US7144581B2
(en)
|
2000-10-09 |
2006-12-05 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
US7901693B2
(en)
|
1998-09-30 |
2011-03-08 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
US7063854B1
(en)
|
1998-09-30 |
2006-06-20 |
Corixa Corporation |
Composition and methods for WTI specific immunotherapy
|
US7655249B2
(en)
|
1998-09-30 |
2010-02-02 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
US7329410B1
(en)
|
1998-09-30 |
2008-02-12 |
Corixa Corporation |
Compositions and method for WT1 specific immunotherapy
|
US7115272B1
(en)
|
1998-09-30 |
2006-10-03 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
AU2001263155A1
(en)
*
|
2000-05-16 |
2001-11-26 |
Massachusetts Institute Of Technology |
Methods and compositions for interaction trap assays
|
US7029847B2
(en)
|
2000-05-16 |
2006-04-18 |
Massachusetts Institute Of Technology |
Methods and compositions for interaction trap assays
|
US7947469B2
(en)
*
|
2001-01-22 |
2011-05-24 |
Gendaq, Ltd. |
Modulation of HIV infection
|
KR100961722B1
(ko)
*
|
2001-08-17 |
2010-06-10 |
주식회사 툴젠 |
징크 핑거 도메인 라이브러리
|
US7553494B2
(en)
|
2001-08-24 |
2009-06-30 |
Corixa Corporation |
WT1 fusion proteins
|
CN100463962C
(zh)
*
|
2001-12-07 |
2009-02-25 |
图尔金株式会社 |
嵌合蛋白质的表型筛选
|
US8799501B2
(en)
*
|
2002-04-30 |
2014-08-05 |
Hewlett-Packard Development Company, L. P. |
System and method for anonymously sharing and scoring information pointers, within a system for harvesting community knowledge
|
EP1532178A4
(en)
*
|
2002-06-11 |
2006-10-25 |
Scripps Research Inst |
ARTIFICIAL TRANSCRIPTION FACTORS
|
AU2003260973A1
(en)
*
|
2002-09-05 |
2004-03-29 |
Toolgen, Inc. |
Bioinformatics analysis of cellular effects of artificial transcription factors
|
EP1570058A1
(en)
*
|
2002-12-09 |
2005-09-07 |
Toolgen, Inc. |
Regulatory zinc finger proteins
|
WO2004108883A2
(en)
*
|
2003-06-10 |
2004-12-16 |
Toolgen, Inc. |
Transducible dna-binding proteins
|
US7888121B2
(en)
|
2003-08-08 |
2011-02-15 |
Sangamo Biosciences, Inc. |
Methods and compositions for targeted cleavage and recombination
|
JP4555292B2
(ja)
|
2003-08-08 |
2010-09-29 |
サンガモ バイオサイエンシズ インコーポレイテッド |
標的化された切断及び組換えの方法及び組成物
|
US20120196370A1
(en)
|
2010-12-03 |
2012-08-02 |
Fyodor Urnov |
Methods and compositions for targeted genomic deletion
|
US7407776B2
(en)
|
2003-09-19 |
2008-08-05 |
Sangamo Biosciences, Inc. |
Engineered zinc finger proteins for regulation of gene expression
|
US20070042378A1
(en)
*
|
2003-12-23 |
2007-02-22 |
Kim Jin-Soo |
Regulation of prokaryotic gene expression with zinc finger proteins
|
AU2005232665B2
(en)
*
|
2004-04-08 |
2010-05-13 |
Sangamo Therapeutics, Inc. |
Methods and compositions for treating neuropathic and neurodegenerative conditions
|
KR100857125B1
(ko)
|
2004-05-25 |
2008-09-11 |
주식회사 툴젠 |
단일클론 항체 생산을 증가시키는 폴리펩타이드, 이를코드하는 핵산 및 이의 용도
|
AU2005287278B2
(en)
|
2004-09-16 |
2011-08-04 |
Sangamo Biosciences, Inc. |
Compositions and methods for protein production
|
AU2006272634B2
(en)
|
2005-07-26 |
2013-01-24 |
Sangamo Therapeutics, Inc. |
Targeted integration and expression of exogenous nucleic acid sequences
|
EP2213731B1
(en)
|
2006-05-25 |
2013-12-04 |
Sangamo BioSciences, Inc. |
Variant foki cleavage half-domains
|
JP5551432B2
(ja)
|
2006-05-25 |
2014-07-16 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
遺伝子不活性化のための方法と組成物
|
PL2049663T3
(pl)
|
2006-08-11 |
2015-08-31 |
Dow Agrosciences Llc |
Homologiczna rekombinacja za pośrednictwem nukleazy z palcami cynkowymi
