|
US7655249B2
(en)
|
1998-09-30 |
2010-02-02 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
|
US7329410B1
(en)
|
1998-09-30 |
2008-02-12 |
Corixa Corporation |
Compositions and method for WT1 specific immunotherapy
|
|
US7063854B1
(en)
|
1998-09-30 |
2006-06-20 |
Corixa Corporation |
Composition and methods for WTI specific immunotherapy
|
|
US7144581B2
(en)
|
2000-10-09 |
2006-12-05 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
|
US7901693B2
(en)
|
1998-09-30 |
2011-03-08 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
|
US7115272B1
(en)
|
1998-09-30 |
2006-10-03 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
|
AU2001263155A1
(en)
*
|
2000-05-16 |
2001-11-26 |
Massachusetts Institute Of Technology |
Methods and compositions for interaction trap assays
|
|
US7029847B2
(en)
|
2000-05-16 |
2006-04-18 |
Massachusetts Institute Of Technology |
Methods and compositions for interaction trap assays
|
|
AU2002225187A1
(en)
*
|
2001-01-22 |
2002-07-30 |
Sangamo Biosciences, Inc. |
Zinc finger polypeptides and their use
|
|
JP4128955B2
(ja)
*
|
2001-08-17 |
2008-07-30 |
トゥールゲン・インコーポレイテッド |
ジンクフィンガードメインライブラリー
|
|
US7553494B2
(en)
|
2001-08-24 |
2009-06-30 |
Corixa Corporation |
WT1 fusion proteins
|
|
CA2469477A1
(en)
*
|
2001-12-07 |
2003-06-12 |
Toolgen, Inc. |
Phenotypic screen of chimeric proteins
|
|
US8799501B2
(en)
*
|
2002-04-30 |
2014-08-05 |
Hewlett-Packard Development Company, L. P. |
System and method for anonymously sharing and scoring information pointers, within a system for harvesting community knowledge
|
|
WO2003104414A2
(en)
*
|
2002-06-11 |
2003-12-18 |
The Scripps Research Institute |
Artificial transcription factors
|
|
AU2003260973A1
(en)
*
|
2002-09-05 |
2004-03-29 |
Toolgen, Inc. |
Bioinformatics analysis of cellular effects of artificial transcription factors
|
|
AU2003302752A1
(en)
*
|
2002-12-09 |
2004-06-30 |
Toolgen, Inc. |
Regulatory zinc finger proteins
|
|
US20060182736A1
(en)
*
|
2003-06-10 |
2006-08-17 |
Kim Jin-Soo |
Transducible dna-binding proteins
|
|
US7888121B2
(en)
|
2003-08-08 |
2011-02-15 |
Sangamo Biosciences, Inc. |
Methods and compositions for targeted cleavage and recombination
|
|
US20120196370A1
(en)
|
2010-12-03 |
2012-08-02 |
Fyodor Urnov |
Methods and compositions for targeted genomic deletion
|
|
ES2808687T3
(es)
|
2003-08-08 |
2021-03-01 |
Sangamo Therapeutics Inc |
Métodos y composiciones para escisión dirigida y recombinación
|
|
CA2539439C
(en)
|
2003-09-19 |
2012-10-23 |
Sangamo Biosciences, Inc. |
Engineered zinc finger proteins for regulation of gene expression
|
|
WO2005061705A1
(en)
*
|
2003-12-23 |
2005-07-07 |
Toolgen, Inc. |
Regulation of prokaryotic gene expression with zinc finger proteins
|
|
JP4903689B2
(ja)
*
|
2004-04-08 |
2012-03-28 |
サンガモ バイオサイエンシズ インコーポレイテッド |
神経障害および神経変性症状を治療するための方法と組成物
|
|
KR100857125B1
(ko)
|
2004-05-25 |
2008-09-11 |
주식회사 툴젠 |
단일클론 항체 생산을 증가시키는 폴리펩타이드, 이를코드하는 핵산 및 이의 용도
|
|
AU2005287278B2
(en)
|
2004-09-16 |
2011-08-04 |
Sangamo Biosciences, Inc. |
Compositions and methods for protein production
|
|
US20090263900A1
(en)
|
2008-04-14 |
2009-10-22 |
Sangamo Biosciences, Inc. |
Linear donor constructs for targeted integration
|
|
EP1913149A4
(en)
|
2005-07-26 |
2009-08-05 |
Sangamo Biosciences Inc |
TARGETED INTEGRATION AND EXPRESSION OF EXOGENOUS NUCLEIC ACID SEQUENCES
|
|
EP2019839B1
(en)
|
2006-05-25 |
2011-12-07 |
Sangamo BioSciences, Inc. |
Methods and compositions for gene inactivation
|
|
DE602007005634D1
(de)
|
2006-05-25 |
2010-05-12 |
Sangamo Biosciences Inc |
Variante foki-spaltungshälften-domänen
|
|
CA2660485C
(en)
|
2006-08-11 |
2016-04-12 |
Sangamo Biosciences, Inc. |
Zinc finger nuclease-mediated homologous recombination
|
|
KR100812110B1
(ko)
*
|
2006-10-24 |
2008-03-12 |
한국과학기술원 |
