JP2007097598A5 - - Google Patents
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- Publication number
- JP2007097598A5 JP2007097598A5 JP2007000148A JP2007000148A JP2007097598A5 JP 2007097598 A5 JP2007097598 A5 JP 2007097598A5 JP 2007000148 A JP2007000148 A JP 2007000148A JP 2007000148 A JP2007000148 A JP 2007000148A JP 2007097598 A5 JP2007097598 A5 JP 2007097598A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- ser
- acid sequence
- variable domain
- asp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0001448.0A GB0001448D0 (en) | 2000-01-21 | 2000-01-21 | Organic compounds |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001553825A Division JP3978338B2 (ja) | 2000-01-21 | 2001-01-19 | ヒトＩＬ−１βに対する抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007097598A JP2007097598A (ja) | 2007-04-19 |
| JP2007097598A5 true JP2007097598A5 (enExample) | 2007-11-15 |
Family
ID=9884137
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001553825A Expired - Fee Related JP3978338B2 (ja) | 2000-01-21 | 2001-01-19 | ヒトＩＬ−１βに対する抗体 |
| JP2007000148A Pending JP2007097598A (ja) | 2000-01-21 | 2007-01-04 | ヒトＩＬ−１βに対する抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001553825A Expired - Fee Related JP3978338B2 (ja) | 2000-01-21 | 2001-01-19 | ヒトＩＬ−１βに対する抗体 |
Country Status (33)
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0001448D0 (en) * | 2000-01-21 | 2000-03-08 | Novartis Ag | Organic compounds |
| MXPA02012867A (es) | 2000-06-29 | 2003-09-05 | Abbott Lab | Anticuerpos de especificidad doble y metodos para la elaboracion y el uso de los mismos. |
| GB0020685D0 (en) | 2000-08-22 | 2000-10-11 | Novartis Ag | Organic compounds |
| KR20040077889A (ko) * | 2002-01-28 | 2004-09-07 | 메다렉스, 인코포레이티드 | 전립선 특이적 막 항원 (ｐｓｍａ)에 대한 인간모노클로날 항체 |
| GB0303337D0 (en) | 2003-02-13 | 2003-03-19 | Celltech R&D Ltd | Biological products |
| US20060094056A1 (en) * | 2003-09-15 | 2006-05-04 | Oklahoma Medical Research Foundation | Method of using cytokine assays to diagnose treat, and evaluate inflammatory and autoimmune diseases |
| EP2857418B1 (en) | 2004-02-06 | 2017-07-26 | University of Massachusetts | Antibodies against Clostridium difficile toxins and uses thereof |
| EP1851245B1 (en) * | 2005-01-26 | 2012-10-10 | Amgen Fremont Inc. | Antibodies against interleukin-1 beta |
| PA8672101A1 (es) * | 2005-04-29 | 2006-12-07 | Centocor Inc | Anticuerpos anti-il-6, composiciones, métodos y usos |
| ES2569917T3 (es) * | 2005-06-21 | 2016-05-13 | Xoma (Us) Llc | Anticuerpos y fragmentos de los mismos que se unen a IL-1beta |
| EP2848258B1 (en) * | 2005-10-26 | 2017-12-13 | Novartis AG | Treatment of familial Mediterranean Fever with anti IL-1beta antibodies |
| RS55963B1 (sr) * | 2005-12-29 | 2017-09-29 | Janssen Biotech Inc | Humana anti-il-23 antitela, kompozicije, metode i upotrebe |
| US7943328B1 (en) | 2006-03-03 | 2011-05-17 | Prometheus Laboratories Inc. | Method and system for assisting in diagnosing irritable bowel syndrome |
| AU2007238677B2 (en) * | 2006-04-14 | 2011-03-10 | Novartis Ag | Use of IL-I antibodies for treating ophthalmic disorders |
| US20080085524A1 (en) * | 2006-08-15 | 2008-04-10 | Prometheus Laboratories Inc. | Methods for diagnosing irritable bowel syndrome |
| EP3124045A3 (en) | 2006-12-20 | 2017-05-03 | Xoma (Us) Llc | Treatment of il-1 beta related diseases |
| EP2114443A4 (en) * | 2006-12-29 | 2011-08-10 | Abbott Lab | IL-1A / IL-1B ANTIBODY WITH DOUBLE SPECIFICITY |
| CA2679400A1 (en) | 2007-02-28 | 2008-09-04 | Schering Corporation | Combination therapy for treatment of immune disorders |