|
KR100812110B1
(ko)
*
|
2006-10-24 |
2008-03-12 |
한국과학기술원 |
징크 핑거 단백질과 원핵 생물의 전사 인자를 포함하는인공 전사 인자의 제조 및 이의 이용
|
AU2007319881B2
(en)
|
2006-11-13 |
2012-05-17 |
Sangamo Therapeutics, Inc. |
Zinc finger nuclease for targeting the human glucocorticoid receptor locus
|
HUE029238T2
(en)
|
2006-12-14 |
2017-02-28 |
Dow Agrosciences Llc |
Optimized non-canonical zinc finger proteins
|
CA2684378C
(en)
|
2007-04-26 |
2016-11-29 |
Sangamo Biosciences, Inc. |
Targeted integration into the ppp1r12c locus
|
AU2008275649B2
(en)
|
2007-07-12 |
2013-09-05 |
Sangamo Therapeutics, Inc. |
Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT 8) gene expression
|
CN101883863B
(zh)
|
2007-09-27 |
2018-01-23 |
桑格摩生物科学股份有限公司 |
生物活性核酸酶的快速体内鉴定
|
US8563314B2
(en)
|
2007-09-27 |
2013-10-22 |
Sangamo Biosciences, Inc. |
Methods and compositions for modulating PD1
|
BRPI0817560B1
(pt)
|
2007-09-27 |
2022-09-20 |
Dow Agrosciences Llc |
Proteínas de dedo de zinco (zfp) engenheiradas que têm como alvo genes de 5-enolpiruvil shiquimato-3-fosfato sintase, nuclease de dedo de zinco (zfn), vetor, bem como métodos para introdução de um transgene no genoma de uma célula de planta, para expressar o produto de um transgene em uma célula de planta, para deleção de uma sequência de gene de epsps a partir de um locus de gene epsps no genoma de uma célula de planta, e para modular expressão de um gene de epsps
|
US11235026B2
(en)
|
2007-09-27 |
2022-02-01 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modulating PD1
|
JP2011500082A
(ja)
|
2007-10-25 |
2011-01-06 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
標的組込みのための方法および組成物
|
JP2011518555A
(ja)
|
2008-04-14 |
2011-06-30 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
標的組込みのための線形ドナーコンストラクト
|
WO2009134409A2
(en)
|
2008-04-30 |
2009-11-05 |
Sanbio, Inc. |
Neural regenerating cells with alterations in dna methylation
|
JP2011521643A
(ja)
|
2008-05-28 |
2011-07-28 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
Dna結合ドメインおよび切断ドメインを連結するための組成物
|
JP5763530B2
(ja)
|
2008-06-10 |
2015-08-12 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
Bax−およびBak−欠損細胞株の生成のための方法および組成物
|
CA2734235C
(en)
|
2008-08-22 |
2019-03-26 |
Sangamo Biosciences, Inc. |
Methods and compositions for targeted single-stranded cleavage and targeted integration
|
CA2741119C
(en)
|
2008-10-29 |
2019-02-12 |
Sangamo Biosciences, Inc. |
Methods and compositions for inactivating glutamine synthetase gene expression
|
WO2010065123A1
(en)
|
2008-12-04 |
2010-06-10 |
Sangamo Biosciences, Inc. |
Genome editing in rats using zinc-finger nucleases
|
ES2654923T3
(es)
|
2008-12-17 |
2018-02-15 |
Dow Agrosciences Llc |
Integración dirigida en la localización Zp15
|
EP2393506B1
(en)
|
2009-02-04 |
2018-03-28 |
Sangamo Therapeutics, Inc. |
Methods and compositions for treating neuropathies
|
CA2755192C
(en)
|
2009-03-20 |
2018-09-11 |
Sangamo Biosciences, Inc. |
Modification of cxcr4 using engineered zinc finger proteins
|
WO2010117464A1
(en)
|
2009-04-09 |
2010-10-14 |
Sangamo Biosciences, Inc. |
Targeted integration into stem cells
|
US8772008B2
(en)
|
2009-05-18 |
2014-07-08 |
Sangamo Biosciences, Inc. |
Methods and compositions for increasing nuclease activity
|
EP2449135B1
(en)
|
2009-06-30 |
2016-01-06 |
Sangamo BioSciences, Inc. |
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells
|
JP5866283B2
(ja)
|
2009-07-28 |
2016-02-17 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
