DK1682178T3 - Fremgangsmåder til terapi af cancere der udtrykker CD-40-antigenet - Google Patents

Fremgangsmåder til terapi af cancere der udtrykker CD-40-antigenet

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Publication number
DK1682178T3
DK1682178T3 DK04810421.0T DK04810421T DK1682178T3 DK 1682178 T3 DK1682178 T3 DK 1682178T3 DK 04810421 T DK04810421 T DK 04810421T DK 1682178 T3 DK1682178 T3 DK 1682178T3
Authority
DK
Denmark
Prior art keywords
methods
antigen
dosing regimen
antibody
treating
Prior art date
Application number
DK04810421.0T
Other languages
English (en)
Inventor
Li Long
Mohammad Luqman
Asha Yabannavar
Isabel Zaror
Deborah Hurst
De Menezes Daniel E Lopes
Original Assignee
Novartis Vaccines & Diagnostic
Xoma Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34577667&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1682178(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Vaccines & Diagnostic, Xoma Technology Ltd filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of DK1682178T3 publication Critical patent/DK1682178T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
DK04810421.0T 2003-11-04 2004-11-04 Fremgangsmåder til terapi af cancere der udtrykker CD-40-antigenet DK1682178T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US51733703P 2003-11-04 2003-11-04
US52557903P 2003-11-26 2003-11-26
US56571004P 2004-04-27 2004-04-27
PCT/US2004/036958 WO2005044294A2 (en) 2003-11-04 2004-11-04 Method of therapy for cancers expressing the cd40 antigen

Publications (1)

Publication Number Publication Date
DK1682178T3 true DK1682178T3 (da) 2010-10-04

Family

ID=34577667

Family Applications (4)

Application Number Title Priority Date Filing Date
DK04810421.0T DK1682178T3 (da) 2003-11-04 2004-11-04 Fremgangsmåder til terapi af cancere der udtrykker CD-40-antigenet
DK04810420.2T DK1694360T3 (da) 2003-11-04 2004-11-04 Anvendelse af antagonist anti-CD40-antistoffer til behandling af autoimmune og inflammatoriske sygdomme og organtransplantationafstødning
DK04810510T DK1682180T3 (da) 2003-11-04 2004-11-04 Monoklonale antagonist-anti-CD40-antistoffer og fremgangsmåder til anvendelse deraf
DK09075395.5T DK2149585T3 (da) 2003-11-04 2004-11-04 Anvendelse af antagonistiske anti-CD40-monoklonale antistoffer

Family Applications After (3)

Application Number Title Priority Date Filing Date
DK04810420.2T DK1694360T3 (da) 2003-11-04 2004-11-04 Anvendelse af antagonist anti-CD40-antistoffer til behandling af autoimmune og inflammatoriske sygdomme og organtransplantationafstødning
DK04810510T DK1682180T3 (da) 2003-11-04 2004-11-04 Monoklonale antagonist-anti-CD40-antistoffer og fremgangsmåder til anvendelse deraf
DK09075395.5T DK2149585T3 (da) 2003-11-04 2004-11-04 Anvendelse af antagonistiske anti-CD40-monoklonale antistoffer

Country Status (23)

Country Link
EP (6) EP2149585B1 (da)
JP (6) JP4765039B2 (da)
KR (2) KR101125127B1 (da)
CN (2) CN1905897B (da)
AT (3) ATE473016T1 (da)
AU (3) AU2004287482B2 (da)
CA (3) CA2544949C (da)
CY (3) CY1110231T1 (da)
DE (3) DE602004028505D1 (da)
DK (4) DK1682178T3 (da)
EC (2) ECSP066607A (da)
ES (3) ES2346977T3 (da)
HK (4) HK1095270A1 (da)
HR (2) HRP20100066T1 (da)
IL (1) IL175225A (da)
MA (1) MA28331A1 (da)
PL (4) PL2149585T3 (da)
PT (4) PT1682180E (da)
RS (2) RS53073B (da)
SG (1) SG148143A1 (da)
SI (3) SI1682178T1 (da)
WO (3) WO2005044854A2 (da)
ZA (1) ZA200604419B (da)

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ATE516819T1 (de) * 2003-11-04 2011-08-15 Novartis Vaccines & Diagnostic Verfahren zur behandlung von b-zell-bedingtem krebs
PL2149585T3 (pl) * 2003-11-04 2014-01-31 Novartis Vaccines & Diagnostics Inc Zastosowanie antagonistycznych przeciwciał monoklonalnych anty-CD40
US8277810B2 (en) 2003-11-04 2012-10-02 Novartis Vaccines & Diagnostics, Inc. Antagonist anti-CD40 antibodies
US20050281815A1 (en) * 2004-02-26 2005-12-22 Dani Eshel CD40 splice variants and their uses
EP1894012A2 (en) * 2005-05-18 2008-03-05 Novartis AG Methods for diagnosis and treatment of proliferative disorders mediated by cd40 signaling
PT1889065E (pt) 2005-05-18 2013-09-27 Novartis Ag Métodos para o diagnóstico e tratamento de doenças tendo uma componente autoimune e/ou inflamatória
JP2008543839A (ja) 2005-06-14 2008-12-04 アムジェン インコーポレーテッド 自己緩衝タンパク質製剤
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US8691224B2 (en) 2005-11-30 2014-04-08 Abbvie Inc. Anti-Aβ globulomer 5F7 antibodies
KR20180058863A (ko) 2005-11-30 2018-06-01 애브비 인코포레이티드 아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도
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BRPI0820707A2 (pt) * 2007-11-07 2015-06-16 Genentech Inc Métodos e composição para avaliar a responsividade do linfoma de células b para o tratamento com anticorpos anti-cd40
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DK2454283T3 (da) 2009-07-15 2018-05-07 Aimm Therapeutics Bv Midler og fremgangsmåder til fremstilling af antistoffer med høj affinitet
US8987419B2 (en) 2010-04-15 2015-03-24 AbbVie Deutschland GmbH & Co. KG Amyloid-beta binding proteins
CN103298833B (zh) 2010-08-14 2015-12-16 Abbvie公司 β淀粉样蛋白结合蛋白
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AU2004287879B2 (en) 2011-01-06

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