징크 핑거 단백질과 원핵 생물의 전사 인자를 포함하는인공 전사 인자의 제조 및 이의 이용
|
|
US9217026B2
(en)
|
2006-11-13 |
2015-12-22 |
Sangamo Biosciences, Inc. |
Method of inactivating a glucocorticoid receptor gene in an isolated cell
|
|
US9187758B2
(en)
|
2006-12-14 |
2015-11-17 |
Sangamo Biosciences, Inc. |
Optimized non-canonical zinc finger proteins
|
|
US8110379B2
(en)
|
2007-04-26 |
2012-02-07 |
Sangamo Biosciences, Inc. |
Targeted integration into the PPP1R12C locus
|
|
CN101883850B
(zh)
|
2007-07-12 |
2014-11-12 |
桑格摩生物科学股份有限公司 |
用于失活α-1,6岩藻糖基转移酶(FUT8)基因表达的方法和组合物
|
|
US8563314B2
(en)
|
2007-09-27 |
2013-10-22 |
Sangamo Biosciences, Inc. |
Methods and compositions for modulating PD1
|
|
CN101883863B
(zh)
|
2007-09-27 |
2018-01-23 |
桑格摩生物科学股份有限公司 |
生物活性核酸酶的快速体内鉴定
|
|
DK2205749T3
(en)
|
2007-09-27 |
2016-08-22 |
Dow Agrosciences Llc |
MODIFIED PROTEINS zinc finger, which target the 5-enolpyruvylshikimate-3-phosphate synthase genes
|
|
US11235026B2
(en)
|
2007-09-27 |
2022-02-01 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modulating PD1
|
|
CA2703045C
(en)
|
2007-10-25 |
2017-02-14 |
Sangamo Biosciences, Inc. |
Methods and compositions for targeted integration
|
|
ES2594229T3
(es)
|
2008-04-30 |
2016-12-16 |
Sanbio, Inc. |
Células de regeneración nerviosa con alteraciones en la metilación del ADN
|
|
JP2011521643A
(ja)
|
2008-05-28 |
2011-07-28 |
サンガモ バイオサイエンシーズ， インコーポレイテッド |
Ｄｎａ結合ドメインおよび切断ドメインを連結するための組成物
|
|
JP5763530B2
(ja)
|
2008-06-10 |
2015-08-12 |
サンガモ バイオサイエンシーズ， インコーポレイテッド |
Ｂａｘ−およびＢａｋ−欠損細胞株の生成のための方法および組成物
|
|
SG191561A1
(en)
|
2008-08-22 |
2013-07-31 |
Sangamo Biosciences Inc |
Methods and compositions for targeted single-stranded cleavage and targeted integration
|
|
CN102264915B
(zh)
|
2008-10-29 |
2014-04-16 |
桑格摩生物科学股份有限公司 |
失活谷氨酰胺合成酶基因表达的方法和组合物
|
|
JP5681114B2
(ja)
|
2008-12-04 |
2015-03-04 |
サンガモ バイオサイエンシーズ， インコーポレイテッド |
亜鉛フィンガーヌクレアーゼを使用したラットのゲノム編集
|
|
ES2654923T3
(es)
|
2008-12-17 |
2018-02-15 |
Dow Agrosciences Llc |
Integración dirigida en la localización Zp15
|
|
EP3354275B1
(en)
|
2009-02-04 |
2019-10-30 |
Sangamo Therapeutics, Inc. |
Methods and compositions for treating neuropathies
|
|
AU2010226313B2
(en)
|
2009-03-20 |
2014-10-09 |
Sangamo Therapeutics, Inc. |
Modification of CXCR4 using engineered zinc finger proteins
|
|
JP6215533B2
(ja)
|
2009-04-09 |
2017-10-18 |
サンガモ セラピューティクス， インコーポレイテッド |
幹細胞への標的組込み
|
|
US8772008B2
(en)
|
2009-05-18 |
2014-07-08 |
Sangamo Biosciences, Inc. |
Methods and compositions for increasing nuclease activity
|
|
WO2011002503A1
(en)
|
2009-06-30 |
2011-01-06 |
Sangamo Biosciences, Inc. |
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells
|
|
US9234016B2
(en)
|
2009-07-28 |
2016-01-12 |
Sangamo Biosciences, Inc. |
Engineered zinc finger proteins for treating trinucleotide repeat disorders
|
|
NZ598457A
(en)
|
2009-08-03 |
2014-06-27 |
Recombinetics Inc |
Methods and compositions for targeted gene modification
|
|
EP3428289B1
(en)
|
2009-08-11 |
2020-05-20 |
Sangamo Therapeutics, Inc. |
Organisms homozygous for targeted modification
|
|
RU2712833C2
(ru)
|
2009-10-22 |
2020-01-31 |
ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи |
Конструируемые белки с цинковыми пальцами, направленные на гены растений, вовлеченные в биосинтез жирных кислот
|
|
US8956828B2
(en)
|
2009-11-10 |
2015-02-17 |
Sangamo Biosciences, Inc. |
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
|
|
NZ601247A
(en)
|
2010-01-22 |
2014-10-31 |
Dow Agrosciences Llc |
Targeted genomic alteration
|
|
FR2955480B1
(fr)
|
2010-01-26 |
2012-01-06 |
Christian Choux |
Dispositif d'osteosynthese de la paroi thoracique
|
|
DK2534173T3
(da)
|
2010-02-08 |
2019-10-14 |
Sangamo Therapeutics Inc |
Manipulerede spaltnings-halvdomæner
|
|
EP2534163B1
(en)
|
2010-02-09 |
2015-11-04 |
Sangamo BioSciences, Inc. |
