US7901693B2
(en)
|
1998-09-30 |
2011-03-08 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
US7329410B1
(en)
|
1998-09-30 |
2008-02-12 |
Corixa Corporation |
Compositions and method for WT1 specific immunotherapy
|
US7115272B1
(en)
|
1998-09-30 |
2006-10-03 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
US7655249B2
(en)
|
1998-09-30 |
2010-02-02 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
US7144581B2
(en)
|
2000-10-09 |
2006-12-05 |
Corixa Corporation |
Compositions and methods for WT1 specific immunotherapy
|
US7063854B1
(en)
|
1998-09-30 |
2006-06-20 |
Corixa Corporation |
Composition and methods for WTI specific immunotherapy
|
US7029847B2
(en)
|
2000-05-16 |
2006-04-18 |
Massachusetts Institute Of Technology |
Methods and compositions for interaction trap assays
|
AU2001263155A1
(en)
*
|
2000-05-16 |
2001-11-26 |
Massachusetts Institute Of Technology |
Methods and compositions for interaction trap assays
|
AU2002225187A1
(en)
*
|
2001-01-22 |
2002-07-30 |
Sangamo Biosciences, Inc. |
Zinc finger polypeptides and their use
|
WO2003016571A1
(en)
*
|
2001-08-17 |
2003-02-27 |
Toolgen, Inc. |
Zinc finger domain libraries
|
US7553494B2
(en)
|
2001-08-24 |
2009-06-30 |
Corixa Corporation |
WT1 fusion proteins
|
CN100463962C
(zh)
*
|
2001-12-07 |
2009-02-25 |
图尔金株式会社 |
嵌合蛋白质的表型筛选
|
US8799501B2
(en)
*
|
2002-04-30 |
2014-08-05 |
Hewlett-Packard Development Company, L. P. |
System and method for anonymously sharing and scoring information pointers, within a system for harvesting community knowledge
|
US20070020627A1
(en)
*
|
2002-06-11 |
2007-01-25 |
The Scripps Research Institute |
Artificial transcription factors
|
AU2003260973A1
(en)
*
|
2002-09-05 |
2004-03-29 |
Toolgen, Inc. |
Bioinformatics analysis of cellular effects of artificial transcription factors
|
US20060251643A1
(en)
*
|
2002-12-09 |
2006-11-09 |
Toolgen, Inc. |
Regulatory zinc finger proteins
|
CN1836048A
(zh)
*
|
2003-06-10 |
2006-09-20 |
图尔金株式会社 |
可转导的dna结合蛋白
|
JP4555292B2
(ja)
|
2003-08-08 |
2010-09-29 |
サンガモ バイオサイエンシズ インコーポレイテッド |
標的化された切断及び組換えの方法及び組成物
|
US7888121B2
(en)
|
2003-08-08 |
2011-02-15 |
Sangamo Biosciences, Inc. |
Methods and compositions for targeted cleavage and recombination
|
US20120196370A1
(en)
|
2010-12-03 |
2012-08-02 |
Fyodor Urnov |
Methods and compositions for targeted genomic deletion
|
WO2005028630A2
(en)
|
2003-09-19 |
2005-03-31 |
Sangamo Biosciences, Inc. |
Engineered zinc finger proteins for regulation of gene expression
|
US20070042378A1
(en)
*
|
2003-12-23 |
2007-02-22 |
Kim Jin-Soo |
Regulation of prokaryotic gene expression with zinc finger proteins
|
AU2005232665B2
(en)
*
|
2004-04-08 |
2010-05-13 |
Sangamo Therapeutics, Inc. |
Methods and compositions for treating neuropathic and neurodegenerative conditions
|
KR100857125B1
(ko)
|
2004-05-25 |
2008-09-11 |
주식회사 툴젠 |
단일클론 항체 생산을 증가시키는 폴리펩타이드, 이를코드하는 핵산 및 이의 용도
|
US20060063231A1
(en)
|
2004-09-16 |
2006-03-23 |
Sangamo Biosciences, Inc. |
Compositions and methods for protein production
|
EP1913149A4
(de)
|
2005-07-26 |
2009-08-05 |
Sangamo Biosciences Inc |
Gezielte integration und expression exogener nukleinsäuresequenzen
