JP2007097598A5 - - Google Patents
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- Publication number
- JP2007097598A5 JP2007097598A5 JP2007000148A JP2007000148A JP2007097598A5 JP 2007097598 A5 JP2007097598 A5 JP 2007097598A5 JP 2007000148 A JP2007000148 A JP 2007000148A JP 2007000148 A JP2007000148 A JP 2007000148A JP 2007097598 A5 JP2007097598 A5 JP 2007097598A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- ser
- acid sequence
- variable domain
- asp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0001448.0A GB0001448D0 (en) | 2000-01-21 | 2000-01-21 | Organic compounds |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001553825A Division JP3978338B2 (ja) | 2000-01-21 | 2001-01-19 | ヒトＩＬ−１βに対する抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007097598A JP2007097598A (ja) | 2007-04-19 |
| JP2007097598A5 true JP2007097598A5 (enExample) | 2007-11-15 |
Family
ID=9884137
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001553825A Expired - Fee Related JP3978338B2 (ja) | 2000-01-21 | 2001-01-19 | ヒトＩＬ−１βに対する抗体 |
| JP2007000148A Pending JP2007097598A (ja) | 2000-01-21 | 2007-01-04 | ヒトＩＬ−１βに対する抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001553825A Expired - Fee Related JP3978338B2 (ja) | 2000-01-21 | 2001-01-19 | ヒトＩＬ−１βに対する抗体 |
Country Status (33)
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0001448D0 (en) * | 2000-01-21 | 2000-03-08 | Novartis Ag | Organic compounds |
| PE20020132A1 (es) | 2000-06-29 | 2002-03-04 | Abbott Lab | Anticuerpos de especificidad doble y metodos para la elaboracion y el uso de los mismos |
| GB0020685D0 (en) | 2000-08-22 | 2000-10-11 | Novartis Ag | Organic compounds |
| EP1519747A4 (en) * | 2002-01-28 | 2006-03-29 | Medarex Inc | HUMAN MONOCLONAL ANTIBODIES AGAINST PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA) |
| GB0303337D0 (en) | 2003-02-13 | 2003-03-19 | Celltech R&D Ltd | Biological products |
| EP2280286A1 (en) * | 2003-09-15 | 2011-02-02 | Oklahoma Medical Research Foundation | Method of using cytokine assays to diagnose, treat, and evaluate systemic lupus erythematosus |
| ES2366626T3 (es) | 2004-02-06 | 2011-10-24 | University Of Massachusetts | Anticuerpos contra toxinas de clostridium difficile y usos de los mismos. |
| EP2361933A3 (en) * | 2005-01-26 | 2012-05-02 | Amgen Fremont Inc. | Antibodies against interleukin-1 beta |
| PA8672101A1 (es) * | 2005-04-29 | 2006-12-07 | Centocor Inc | Anticuerpos anti-il-6, composiciones, métodos y usos |
| ES2335232T3 (es) | 2005-06-21 | 2010-03-23 | Xoma Technology Ltd. | Anticuerpos y fragmentos de los mismos que se unen a la il-1 beta. |
| CA2963828A1 (en) * | 2005-10-26 | 2007-05-03 | Novartis Ag | Novel use of il-1beta compounds |
| SI3219328T1 (sl) | 2005-12-29 | 2020-10-30 | Janssen Biotech, Inc. | Človeška protitelesa proti-IL-23, sestavki, postopki in uporabe |
| US7943328B1 (en) | 2006-03-03 | 2011-05-17 | Prometheus Laboratories Inc. | Method and system for assisting in diagnosing irritable bowel syndrome |
| KR20110079922A (ko) * | 2006-04-14 | 2011-07-11 | 노파르티스 아게 | 안과 장애 치료를 위한 ｉｌ－1 항체의 용도 |
| US20080085524A1 (en) * | 2006-08-15 | 2008-04-10 | Prometheus Laboratories Inc. | Methods for diagnosing irritable bowel syndrome |
| WO2008077145A2 (en) | 2006-12-20 | 2008-06-26 | Xoma Technology Ltd. | Treatment of il-1-beta related diseases |
| WO2008082651A2 (en) * | 2006-12-29 | 2008-07-10 | Abbott Laboratories | Dual-specific il-1a/ il-1b antibodies |
| MX2009009167A (es) | 2007-02-28 | 2009-09-04 | Schering Corp | Terapia de combinacion para el tratamiento de trastornos inmunes. |
