BRPI0509980A - moduladores de androgênio - Google Patents
moduladores de androgênioInfo
- Publication number
- BRPI0509980A BRPI0509980A BRPI0509980-3A BRPI0509980A BRPI0509980A BR PI0509980 A BRPI0509980 A BR PI0509980A BR PI0509980 A BRPI0509980 A BR PI0509980A BR PI0509980 A BRPI0509980 A BR PI0509980A
- Authority
- BR
- Brazil
- Prior art keywords
- modulators
- androgen
- directed
- androgen modulators
- aspects
- Prior art date
Links
- 239000003098 androgen Substances 0.000 title abstract 2
- -1 4-cyano phenoxy Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003779 hair growth Effects 0.000 abstract 1
- 210000002374 sebum Anatomy 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 239000000849 selective androgen receptor modulator Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Gynecology & Obstetrics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Virology (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Abstract
MODULADORES DE ANDROGêNIO. A presente invenção é direcionada a uma nova classe de derivados 4-ciano fenoxi de fórmula 1, e seu uso como moduladores de receptor de androgênio. Outros aspectos da invenção são direcionados ao uso destes compostos para diminuir o excesso de secreção de sebo e para estimular crescimento de cabelo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56466704P | 2004-04-22 | 2004-04-22 | |
PCT/IB2005/001044 WO2005102990A1 (en) | 2004-04-22 | 2005-04-14 | Androgen modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0509980A true BRPI0509980A (pt) | 2007-10-16 |
Family
ID=34964483
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0509980-3A BRPI0509980A (pt) | 2004-04-22 | 2005-04-14 | moduladores de androgênio |
Country Status (6)
Country | Link |
---|---|
US (1) | US7473711B2 (pt) |
EP (1) | EP1740533A1 (pt) |
JP (1) | JP2007533726A (pt) |
BR (1) | BRPI0509980A (pt) |
CA (1) | CA2562672C (pt) |
WO (1) | WO2005102990A1 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7507860B2 (en) | 2004-04-13 | 2009-03-24 | Pfizer Inc. | Androgen modulators |
JP2007533726A (ja) | 2004-04-22 | 2007-11-22 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | アンドロゲンモジュレーター |
WO2006006065A1 (en) | 2004-07-08 | 2006-01-19 | Warner-Lambert Company Llc | Androgen modulators |
BRPI0514706A (pt) * | 2004-08-31 | 2008-06-24 | Warner Lambert Co | moduladores de androgênio |
TW200724139A (en) * | 2005-05-05 | 2007-07-01 | Warner Lambert Co | Androgen modulators |
WO2007007149A1 (en) * | 2005-07-12 | 2007-01-18 | Warner-Lambert Company Llc | Androgen modulators |
US20090170886A1 (en) * | 2005-08-08 | 2009-07-02 | Pfizer Inc | Androgen modulators |
WO2024010817A2 (en) * | 2022-07-07 | 2024-01-11 | University Of Tennessee Research Foundation | Selective androgen receptor degrader (sard) o-linked ligands and methods of use thereof |
Family Cites Families (93)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2062349A1 (de) | 1970-12-18 | 1972-06-29 | Farbenfabriken Bayer Ag, 5090 Leverkusen | Aminoaryloxy-ary!carbonsäurenitrile und ein Verfahren zu ihrer Herstellung |
SU469247A3 (ru) * | 1972-01-14 | 1975-04-30 | Майлз Лабораториз Инк (Фирма) | Способ получени производных хромона |
US4029493A (en) | 1973-02-23 | 1977-06-14 | Mobil Oil Corporation | Substituted phenoxybenzonitriles as herbicides |
FR2397387A1 (fr) | 1976-04-27 | 1979-02-09 | Serobiologiques Lab Sa | 4,4'-bis-formyl-polyhalo-diphenoxyalcanes, procede de preparation et application a la synthese de 4,4'-dicyano-polyhalo-diphenoxyalcanes |