Targeted genomic modification with partially single-stranded donor molecules
|
|
KR101880536B1
(ko)
|
2010-04-26 |
2018-07-23 |
상가모 테라퓨틱스, 인코포레이티드 |
아연 핑거 뉴클레아제를 사용하는 로사 좌위의 게놈 편집
|
|
KR101974036B1
(ko)
|
2010-05-03 |
2019-04-30 |
상가모 테라퓨틱스, 인코포레이티드 |
아연 핑거 모듈을 연결하기 위한 조성물
|
|
JP6208580B2
(ja)
|
2010-05-17 |
2017-10-04 |
サンガモ セラピューティクス， インコーポレイテッド |
新規のｄｎａ結合タンパク質及びその使用
|
|
CA2993567C
(en)
|
2010-07-21 |
2022-06-28 |
Sangamo Biosciences, Inc. |
Methods and compositions for modification of a t-cell receptor gene
|
|
CA2811364C
(en)
|
2010-09-27 |
2022-01-04 |
Sangamo Biosciences, Inc. |
Methods and compositions for inhibiting viral entry into cells
|
|
CN103270046B
(zh)
|
2010-10-12 |
2016-05-11 |
费城儿童医院 |
治疗b型血友病的方法和组合物
|
|
US9267123B2
(en)
|
2011-01-05 |
2016-02-23 |
Sangamo Biosciences, Inc. |
Methods and compositions for gene correction
|
|
US20140186340A1
(en)
|
2011-04-08 |
2014-07-03 |
Gilead Biologics, Inc. |
Methods and Compositions for Normalization of Tumor Vasculature by Inhibition of LOXL2
|
|
WO2013016446A2
(en)
|
2011-07-25 |
2013-01-31 |
Sangamo Biosciences, Inc. |
Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (cftr) gene
|
|
CA2848417C
(en)
|
2011-09-21 |
2023-05-02 |
Sangamo Biosciences, Inc. |
Methods and compositions for regulation of transgene expression
|
|
AU2012323032A1
(en)
*
|
2011-10-11 |
2014-04-03 |
Aliophtha Ag |
Regulation of receptor expression through delivery of artificial transcription factors
|
|
CA2852955C
(en)
|
2011-10-27 |
2021-02-16 |
Sangamo Biosciences, Inc. |
Methods and compositions for modification of the hprt locus
|
|
JP6144691B2
(ja)
|
2011-11-16 |
2017-06-07 |
サンガモ セラピューティクス， インコーポレイテッド |
修飾されたｄｎａ結合タンパク質およびその使用
|
|
CA2862309A1
(en)
|
2012-01-27 |
2013-08-01 |
Sanbio, Inc. |
Methods and compositions for modulating angiogenesis and vasculogenesis
|
|
NZ629427A
(en)
|
2012-02-29 |
2016-04-29 |
Sangamo Biosciences Inc |
Methods and compositions for treating huntington’s disease
|
|
CN102634535B
(zh)
*
|
2012-04-12 |
2014-11-26 |
西北农林科技大学 |
一种基于锌指蛋白插入载体的随机锌指蛋白库的构建方法
|
|
KR102091298B1
(ko)
|
2012-05-02 |
2020-03-19 |
다우 아그로사이언시즈 엘엘씨 |
말산 탈수소효소의 표적화된 변형
|
|
CA2871524C
(en)
|
2012-05-07 |
2021-07-27 |
Sangamo Biosciences, Inc. |
Methods and compositions for nuclease-mediated targeted integration of transgenes
|
|
US10648001B2
(en)
|
2012-07-11 |
2020-05-12 |
Sangamo Therapeutics, Inc. |
Method of treating mucopolysaccharidosis type I or II
|
|
EP2872154B1
(en)
|
2012-07-11 |
2017-05-31 |
Sangamo BioSciences, Inc. |
Methods and compositions for delivery of biologics
|
|
HUE051612T2
(hu)
|
2012-07-11 |
2021-03-01 |
Sangamo Therapeutics Inc |
Eljárások és készítmények lizoszomális tárolási betegségek kezelésére
|
|
PL2890780T3
(pl)
|
2012-08-29 |
2021-02-08 |
Sangamo Therapeutics, Inc. |
Sposoby i kompozycje do leczenia zaburzeń genetycznych
|
|
UA118090C2
(uk)
|
2012-09-07 |
2018-11-26 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив
|
|
BR112015004995B1
(pt)
|
2012-09-07 |
2023-05-02 |
Sangamo Biosciences, Inc. |
Método para modificação do genoma de uma célula, uso de uma célula, semente ou planta obtida pelo referido método e nuclease de dedo de zinco sítio específica
|
|
UA119135C2
(uk)
|
2012-09-07 |
2019-05-10 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб отримання трансгенної рослини
|
|
AU2013329186B2
(en)
|
2012-10-10 |
2019-02-14 |
Sangamo Therapeutics, Inc. |
T cell modifying compounds and uses thereof
|
|
CA2892448A1
(en)
|
2012-12-05 |
2014-06-12 |
Sangamo Biosciences, Inc. |
Methods and compositions for regulation of metabolic disorders
|
|
CA2895117A1
(en)
|
2012-12-13 |
2014-06-19 |
James W. Bing |
Precision gene targeting to a particular locus in maize
|
|
JP6491113B2
(ja)
|
2013-02-25 |
2019-03-27 |
サンガモ セラピューティクス， インコーポレイテッド |