| WO2008145664A1 (en) * | 2007-05-29 | 2008-12-04 | Novartis Ag | New indications for anti- il-i-beta therapy |
| RU2018100129A (ru) | 2007-12-20 | 2019-02-20 | Ксома (Сша) Ллс | Способы лечения подагры |
| HRP20130042T1 (hr) * | 2008-06-06 | 2013-03-31 | Xoma Technology Ltd. | Postupci lijeäśenja reumatoidnog artritisa |
| AU2009289547A1 (en) | 2008-09-05 | 2010-03-11 | Xoma (Us) Llc | Methods for treating or preventing IL-1beta related diseases |
| US20110117087A1 (en) | 2009-10-26 | 2011-05-19 | Reinhard Franze | Method for the production of a glycosylated immunoglobulin |
| BR112012028557A2 (pt) * | 2010-05-07 | 2019-09-24 | Xoma Technology Ltd. | uso de um anticorpo anti-il-1b ou de fragmentos de ligação do mesmo. |
| DE102010033565B4 (de) * | 2010-07-27 | 2012-06-21 | Tetec Tissue Engineering Technologies Ag | Marker zur Bestimmung von Chondrozyten |
| EP2601298B1 (en) | 2010-08-02 | 2016-11-30 | Regeneron Pharmaceuticals, Inc. | Mice that make binding proteins comprising vl domains |
| WO2012034039A2 (en) * | 2010-09-10 | 2012-03-15 | Apexigen, Inc. | Anti-il-1 beta antibodies and methods of use |
| CN105861548B (zh) | 2011-02-25 | 2020-01-10 | 瑞泽恩制药公司 | Adam6小鼠 |
| ES2872081T3 (es) | 2011-08-05 | 2021-11-02 | Regeneron Pharma | Ratones con cadena ligera universal humanizada |
| DE102011083595A1 (de) | 2011-09-28 | 2013-03-28 | Bayer Pharma AG | Inhibition der Wirkung von Interleukin 1 beta zur Behandlung der Endometriose |
| CN104144946A (zh) | 2011-12-19 | 2014-11-12 | 爱克索马美国有限责任公司 | 治疗痤疮的方法 |
| SMT201900296T1 (it) | 2011-12-20 | 2019-07-11 | Regeneron Pharma | Topi di catena leggera umanizzata |
| SG10201708562VA (en) | 2012-02-13 | 2017-12-28 | Agency Science Tech & Res | IL-1β Neutralizing Human Monoclonal Antibodies |
| NZ703689A (en) | 2012-06-12 | 2016-05-27 | Regeneron Pharma | Humanized non-human animals with restricted immunoglobulin heavy chain loci |
| AU2015230938C1 (en) | 2014-03-21 | 2021-10-14 | Regeneron Pharmaceuticals, Inc. | Non-human animals that make single domain binding proteins |
| SG10201808083VA (en) | 2014-03-21 | 2018-10-30 | Regeneron Pharma | Vl antigen binding proteins exhibiting distinct binding characteristics |
| CN107438622A (zh) | 2015-03-19 | 2017-12-05 | 瑞泽恩制药公司 | 选择结合抗原的轻链可变区的非人动物 |
| JP7516250B2 (ja) | 2018-03-05 | 2024-07-16 | ヤンセン バイオテツク，インコーポレーテツド | 抗ｉｌ－２３特異的抗体を用いたクローン病の治療方法 |
| CN110818793A (zh) * | 2018-08-14 | 2020-02-21 | 中山康方生物医药有限公司 | 抗IL-1β的抗体、其药物组合物及其用途 |
| MA55149A (fr) | 2018-11-20 | 2021-09-29 | Janssen Biotech Inc | Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique anti-il-23 |
| EP3972690A4 (en) | 2019-05-23 | 2023-07-05 | Janssen Biotech, Inc. | METHOD OF TREATMENT OF INFLAMMATORY BOWEL DISEASE USING COMBINATION THERAPY OF ANTIBODIES TO IL-23 AND TNF-ALPHA |
| CA3183927A1 (en) | 2020-05-21 | 2021-11-25 | Janssen Biotech, Inc. | Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha |
| CN116063489B (zh) * | 2022-10-21 | 2026-01-30 | 杭州靶向食品科技有限公司 | 一种治疗痛风的单克隆抗体及其相应的组合物 |
| JP2026521932A (ja) | 2023-06-28 | 2026-07-02 | フィル リバーズ テクノロジー カンパニー リミテッド | Ｐｄ－ｌ１及びｉｌ－１を標的とする二重特異性抗体及びその使用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4772685A (en) | 1985-10-02 | 1988-09-20 | Merck & Co., Inc. | Immunogenic peptides of human interleukin-1 and the corresponding anti-peptide antibodies |
| US4935343A (en) * | 1986-08-08 | 1990-06-19 | Syntex (U.S.A.) Inc. | Monoclonal antibodies for interleukin-1β |
| FR2640146B1 (fr) * | 1988-12-08 | 1993-12-24 | Commissariat A Energie Atomique | Anticorps monoclonaux anti-interleukines 1(alpha) et 1(beta), leur procede de production et applications desdits anticorps a la detection des interleukines 1(alpha) et 1(beta) et en therapeutique |