トリヌクレオチド反復疾患を治療するための方法および組成物
|
EP2462230B1
(en)
|
2009-08-03 |
2015-07-15 |
Recombinetics, Inc. |
Methods and compositions for targeted gene modification
|
NZ598053A
(en)
|
2009-08-11 |
2014-01-31 |
Sangamo Biosciences Inc |
Organisms homozygous for targeted modification
|
RU2568056C2
(ru)
|
2009-10-22 |
2015-11-10 |
ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи |
Конструируемые белки с цинковыми пальцами, направленные на гены растений, вовлеченные в биосинтез жирных кислот
|
US8956828B2
(en)
|
2009-11-10 |
2015-02-17 |
Sangamo Biosciences, Inc. |
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
|
AU2011207769B2
(en)
|
2010-01-22 |
2015-05-28 |
Corteva Agriscience Llc |
Targeted genomic alteration
|
FR2955480B1
(fr)
|
2010-01-26 |
2012-01-06 |
Christian Choux |
Dispositif d'osteosynthese de la paroi thoracique
|
CA2788560A1
(en)
|
2010-02-08 |
2011-08-11 |
Sangamo Biosciences, Inc. |
Engineered cleavage half-domains
|
CA2788850C
(en)
|
2010-02-09 |
2019-06-25 |
Sangamo Biosciences, Inc. |
Targeted genomic modification with partially single-stranded donor molecules
|
JP5952263B2
(ja)
|
2010-04-26 |
2016-07-13 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
ジンクフィンガーヌクレアーゼを使ったrosa遺伝子座のゲノム編集
|
LT2566972T
(lt)
|
2010-05-03 |
2020-03-10 |
Sangamo Therapeutics, Inc. |
Kompozicijos, skirtos cinko pirštu modulių susiejimui
|
CA2798988C
(en)
|
2010-05-17 |
2020-03-10 |
Sangamo Biosciences, Inc. |
Tal-effector (tale) dna-binding polypeptides and uses thereof
|
CA3157027A1
(en)
|
2010-07-21 |
2012-01-26 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modification of a t-cell receptor gene
|
EP2622090B1
(en)
|
2010-09-27 |
2019-06-19 |
Sangamo Therapeutics, Inc. |
Compositions for inhibiting viral entry into cells
|
EP2627665B1
(en)
|
2010-10-12 |
2015-12-16 |
The Children's Hospital Of Philadelphia |
Methods and compositions for treating hemophilia B
|
US9267123B2
(en)
*
|
2011-01-05 |
2016-02-23 |
Sangamo Biosciences, Inc. |
Methods and compositions for gene correction
|
WO2012139045A1
(en)
|
2011-04-08 |
2012-10-11 |
Gilead Biologics, Inc. |
Methods and compositions for normalization of tumor vasculature by inhibition of loxl2
|
AU2012286901B2
(en)
|
2011-07-25 |
2016-10-27 |
Sangamo Therapeutics, Inc. |
Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (CFTR) gene
|
JP6185916B2
(ja)
|
2011-09-21 |
2017-08-23 |
サンガモ セラピューティクス, インコーポレイテッド |
導入遺伝子発現を制御するための方法および組成物
|
BR112014008456A2
(pt)
*
|
2011-10-11 |
2017-04-11 |
Aliophtha Ag |
regulação da expressão de receptor mediante distribuição de fatores de transcrição artificiais
|
AU2012328682B2
(en)
|
2011-10-27 |
2017-09-21 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modification of the HPRT locus
|
AU2012340213B2
(en)
|
2011-11-16 |
2017-12-07 |
Sangamo Therapeutics, Inc. |
Modified DNA-binding proteins and uses thereof
|
CA2862309A1
(en)
|
2012-01-27 |
2013-08-01 |
Sanbio, Inc. |
Methods and compositions for modulating angiogenesis and vasculogenesis
|
KR102084539B1
(ko)
|
2012-02-29 |
2020-03-04 |
상가모 테라퓨틱스, 인코포레이티드 |
헌팅턴병을 치료하기 위한 방법 및 조성물
|
CN102634535B
(zh)
*
|
2012-04-12 |
2014-11-26 |
西北农林科技大学 |
一种基于锌指蛋白插入载体的随机锌指蛋白库的构建方法
|
UA115875C2
(uk)
|
2012-05-02 |
2018-01-10 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Рослина помідора зі зменшеною активністю малатдегідрогенази та спосіб її отримання
|
BR112014027813A2
(pt)
|
2012-05-07 |
2017-08-08 |
Dow Agrosciences Llc |