ヌクレアーゼ媒介性遺伝子破壊を増強するための方法および組成物
|
|
WO2014153470A2
(en)
|
2013-03-21 |
2014-09-25 |
Sangamo Biosciences, Inc. |
Targeted disruption of t cell receptor genes using engineered zinc finger protein nucleases
|
|
US10501748B2
(en)
|
2013-04-05 |
2019-12-10 |
Dow Agrosciences Llc |
Methods and compositions for integration of an exogenous sequence within the genome of plants
|
|
CN116083487A
(zh)
|
2013-05-15 |
2023-05-09 |
桑格摩生物治疗股份有限公司 |
用于治疗遗传病状的方法和组合物
|
|
CA2920899C
(en)
|
2013-08-28 |
2023-02-28 |
Sangamo Biosciences, Inc. |
Compositions for linking dna-binding domains and cleavage domains
|
|
CA2926078C
(en)
|
2013-10-17 |
2021-11-16 |
Sangamo Biosciences, Inc. |
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells
|
|
CN105899665B
(zh)
|
2013-10-17 |
2019-10-22 |
桑格摩生物科学股份有限公司 |
用于核酸酶介导的基因组工程改造的递送方法和组合物
|
|
WO2015066634A2
(en)
|
2013-11-04 |
2015-05-07 |
Dow Agrosciences Llc |
Optimal soybean loci
|
|
EP3066110B1
(en)
|
2013-11-04 |
2021-12-29 |
Corteva Agriscience LLC |
Optimal maize loci
|
|
KR102269769B1
(ko)
|
2013-11-04 |
2021-06-28 |
코르테바 애그리사이언스 엘엘씨 |
최적 메이즈 유전자좌
|
|
EP3066202B1
(en)
|
2013-11-04 |
2021-03-03 |
Dow AgroSciences LLC |
Optimal soybean loci
|
|
NZ719477A
(en)
|
2013-11-11 |
2022-05-27 |
Sangamo Therapeutics Inc |
Methods and compositions for treating huntington’s disease
|
|
PL3068881T3
(pl)
|
2013-11-13 |
2019-08-30 |
Children's Medical Center Corporation |
Regulacja ekspresji genów, w której pośredniczą nukleazy
|
|
EP3080274B1
(en)
|
2013-12-09 |
2020-06-03 |
Sangamo Therapeutics, Inc. |
Methods and compositions for genome engineering
|
|
AU2015218576B2
(en)
|
2014-02-24 |
2020-02-27 |
Sangamo Therapeutics, Inc. |
Methods and compositions for nuclease-mediated targeted integration
|
|
ES2879373T3
(es)
|
2014-03-18 |
2021-11-22 |
Sangamo Therapeutics Inc |
Métodos y composiciones para la regulación de la expresión de proteínas de dedo de zinc
|
|
US9522936B2
(en)
|
2014-04-24 |
2016-12-20 |
Sangamo Biosciences, Inc. |
Engineered transcription activator like effector (TALE) proteins
|
|
MX378789B
(es)
|
2014-05-08 |
2025-03-11 |
Sangamo Biosciences Inc |
Métodos y composiciones para tratar la enfermedad de huntington.
|
|
AU2015259191B2
(en)
|
2014-05-13 |
2019-03-21 |
Sangamo Therapeutics, Inc. |
Methods and compositions for prevention or treatment of a disease
|
|
EP3152319A4
(en)
|
2014-06-05 |
2017-12-27 |
Sangamo BioSciences, Inc. |
Methods and compositions for nuclease design
|
|
US20170159065A1
(en)
|
2014-07-08 |
2017-06-08 |
Vib Vzw |
Means and methods to increase plant yield
|
|
CA2955203C
(en)
|
2014-07-14 |
2022-01-04 |
Washington State University |
Nanos knock-out that ablates germline cells
|
|
US11278572B2
(en)
|
2014-07-18 |
2022-03-22 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Reducing CXCR4 expression and/or function to enhance engraftment of hematopoietic stem cells
|
|
US9757420B2
(en)
|
2014-07-25 |
2017-09-12 |
Sangamo Therapeutics, Inc. |
Gene editing for HIV gene therapy
|
|
US9816074B2
(en)
|
2014-07-25 |
2017-11-14 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modulating nuclease-mediated genome engineering in hematopoietic stem cells
|
|
WO2016019144A2
(en)
|
2014-07-30 |
2016-02-04 |
Sangamo Biosciences, Inc. |
Gene correction of scid-related genes in hematopoietic stem and progenitor cells
|
|
CN113699113A
(zh)
|
2014-09-16 |
2021-11-26 |
桑格摩治疗股份有限公司 |
用于造血干细胞中核酸酶介导的基因组工程化和校正的方法和组合物
|
|
US10889834B2
(en)
|
2014-12-15 |
2021-01-12 |
Sangamo Therapeutics, Inc. |
Methods and compositions for enhancing targeted transgene integration
|
|
EP3247366A4
(en)
|
2015-01-21 |
2018-10-31 |
Sangamo Therapeutics, Inc. |
Methods and compositions for identification of highly specific nucleases
|
|
ES2959608T3
(es)
|
2015-04-03 |
2024-02-27 |
