PE20050358A1 - Composiciones referidas a inhibidores de canales ionicos regulados por voltaje - Google Patents

Composiciones referidas a inhibidores de canales ionicos regulados por voltaje

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Publication number
PE20050358A1
PE20050358A1 PE2004000774A PE2004000774A PE20050358A1 PE 20050358 A1 PE20050358 A1 PE 20050358A1 PE 2004000774 A PE2004000774 A PE 2004000774A PE 2004000774 A PE2004000774 A PE 2004000774A PE 20050358 A1 PE20050358 A1 PE 20050358A1
Authority
PE
Peru
Prior art keywords
inhibitors
ion channels
referred
voltage regulated
compositions referred
Prior art date
Application number
PE2004000774A
Other languages
English (en)
Inventor
Andreas P Termin
Esther Martinborough
Iii Jesus E Gonzalez
Nicole Zimmerman
Original Assignee
Vertex Pharma
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Filing date
Publication date
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of PE20050358A1 publication Critical patent/PE20050358A1/es

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Abstract

REFERIDA A UN COMPUESTO DE FORMULA I-A DONDE RN ES H, C1-C4 ALIIFATICO OPCIONALMENTE SUSTITUIDO; X1 ES O, S O NRX; X2 ES C1-C3 ALIFATICO OPCIONALMENTE SUSTITUIDO; p ES 0-1; Z ES i, ii, ENTRE OTROS; T ES ANILLO BICICLICO O TRICICLICO, AROMATICO O NO, DE 8-14 MIEMBROS TAL COMO NAFTILO, TETRALINA, O DECALINA. SON COMPUESTOS PREFERIDOS: 4-(2,4-DICLOROFENOXI)-BUTIRATO DE ETILO; 5,7-DICLORO-INDOL-2-IL-N-[4-(TIADIAZOL-2-ILSULFAMOIL)-FENIL]AMIDA Y N-[4-(TIAZOL-2-ILSULFAMOIL)-FENIL]-2-(4-FLUOROFENOXI)-ACETAMIDA; ENTRE OTROS. TAMBIEN REFERIDO A COMPOSICIONES FARMACEUTICAS QUE COMPRENDEN DICHOS COMPUESTOS QUE SON UTILES PARA EL TRATAMIENTO DE DOLORES NEUROPATICOS E INTRATABLES
PE2004000774A 2003-08-08 2004-08-09 Composiciones referidas a inhibidores de canales ionicos regulados por voltaje PE20050358A1 (es)

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