|
ES2465996T3
(es)
|
2006-05-25 |
2014-06-09 |
Sangamo Biosciences, Inc. |
Métodos y composiciones para la inactivación genética
|
EP2213731B1
(de)
|
2006-05-25 |
2013-12-04 |
Sangamo BioSciences, Inc. |
Varianten von Foki Spaltungs-Halbdomänen
|
UA106193C2
(ru)
|
2006-08-11 |
2014-08-11 |
ДАУ АГРОСАЙЕНСИЗ ЕлЕлСи |
Гомологичная рекомбинация, опосредованная нуклеазами с цинковыми пальцами
|
KR100812110B1
(ko)
*
|
2006-10-24 |
2008-03-12 |
한국과학기술원 |
징크 핑거 단백질과 원핵 생물의 전사 인자를 포함하는인공 전사 인자의 제조 및 이의 이용
|
US9217026B2
(en)
|
2006-11-13 |
2015-12-22 |
Sangamo Biosciences, Inc. |
Method of inactivating a glucocorticoid receptor gene in an isolated cell
|
BRPI0720048A8
(pt)
|
2006-12-14 |
2023-02-07 |
Dow Agrosciences Llc |
Proteínas de dedo de zinco não-canônicas otimizadas
|
EP2137310B1
(de)
|
2007-04-26 |
2010-11-24 |
Sangamo BioSciences, Inc. |
Gezielte integration in die ppp1r12c-position
|
EP2527435B2
(de)
|
2007-07-12 |
2021-10-13 |
Sangamo BioSciences, Inc. |
Verfahren und Zusammensetzung zur Deaktivierung der Alpha-1,6-fucosyltransferase-genexpression
|
BRPI0817560B1
(pt)
|
2007-09-27 |
2022-09-20 |
Dow Agrosciences Llc |
Proteínas de dedo de zinco (zfp) engenheiradas que têm como alvo genes de 5-enolpiruvil shiquimato-3-fosfato sintase, nuclease de dedo de zinco (zfn), vetor, bem como métodos para introdução de um transgene no genoma de uma célula de planta, para expressar o produto de um transgene em uma célula de planta, para deleção de uma sequência de gene de epsps a partir de um locus de gene epsps no genoma de uma célula de planta, e para modular expressão de um gene de epsps
|
US8563314B2
(en)
|
2007-09-27 |
2013-10-22 |
Sangamo Biosciences, Inc. |
Methods and compositions for modulating PD1
|
US11235026B2
(en)
|
2007-09-27 |
2022-02-01 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modulating PD1
|
WO2009042163A2
(en)
|
2007-09-27 |
2009-04-02 |
Sangamo Biosciences, Inc. |
Rapid in vivo identification of biologically active nucleases
|
JP2011500082A
(ja)
|
2007-10-25 |
2011-01-06 |
サンガモ バイオサイエンシーズ, インコーポレイテッド |
標的組込みのための方法および組成物
|
EP2281050B1
(de)
|
2008-04-14 |
2014-04-02 |
Sangamo BioSciences, Inc. |
Lineare donorkonstrukte zur gezielten integration
|
ES2594229T3
(es)
|
2008-04-30 |
2016-12-16 |
Sanbio, Inc. |
Células de regeneración nerviosa con alteraciones en la metilación del ADN
|
WO2009154686A1
(en)
|
2008-05-28 |
2009-12-23 |
Sangamo Biosciences, Inc. |
Compositions for linking dna-binding domains and cleavage domains
|
KR101802393B1
(ko)
|
2008-06-10 |
2017-11-28 |
상가모 테라퓨틱스, 인코포레이티드 |
Bax- 및 bak-결함 세포주들의 제조 방법 및 조성물
|
CN102159722B
(zh)
|
2008-08-22 |
2014-09-03 |
桑格摩生物科学股份有限公司 |
用于靶向单链切割和靶向整合的方法和组合物
|
EP2344660B1
(de)
|
2008-10-29 |
2018-01-17 |
Sangamo Therapeutics, Inc. |
Verfahren und zusammensetzungen zur inaktivierung einer glutaminsynthetase-genexpression
|
WO2010065123A1
(en)
|
2008-12-04 |
2010-06-10 |
Sangamo Biosciences, Inc. |
Genome editing in rats using zinc-finger nucleases
|
EP2370575B1
(de)
|
2008-12-17 |
2017-11-01 |
Dow AgroSciences LLC |
Gezielte integration in die zp15-position
|
CA2934285C
(en)
|
2009-02-04 |
2018-11-27 |
Sangamo Biosciences, Inc. |