Dana Farber Cancer Inst Inc |
Composición y métodos de edición del genoma de células B
|
|
US10179918B2
(en)
|
2015-05-07 |
2019-01-15 |
Sangamo Therapeutics, Inc. |
Methods and compositions for increasing transgene activity
|
|
EP3294866A4
(en)
|
2015-05-12 |
2018-12-05 |
Sangamo Therapeutics, Inc. |
Nuclease-mediated regulation of gene expression
|
|
US9957501B2
(en)
|
2015-06-18 |
2018-05-01 |
Sangamo Therapeutics, Inc. |
Nuclease-mediated regulation of gene expression
|
|
AU2016291778B2
(en)
|
2015-07-13 |
2021-05-06 |
Sangamo Therapeutics, Inc. |
Delivery methods and compositions for nuclease-mediated genome engineering
|
|
EP3331355B1
(en)
|
2015-08-06 |
2024-04-03 |
The Curators of the University of Missouri |
Porcine reproductive and respiratory syndrome virus (prrsv)-resistant porcine and cells having modified cd163 genes
|
|
US10435441B2
(en)
|
2015-09-23 |
2019-10-08 |
Sangamo Therapeutics, Inc. |
HTT repressors and uses thereof
|
|
JP6976249B2
(ja)
|
2015-11-23 |
2021-12-08 |
サンガモ セラピューティクス， インコーポレイテッド |
免疫を工学操作するための方法および組成物
|
|
MX2018007519A
(es)
|
2015-12-18 |
2019-09-04 |
Sangamo Therapeutics Inc |
Alteracion dirigida del receptor celular del complejo mayor de histocompatibilidad (mhc).
|
|
WO2017106528A2
(en)
|
2015-12-18 |
2017-06-22 |
Sangamo Biosciences, Inc. |
Targeted disruption of the t cell receptor
|
|
ES2895430T3
(es)
|
2016-01-15 |
2022-02-21 |
Univ Minnesota |
Métodos y composiciones para el tratamiento de enfermedad neurológica
|
|
JP7012650B2
(ja)
|
2016-02-02 |
2022-01-28 |
サンガモ セラピューティクス， インコーポレイテッド |
Ｄｎａ結合ドメインと切断ドメインとを連結するための組成物
|
|
EP3433362B1
(en)
|
2016-03-23 |
2021-05-05 |
Dana-Farber Cancer Institute, Inc. |
Methods for enhancing the efficiency of gene editing
|
|
AU2017295720B2
(en)
|
2016-07-13 |
2021-07-22 |
Vertex Pharmaceuticals Incorporated |
Methods, compositions and kits for increasing genome editing efficiency
|
|
CN109789128A
(zh)
|
2016-07-27 |
2019-05-21 |
凯斯西储大学 |
促进髓鞘形成的化合物和方法
|
|
US11193136B2
(en)
|
2016-08-09 |
2021-12-07 |
Vib Vzw |
Cellulose synthase inhibitors and mutant plants
|
|
SG11201901364VA
(en)
|
2016-08-24 |
2019-03-28 |
Sangamo Therapeutics Inc |
Engineered target specific nucleases
|
|
CR20190098A
(es)
|
2016-08-24 |
2019-04-30 |
Sangamo Therapeutics Inc |
Regulación de la expresión génica usando nucleasas modificadas
|
|
WO2018049009A2
(en)
|
2016-09-07 |
2018-03-15 |
Sangamo Therapeutics, Inc. |
Modulation of liver genes
|
|
MA46354A
(fr)
|
2016-10-03 |
2019-08-07 |
Juno Therapeutics Inc |
Molécules se liant spécifiquement au vph
|
|
ES2811500T3
(es)
|
2016-10-04 |
2021-03-12 |
Prec Biosciences Inc |
Dominios coestimuladores para su uso en células genéticamente modificadas
|
|
JP7042263B2
(ja)
|
2016-10-20 |
2022-03-25 |
サンガモ セラピューティクス， インコーポレイテッド |
ファブリー病の治療のための方法および組成物
|
|
EP3532106A4
(en)
|
2016-10-31 |
2020-06-24 |
Sangamo Therapeutics, Inc. |
GENERAL CORRECTION OF SCID-ASSOCIATED GENES IN HEMOTOPOIETIC STEM CELLS AND PROCUREMENT CELLS
|
|
KR102674612B1
(ko)
|
2016-12-01 |
2024-06-14 |
상가모 테라퓨틱스, 인코포레이티드 |
Tau 조절제 및 그것의 전달을 위한 방법 및 조성물
|
|
CN110249051A
(zh)
|
2016-12-08 |
2019-09-17 |
凯斯西储大学 |
增强功能性髓鞘产生的方法和组合物
|
|
WO2018195418A1
(en)
|
2017-04-20 |
2018-10-25 |
Oregon Health & Science University |
Human gene correction
|
|
CA3059793A1
(en)
|
2017-05-03 |
2018-11-08 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modification of a cystic fibrosis transmembrane conductance regulator (cftr) gene
|
|
WO2018208837A1
(en)
|
2017-05-08 |
2018-11-15 |
Precision Biosciences, Inc. |
Nucleic acid molecules encoding an engineered antigen receptor and an inhibitory nucleic acid molecule and methods of use thereof
|
|
US11512287B2
(en)
|
2017-06-16 |
2022-11-29 |
Sangamo Therapeutics, Inc. |
Targeted disruption of T cell and/or HLA receptors
|
|
CA3068465A1