métodos e composições para integração de transgenes direcionada mediada por nuclease
|
EP3816281A1
(en)
|
2012-07-11 |
2021-05-05 |
Sangamo Therapeutics, Inc. |
Methods and compositions for the treatment of lysosomal storage diseases
|
US10648001B2
(en)
|
2012-07-11 |
2020-05-12 |
Sangamo Therapeutics, Inc. |
Method of treating mucopolysaccharidosis type I or II
|
US10883119B2
(en)
|
2012-07-11 |
2021-01-05 |
Sangamo Therapeutics, Inc. |
Methods and compositions for delivery of biologics
|
RS60838B1
(sr)
|
2012-08-29 |
2020-10-30 |
Sangamo Therapeutics Inc |
Postupci i kompozicije za tretman genskog stanja
|
JP6775953B2
(ja)
|
2012-09-07 |
2020-10-28 |
ダウ アグロサイエンシィズ エルエルシー |
Fad3性能座および標的化切断を誘導可能である対応する標的部位特異的結合タンパク質
|
UA118090C2
(uk)
|
2012-09-07 |
2018-11-26 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив
|
UA119135C2
(uk)
|
2012-09-07 |
2019-05-10 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб отримання трансгенної рослини
|
DK2906684T3
(da)
|
2012-10-10 |
2020-09-28 |
Sangamo Therapeutics Inc |
T-celle-modificerende forbindelser og anvendelser deraf
|
JP2016500254A
(ja)
|
2012-12-05 |
2016-01-12 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
代謝疾患の調節のための方法および組成物
|
KR20150096696A
(ko)
|
2012-12-13 |
2015-08-25 |
다우 아그로사이언시즈 엘엘씨 |
메이즈에서 특정 유전자좌로의 정밀 유전자 표적화
|
WO2014130955A1
(en)
|
2013-02-25 |
2014-08-28 |
Sangamo Biosciences, Inc. |
Methods and compositions for enhancing nuclease-mediated gene disruption
|
JP6346266B2
(ja)
|
2013-03-21 |
2018-06-20 |
サンガモ セラピューティクス, インコーポレイテッド |
操作されたジンクフィンガータンパク質ヌクレアーゼを使用するt細胞受容体遺伝子の標的化された破壊
|
WO2014165612A2
(en)
|
2013-04-05 |
2014-10-09 |
Dow Agrosciences Llc |
Methods and compositions for integration of an exogenous sequence within the genome of plants
|
EP2997146A4
(en)
|
2013-05-15 |
2017-04-26 |
Sangamo BioSciences, Inc. |
Methods and compositions for treatment of a genetic condition
|
WO2015031619A1
(en)
|
2013-08-28 |
2015-03-05 |
Sangamo Biosciences, Inc. |
Compositions for linking dna-binding domains and cleavage domains
|
EP3057432B1
(en)
|
2013-10-17 |
2018-11-21 |
Sangamo Therapeutics, Inc. |
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells
|
EP3058072B1
(en)
|
2013-10-17 |
2021-05-19 |
Sangamo Therapeutics, Inc. |
Delivery methods and compositions for nuclease-mediated genome engineering
|
AU2014341927B2
(en)
|
2013-11-04 |
2017-12-14 |
Corteva Agriscience Llc |
Optimal maize loci
|
WO2015066634A2
(en)
|
2013-11-04 |
2015-05-07 |
Dow Agrosciences Llc |
Optimal soybean loci
|
EP3065540B1
(en)
|
2013-11-04 |
2021-12-15 |
Corteva Agriscience LLC |
Optimal maize loci
|
NZ718117A
(en)
|
2013-11-04 |
2017-09-29 |
Dow Agrosciences Llc |
Optimal soybean loci
|
BR112016010175A2
(pt)
|
2013-11-11 |
2017-10-03 |
Sangamo Biosciences Inc |
Repressor genético, seus usos, e composição farmacêutica
|
PT3068881T
(pt)
|
2013-11-13 |
2019-05-31 |
Childrens Medical Center |
Regulação da expressão de genes mediada por nucleases
|
JP6535684B2
(ja)
|
2013-12-09 |
2019-06-26 |
サンガモ セラピューティクス, インコーポレイテッド |
ゲノム操作のための方法および組成物
|
EP3110454B1
(en)
|
2014-02-24 |
2020-11-18 |
Sangamo Therapeutics, Inc. |
Methods and compositions for nuclease-mediated targeted integration
|
JP6594891B2
(ja)
|
2014-03-18 |
2019-10-23 |
サンガモ セラピューティクス, インコーポレイテッド |
ジンクフィンガータンパク質発現を調節するための方法および組成物
|
WO2015164748A1
(en)
|
2014-04-24 |
2015-10-29 |
Sangamo Biosciences, Inc. |
Engineered transcription activator like effector (tale) proteins
|
NZ725542A
(en)
|
2014-05-08 |
2024-02-23 |