Methods and compositions for treating neuropathies
|
CA2755192C
(en)
|
2009-03-20 |
2018-09-11 |
Sangamo Biosciences, Inc. |
Modification of cxcr4 using engineered zinc finger proteins
|
WO2010117464A1
(en)
|
2009-04-09 |
2010-10-14 |
Sangamo Biosciences, Inc. |
Targeted integration into stem cells
|
US8772008B2
(en)
|
2009-05-18 |
2014-07-08 |
Sangamo Biosciences, Inc. |
Methods and compositions for increasing nuclease activity
|
WO2011002503A1
(en)
|
2009-06-30 |
2011-01-06 |
Sangamo Biosciences, Inc. |
Rapid screening of biologically active nucleases and isolation of nuclease-modified cells
|
US9234016B2
(en)
|
2009-07-28 |
2016-01-12 |
Sangamo Biosciences, Inc. |
Engineered zinc finger proteins for treating trinucleotide repeat disorders
|
NZ598457A
(en)
|
2009-08-03 |
2014-06-27 |
Recombinetics Inc |
Methods and compositions for targeted gene modification
|
NZ619886A
(en)
|
2009-08-11 |
2015-03-27 |
Sangamo Biosciences Inc |
Organisms homozygous for targeted modification
|
US8592645B2
(en)
|
2009-10-22 |
2013-11-26 |
Dow Agrosciences Llc |
Engineered zinc finger proteins targeting plant genes involved in fatty acid biosynthesis
|
US8956828B2
(en)
|
2009-11-10 |
2015-02-17 |
Sangamo Biosciences, Inc. |
Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases
|
CA2787494C
(en)
|
2010-01-22 |
2019-09-17 |
Dow Agrosciences Llc |
Targeted genomic alteration
|
FR2955480B1
(fr)
|
2010-01-26 |
2012-01-06 |
Christian Choux |
Dispositif d'osteosynthese de la paroi thoracique
|
PT2534173T
(pt)
|
2010-02-08 |
2019-10-31 |
Sangamo Therapeutics Inc |
Semidomínios de clivagem manipulados
|
WO2011100058A1
(en)
|
2010-02-09 |
2011-08-18 |
Sangamo Biosciences, Inc. |
Targeted genomic modification with partially single-stranded donor molecules
|
CA2796600C
(en)
|
2010-04-26 |
2019-08-13 |
Sangamo Biosciences, Inc. |
Genome editing of a rosa locus using zinc-finger nucleases
|
LT2566972T
(lt)
|
2010-05-03 |
2020-03-10 |
Sangamo Therapeutics, Inc. |
Kompozicijos, skirtos cinko pirštu modulių susiejimui
|
JP6208580B2
(ja)
|
2010-05-17 |
2017-10-04 |
サンガモ セラピューティクス, インコーポレイテッド |
新規のdna結合タンパク質及びその使用
|
EP2596011B1
(de)
|
2010-07-21 |
2018-10-03 |
Sangamo Therapeutics, Inc. |
Verfahren und zusammensetzungen zur veränderung eines hla-locus
|
EP2622090B1
(de)
|
2010-09-27 |
2019-06-19 |
Sangamo Therapeutics, Inc. |
Zusammensetzungen zur hemmung des eindringens von viren in zellen
|
KR101930711B1
(ko)
|
2010-10-12 |
2018-12-19 |
더 칠드런스 호스피탈 오브 필라델피아 |
혈우병 b의 치료를 위한 방법 및 조성물
|
WO2012094132A1
(en)
|
2011-01-05 |
2012-07-12 |
Sangamo Biosciences, Inc. |
Methods and compositions for gene correction
|
EP2694554A1
(de)
|
2011-04-08 |
2014-02-12 |
Gilead Biologics, Inc. |
Verfahren und zusammensetzungen zur normalisierung einer tumorvaskulatur mittels loxl2-hemmung
|
AU2012286901B2
(en)
|
2011-07-25 |
2016-10-27 |
Sangamo Therapeutics, Inc. |
Methods and compositions for alteration of a cystic fibrosis transmembrane conductance regulator (CFTR) gene
|
SG11201400707TA
(en)
|
2011-09-21 |
2014-04-28 |
Sangamo Biosciences Inc |
Methods and compositions for regulation of transgene expression
|
EA201490531A1
(ru)
*
|