(en)
|
2017-06-30 |
2019-01-03 |
Precision Biosciences, Inc. |
Genetically-modified t cells comprising a modified intron in the t cell receptor alpha gene
|
|
WO2019032675A1
(en)
|
2017-08-08 |
2019-02-14 |
Sangamo Therapeutics, Inc. |
CELL TARGETING MEDIATED BY A CHIMERIC ANTIGEN RECEPTOR
|
|
CN111954679A
(zh)
|
2017-10-03 |
2020-11-17 |
朱诺治疗学股份有限公司 |
Hpv特异性结合分子
|
|
US20200239544A1
(en)
|
2017-10-03 |
2020-07-30 |
Precision Biosciences, Inc. |
Modified epidermal growth factor receptor peptides for use in genetically-modified cells
|
|
WO2019089913A1
(en)
|
2017-11-01 |
2019-05-09 |
Precision Biosciences, Inc. |
Engineered nucleases that target human and canine factor viii genes as a treatment for hemophilia a
|
|
JP2021502085A
(ja)
|
2017-11-09 |
2021-01-28 |
サンガモ セラピューティクス， インコーポレイテッド |
サイトカイン誘導性ｓｈ２含有タンパク質（ｃｉｓｈ）遺伝子の遺伝子改変
|
|
SG11202004926WA
(en)
|
2017-12-01 |
2020-06-29 |
Encoded Therapeutics Inc |
Engineered dna binding proteins
|
|
EP3728587A4
(en)
|
2017-12-18 |
2022-01-26 |
Syngenta Participations Ag |
SITES FOR TARGETED INSERTION IN THE MAIZE GENOME
|
|
BR112020014315A2
(pt)
|
2018-01-17 |
2020-12-08 |
Vertex Pharmaceuticals Incorporated |
Inibidores de dna-pk
|
|
EA202091709A1
(ru)
|
2018-01-17 |
2020-11-10 |
Вертекс Фармасьютикалз Инкорпорейтед |
Ингибиторы днк-пк
|
|
ES2940786T3
(es)
|
2018-01-17 |
2023-05-11 |
Vertex Pharma |
Compuestos de quinoxalinona, composiciones, métodos y kits para aumentar la eficiencia de edición del genoma
|
|
MX2020008272A
(es)
|
2018-02-08 |
2020-09-21 |
Sangamo Therapeutics Inc |
Nucleasas diseñadas específicas de blancos.
|
|
EP3775237A1
(en)
|
2018-04-05 |
2021-02-17 |
Juno Therapeutics, Inc. |
T cells expressing a recombinant receptor, related polynucleotides and methods
|
|
KR20210029707A
(ko)
|
2018-04-05 |
2021-03-16 |
주노 쎄러퓨티크스 인코퍼레이티드 |
재조합 수용체를 발현하는 세포의 생산 방법 및 관련 조성물
|
|
TWI840351B
(zh)
|
2018-04-05 |
2024-05-01 |
美商奇諾治療有限公司 |
T細胞受體及表現其之工程化細胞
|
|
WO2019204457A1
(en)
|
2018-04-18 |
2019-10-24 |
Sangamo Therapeutics, Inc. |
Zinc finger protein compositions for modulation of huntingtin (htt)
|
|
US11690921B2
(en)
|
2018-05-18 |
2023-07-04 |
Sangamo Therapeutics, Inc. |
Delivery of target specific nucleases
|
|
KR102712986B1
(ko)
|
2018-08-23 |
2024-10-07 |
상가모 테라퓨틱스, 인코포레이티드 |
조작된 표적 특이적 염기 편집기
|
|
AU2019344927A1
(en)
|
2018-09-18 |
2021-04-01 |
Sangamo Therapeutics, Inc. |
Programmed cell death 1 (PD1) specific nucleases
|
|
EP4613367A1
(en)
|
2018-09-21 |
2025-09-10 |
Acuitas Therapeutics, Inc. |
Systems and methods for manufacturing lipid nanoparticles and liposomes
|
|
EP3860618B1
(en)
|
2018-10-02 |
2026-02-04 |
Sangamo Therapeutics, Inc. |
Compositions for treating tauopathy
|
|
EP3898661A1
(en)
|
2018-12-21 |
2021-10-27 |
Precision BioSciences, Inc. |
Genetic modification of the hydroxyacid oxidase 1 gene for treatment of primary hyperoxaluria
|
|
CA3125485A1
(en)
|
2019-01-11 |
2020-07-16 |
Acuitas Therapeutics, Inc. |
Lipids for lipid nanoparticle delivery of active agents
|
|
EP3826664A4
(en)
|
2019-02-06 |
2022-10-26 |
Sangamo Therapeutics, Inc. |
Method for the treatment of mucopolysaccharidosis type i
|
|
WO2020205838A1
(en)
|
2019-04-02 |
2020-10-08 |
Sangamo Therapeutics, Inc. |
Methods for the treatment of beta-thalassemia
|
|
KR20240122580A
(ko)
|
2019-04-03 |
2024-08-12 |
프리시젼 바이오사이언시스 인코포레이티드 |
마이크로RNA-적응 shRNA(shRNAmiR)를 포함하는 유전자-변형 면역 세포
|
|
US20220204994A1
(en)
|
2019-04-05 |
2022-06-30 |
Precision Biosciences, Inc. |
Methods of preparing populations of genetically-modified immune cells
|
|
PE20212332A1
(es)
|
2019-04-23 |
2021-12-14 |
Sangamo Therapeutics Inc |
Moduladores de la expresioon del gen de marco de lectura abierto 72 del cromosoma 9 y usos de los mismos
|
|
AU2020265749A1
(en)
|
2019-05-01 |
2022-01-06 |
Juno Therapeutics, Inc. |