| EP3406263A1 (en) * | 2007-05-29 | 2018-11-28 | Novartis AG | New indications for anti-il-1beta therapy |
| DK2391650T3 (en) * | 2007-12-20 | 2015-01-12 | Xoma Us Llc | Methods of treating gout |
| CA2727171A1 (en) * | 2008-06-06 | 2009-12-10 | Xoma Technology Ltd. | Methods for the treatment of rheumatoid arthritis |
| CA2735939A1 (en) | 2008-09-05 | 2010-03-11 | Xoma Technology Ltd. | Methods for improvement of beta cell function |
| CN104928336B (zh) | 2009-10-26 | 2020-05-08 | 弗·哈夫曼-拉罗切有限公司 | 用于生产糖基化免疫球蛋白的方法 |
| WO2011140522A1 (en) * | 2010-05-07 | 2011-11-10 | Xoma Technology Ltd. | METHODS FOR THE TREATMENT OF IL-1β RELATED CONDITIONS |
| DE102010033565B4 (de) * | 2010-07-27 | 2012-06-21 | Tetec Tissue Engineering Technologies Ag | Marker zur Bestimmung von Chondrozyten |
| KR102306967B1 (ko) | 2010-08-02 | 2021-10-01 | 리제너론 파아마슈티컬스, 인크. | Ｖｌ 도메인을 포함하는 결합 단백질을 생성하는 마우스 |
| EP2614085B1 (en) | 2010-09-10 | 2016-04-20 | Apexigen, Inc. | Anti-il-1 beta antibodies and methods of use |
| LT2738259T (lt) | 2011-02-25 | 2020-03-10 | Regeneron Pharmaceuticals, Inc. | Adam6 pelės |
| PT3865581T (pt) | 2011-08-05 | 2024-10-04 | Regeneron Pharma | Murganhos da cadeia leve universal humanizada |
| DE102011083595A1 (de) | 2011-09-28 | 2013-03-28 | Bayer Pharma AG | Inhibition der Wirkung von Interleukin 1 beta zur Behandlung der Endometriose |
| JP6320300B2 (ja) | 2011-12-19 | 2018-05-09 | ゾーマ （ユーエス） リミテッド ライアビリティ カンパニー | 座瘡を治療するための方法 |
| PT3527070T (pt) | 2011-12-20 | 2025-12-19 | Regeneron Pharma | Murganhos de cadeia leve humanizada |
| PT2814843T (pt) | 2012-02-13 | 2020-06-18 | Agency Science Tech & Res | Anticorpos monoclonais humanos neutralizantes de il-b |
| EP3912464A1 (en) | 2012-06-12 | 2021-11-24 | Regeneron Pharmaceuticals, Inc. | Humanized non-human animals with restricted immunoglobulin heavy chain loci |
| CN106255410B (zh) | 2014-03-21 | 2020-01-10 | 瑞泽恩制药公司 | 产生单结构域结合蛋白的非人动物 |
| CN106164092A (zh) | 2014-03-21 | 2016-11-23 | 瑞泽恩制药公司 | 表现不同结合特征的vl抗原结合蛋白 |
| US11111314B2 (en) | 2015-03-19 | 2021-09-07 | Regeneron Pharmaceuticals, Inc. | Non-human animals that select for light chain variable regions that bind antigen |
| ES3064335T3 (en) | 2018-03-05 | 2026-04-24 | Janssen Biotech Inc | Methods of treating crohn's disease with anti-il23 specific antibody |
| CN110818793A (zh) | 2018-08-14 | 2020-02-21 | 中山康方生物医药有限公司 | 抗IL-1β的抗体、其药物组合物及其用途 |
| MX2021005905A (es) | 2018-11-20 | 2021-06-23 | Janssen Biotech Inc | Metodo seguro y eficaz para tratar la psoriasis con el anticuerpo especifico anti-il-23. |
| US11780911B2 (en) | 2019-05-23 | 2023-10-10 | Janssen Biotech, Inc. | Method of treating inflammatory bowel disease with a combination therapy of antibodies to IL-23 and TNF alpha |
| MX2022014430A (es) | 2020-05-21 | 2023-02-22 | Janssen Biotech Inc | Método para tratar la enfermedad inflamatoria del intestino con una terapia de combinación de anticuerpos para il-23 y tnf alfa. |
| CN116063489B (zh) * | 2022-10-21 | 2026-01-30 | 杭州靶向食品科技有限公司 | 一种治疗痛风的单克隆抗体及其相应的组合物 |
| CN121511262A (zh) | 2023-06-28 | 2026-02-10 | 北京哲源科技有限责任公司 | 靶向pd-l1和il-1的双特异性抗体及其用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4772685A (en) | 1985-10-02 | 1988-09-20 | Merck & Co., Inc. | Immunogenic peptides of human interleukin-1 and the corresponding anti-peptide antibodies |
| US4935343A (en) * | 1986-08-08 | 1990-06-19 | Syntex (U.S.A.) Inc. | Monoclonal antibodies for interleukin-1β |