2011-10-11 |
2014-08-29 |
Алиофта Аг |
Регуляция экспрессии рецептора посредством доставки искусственных факторов транскрипции
|
WO2013063315A2
(en)
|
2011-10-27 |
2013-05-02 |
Sangamo Biosciences, Inc. |
Methods and compositions for modification of the hprt locus
|
AU2012340213B2
(en)
|
2011-11-16 |
2017-12-07 |
Sangamo Therapeutics, Inc. |
Modified DNA-binding proteins and uses thereof
|
CN112386681A
(zh)
|
2012-01-27 |
2021-02-23 |
桑比欧公司 |
用于调节血管生成和血管发生的方法和组合物
|
WO2013130824A1
(en)
|
2012-02-29 |
2013-09-06 |
Sangamo Biosciences, Inc. |
Methods and compositions for treating huntington's disease
|
CN102634535B
(zh)
*
|
2012-04-12 |
2014-11-26 |
西北农林科技大学 |
一种基于锌指蛋白插入载体的随机锌指蛋白库的构建方法
|
BR112014027227B1
(pt)
|
2012-05-02 |
2022-04-19 |
Sangamo Biosciences, Inc. |
Métodos para produzir uma planta que apresenta expressão reduzida do gene endógeno de malato desidrogenase (mdh), e para aumentar o rendimento da cultura
|
AU2013259647B2
(en)
|
2012-05-07 |
2018-11-08 |
Corteva Agriscience Llc |
Methods and compositions for nuclease-mediated targeted integration of transgenes
|
ES2697912T3
(es)
|
2012-07-11 |
2019-01-29 |
Sangamo Therapeutics Inc |
Métodos y composiciones para el tratamiento de enfermedades monogénicas
|
WO2014011901A2
(en)
|
2012-07-11 |
2014-01-16 |
Sangamo Biosciences, Inc. |
Methods and compositions for delivery of biologics
|
US10648001B2
(en)
|
2012-07-11 |
2020-05-12 |
Sangamo Therapeutics, Inc. |
Method of treating mucopolysaccharidosis type I or II
|
KR20220164090A
(ko)
|
2012-08-29 |
2022-12-12 |
상가모 테라퓨틱스, 인코포레이티드 |
유전적 병태를 치료하기 위한 방법 및 조성물
|
UA119135C2
(uk)
|
2012-09-07 |
2019-05-10 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб отримання трансгенної рослини
|
RU2665811C2
(ru)
|
2012-09-07 |
2018-09-04 |
ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи |
Локусы fad3 для выполнения операций и соответствующие связывающиеся со специфическими сайтами-мишенями белки, способные к вызову направленных разрывов
|
UA118090C2
(uk)
|
2012-09-07 |
2018-11-26 |
ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі |
Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив
|
US9597357B2
(en)
|
2012-10-10 |
2017-03-21 |
Sangamo Biosciences, Inc. |
T cell modifying compounds and uses thereof
|
US9255250B2
(en)
|
2012-12-05 |
2016-02-09 |
Sangamo Bioscience, Inc. |
Isolated mouse or human cell having an exogenous transgene in an endogenous albumin gene
|
US20140173783A1
(en)
|
2012-12-13 |
2014-06-19 |
Dow Agrosciences Llc |
Precision gene targeting to a particular locus in maize
|
WO2014130955A1
(en)
|
2013-02-25 |
2014-08-28 |
Sangamo Biosciences, Inc. |
Methods and compositions for enhancing nuclease-mediated gene disruption
|
CN105208866B
(zh)
|
2013-03-21 |
2018-11-23 |
桑格摩生物治疗股份有限公司 |
使用工程化锌指蛋白核酸酶靶向断裂t细胞受体基因
|
AU2014248208C1
(en)
|
2013-04-05 |
2023-04-27 |
Corteva Agriscience Llc |
Methods and compositions for integration of an exogenous sequence within the genome of plants
|
EP2997146A4
(de)
|
2013-05-15 |
2017-04-26 |
Sangamo BioSciences, Inc. |
Verfahren und zusammensetzungen zur behandlung eines genetischen leidens
|
EP3039136B8
(de)
|
2013-08-28 |
2020-12-16 |