Cells expressing a chimeric receptor from a modified CD247 locus, related polynucleotides and methods
|
|
SG11202111360YA
(en)
|
2019-05-01 |
2021-11-29 |
Juno Therapeutics Inc |
Cells expressing a recombinant receptor from a modified tgfbr2 locus, related polynucleotides and methods
|
|
BR112021024055A2
(pt)
|
2019-05-29 |
2022-02-08 |
Encoded Therapeutics Inc |
Composições e métodos para a regulação seletiva de gene
|
|
WO2021016608A1
(en)
|
2019-07-25 |
2021-01-28 |
Precision Biosciences, Inc. |
Compositions and methods for sequential stacking of nucleic acid sequences into a genomic locus
|
|
CA3148179A1
(en)
|
2019-08-20 |
2021-02-25 |
Bruce J. Mccreedy Jr. |
Lymphodepletion dosing regimens for cellular immunotherapies
|
|
WO2021035170A1
(en)
|
2019-08-21 |
2021-02-25 |
Precision Biosciences, Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
US20220324928A1
(en)
|
2019-10-02 |
2022-10-13 |
Sangamo Therapeutics, Inc. |
Zinc Finger Protein Transcription Factors for Repressing Alpha-Synuclein Expression
|
|
US20230002459A1
(en)
|
2019-10-02 |
2023-01-05 |
Sangamo Therapeutics, Inc. |
Zinc Finger Protein Transcription Factors for Treatment of Prion Disease
|
|
US20220411479A1
(en)
|
2019-10-30 |
2022-12-29 |
Precision Biosciences, Inc. |
Cd20 chimeric antigen receptors and methods of use for immunotherapy
|
|
WO2021087358A1
(en)
|
2019-11-01 |
2021-05-06 |
Sangamo Therapeutics, Inc. |
Gin recombinase variants
|
|
US20230036065A1
(en)
|
2019-12-06 |
2023-02-02 |
Precision Biosciences, Inc. |
Methods for cancer immunotherapy
|
|
TW202134288A
(zh)
|
2020-01-22 |
2021-09-16 |
美商聖加莫治療股份有限公司 |
用於抑制tau蛋白表現之鋅指蛋白轉錄因子
|
|
WO2021158915A1
(en)
|
2020-02-06 |
2021-08-12 |
Precision Biosciences, Inc. |
Recombinant adeno-associated virus compositions and methods for producing and using the same
|
|
US20230263121A1
(en)
|
2020-03-31 |
2023-08-24 |
Elo Life Systems |
Modulation of endogenous mogroside pathway genes in watermelon and other cucurbits
|
|
CA3177093A1
(en)
|
2020-05-06 |
2021-11-11 |
Cellectis S.A. |
Methods for targeted insertion of exogenous sequences in cellular genomes
|
|
EP4146284A1
(en)
|
2020-05-06 |
2023-03-15 |
Cellectis S.A. |
Methods to genetically modify cells for delivery of therapeutic proteins
|
|
US20230183664A1
(en)
|
2020-05-11 |
2023-06-15 |
Precision Biosciences, Inc. |
Self-limiting viral vectors encoding nucleases
|
|
JP2023526278A
(ja)
|
2020-05-13 |
2023-06-21 |
ジュノー セラピューティクス インコーポレイテッド |
組み換え受容体を発現しているドナーバッチ細胞を産生するための方法
|
|
EP4171616A1
(en)
|
2020-06-26 |
2023-05-03 |
Juno Therapeutics GmbH |
Engineered t cells conditionally expressing a recombinant receptor, related polynucleotides and methods
|
|
DK4182297T3
(da)
|
2020-07-16 |
2025-12-01 |
Acuitas Therapeutics Inc |
Kationiske lipider til brug i lipid-nanopartikler
|
|
US20260028412A1
(en)
|
2020-08-10 |
2026-01-29 |
Precision Biosciences, Inc. |
Antibodies and fragments specific for b-cell maturation antigen and uses thereof
|
|
US12152251B2
(en)
|
2020-08-25 |
2024-11-26 |
Kite Pharma, Inc. |
T cells with improved functionality
|
|
EP4217479A1
(en)
|
2020-09-25 |
2023-08-02 |
Sangamo Therapeutics, Inc. |
Zinc finger fusion proteins for nucleobase editing
|
|
WO2022076547A1
(en)
|
2020-10-07 |
2022-04-14 |
Precision Biosciences, Inc. |
Lipid nanoparticle compositions
|
|
US20240060079A1
(en)
|
2020-10-23 |
2024-02-22 |
Elo Life Systems |
Methods for producing vanilla plants with improved flavor and agronomic production
|
|
JP2023549780A
(ja)
|
2020-11-04 |
2023-11-29 |
ジュノー セラピューティクス インコーポレイテッド |
改変されたインバリアントｃｄ３免疫グロブリンスーパーファミリー鎖遺伝子座からキメラ受容体を発現する細胞ならびに関連するポリヌクレオチドおよび方法
|
|
MX2023005665A
(es)
|
2020-11-16 |
2023-08-01 |
Pig Improvement Co Uk Ltd |
Animales resistentes a la influenza a que tienen genes de anp32 editados.