US4234595A (en) | 1977-07-13 | 1980-11-18 | Mead Johnson & Company | 3-Indolyl-tertiary butylaminopropanols |
EP0002309B1 (en) | 1977-10-12 | 1982-12-01 | Imperial Chemical Industries Plc | Acylanilides, process for their manufacture and pharmaceutical and veterinary compositions containing them |
DD150456A5 (de) | 1979-03-01 | 1981-09-02 | Ciba Geigy Ag | Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols |
US4567201A (en) * | 1981-11-25 | 1986-01-28 | Takeda Chemical Industries, Ltd. | Diphenoxypropane derivatives and compositions of antiasthmatic and antiinflammatory agents thereof |
GB8504093D0 (en) | 1985-02-18 | 1985-03-20 | Ici Plc | Alkene alkyne/cycloalkylene derivatives |
DE3372965D1 (en) | 1982-07-23 | 1987-09-17 | Ici Plc | Amide derivatives |
DE3382646D1 (de) | 1982-08-26 | 1993-01-28 | Merck Patent Gmbh | Cyclohexanderivate und ihre verwendung als komponenten fluessigkristalliner-dielektrika. |
US4536321A (en) | 1983-02-18 | 1985-08-20 | Chisso Corporation | Fluorobenzene derivatives and liquid crystal compositions containing the same |
DE3515633A1 (de) | 1985-05-02 | 1986-11-06 | Merck Patent Gmbh, 6100 Darmstadt | Benzonitrile |
IL80186A (en) | 1985-10-01 | 1990-09-17 | Ciba Geigy | Pyridinyl derivatives,their preparation and their use as microbicides |
JPS63141967A (ja) | 1986-11-21 | 1988-06-14 | エイ・エッチ・ロビンス・カンパニー・インコーポレーテッド | 抗アレルギー薬として有用な1−アリールオキシー4−[(4−アリール)−1−ピペラジニル]−2−ブタノール |
JPS63227502A (ja) | 1987-03-17 | 1988-09-21 | Sds Biotech Kk | 防菌防カビ剤 |
US4992433A (en) | 1987-11-23 | 1991-02-12 | Janssen Pharmaceutica N.V. | Novel pyridazinamine derivatives |
DE3825170A1 (de) | 1988-07-23 | 1990-01-25 | Hoechst Ag | Substituierte 5-(4-(4,5-dihydro-2-oxazolyl)-phenoxyalkylenoxyalkyl)-isoxazole, verfahren sowie 5-(phenoxyalkylenoxyalkyl)-isoxazole als zwischenprodukte zu ihrer herstellung und ihre verwendung zur bekaempfung von krankheiten, die durch infektion mit viren hervorgerufen wurden |
CA2023026A1 (en) | 1989-08-10 | 1991-02-11 | Thomas N. Wheeler | Pyridazinones having cardiotonic and beta blocking activity |
US5051431A (en) | 1989-09-22 | 1991-09-24 | Glaxo Inc. | Pyridone nitriles useful in treating cardiovascular disease |
DE4017019A1 (de) | 1990-05-26 | 1991-11-28 | Hoechst Ag | Verwendung von substituierten ss-hydroxyethylaminen als potente hemmstoffe der exoenzyme von pilzen |
JPH04124183A (ja) | 1990-09-14 | 1992-04-24 | Mitsubishi Rayon Co Ltd | 光学活性パントラクトン誘導体 |
GB9025828D0 (en) | 1990-11-28 | 1991-01-09 | Shell Int Research | Herbicidal carboxamide derivatives |
JP3088777B2 (ja) | 1991-03-27 | 2000-09-18 | 富士薬品工業株式会社 | 新規光学分割剤及びそれを用いる光学活性アミンの製造方法 |
US5320825A (en) | 1991-05-01 | 1994-06-14 | Trustees Of The University Of Pennsylvania | Serotonin reuptake inhibitors for S.P.E.C.T. imaging |
JP3151929B2 (ja) | 1992-05-15 | 2001-04-03 | 大日本インキ化学工業株式会社 | フルオロシクロヘキセン誘導体 |
DE4217928A1 (de) | 1992-05-30 | 1993-12-02 | Hoechst Ag | Neue Mischungen aus Herbiziden und Antidots, neue (Hetero-)Aryloxy-Verbindungen, Verfahren zu deren Herstellung, diese enthaltenden Mittel und deren Verwendung |
JPH0641038A (ja) | 1992-07-17 | 1994-02-15 | Mitsubishi Kasei Corp | カルボン酸誘導体 |
EP0659047A1 (en) | 1992-09-09 | 1995-06-28 | E.I. Du Pont De Nemours And Company | Herbicidal benzene compounds |
US5455274A (en) * | 1992-12-09 | 1995-10-03 | Ciba-Geigy Corporation | Hydroxyamidine derivatives |
US5326553A (en) | 1993-02-02 | 1994-07-05 | Sterling Winthrop Inc. | Compositions of iodophenoxy alkanes and iodophenyl ethers in film-forming materials for visualization of the gastrointestinal tract |