Sangamo Biosciences Inc |
Methods and compositions for treating huntington’s disease
|
US9574211B2
(en)
|
2014-05-13 |
2017-02-21 |
Sangamo Biosciences, Inc. |
Methods and compositions for prevention or treatment of a disease
|
EP3151846A4
(en)
|
2014-06-05 |
2017-12-27 |
Sangamo BioSciences, Inc. |
Methods and compositions for nuclease design
|
WO2016005449A1
(en)
|
2014-07-08 |
2016-01-14 |
Vib Vzw |
Means and methods to increase plant yield
|
BR112017000925B1
(pt)
|
2014-07-14 |
2023-10-10 |
Washington State University |
Método de reprodução de porcos, método para gerar um porco sem nenhuma célula espermatogônica funcional, método de produção de um macho receptor e método de produção de porcos
|
WO2016011381A1
(en)
|
2014-07-18 |
2016-01-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Reducing cxcr4 expression and/or function to enhance engraftment of hematopoietic stem cells
|
WO2016014794A1
(en)
|
2014-07-25 |
2016-01-28 |
Sangamo Biosciences, Inc. |
Methods and compositions for modulating nuclease-mediated genome engineering in hematopoietic stem cells
|
US9757420B2
(en)
|
2014-07-25 |
2017-09-12 |
Sangamo Therapeutics, Inc. |
Gene editing for HIV gene therapy
|
WO2016019144A2
(en)
|
2014-07-30 |
2016-02-04 |
Sangamo Biosciences, Inc. |
Gene correction of scid-related genes in hematopoietic stem and progenitor cells
|
CN113699113A
(zh)
|
2014-09-16 |
2021-11-26 |
桑格摩治疗股份有限公司 |
用于造血干细胞中核酸酶介导的基因组工程化和校正的方法和组合物
|
US10889834B2
(en)
|
2014-12-15 |
2021-01-12 |
Sangamo Therapeutics, Inc. |
Methods and compositions for enhancing targeted transgene integration
|
US20180002379A1
(en)
|
2015-01-21 |
2018-01-04 |
Sangamo Therapeutics, Inc. |
Methods and compositions for identification of highly specific nucleases
|
CA2981077A1
(en)
|
2015-04-03 |
2016-10-06 |
Dana-Farber Cancer Institute, Inc. |
Composition and methods of genome editing of b-cells
|
US10179918B2
(en)
|
2015-05-07 |
2019-01-15 |
Sangamo Therapeutics, Inc. |
Methods and compositions for increasing transgene activity
|
SG10202112057QA
(en)
|
2015-05-12 |
2021-12-30 |
Sangamo Therapeutics Inc |
Nuclease-mediated regulation of gene expression
|
US9957501B2
(en)
|
2015-06-18 |
2018-05-01 |
Sangamo Therapeutics, Inc. |
Nuclease-mediated regulation of gene expression
|
JP6954890B2
(ja)
|
2015-07-13 |
2021-10-27 |
サンガモ セラピューティクス, インコーポレイテッド |
ヌクレアーゼ媒介ゲノム遺伝子操作のための送達方法及び組成物
|
WO2017023570A1
(en)
|
2015-08-06 |
2017-02-09 |
The Curators Of The University Of Missouri |
Pathogen-resistant animals having modified cd163 genes
|
EA037993B1
(ru)
|
2015-09-23 |
2021-06-21 |
Сангамо Терапьютикс, Инк. |
Репрессоры htt и их применение
|
EP3380622A4
(en)
|
2015-11-23 |
2019-08-07 |
Sangamo Therapeutics, Inc. |
METHODS AND COMPOSITIONS FOR MODIFYING IMMUNITY
|
SG10202005640UA
(en)
|
2015-12-18 |
2020-07-29 |
Sangamo Therapeutics Inc |
Targeted disruption of the mhc cell receptor
|
US11352631B2
(en)
|
2015-12-18 |
2022-06-07 |
Sangamo Therapeutics, Inc. |
Targeted disruption of the T cell receptor
|
BR112018014288A2
(pt)
|
2016-01-15 |
2018-12-18 |
Univ Minnesota |
métodos e composições para o tratamento de doença neurológica
|
EP3411056A4
(en)
|
2016-02-02 |
2019-10-02 |
Sangamo Therapeutics, Inc. |
COMPOUNDS FOR NETWORKING DNA BINDING DOMAINS AND SPLITTING DOMAINS
|
US11421218B2
(en)
|
2016-03-23 |
2022-08-23 |
Dana-Farber Cancer Institute, Inc. |
Methods for enhancing the efficiency of gene editing
|
EP3484870B1
(en)
|
2016-07-13 |
2022-11-16 |