|
|
WO2022165111A1
(en)
|
2021-01-28 |
2022-08-04 |
Precision Biosciences, Inc. |
Modulation of tgf beta signaling in genetically-modified eukaryotic cells
|
|
US20240141311A1
(en)
|
2021-04-22 |
2024-05-02 |
North Carolina State University |
Compositions and methods for generating male sterile plants
|
|
WO2023064872A1
(en)
|
2021-10-14 |
2023-04-20 |
Precision Biosciences, Inc. |
Combinations of anti-bcma car t cells and gamma secretase inhibitors
|
|
US20240408235A1
(en)
|
2021-10-19 |
2024-12-12 |
Precision Biosciences, Inc. |
Gene editing methods for treating alpha-1 antitrypsin (aat) deficiency
|
|
WO2023081900A1
(en)
|
2021-11-08 |
2023-05-11 |
Juno Therapeutics, Inc. |
Engineered t cells expressing a recombinant t cell receptor (tcr) and related systems and methods
|
|
US20250009800A1
(en)
|
2021-11-16 |
2025-01-09 |
Precision Biosciences, Inc. |
Methods for cancer immunotherapy
|
|
WO2023105244A1
(en)
|
2021-12-10 |
2023-06-15 |
Pig Improvement Company Uk Limited |
Editing tmprss2/4 for disease resistance in livestock
|
|
WO2023114943A2
(en)
|
2021-12-16 |
2023-06-22 |
Acuitas Therapeutics, Inc. |
Lipids for use in lipid nanoparticle formulations
|
|
CN118591626A
(zh)
|
2021-12-22 |
2024-09-03 |
桑格摩生物治疗股份有限公司 |
用于核碱基编辑的新型锌指融合蛋白
|
|
WO2023131616A1
(en)
|
2022-01-05 |
2023-07-13 |
Vib Vzw |
Means and methods to increase abiotic stress tolerance in plants
|
|
WO2023131637A1
(en)
|
2022-01-06 |
2023-07-13 |
Vib Vzw |
Improved silage grasses
|
|
WO2023144199A1
(en)
|
2022-01-26 |
2023-08-03 |
Vib Vzw |
Plants having reduced levels of bitter taste metabolites
|
|
WO2024013514A2
(en)
|
2022-07-15 |
2024-01-18 |
Pig Improvement Company Uk Limited |
Gene edited livestock animals having coronavirus resistance
|
|
EP4615960A1
(en)
|
2022-11-09 |
2025-09-17 |
C3S2 GmbH |
Methods for manufacturing engineered immune cells
|
|
CN121002052A
(zh)
|
2023-02-03 |
2025-11-21 |
C3S2 有限公司 |
用于非病毒生产工程化免疫细胞的方法
|
|
CN121311497A
(zh)
|
2023-04-14 |
2026-01-09 |
精密生物科学公司 |
肌肉特异性表达盒
|
|
WO2024216116A1
(en)
|
2023-04-14 |
2024-10-17 |
Precision Biosciences, Inc. |
Muscle-specific expression cassettes
|
|
WO2024238723A1
(en)
|
2023-05-16 |
2024-11-21 |
Omega Therapeutics, Inc. |
Methods and compositions for modulating pcsk9 expression
|
|
WO2024238726A1
(en)
|
2023-05-16 |
2024-11-21 |
Omega Therapeutics, Inc. |
Methods and compositions for modulating methylation of a target gene
|
|
WO2025004001A1
(en)
|
2023-06-30 |
2025-01-02 |
Takeda Pharmaceutical Company Limited |
Htt repressors and uses thereof
|
|
WO2025019742A1
(en)
|
2023-07-19 |
2025-01-23 |
Omega Therapeutics, Inc. |
Methods and compositions for modulating ctnnb1 expression
|
|
WO2025194124A1
(en)
|
2024-03-14 |
2025-09-18 |
Tessera Therapeutics, Inc. |
Modified st1cas9 guide nucleic acids
|
|
WO2025235563A1
(en)
|
2024-05-07 |
2025-11-13 |
Omega Therapeutics, Inc. |
Epigenetic modulation for upregulation of genes
|
|
WO2025235851A1
(en)
|
2024-05-10 |
2025-11-13 |
Juno Therapeutics, Inc. |
Genetically engineered t cells expressing a cd19 chimeric antigen receptor (car) and uses thereof for allogeneic cell therapy
|