Sangamo Therapeutics, Inc. |
Zusammensetzungen zur vernetzung von dna-bindungsdomänen und -spaltungsdomänen
|
US10117899B2
(en)
|
2013-10-17 |
2018-11-06 |
Sangamo Therapeutics, Inc. |
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells
|
US9957526B2
(en)
|
2013-10-17 |
2018-05-01 |
Sangamo Therapeutics, Inc. |
Delivery methods and compositions for nuclease-mediated genome engineering
|
AP2016009227A0
(en)
|
2013-11-04 |
2016-05-31 |
Dow Agrosciences Llc |
Optimal maize loci
|
US9909131B2
(en)
|
2013-11-04 |
2018-03-06 |
Dow Agrosciences Llc |
Optimal soybean loci
|
CN107223156A
(zh)
|
2013-11-04 |
2017-09-29 |
美国陶氏益农公司 |
最优玉米座位
|
CA2926822C
(en)
|
2013-11-04 |
2022-12-13 |
Dow Agrosciences Llc |
Optimal soybean loci
|
WO2015070212A1
(en)
|
2013-11-11 |
2015-05-14 |
Sangamo Biosciences, Inc. |
Methods and compositions for treating huntington's disease
|
HRP20211706T1
(hr)
|
2013-11-13 |
2022-02-04 |
The Children's Medical Center Corporation |
Nukleazom posredovana regulacija ekspresije gena
|
US9771403B2
(en)
|
2013-12-09 |
2017-09-26 |
Sangamo Therapeutics, Inc. |
Methods and compositions for treating hemophilia
|
JP6606088B2
(ja)
|
2014-02-24 |
2019-11-13 |
サンガモ セラピューティクス, インコーポレイテッド |
ヌクレアーゼ媒介性標的化組み込みのための方法および組成物
|
CN106459894B
(zh)
|
2014-03-18 |
2020-02-18 |
桑格摩生物科学股份有限公司 |
用于调控锌指蛋白表达的方法和组合物
|
WO2015164748A1
(en)
|
2014-04-24 |
2015-10-29 |
Sangamo Biosciences, Inc. |
Engineered transcription activator like effector (tale) proteins
|
RU2691102C2
(ru)
|
2014-05-08 |
2019-06-11 |
Сангамо Байосайенсиз, Инк. |
Способы и композиции для лечения болезни хантингтона
|
WO2015175642A2
(en)
|
2014-05-13 |
2015-11-19 |
Sangamo Biosciences, Inc. |
Methods and compositions for prevention or treatment of a disease
|
EP3152319A4
(de)
|
2014-06-05 |
2017-12-27 |
Sangamo BioSciences, Inc. |
Verfahren und zusammensetzungen zur nukleasekonstruktion
|
US20170159065A1
(en)
|
2014-07-08 |
2017-06-08 |
Vib Vzw |
Means and methods to increase plant yield
|
FI3169778T3
(fi)
|
2014-07-14 |
2023-12-13 |
Univ Washington State |
Ituradan soluja ablatoiva nanos-geeninpoisto
|
WO2016011381A1
(en)
|
2014-07-18 |
2016-01-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Reducing cxcr4 expression and/or function to enhance engraftment of hematopoietic stem cells
|
WO2016014837A1
(en)
|
2014-07-25 |
2016-01-28 |
Sangamo Biosciences, Inc. |
Gene editing for hiv gene therapy
|
US9816074B2
(en)
|
2014-07-25 |
2017-11-14 |
Sangamo Therapeutics, Inc. |
Methods and compositions for modulating nuclease-mediated genome engineering in hematopoietic stem cells
|
WO2016019144A2
(en)
|
2014-07-30 |
2016-02-04 |
Sangamo Biosciences, Inc. |
Gene correction of scid-related genes in hematopoietic stem and progenitor cells
|
RS62334B1
(sr)
|
2014-09-16 |
2021-10-29 |
Sangamo Therapeutics Inc |
Postupci i sastavi za inženjering genoma posredovan nukleazom i korekciju kod matičnih ćelija hematopoeze
|
US10889834B2
(en)
|
2014-12-15 |
2021-01-12 |
Sangamo Therapeutics, Inc. |
Methods and compositions for enhancing targeted transgene integration
|
EP3247366A4
(de)
|
2015-01-21 |
2018-10-31 |
Sangamo Therapeutics, Inc. |