US5316755A (en) | 1993-02-02 | 1994-05-31 | Sterling Winthrop Inc. | Compositions of iodophenoxy alkanes and iodophenyl ethers for visualization of the gastrointestinal tract |
GB2278054A (en) | 1993-05-18 | 1994-11-23 | Zeneca Ltd | Compounds for the treatment of urinary incontinence |
GB9321162D0 (en) | 1993-10-13 | 1993-12-01 | Boots Co Plc | Therapeutic agents |
DE4339863A1 (de) | 1993-11-23 | 1995-05-24 | Bayer Ag | Substituierte Carbamoyltriazole |
TW262553B (pt) | 1994-03-17 | 1995-11-11 | Hitachi Seisakusyo Kk | |
WO1995028969A1 (en) | 1994-04-21 | 1995-11-02 | Nycomed Imaging As | X-ray contrast compositions containing pharmaceutically acceptable clays |
JPH07309850A (ja) | 1994-05-16 | 1995-11-28 | Canon Inc | 光学活性化合物、それを含有する液晶組成物、それを有する液晶素子及びそれらを用いた表示方法、表示装置 |
EP0684235A1 (en) | 1994-05-27 | 1995-11-29 | Mochida Pharmaceutical Co., Ltd. | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity |
SI0707007T1 (en) | 1994-10-14 | 2002-04-30 | Merck Patent Gmbh | (R)-(-)-2-(5-(4-fluorophenyl)-3-pyridylmethylaminomethyl)chromane as CNS active agent |
JP3802581B2 (ja) | 1995-03-01 | 2006-07-26 | 富山化学工業株式会社 | 新規なビフェニル誘導体またはその塩およびそれらを含有する抗炎症剤 |
JPH08325154A (ja) | 1995-03-31 | 1996-12-10 | Mitsui Toatsu Chem Inc | 安息香酸誘導体およびそれを有効成分として含有するホスホリパーゼa2阻害剤 |
DE19534209A1 (de) | 1995-09-15 | 1997-03-20 | Jenapharm Gmbh | Hormonales Mittel zur Behandlung der Haut |
EP0790235A1 (en) | 1996-02-15 | 1997-08-20 | Sankyo Company Limited | Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses |
DE19612032A1 (de) | 1996-03-27 | 1997-10-09 | Basf Ag | Substituierte 1-Methyl-3-benzyluracile |
JPH107647A (ja) | 1996-06-25 | 1998-01-13 | Yamanouchi Pharmaceut Co Ltd | 新規なチオ尿素誘導体又はその塩 |
US5847166A (en) | 1996-10-10 | 1998-12-08 | Massachusetts Institute Of Technology | Synthesis of aryl ethers |
US6071957A (en) | 1996-11-27 | 2000-06-06 | The University Of Tennessee Research Corporation | Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer |
KR100513302B1 (ko) * | 1997-02-04 | 2005-11-11 | 동화약품공업주식회사 | 3-아미노-1,2-벤조이소옥사졸 유도체, 이의 제조방법및 용도 |
US6013668A (en) | 1997-08-13 | 2000-01-11 | Bristol-Myers Squibb Company | Enantiomers of 4-[[(cyanoimino) [(1,2,2-trimethylpropyl) amino]methyl]amino]benzonitrile |
US6297239B1 (en) | 1997-10-08 | 2001-10-02 | Merck & Co., Inc. | Inhibitors of prenyl-protein transferase |
US6184249B1 (en) | 1998-12-18 | 2001-02-06 | Biophysica, Inc. | Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes |
GB9904786D0 (en) | 1999-03-02 | 1999-04-28 | Merck Sharp & Dohme | Therapeutic agents |
WO2001056989A2 (en) | 2000-02-01 | 2001-08-09 | Cor Therapeutics, Inc. | Inhibitors of factor xa |
US7060331B2 (en) | 2000-07-13 | 2006-06-13 | Merck Patent Gmbh | Chiral compounds 1 |
HUP0303385A2 (hu) | 2000-08-31 | 2004-03-01 | Pfizer Inc. | Szerotonin újrafelvételt inhibeáló fenoxibenzilamin-származékok, előállítási eljárásuk, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények |
GB0021670D0 (en) | 2000-09-04 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
KR100526091B1 (ko) | 2000-10-06 | 2005-11-08 | 다나베 세이야꾸 가부시키가이샤 | 지방족 질소 함유 오원환 화합물 |
WO2002036734A2 (en) | 2000-10-12 | 2002-05-10 | Merck & Co., Inc. | Aza-and polyaza-naphthalenyl ketones useful as hiv integrase inhibitors |
ATE337780T1 (de) | 2000-11-24 | 2006-09-15 | Smithkline Beecham Plc | Indoly-lsulphonyl-verbindungen zur behandlung von störungen des zns |
AU2002236775A1 (en) * | 2001-01-16 | 2002-07-30 | Seok-Ki Choi | Sodium channel modulators |