Vertex Pharmaceuticals Incorporated |
Methods, compositions and kits for increasing genome editing efficiency
|
CA3031818A1
(en)
|
2016-07-27 |
2018-02-01 |
Case Western Reserve University |
Compounds and methods of promoting myelination
|
US11193136B2
(en)
|
2016-08-09 |
2021-12-07 |
Vib Vzw |
Cellulose synthase inhibitors and mutant plants
|
EP3964573A1
(en)
|
2016-08-24 |
2022-03-09 |
Sangamo Therapeutics, Inc. |
Engineered target specific nucleases
|
RS62758B1
(sr)
|
2016-08-24 |
2022-01-31 |
Sangamo Therapeutics Inc |
Regulacija genske ekspresije korišćenjem inženjeringom nukleaza
|
CA3035534A1
(en)
|
2016-09-07 |
2018-03-15 |
Sangamo Therapeutics, Inc. |
Modulation of liver genes
|
US11072660B2
(en)
|
2016-10-03 |
2021-07-27 |
Juno Therapeutics, Inc. |
HPV-specific binding molecules
|
EP3757120B8
(en)
|
2016-10-04 |
2022-06-15 |
Precision Biosciences, Inc. |
Co-stimulatory domains for use in genetically-modified cells
|
KR20190060829A
(ko)
|
2016-10-20 |
2019-06-03 |
상가모 테라퓨틱스, 인코포레이티드 |
파브리병의 치료를 위한 방법 및 조성물
|
US11020492B2
(en)
|
2016-10-31 |
2021-06-01 |
Sangamo Therapeutics, Inc. |
Gene correction of SCID-related genes in hematopoietic stem and progenitor cells
|
US11504389B2
(en)
|
2016-12-01 |
2022-11-22 |
Sangamo Therapeutics, Inc. |
Tau modulators and methods and compositions for delivery thereof
|
ES2968892T3
(es)
|
2016-12-08 |
2024-05-14 |
Univ Case Western Reserve |
Métodos y composiciones para aumentar la producción de mielina funcional
|
WO2018195418A1
(en)
|
2017-04-20 |
2018-10-25 |
Oregon Health & Science University |
Human gene correction
|
RU2019139045A
(ru)
|
2017-05-03 |
2021-06-03 |
Сангамо Терапьютикс, Инк. |
Способы и композиции для модификации гена регулятора трансмембранной проводимости при кистозном фиброзе (cftr)
|
EP4029943A1
(en)
|
2017-05-08 |
2022-07-20 |
Precision Biosciences, Inc. |
Nucleic acid molecules encoding an engineered antigen receptor and an inhibitory nucleic acid molecule and methods of use thereof
|
US11512287B2
(en)
|
2017-06-16 |
2022-11-29 |
Sangamo Therapeutics, Inc. |
Targeted disruption of T cell and/or HLA receptors
|
JP2020529834A
(ja)
|
2017-06-30 |
2020-10-15 |
プレシジョン バイオサイエンシズ,インク. |
T細胞受容体アルファ遺伝子の改変されたイントロンを含む遺伝子改変t細胞
|
JP2020537515A
(ja)
|
2017-10-03 |
2020-12-24 |
ジュノー セラピューティクス インコーポレイテッド |
Hpv特異的結合分子
|
EP4269560A3
(en)
|
2017-10-03 |
2024-01-17 |
Precision Biosciences, Inc. |
Modified epidermal growth factor receptor peptides for use in genetically-modified cells
|
EP3704238B1
(en)
|
2017-11-01 |
2024-01-03 |
Precision Biosciences, Inc. |
Engineered nucleases that target human and canine factor viii genes as a treatment for hemophilia a
|
KR20200079539A
(ko)
|
2017-11-09 |
2020-07-03 |
상가모 테라퓨틱스, 인코포레이티드 |
시토카인 유도성 sh2-함유 단백질 (cish) 유전자의 유전자 변형
|
EA202091709A1
(ru)
|
2018-01-17 |
2020-11-10 |
Вертекс Фармасьютикалз Инкорпорейтед |
Ингибиторы днк-пк
|
MA51619A
(fr)
|
2018-01-17 |
2021-04-14 |
Vertex Pharma |
Inhibiteurs de la protéine kinase dépendante de l'adn
|
MA51623A
(fr)
|
2018-01-17 |
2021-04-14 |
Vertex Pharma |
Composés de quinoxalinone, compositions, procédés et kits pour augmenter l'efficacité d'édition du génome
|
WO2019157324A1
(en)
|
2018-02-08 |
2019-08-15 |
Sangamo Therapeutics, Inc. |
Engineered target specific nucleases
|
CN112566698A
(zh)
|
2018-04-05 |
2021-03-26 |
朱诺治疗学股份有限公司 |
T细胞受体和表达该t细胞受体的工程化细胞
|
JP2021520211A
(ja)
|
2018-04-05 |
2021-08-19 |
ジュノー セラピューティクス インコーポレイテッド |
組換え受容体を発現するt細胞、関連ポリヌクレオチド、および方法