| FR2640146B1 (fr) * | 1988-12-08 | 1993-12-24 | Commissariat A Energie Atomique | Anticorps monoclonaux anti-interleukines 1(alpha) et 1(beta), leur procede de production et applications desdits anticorps a la detection des interleukines 1(alpha) et 1(beta) et en therapeutique |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| GB9014932D0 (en) | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| JP3714683B2 (ja) * | 1992-07-30 | 2005-11-09 | 生化学工業株式会社 | 抗リウマチ剤 |
| US5429614A (en) | 1993-06-30 | 1995-07-04 | Baxter International Inc. | Drug delivery system |
| WO1995001997A1 (en) * | 1993-07-09 | 1995-01-19 | Smithkline Beecham Corporation | RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN |
| US6051228A (en) | 1998-02-19 | 2000-04-18 | Bristol-Myers Squibb Co. | Antibodies against human CD40 |
| GB0001448D0 (en) * | 2000-01-21 | 2000-03-08 | Novartis Ag | Organic compounds |
-
2000
- 2000-01-21 GB GBGB0001448.0A patent/GB0001448D0/en not_active Ceased
-
2001
- 2001-01-18 CO CO01003434A patent/CO5261584A1/es active IP Right Grant
- 2001-01-18 MY MYPI20010226A patent/MY155269A/en unknown
- 2001-01-19 US US10/181,324 patent/US20030124617A1/en not_active Abandoned
- 2001-01-19 PT PT01905671T patent/PT1248804E/pt unknown
- 2001-01-19 ES ES01905671T patent/ES2274865T5/es not_active Expired - Lifetime
- 2001-01-19 JP JP2001553825A patent/JP3978338B2/ja not_active Expired - Fee Related
- 2001-01-19 AR ARP010100247A patent/AR027253A1/es active IP Right Grant
- 2001-01-19 TR TR2002/01780T patent/TR200201780T2/xx unknown
- 2001-01-19 AU AU33697/01A patent/AU772949B2/en not_active Ceased
- 2001-01-19 WO PCT/EP2001/000591 patent/WO2001053353A2/en not_active Ceased
- 2001-01-19 KR KR1020027009374A patent/KR100697126B1/ko not_active Expired - Fee Related
- 2001-01-19 EP EP01905671A patent/EP1248804B2/en not_active Expired - Lifetime
- 2001-01-19 BR BR0107661-2A patent/BR0107661A/pt not_active IP Right Cessation
- 2001-01-19 AT AT01905671T patent/ATE346868T1/de active
- 2001-01-19 SI SI200130698T patent/SI1248804T2/sl unknown
- 2001-01-19 CA CA2396212A patent/CA2396212C/en not_active Expired - Fee Related
- 2001-01-19 HU HU0204156A patent/HUP0204156A3/hu not_active Application Discontinuation
- 2001-01-19 RU RU2002121649/13A patent/RU2264413C2/ru not_active IP Right Cessation
- 2001-01-19 CZ CZ20022531A patent/CZ302738B6/cs not_active IP Right Cessation
- 2001-01-19 NZ NZ519936A patent/NZ519936A/en not_active IP Right Cessation
- 2001-01-19 DK DK01905671.2T patent/DK1248804T4/da active
- 2001-01-19 PL PL356297A patent/PL207642B1/pl unknown
- 2001-01-19 CN CN018039529A patent/CN1395581B/zh not_active Expired - Fee Related
- 2001-01-19 SK SK1035-2002A patent/SK288054B6/sk not_active IP Right Cessation
- 2001-01-19 MX MXPA02007091A patent/MXPA02007091A/es active IP Right Grant
- 2001-01-19 PE PE2001000065A patent/PE20011219A1/es not_active Application Discontinuation
- 2001-01-19 HK HK03102022.5A patent/HK1050013A1/zh unknown
- 2001-01-19 DE DE60124863T patent/DE60124863T3/de not_active Expired - Lifetime
- 2001-01-19 IL IL15055101A patent/IL150551A0/xx unknown
-
2002
- 2002-07-02 IL IL150551A patent/IL150551A/en not_active IP Right Cessation
- 2002-07-05 NO NO20023266A patent/NO329816B1/no not_active IP Right Cessation
- 2002-07-16 ZA ZA2002/05659A patent/ZA200205659B/en unknown
-
2006
- 2006-07-11 US US11/484,472 patent/US7491392B2/en not_active Expired - Fee Related
- 2006-12-29 CY CY20061101860T patent/CY1107989T1/el unknown
-
2007
- 2007-01-04 JP JP2007000148A patent/JP2007097598A/ja active Pending
-
2009
- 2009-01-09 US US12/351,007 patent/US20090232803A1/en not_active Abandoned
-
2011
- 2011-03-10 US US13/044,918 patent/US20110182894A1/en not_active Abandoned