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| GB9014932D0 (en) | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| JP3714683B2 (ja) * | 1992-07-30 | 2005-11-09 | 生化学工業株式会社 | 抗リウマチ剤 |
| US5429614A (en) | 1993-06-30 | 1995-07-04 | Baxter International Inc. | Drug delivery system |
| WO1995001997A1 (en) * | 1993-07-09 | 1995-01-19 | Smithkline Beecham Corporation | RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN |
| US6051228A (en) | 1998-02-19 | 2000-04-18 | Bristol-Myers Squibb Co. | Antibodies against human CD40 |
| GB0001448D0 (en) * | 2000-01-21 | 2000-03-08 | Novartis Ag | Organic compounds |
-
2000
- 2000-01-21 GB GBGB0001448.0A patent/GB0001448D0/en not_active Ceased
-
2001
- 2001-01-18 MY MYPI20010226A patent/MY155269A/en unknown
- 2001-01-18 CO CO01003434A patent/CO5261584A1/es active IP Right Grant
- 2001-01-19 WO PCT/EP2001/000591 patent/WO2001053353A2/en not_active Ceased
- 2001-01-19 PT PT01905671T patent/PT1248804E/pt unknown
- 2001-01-19 US US10/181,324 patent/US20030124617A1/en not_active Abandoned
- 2001-01-19 DE DE60124863T patent/DE60124863T3/de not_active Expired - Lifetime
- 2001-01-19 AU AU33697/01A patent/AU772949B2/en not_active Ceased
- 2001-01-19 DK DK01905671.2T patent/DK1248804T4/da active
- 2001-01-19 AR ARP010100247A patent/AR027253A1/es active IP Right Grant
- 2001-01-19 RU RU2002121649/13A patent/RU2264413C2/ru not_active IP Right Cessation
- 2001-01-19 CZ CZ20022531A patent/CZ302738B6/cs not_active IP Right Cessation
- 2001-01-19 TR TR2002/01780T patent/TR200201780T2/xx unknown
- 2001-01-19 IL IL15055101A patent/IL150551A0/xx unknown
- 2001-01-19 KR KR1020027009374A patent/KR100697126B1/ko not_active Expired - Fee Related
- 2001-01-19 SI SI200130698T patent/SI1248804T2/sl unknown
- 2001-01-19 HK HK03102022.5A patent/HK1050013A1/zh unknown
- 2001-01-19 AT AT01905671T patent/ATE346868T1/de active
- 2001-01-19 CA CA2396212A patent/CA2396212C/en not_active Expired - Fee Related
- 2001-01-19 EP EP01905671A patent/EP1248804B2/en not_active Expired - Lifetime
- 2001-01-19 HU HU0204156A patent/HUP0204156A3/hu not_active Application Discontinuation
- 2001-01-19 ES ES01905671T patent/ES2274865T5/es not_active Expired - Lifetime
- 2001-01-19 CN CN018039529A patent/CN1395581B/zh not_active Expired - Fee Related
- 2001-01-19 PL PL356297A patent/PL207642B1/pl unknown
- 2001-01-19 JP JP2001553825A patent/JP3978338B2/ja not_active Expired - Fee Related
- 2001-01-19 SK SK1035-2002A patent/SK288054B6/sk not_active IP Right Cessation
- 2001-01-19 NZ NZ519936A patent/NZ519936A/en not_active IP Right Cessation
- 2001-01-19 MX MXPA02007091A patent/MXPA02007091A/es active IP Right Grant
- 2001-01-19 BR BR0107661-2A patent/BR0107661A/pt not_active IP Right Cessation
- 2001-01-19 PE PE2001000065A patent/PE20011219A1/es not_active Application Discontinuation
-
2002
- 2002-07-02 IL IL150551A patent/IL150551A/en not_active IP Right Cessation
- 2002-07-05 NO NO20023266A patent/NO329816B1/no not_active IP Right Cessation
- 2002-07-16 ZA ZA2002/05659A patent/ZA200205659B/en unknown
-
2006
- 2006-07-11 US US11/484,472 patent/US7491392B2/en not_active Expired - Fee Related
- 2006-12-29 CY CY20061101860T patent/CY1107989T1/el unknown
-
2007
- 2007-01-04 JP JP2007000148A patent/JP2007097598A/ja active Pending
-
2009
- 2009-01-09 US US12/351,007 patent/US20090232803A1/en not_active Abandoned
-
2011
- 2011-03-10 US US13/044,918 patent/US20110182894A1/en not_active Abandoned