|
MA52656A
(fr)
|
2018-04-05 |
2021-02-17 |
Editas Medicine Inc |
Procédés de production de cellules exprimant un récepteur recombinant et compositions associées
|
CN112313246A
(zh)
|
2018-04-18 |
2021-02-02 |
桑格摩生物治疗股份有限公司 |
用于调节亨廷顿蛋白(htt)的锌指蛋白组合物
|
US11690921B2
(en)
|
2018-05-18 |
2023-07-04 |
Sangamo Therapeutics, Inc. |
Delivery of target specific nucleases
|
AU2019326408A1
(en)
|
2018-08-23 |
2021-03-11 |
Sangamo Therapeutics, Inc. |
Engineered target specific base editors
|
EP4234570A3
(en)
|
2018-09-18 |
2023-12-13 |
Sangamo Therapeutics, Inc. |
Programmed cell death 1 (pd1) specific nucleases
|
EP3898661A1
(en)
|
2018-12-21 |
2021-10-27 |
Precision BioSciences, Inc. |
Genetic modification of the hydroxyacid oxidase 1 gene for treatment of primary hyperoxaluria
|
AU2020205717A1
(en)
|
2019-01-11 |
2021-08-12 |
Acuitas Therapeutics, Inc. |
Lipids for lipid nanoparticle delivery of active agents
|
CN112805026A
(zh)
|
2019-02-06 |
2021-05-14 |
桑格摩生物治疗股份有限公司 |
用于治疗i型黏多糖贮积症的方法
|
BR112021019448A2
(pt)
|
2019-04-02 |
2021-11-30 |
Sangamo Therapeutics Inc |
Métodos para o tratamento de beta-talassemia
|
MX2021012110A
(es)
|
2019-04-03 |
2022-01-06 |
Prec Biosciences Inc |
Celulas inmunitarias geneticamente modificadas que comprenden un arnhc adaptado a microarn (arnhcmir).
|
EP3947646A1
(en)
|
2019-04-05 |
2022-02-09 |
Precision BioSciences, Inc. |
Methods of preparing populations of genetically-modified immune cells
|
WO2020219726A1
(en)
|
2019-04-23 |
2020-10-29 |
Sangamo Therapeutics, Inc. |
Modulators of chromosome 9 open reading frame 72 gene expression and uses thereof
|
US20220184131A1
(en)
|
2019-05-01 |
2022-06-16 |
Juno Therapeutics, Inc. |
Cells expressing a recombinant receptor from a modified tgfbr2 locus, related polynucleotides and methods
|
KR20220016474A
(ko)
|
2019-05-01 |
2022-02-09 |
주노 쎄러퓨티크스 인코퍼레이티드 |
변형된 cd247 유전자 자리로부터 키메라 수용체를 발현하는 세포, 관련 폴리뉴클레오타이드 및 방법
|
US20220273715A1
(en)
|
2019-07-25 |
2022-09-01 |
Precision Biosciences, Inc. |
Compositions and methods for sequential stacking of nucleic acid sequences into a genomic locus
|
JP2022544825A
(ja)
|
2019-08-20 |
2022-10-21 |
プレシジョン バイオサイエンシズ,インク. |
細胞免疫療法のためのリンパ球枯渇投与レジメン
|
WO2021035170A1
(en)
|
2019-08-21 |
2021-02-25 |
Precision Biosciences, Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
JP2022551286A
(ja)
|
2019-10-02 |
2022-12-08 |
サンガモ セラピューティクス, インコーポレイテッド |
α-シヌクレイン発現を抑制するためのジンクフィンガータンパク質転写因子
|
CN114728037A
(zh)
|
2019-10-02 |
2022-07-08 |
桑格摩生物治疗股份有限公司 |
用于朊病毒病治疗的锌指蛋白转录因子
|
WO2021087305A1
(en)
|
2019-10-30 |
2021-05-06 |
Precision Biosciences, Inc. |
Cd20 chimeric antigen receptors and methods of use for immunotherapy
|
TW202132565A
(zh)
|
2019-11-01 |
2021-09-01 |
美商聖加莫治療股份有限公司 |
Gin重組酶變異體
|
CA3160096A1
(en)
|
2019-12-06 |
2021-06-10 |
Bruce J. Mccreedy Jr. |
Methods for cancer immunotherapy
|
AR121118A1
(es)
|
2020-01-22 |
2022-04-20 |
Sangamo Therapeutics Inc |
Factores de transcripción de proteínas de dedos de zinc para reprimir la expresión de tau
|
WO2021158915A1
(en)
|
2020-02-06 |
2021-08-12 |
Precision Biosciences, Inc. |
Recombinant adeno-associated virus compositions and methods for producing and using the same
|
WO2021202513A1
(en)
|
2020-03-31 |
2021-10-07 |
Elo Life Systems |
Modulation of endogenous mogroside pathway genes in watermelon and other cucurbits
|
WO2021224416A1
(en)
|
2020-05-06 |
2021-11-11 |
Cellectis S.A. |
Methods to genetically modify cells for delivery of therapeutic proteins