Verfahren und zusammensetzungen zur identifizierung hochspezifischer nukleasen
|
EP4335918A3
(de)
|
2015-04-03 |
2024-04-17 |
Dana-Farber Cancer Institute, Inc. |
Zusammensetzung und verfahren zur genomeditierung von b-zellen
|
US10179918B2
(en)
|
2015-05-07 |
2019-01-15 |
Sangamo Therapeutics, Inc. |
Methods and compositions for increasing transgene activity
|
CA2984013A1
(en)
|
2015-05-12 |
2016-11-17 |
Sangamo Therapeutics, Inc. |
Nuclease-mediated regulation of gene expression
|
US9957501B2
(en)
|
2015-06-18 |
2018-05-01 |
Sangamo Therapeutics, Inc. |
Nuclease-mediated regulation of gene expression
|
WO2017011519A1
(en)
|
2015-07-13 |
2017-01-19 |
Sangamo Biosciences, Inc. |
Delivery methods and compositions for nuclease-mediated genome engineering
|
EP3331355B1
(de)
|
2015-08-06 |
2024-04-03 |
The Curators of the University of Missouri |
Gegen das reproduktive und respiratorische schweinesyndromvirus (prrsv) resistente schweine und zellen mit modifizierten cd163-genen
|
KR20180054672A
(ko)
|
2015-09-23 |
2018-05-24 |
상가모 테라퓨틱스, 인코포레이티드 |
Htt 리프레서 및 이의 용도
|
AU2016361350B2
(en)
|
2015-11-23 |
2023-04-06 |
Sangamo Therapeutics, Inc. |
Methods and compositions for engineering immunity
|
JP2018537112A
(ja)
|
2015-12-18 |
2018-12-20 |
サンガモ セラピューティクス, インコーポレイテッド |
Mhc細胞受容体の標的化破壊
|
AU2016369490C1
(en)
|
2015-12-18 |
2021-12-23 |
Sangamo Therapeutics, Inc. |
Targeted disruption of the T cell receptor
|
US20170202931A1
(en)
|
2016-01-15 |
2017-07-20 |
Sangamo Therapeutics, Inc. |
Methods and compositions for the treatment of neurologic disease
|
JP7012650B2
(ja)
|
2016-02-02 |
2022-01-28 |
サンガモ セラピューティクス, インコーポレイテッド |
Dna結合ドメインと切断ドメインとを連結するための組成物
|
AU2017238512B2
(en)
|
2016-03-23 |
2022-12-08 |
Dana-Farber Cancer Institute, Inc. |
Methods for enhancing the efficiency of gene editing
|
CN109863143B
(zh)
|
2016-07-13 |
2021-10-15 |
威泰克斯制药公司 |
提高基因组编辑效率的方法、组合物和试剂盒
|
US11344511B2
(en)
|
2016-07-27 |
2022-05-31 |
Case Western Reserve University |
Compounds and methods of promoting myelination
|
JP7066126B2
(ja)
|
2016-08-09 |
2022-05-13 |
ブイアイビー ブイゼットダブリュ |
セルロースシンターゼ阻害剤および突然変異体植物
|
BR112019003327A2
(pt)
|
2016-08-24 |
2019-07-02 |
Sangamo Therapeutics Inc |
nucleases manipuladas de alvo específico
|
EP3995574A1
(de)
|
2016-08-24 |
2022-05-11 |
Sangamo Therapeutics, Inc. |
Regulierung der genexpression mit manipulierten nukleasen
|
CA3035534A1
(en)
|
2016-09-07 |
2018-03-15 |
Sangamo Therapeutics, Inc. |
Modulation of liver genes
|
KR20190062505A
(ko)
|
2016-10-03 |
2019-06-05 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Hpv-특이적 결합 분자
|
ES2811500T3
(es)
|
2016-10-04 |
2021-03-12 |
Prec Biosciences Inc |
Dominios coestimuladores para su uso en células genéticamente modificadas
|
CA3039673A1
(en)
|
2016-10-20 |
2018-04-26 |
Sangamo Therapeutics, Inc. |
Methods and compositions for the treatment of fabry disease
|
AU2017347928A1
(en)
|
2016-10-31 |
2019-05-09 |
Sangamo Therapeutics, Inc. |
Gene correction of scid-related genes in hematopoietic stem and progenitor cells
|
MX2019006426A
(es)
|
2016-12-01 |
2019-08-14 |
Sangamo Therapeutics Inc |
Reguladores de tau, y composiciones y metodos para su administracion.
