IN2004DE03129A - Phytases, nucleic acids encoding them and methods for making and using them - Google Patents

Phytases, nucleic acids encoding them and methods for making and using them

Info

Publication number
IN2004DE03129A
IN2004DE03129A IN3129DE2004A IN2004DE03129A IN 2004DE03129 A IN2004DE03129 A IN 2004DE03129A IN 3129DE2004 A IN3129DE2004 A IN 3129DE2004A IN 2004DE03129 A IN2004DE03129 A IN 2004DE03129A
Authority
IN
India
Prior art keywords
phytases
making
methods
nucleic acids
acids encoding
Prior art date
Application number
Inventor
Jay M Short
Keith Kretz
Kevin A Gray
Nelson R Barton
James B Garrett
Eileen O'donoghue
Eric J Mathur
Original Assignee
Diversa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diversa Corp filed Critical Diversa Corp
Publication of IN2004DE03129A publication Critical patent/IN2004DE03129A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • AHUMAN NECESSITIES
    • A21BAKING; EDIBLE DOUGHS
    • A21DTREATMENT, e.g. PRESERVATION, OF FLOUR OR DOUGH, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS; PRESERVATION THEREOF
    • A21D8/00Methods for preparing or baking dough
    • A21D8/02Methods for preparing dough; Treating dough prior to baking
    • A21D8/04Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes
    • A21D8/042Methods for preparing dough; Treating dough prior to baking treating dough with microorganisms or enzymes with enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23JPROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00Working-up of proteins for foodstuffs
    • A23J3/14Vegetable proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/30Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L11/00Pulses, i.e. fruits of leguminous plants, for production of food; Products from legumes; Preparation or treatment thereof
    • A23L11/30Removing undesirable substances, e.g. bitter substances
    • A23L11/33Removing undesirable substances, e.g. bitter substances using enzymes; Enzymatic transformation of pulses or legumes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20Removal of unwanted matter, e.g. deodorisation or detoxification
    • A23L5/25Removal of unwanted matter, e.g. deodorisation or detoxification using enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L7/00Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10Cereal-derived products
    • A23L7/104Fermentation of farinaceous cereal or cereal material; Addition of enzymes or microorganisms
    • A23L7/107Addition or treatment with enzymes not combined with fermentation with microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/030083-Phytase (3.1.3.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/03Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/030264-Phytase (3.1.3.26), i.e. 6-phytase
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Animal Husbandry (AREA)
  • Botany (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physiology (AREA)
  • Agronomy & Crop Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
IN3129DE2004 2001-05-24 2004-10-12 Phytases, nucleic acids encoding them and methods for making and using them IN2004DE03129A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/866,379 US6855365B2 (en) 1997-08-13 2001-05-24 Recombinant bacterial phytases and uses thereof

Publications (1)

Publication Number Publication Date
IN2004DE03129A true IN2004DE03129A (en) 2005-04-01

Family

ID=25347484

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3129DE2004 IN2004DE03129A (en) 2001-05-24 2004-10-12 Phytases, nucleic acids encoding them and methods for making and using them

Country Status (9)