|
US20230212613A1
(en)
|
2020-05-06 |
2023-07-06 |
Cellectis S.A. |
Methods for targeted insertion of exogenous sequences in cellular genomes
|
US20230183664A1
(en)
|
2020-05-11 |
2023-06-15 |
Precision Biosciences, Inc. |
Self-limiting viral vectors encoding nucleases
|
US20230181641A1
(en)
|
2020-05-13 |
2023-06-15 |
Juno Therapeutics, Inc. |
Process for producing donor-batched cells expressing a recombinant receptor
|
JP2023531531A
(ja)
|
2020-06-26 |
2023-07-24 |
ジュノ セラピューティクス ゲーエムベーハー |
組換え受容体を条件付きで発現する操作されたt細胞、関連ポリヌクレオチド、および方法
|
US11976019B2
(en)
|
2020-07-16 |
2024-05-07 |
Acuitas Therapeutics, Inc. |
Cationic lipids for use in lipid nanoparticles
|
EP4192875A1
(en)
|
2020-08-10 |
2023-06-14 |
Precision BioSciences, Inc. |
Antibodies and fragments specific for b-cell maturation antigen and uses thereof
|
WO2022046760A2
(en)
|
2020-08-25 |
2022-03-03 |
Kite Pharma, Inc. |
T cells with improved functionality
|
JP2023542705A
(ja)
|
2020-09-25 |
2023-10-11 |
サンガモ セラピューティクス, インコーポレイテッド |
核酸塩基編集のためのジンクフィンガー融合タンパク質
|
US20230365995A1
(en)
|
2020-10-07 |
2023-11-16 |
Precision Biosciences, Inc. |
Lipid nanoparticle compositions
|
WO2022087527A1
(en)
|
2020-10-23 |
2022-04-28 |
Elo Life Systems, Inc. |
Methods for producing vanilla plants with improved flavor and agronomic production
|
EP4240756A1
(en)
|
2020-11-04 |
2023-09-13 |
Juno Therapeutics, Inc. |
Cells expressing a chimeric receptor from a modified invariant cd3 immunoglobulin superfamily chain locus and related polynucleotides and methods
|
US20240000051A1
(en)
|
2020-11-16 |
2024-01-04 |
Pig Improvement Company Uk Limited |
Influenza a-resistant animals having edited anp32 genes
|
WO2022165111A1
(en)
|
2021-01-28 |
2022-08-04 |
Precision Biosciences, Inc. |
Modulation of tgf beta signaling in genetically-modified eukaryotic cells
|
US20240141311A1
(en)
|
2021-04-22 |
2024-05-02 |
North Carolina State University |
Compositions and methods for generating male sterile plants
|
WO2023064872A1
(en)
|
2021-10-14 |
2023-04-20 |
Precision Biosciences, Inc. |
Combinations of anti-bcma car t cells and gamma secretase inhibitors
|
WO2023070003A1
(en)
|
2021-10-19 |
2023-04-27 |
Precision Biosciences, Inc. |
Gene editing methods for treating alpha-1 antitrypsin (aat) deficiency
|
WO2023081900A1
(en)
|
2021-11-08 |
2023-05-11 |
Juno Therapeutics, Inc. |
Engineered t cells expressing a recombinant t cell receptor (tcr) and related systems and methods
|
WO2023091910A1
(en)
|
2021-11-16 |
2023-05-25 |
Precision Biosciences, Inc. |
Methods for cancer immunotherapy
|
WO2023105244A1
(en)
|
2021-12-10 |
2023-06-15 |
Pig Improvement Company Uk Limited |
Editing tmprss2/4 for disease resistance in livestock
|
WO2023122722A1
(en)
|
2021-12-22 |
2023-06-29 |
Sangamo Therapeutics, Inc. |
Novel zinc finger fusion proteins for nucleobase editing
|
WO2023131616A1
(en)
|
2022-01-05 |
2023-07-13 |
Vib Vzw |
Means and methods to increase abiotic stress tolerance in plants
|
WO2023131637A1
(en)
|
2022-01-06 |
2023-07-13 |
Vib Vzw |
Improved silage grasses
|
WO2023144199A1
(en)
|
2022-01-26 |
2023-08-03 |
Vib Vzw |
Plants having reduced levels of bitter taste metabolites
|
WO2024013514A2
(en)
|
2022-07-15 |
2024-01-18 |
Pig Improvement Company Uk Limited |
Gene edited livestock animals having coronavirus resistance
|
WO2024100604A1
(en)
|
2022-11-09 |
2024-05-16 |
Juno Therapeutics Gmbh |
Methods for manufacturing engineered immune cells
|