JP2007501804A - 電位開口型のナトリウムチャネルのインヒビターとして有用な組成物 - Google Patents

電位開口型のナトリウムチャネルのインヒビターとして有用な組成物 Download PDF

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JP2007501804A
JP2007501804A JP2006522803A JP2006522803A JP2007501804A JP 2007501804 A JP2007501804 A JP 2007501804A JP 2006522803 A JP2006522803 A JP 2006522803A JP 2006522803 A JP2006522803 A JP 2006522803A JP 2007501804 A JP2007501804 A JP 2007501804A
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ring
compound
optionally substituted
aliphatic
substituents
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JP2007501804A5 (enExample
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ジーザス イー．， ザ サード ゴンザレス，
アンドレアス ピー． テルミン，
バロー， エスター マーティン
ニコル ジマーマン，
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Vertex Pharmaceuticals Inc
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Vertex Pharmaceuticals Inc
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JP2009511599A (ja) * 2005-10-12 2009-03-19 バーテックス ファーマシューティカルズ インコーポレイテッド 電位依存性イオンチャネルの調整剤としてのビフェニル誘導体
JP2010522242A (ja) * 2007-03-23 2010-07-01 ファイザー・リミテッド イオンチャネルの阻害剤
JP2010533651A (ja) * 2007-07-13 2010-10-28 アイカジェン， インコーポレイテッド ナトリウムチャネル阻害物質
JP2011500599A (ja) * 2007-10-11 2011-01-06 バーテックス ファーマシューティカルズ インコーポレイテッド 電位開口型ナトリウムチャネルの阻害剤として有用なアミド
JP2011500600A (ja) * 2007-10-11 2011-01-06 バーテックス ファーマシューティカルズ インコーポレイテッド 電位開口型ナトリウムチャネルの阻害剤として有用なアリールアミド
JP2013531029A (ja) * 2010-07-09 2013-08-01 ファイザー・リミテッド 化合物
JP2015501833A (ja) * 2011-12-15 2015-01-19 ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ スルホンアミド誘導体
JP2016506964A (ja) * 2013-01-31 2016-03-07 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ ナトリウムチャネルの調節剤としてのキノリンおよびキナゾリンアミド
JP2019502681A (ja) * 2015-12-18 2019-01-31 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． 電位作動型ナトリウムチャネルにおいて選択的活性を有する、ヒドロキシアルキルアミンおよびヒドロキシシクロアルキルアミンで置換されたジアミン−アリールスルホンアミド化合物
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