Country Link
US (1) US6855365B2 (en)
EP (1) EP1478769A4 (en)
JP (1) JP2005505254A (en)
KR (1) KR20040099097A (en)
CN (1) CN1592791B (en)
BR (2) BRPI0208851B1 (en)
CA (1) CA2441666A1 (en)
IN (1) IN2004DE03129A (en)
WO (1) WO2002095003A2 (en)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7432097B2 (en) * 1997-08-13 2008-10-07 Verenium Corporation Phytases, nucleic acids encoding them and methods of making and using them
US6720014B1 (en) * 1997-08-13 2004-04-13 Diversa Corporation Phytase-containing foodstuffs and methods of making and using them
US7078035B2 (en) * 1997-08-13 2006-07-18 Diversa Corporation Phytases, nucleic acids encoding them and methods for making and using them
US6183740B1 (en) * 1997-08-13 2001-02-06 Diversa Corporation Recombinant bacterial phytases and uses thereof
US6451572B1 (en) 1998-06-25 2002-09-17 Cornell Research Foundation, Inc. Overexpression of phytase genes in yeast systems
US6841370B1 (en) 1999-11-18 2005-01-11 Cornell Research Foundation, Inc. Site-directed mutagenesis of Escherichia coli phytase
TWI332822B (en) 2001-10-31 2010-11-11 Phytex Llc Phytase-containing animal food and method
TW200305430A (en) * 2001-12-28 2003-11-01 Syngenta Participations Ag Thermotolerant phytase for animal feed
TWI262083B (en) * 2001-12-28 2006-09-21 Syngenta Participations Ag Microbially-expressed thermotolerant phytase for animal feed
CN101792749B (en) * 2002-08-12 2012-09-05 金克克国际有限公司 Mutant colibacillus appa phytase enzymes
AU2003272410A1 (en) 2002-09-13 2004-04-30 Cornell Research Foundation, Inc. Using mutations to improve aspergillus phytases
CA2413240A1 (en) * 2002-11-29 2004-05-29 Mcn Bioproducts Inc. Purification of inositol from plant materials
US7442398B2 (en) * 2003-03-25 2008-10-28 Republic Of National Fisheries Research And Development Institute Phytase produced from Citrobacter braakii
CA2531501A1 (en) * 2003-07-07 2005-02-17 Syngenta Participations Ag Reagents, methods and kits for detecting feed enzymes
US7374786B2 (en) 2004-01-09 2008-05-20 Biosys Corporation Bioimmune-aggressin composition for suppression of xanthomonad infections in agriculture crops
US20060073193A1 (en) * 2004-09-27 2006-04-06 Novozymes A/S Enzyme granules
DE10180655T8 (en) 2004-09-27 2013-04-25 Novozymes A/S Phytase granules in animal nutrition
DE102004050410A1 (en) 2004-10-15 2006-06-08 Ab Enzymes Gmbh Polypeptide with phytase activity and this coding nucleotide sequence
CA2585098C (en) 2004-10-22 2018-12-18 Revivicor, Inc. Porcine genomic kappa and lambda light chain sequences
CA2641349A1 (en) * 2005-02-04 2006-08-10 University Of Aarhus A method for recycling important nutritional elements from waste
US7658922B2 (en) * 2005-06-24 2010-02-09 Ab Enzymes Gmbh Monoclonal antibodies, hybridoma cell lines, methods and kits for detecting phytase
GB0600913D0 (en) 2006-01-17 2006-02-22 Syngenta Ltd Improvements in or relating to organic compounds
WO2007084769A2 (en) 2006-01-19 2007-07-26 Solazyme, Inc. Microalgae-derived compositions for improving the health and appearance of skin
US7919297B2 (en) 2006-02-21 2011-04-05 Cornell Research Foundation, Inc. Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase
JP5340138B2 (en) * 2006-04-30 2013-11-13 フィード リサーチ インスティチュート チャイニーズ アカデミー オブ アグリカルチュアル サイエンシィズ Cloning and expression of a novel phytase
US8540984B2 (en) * 2006-08-03 2013-09-24 Cornell Research Foundation, Inc. Phytases with improved thermal stability
DK2617814T3 (en) * 2006-09-21 2016-02-22 Basf Enzymes Llc Phytases, nucleic acids encoding them, and methods of producing and using them
DE102006053059A1 (en) 2006-11-10 2008-05-15 Ab Enzymes Gmbh Polypeptide with phytase activity and increased temperature stability of the enzyme activity and this coding nucleotide sequence
EP2129781B1 (en) * 2007-03-26 2014-01-22 Novozymes A/S Hafnia phytase
US8192734B2 (en) 2007-07-09 2012-06-05 Cornell University Compositions and methods for bone strengthening
US8673609B2 (en) * 2008-04-18 2014-03-18 Danisco Us Inc. Buttiauxella sp. phytase variants
US8367392B2 (en) * 2008-09-05 2013-02-05 Transalgae Ltd. Genetic transformation of algal and cyanobacteria cells by microporation
WO2010027505A2 (en) * 2008-09-05 2010-03-11 Doron Eisenstadt Decreasing rubisco content of algae and cyanobacteria cultivated in high carbon dioxide
EP2348827B1 (en) 2008-10-27 2015-07-01 Revivicor, Inc. Immunocompromised ungulates
WO2010054513A1 (en) * 2008-11-14 2010-05-20 Fujian Fuda Biotech Co. Ltd. A thermotolerant non-k12 escherichia coli phytase and its production
NZ596459A (en) 2009-05-21 2013-11-29 Verenium Corp Phytases, nucleic acids encoding them and methods for making and using them
US20110081706A1 (en) * 2009-10-02 2011-04-07 TransAlgae Ltd Method and system for efficient harvesting of microalgae and cyanobacteria
CN102559632B (en) * 2010-12-22 2013-06-26 武汉新华扬生物股份有限公司 Optimized and improved escherichia coli phytase APPA-M with enhanced catalytic activity in acidic range, and gene and application of optimized and improved escherichia coli phytase APPA-M
CN102629304B (en) * 2012-04-05 2015-02-04 天津大学 Genome scale metabolic network model-based metabolic engineering design prediction method
GB201308828D0 (en) 2013-03-12 2013-07-03 Verenium Corp Phytase
GB201308843D0 (en) 2013-03-14 2013-07-03 Verenium Corp Phytase formulation
KR20160033711A (en) 2013-07-25 2016-03-28 바스프 엔자임스 엘엘씨 Phytase
WO2015197871A1 (en) 2014-06-27 2015-12-30 Dsm Ip Assets B.V. A method for improving the nutritional value of animal feed
BR112018067862A2 (en) * 2016-03-08 2019-04-16 Basf Enzymes Llc method to improve the efficiency of yeast ethanol production.
US10351832B2 (en) 2016-06-30 2019-07-16 Fornia Biosolutions, Inc. Phytases and uses thereof
US9528096B1 (en) * 2016-06-30 2016-12-27 Fornia Biosolutions, Inc. Phytases and uses thereof
US9605245B1 (en) 2016-06-30 2017-03-28 Fornia BioSoultions, Inc. Phytases and uses thereof
CN109536399B (en) * 2018-10-16 2021-05-14 北京泛球生物科技有限公司 High-throughput screening method for virginiamycin high-producing strains
WO2021239206A1 (en) 2020-05-25 2021-12-02 N.V. Nutricia Process for lowering phytic acid in cereals
CN112979356A (en) * 2021-05-24 2021-06-18 中国农业科学院农业环境与可持续发展研究所 Application of microbial gene abundance and extracellular enzyme activity in straw returning and carbon fixation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340522C (en) 1987-03-10 1999-05-04 Heinz Dobeli Fusion proteins containing neighbouring histidines for improved purification
US5593963A (en) 1990-09-21 1997-01-14 Mogen International Expression of phytase in plants
NZ330940A (en) 1997-07-24 2000-02-28 F Production of consensus phytases from fungal origin using computer programmes
US6183740B1 (en) * 1997-08-13 2001-02-06 Diversa Corporation Recombinant bacterial phytases and uses thereof
US6720014B1 (en) * 1997-08-13 2004-04-13 Diversa Corporation Phytase-containing foodstuffs and methods of making and using them
US5876997A (en) 1997-08-13 1999-03-02 Diversa Corporation Phytase
EP1170994A1 (en) * 1999-04-23 2002-01-16 University Of Guelph Transgenic animals expressing salivary proteins

