키맵 리미티드 | 항-pd-l1 항체 |
| SG11201811431VA (en) | 2016-07-14 | 2019-01-30 | Genmab As | Multispecific antibodies against cd40 and cd137 |
| MX2019014375A (es) * | 2017-06-01 | 2020-01-23 | Jiangsu Hengrui Medicine Co | Anticuerpo anti-cd40, fragmento de union a antigeno del mismo, y uso medico del mismo. |
| WO2018222019A1 (ko) * | 2017-06-01 | 2018-12-06 | 서울대학교 산학협력단 | 신규한 항-ｃｄ40 항체 및 이의 용도 |
| SG11202000198QA (en) | 2017-08-04 | 2020-02-27 | Genmab As | Binding agents binding to pd-l1 and cd137 and use thereof |
| HRP20240485T1 (hr) | 2017-08-24 | 2024-07-05 | Novo Nordisk A/S | Pripravci glp-1 i njihova upotreba |
| EP3746478A4 (en) * | 2018-01-29 | 2022-01-19 | The Regents of The University of California | THERAPIES AND METHODS OF TREATING TLR2-MEDIATED DISEASES AND DISORDERS |
| CA3090322A1 (en) * | 2018-02-12 | 2019-08-15 | Diabetes-Free, Inc. | Improved antagonistic anti-human cd40 monoclonal antibodies |
| CN112638375A (zh) | 2018-06-15 | 2021-04-09 | 旗舰创业创新五公司 | 通过后细胞信号传导因子的调节来增加免疫活性 |
| WO2020102454A1 (en) | 2018-11-13 | 2020-05-22 | Regents Of The University Of Minnesota | Cd40 targeted peptides and uses thereof |
| AR117091A1 (es) * | 2018-11-19 | 2021-07-07 | Bristol Myers Squibb Co | Anticuerpos monoclonales antagonistas contra cd40 y sus usos |
| WO2020227159A2 (en) | 2019-05-03 | 2020-11-12 | Flagship Pioneering Innovations V, Inc. | Methods of modulating immune activity |
| US12577297B2 (en) | 2019-09-09 | 2026-03-17 | Boehringer Ingelheim International Gmbh | Anti-IL-23p19 antibody formulations |
| JP2023509359A (ja) | 2019-12-17 | 2023-03-08 | フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド | 鉄依存性細胞分解の誘導物質との併用抗癌療法 |
| PE20230819A1 (es) | 2020-02-18 | 2023-05-19 | Novo Nordisk As | Composiciones y usos de glp-1 |
| JP2023532339A (ja) | 2020-06-29 | 2023-07-27 | フラグシップ パイオニアリング イノベーションズ ブイ，インコーポレーテッド | サノトランスミッションを促進するためにエンジニアリングされたウイルス及び癌の処置におけるそれらの使用 |
| CN111763259B (zh) * | 2020-09-03 | 2020-12-15 | 北京百奥赛图基因生物技术有限公司 | 抗cd40抗体及其用途 |
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