BR0116845A (pt) | 2001-01-31 | 2004-02-25 | Pfizer Prod Inc | Derivados éter úteis como inibidores de isozimas pde4 |
DE10110438A1 (de) | 2001-03-05 | 2002-09-19 | Bayer Ag | Substituierte 2-Oxy-3,5-dicyano-4-aryl-6-aminopyridine und ihre Verwendung |
AU2002242926B2 (en) | 2001-04-10 | 2007-10-11 | Pfizer Inc. | Pyrazole derivatives for treating HIV |
AR035700A1 (es) | 2001-05-08 | 2004-06-23 | Astrazeneca Ab | Derivados de arilheteroalquilamina, composicion farmaceutica, usos de estos derivados para la fabricacion de medicamentos, metodos de tratamiento, y proceso para la preparacion de estos derivados |
DE10126434A1 (de) | 2001-05-31 | 2002-12-05 | Bayer Ag | Thiochromenone |
US20030039814A1 (en) | 2001-07-02 | 2003-02-27 | Bader Michael John | Biaxially oriented, metallized multilayer films including non-migratory slip agent |
NL1018450C2 (nl) | 2001-07-03 | 2003-01-08 | Machf De Rollepaal B V | Inrichting voor het extruderen van een thermoplastisch polymeer tot een buis, en een spuitkop daarvoor. |
GB0202679D0 (en) | 2002-02-05 | 2002-03-20 | Glaxo Group Ltd | Novel compounds |
PT1480634E (pt) | 2002-02-07 | 2011-10-12 | Univ Tennessee Res Foundation | Moduladores selectivos do receptor do androgénio (sarms) para o tratamento da hiperplasia benigna da próstata |
TW200302722A (en) | 2002-02-13 | 2003-08-16 | Astrazeneca Ab | Therapeutic agents |
JP2005525337A (ja) | 2002-02-15 | 2005-08-25 | アンドルシェルシュ・インコーポレイテッド | ビフェニル誘導体およびその抗アンドロゲン薬としての使用 |
CA2476651A1 (en) * | 2002-02-28 | 2003-09-12 | The University Of Tennessee Research Corporation | Irreversible selective androgen receptor modulators and methods of use thereof |
AU2003230700A1 (en) | 2002-03-26 | 2003-10-13 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
EP1348701A1 (en) | 2002-03-28 | 2003-10-01 | Warner-Lambert Company LLC | (2,4-disubstituted-thiazol-5-yl) amine compounds as PDE7 inhibitors |
EP1348433A1 (en) | 2002-03-28 | 2003-10-01 | Warner-Lambert Company LLC | Thiazol-2-yl-imine compounds as PDE-7 inhibitors |
DE10218963A1 (de) | 2002-04-27 | 2003-11-20 | Aventis Pharma Gmbh | Zubereitungen zur topischen Applikation von antiandrogen wirksamen Substanzen |
US6875438B2 (en) | 2002-04-27 | 2005-04-05 | Aventis Pharma Deutschland Gmbh | Preparations for topical administration of substances having antiandrogenic activity |
AU2003262805A1 (en) * | 2002-08-26 | 2004-03-11 | Merck & Co., Inc. | Acetophenone potentiators of metabotropic glutamate receptors |
EP1638932A1 (en) | 2003-06-18 | 2006-03-29 | Pfizer Products Inc. | Novel piperazinyl-aryloxy and piperazinyl-heteroaryloxy-n-aryl lactams |
WO2005009888A2 (en) | 2003-06-27 | 2005-02-03 | King Rex Joseph Jr | Varying force counterweight system |
FI20030958A0 (fi) | 2003-06-27 | 2003-06-27 | Orion Corp | Uusia yhdisteitä |
AU2004263179B8 (en) | 2003-08-08 | 2011-07-14 | Vertex Pharmaceuticals Incorporated | Heteroarylaminosulfonylphenyl derivatives for use as sodium or calcium channel blockers in the treatment of pain |
GB0324551D0 (en) | 2003-10-21 | 2003-11-26 | Karobio Ab | Novel compounds |
WO2005049574A1 (en) | 2003-11-20 | 2005-06-02 | Warner-Lambert Company Llc | Androgen receptor modulators |
KR100783255B1 (ko) | 2004-02-13 | 2007-12-06 | 워너-램버트 캄파니 엘엘씨 | 안드로젠 수용체 조절제 |
US7507860B2 (en) | 2004-04-13 | 2009-03-24 | Pfizer Inc. | Androgen modulators |
JP2007533726A (ja) | 2004-04-22 | 2007-11-22 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | アンドロゲンモジュレーター |