Also Published As

Publication number Publication date
WO2002095003A2 (en) 2002-11-28
WO2002095003A3 (en) 2004-09-23
EP1478769A2 (en) 2004-11-24
CA2441666A1 (en) 2002-11-28
CN1592791A (en) 2005-03-09
KR20040099097A (en) 2004-11-26
US20020136754A1 (en) 2002-09-26
BR0208851A (en) 2006-02-07
CN1592791B (en) 2012-09-05
BR122014019327B1 (en) 2015-12-15
JP2005505254A (en) 2005-02-24
EP1478769A4 (en) 2006-07-19
BRPI0208851B1 (en) 2015-07-21
US6855365B2 (en) 2005-02-15

Similar Documents

Publication Publication Date Title
IN2004DE03129A (en) Phytases, nucleic acids encoding them and methods for making and using them
ZA200500171B (en) Xylanases, nucleic acids encoding them and methods for making and using them
PT1497418E (en) Phospholipases, nucleic acids encoding them and methods for making and using them
AU2002322091A1 (en) Cellulases, nucleic acids encoding them and methods for making and using them
AU2003225947A8 (en) Amylases, nucleic acids encoding them and methods for making and using them
EP1727898A4 (en) Amylases, nucleic acids encoding them and methods for making and using them
MX282672B (en) Proteases, nucleic acids encoding them and methods for making and using them.
PL1613733T3 (en) Pectate lyases, nucleic acids encoding them and methods for making and using them
EP1576108A4 (en) Nitrilases, nucleic acids encoding them and methods for making and using them
EP1578937A4 (en) Xylose isomerases, nucleic acids encoding them and methods for making and using them
AU2003285906A8 (en) Amylases, nucleic acids encoding them and methods for making and using them
AU2003252111A8 (en) Fluorescent proteins, nucleic acids encoding them and methods for making and using them
ZA200508046B (en) Amylases, nucleic acids encoding them and methods for making and using them
AU2002365909A8 (en) Glycosidases, nucleic acids encoding them and methods of making and using them
AU2002365905A8 (en) Transaminases, nucleic acids encoding them and methods of making and using them
EP1383533A4 (en) Proteins and nucleic acids encoding same
AU2002339862A8 (en) Abrogen polypeptides, nucleic acids encoding them and methods for using them to inhibit angiogenesis
AU2003267993A8 (en) Monooxygenases, nucleic acids encoding them and methods for making and using them
AU2002324449A1 (en) Catalases, nucleic acids encoding them and methods for making and using them
AU2002330145A1 (en) Amidases, nucleic acids encoding them and methods for making and using them
AU2002368222A8 (en) Esterases, nucleic acids encoding them and methods of making and using them
AU2002365189A8 (en) P85-alpha nucleic acids, polypeptides and related methods
AU2002316357A1 (en) Alpha galactosides, nucleic acids encoding them and methods for making and using them
GB0110030D0 (en) RNA genomics
GB2359398B (en) Encoding method