IL144952A0 - Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof - Google Patents

Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof

Info

Publication number
IL144952A0
IL144952A0 IL14495200A IL14495200A IL144952A0 IL 144952 A0 IL144952 A0 IL 144952A0 IL 14495200 A IL14495200 A IL 14495200A IL 14495200 A IL14495200 A IL 14495200A IL 144952 A0 IL144952 A0 IL 144952A0
Authority
IL
Israel
Prior art keywords
production
methods
nucleic acids
acids encoding
chimeric polypeptides
Prior art date
Application number
IL14495200A
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP99107611A external-priority patent/EP1067194A1/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL144952A0 publication Critical patent/IL144952A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
IL14495200A 1999-04-16 2000-04-13 Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof IL144952A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99107611A EP1067194A1 (en) 1999-04-16 1999-04-16 Vectors containing a gene coding for CD40 and/or CD40L under the control of a cytokine-inducible promoter which is a human acute phase amyloid A gene promoter. Methods for their production and uses thereof
EP99113967 1999-07-17
PCT/EP2000/003318 WO2000063395A1 (en) 1999-04-16 2000-04-13 Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof

Publications (1)

Publication Number Publication Date
IL144952A0 true IL144952A0 (en) 2002-06-30

Family

ID=26152970

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14495200A IL144952A0 (en) 1999-04-16 2000-04-13 Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof

Country Status (8)

Country Link
EP (1) EP1173589A1 (en)
JP (1) JP2003508016A (en)
AR (1) AR023482A1 (en)
AU (1) AU3966200A (en)
CA (1) CA2369820A1 (en)
IL (1) IL144952A0 (en)
NO (1) NO20015003D0 (en)
WO (1) WO2000063395A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002028481A2 (en) 2000-10-02 2002-04-11 Chiron Corporation Methods of therapy for b-cell malignancies using antagonist anti-cd40 antibodies
AU2002221780A1 (en) * 2000-10-31 2002-05-15 F.Hoffmann-La Roche Ag Nucleic acids encoding cd40/cd40l chimeric polypeptides, methods for their production and uses thereof
DK1682177T3 (en) 2003-11-04 2010-11-01 Novartis Vaccines & Diagnostic Use of antagonist anti-CD40 antibodies to treat chronic lymphocytic leukemia
DE602004028643D1 (en) 2003-11-04 2010-09-23 Novartis Vaccines & Diagnostic METHOD FOR TREATING SOLID TUMORS EXPRESSING CD40 CELL SURFACE ANTIGEN
ES2346977T3 (en) 2003-11-04 2010-10-22 Novartis Vaccines And Diagnostics, Inc. THERAPY PROCEDURE FOR CANCERES THAT EXPRESS THE ANTIGEN CD40.
US20070098718A1 (en) 2003-11-04 2007-05-03 Chiron Methods of therapy for b cell-related cancers
DE602004028272D1 (en) 2003-11-04 2010-09-02 Novartis Vaccines & Diagnostic USE OF ANTAGONIST ANTI-CD40 MONOCLONAL ANTIBODIES FOR THE TREATMENT OF MULTIPLE MYELOMA
US8333970B2 (en) 2005-05-18 2012-12-18 Novartis Ag Methods of monitoring the efficacy of anti-CD40 antibodies in treating a subject having an inflammatory or autoimmune disease
UA94264C2 (en) 2006-04-21 2011-04-26 Новартис Аг Stable liquid antagonist anti-cd40 antibody-containing pharmaceutical composition
PL2066339T3 (en) 2006-09-18 2015-02-27 Univ Arkansas Compositions and methods of enhancing immune responses
NZ585776A (en) 2007-10-30 2012-07-27 Univ Arkansas Compositions and methods of enhancing immune responses to flagellated bacterium
NZ585777A (en) 2007-11-01 2012-09-28 Univ Arkansas Compositions and methods of enhancing immune responses to eimeria
JP5568807B2 (en) * 2008-06-06 2014-08-13 静岡県 Identification of melanoma markers using proteomic analysis
MX341775B (en) 2010-01-21 2016-09-02 The Texas A&M Univ System * Vaccine vectors and methods of enhancing immune responses.
PT2579901T (en) 2010-06-09 2019-11-05 Univ Arkansas Vaccine and methods to reduce campylobacter infection
WO2012075111A1 (en) 2010-11-30 2012-06-07 Novartis Ag Uses of anti-cd40 antibodies in combination therapy for b cell-related cancers
PT2956165T (en) 2013-02-14 2019-11-29 Texas A & M Univ Sys Compositions and methods of enhancing immune responses to eimeria or limiting eimeria infection
CN105142653B (en) 2013-03-15 2019-11-15 阿肯色大学评议会 Enhance the composition and method to enteropathogen immune response
TWI758288B (en) 2016-05-03 2022-03-21 阿肯色州大學董事會 Yeast vaccine vector including immunostimulatory and antigenic polypeptides and methods of using the same
EP3541931A4 (en) * 2016-11-21 2020-11-04 Nant Holdings IP, LLC Fractal combination therapy
EP3807307A1 (en) * 2018-06-14 2021-04-21 NantBio, Inc. Tnf-type receptor-ligand fusion proteins and methods
CN113056479A (en) * 2018-10-05 2021-06-29 南特细胞公司 CD40 and CD40L conjugates in an adenoviral vaccine vehicle

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2312667C (en) * 1991-10-25 2002-11-19 Immunex Corporation Novel cytokine
US5716805A (en) * 1991-10-25 1998-02-10 Immunex Corporation Methods of preparing soluble, oligomeric proteins
US7070771B1 (en) * 1996-12-09 2006-07-04 Regents Of The University Of California Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells

Also Published As

Publication number Publication date
WO2000063395A1 (en) 2000-10-26
JP2003508016A (en) 2003-03-04
AR023482A1 (en) 2002-09-04
NO20015003L (en) 2001-10-15
AU3966200A (en) 2000-11-02
EP1173589A1 (en) 2002-01-23
NO20015003D0 (en) 2001-10-15
CA2369820A1 (en) 2000-10-26

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