US7687644B2 (en) | 2004-05-07 | 2010-03-30 | Janssen Pharmaceutica Nv | Adamantyl pyrrolidin-2-one derivatives as 11-beta hydroxysteroid dehydrogenase inhibitors |
WO2006006065A1 (en) | 2004-07-08 | 2006-01-19 | Warner-Lambert Company Llc | Androgen modulators |
MX2007001248A (es) | 2004-08-18 | 2007-03-23 | Warner Lambert Co | Moduladores de androgenos. |
BRPI0514706A (pt) | 2004-08-31 | 2008-06-24 | Warner Lambert Co | moduladores de androgênio |
TW200724139A (en) | 2005-05-05 | 2007-07-01 | Warner Lambert Co | Androgen modulators |
-
2005
- 2005-04-14 JP JP2007508998A patent/JP2007533726A/ja not_active Withdrawn
- 2005-04-14 CA CA002562672A patent/CA2562672C/en not_active Expired - Fee Related
- 2005-04-14 WO PCT/IB2005/001044 patent/WO2005102990A1/en not_active Application Discontinuation
- 2005-04-14 BR BRPI0509980-3A patent/BRPI0509980A/pt not_active IP Right Cessation
- 2005-04-14 EP EP05718484A patent/EP1740533A1/en not_active Withdrawn
- 2005-04-15 US US10/599,719 patent/US7473711B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2562672A1 (en) | 2005-11-03 |
CA2562672C (en) | 2009-09-29 |
EP1740533A1 (en) | 2007-01-10 |
US20070197642A1 (en) | 2007-08-23 |
WO2005102990A1 (en) | 2005-11-03 |
US7473711B2 (en) | 2009-01-06 |
JP2007533726A (ja) | 2007-11-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0514405A (pt) | moduladores de androgênio | |
BRPI0509980A (pt) | moduladores de androgênio | |
TW200605876A (en) | Androgen modulators | |
BRPI0509759A (pt) | moduladores de androgênio | |
EA201100944A1 (ru) | Производные изоксазола, предназначенные для применения в качестве регуляторов роста растений | |
BR112012026950A2 (pt) | composto, e, uso de um composto | |
CY1111758T1 (el) | Τρικυκλικες ενωσεις και χρηση αυτων ως ρυθμιστες υποδοχεα γλυκοκορτικοειδους | |
SV2008002986A (es) | Moduladores de indol sulfonamida de receptores de progesterona ref. x-17207 | |
BRPI0416208A (pt) | moduladores de receptores de androgênio | |
ECSP066991A (es) | 3-(4-heteroarilciclohexilamino)ciclopentanocarboxamidas como moduladores de receptores de quimiocinas | |
CO5680439A2 (es) | Derivados de ciclotiocarbamato como moduladores de pr y su uso para el tratamiento de desordenes de la piel | |
FR2968950B1 (fr) | Composition cosmetique comprenant un compose d'acide cucurbique | |
GEP20135983B (en) | 1-benzyl-3-hydroxymethylindazole derivatives and usage therein treatment of diseases based on mcp-1, cx3cr1 and p40 expression | |
PE20150289A1 (es) | Nuevos derivados de tienopirimidina, procesos para su preparacion y sus usos terapeuticos | |
WO2012143845A3 (en) | New cosmetic and therapeutical uses of ghk tripeptide | |
TW200724139A (en) | Androgen modulators | |
EP4327886A3 (en) | Pyrimido- pyridazinone compounds and use thereof | |
AU2009287650A8 (en) | Hair growth promoting agent containing 15,15 -difluoroprostaglandin F2alpha derivative as active ingredient | |
EA200601267A1 (ru) | Модуляторы рецепторов андрогена | |
WO2007017754A3 (en) | Androgen modulators | |
MX358727B (es) | Composicion cosmetica dermatologica que comprende una merocianina y una fase aceitosa que comprende al menos un compuesto amido especifico. | |
MX348961B (es) | Compuestos de aminoindano y su uso en el tratamiento del dolor. | |
WO2010001041A3 (fr) | Composition cosmétique, procédé de traitement cosmétique et composé | |
NO20070953L (no) | Androgenmodulatorer | |
UY27770A1 (es) | Imidazolinilmetil aralquilsulfonamidas |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2158 DE 15/05/2012. |