|
EP3551754B1
(de)
|
2016-12-08 |
2023-08-30 |
Case Western Reserve University |
Verfahren und zusammensetzungen zur erhöhung der herstellung von funktionalem myelin
|
BR112019021993A2
(pt)
|
2017-04-20 |
2020-05-12 |
Oregon Health & Science University |
Correção de gene humano
|
CN110869497A
(zh)
|
2017-05-03 |
2020-03-06 |
桑格摩生物治疗股份有限公司 |
修饰囊性纤维化跨膜传导调节蛋白(cftr)基因的方法和组合物
|
CA3062698A1
(en)
|
2017-05-08 |
2018-11-15 |
Precision Biosciences, Inc. |
Nucleic acid molecules encoding an engineered antigen receptor and an inhibitory nucleic acid molecule and methods of use thereof
|
US11512287B2
(en)
|
2017-06-16 |
2022-11-29 |
Sangamo Therapeutics, Inc. |
Targeted disruption of T cell and/or HLA receptors
|
EP3645038A1
(de)
|
2017-06-30 |
2020-05-06 |
Precision Biosciences, Inc. |
Genetisch modifizierte t-zellen mit einem modifizierten intron im t-zell-rezeptor-alpha-gen
|
US20200239544A1
(en)
|
2017-10-03 |
2020-07-30 |
Precision Biosciences, Inc. |
Modified epidermal growth factor receptor peptides for use in genetically-modified cells
|
KR20200104284A
(ko)
|
2017-10-03 |
2020-09-03 |
주노 쎄러퓨티크스 인코퍼레이티드 |
Hpv-특이적 결합 분자
|
WO2019089913A1
(en)
|
2017-11-01 |
2019-05-09 |
Precision Biosciences, Inc. |
Engineered nucleases that target human and canine factor viii genes as a treatment for hemophilia a
|
US11661611B2
(en)
|
2017-11-09 |
2023-05-30 |
Sangamo Therapeutics, Inc. |
Genetic modification of cytokine inducible SH2-containing protein (CISH) gene
|
WO2019143678A1
(en)
|
2018-01-17 |
2019-07-25 |
Vertex Pharmaceuticals Incorporated |
Dna-pk inhibitors
|
US20200361877A1
(en)
|
2018-01-17 |
2020-11-19 |
Vertex Pharmaceuticals Incorporated |
Quinoxalinone compounds, compositions, methods, and kits for increasing genome editing efficiency
|
CA3088788A1
(en)
|
2018-01-17 |
2019-07-25 |
Vertex Pharmaceuticals Incorporated |
Dna-pk inhibitors
|
CA3089587A1
(en)
|
2018-02-08 |
2019-08-15 |
Sangamo Therapeutics, Inc. |
Engineered target specific nucleases
|
MX2020010459A
(es)
|
2018-04-05 |
2021-01-20 |
Juno Therapeutics Inc |
Metodos para producir celulas que expresan un receptor recombinante y composiciones relacionadas.
|
JP2021520211A
(ja)
|
2018-04-05 |
2021-08-19 |
ジュノー セラピューティクス インコーポレイテッド |
組換え受容体を発現するt細胞、関連ポリヌクレオチド、および方法
|
CA3095027A1
(en)
|
2018-04-05 |
2019-10-10 |
Juno Therapeutics, Inc. |
T cell receptors and engineered cells expressing same
|
US11421007B2
(en)
|
2018-04-18 |
2022-08-23 |
Sangamo Therapeutics, Inc. |
Zinc finger protein compositions for modulation of huntingtin (Htt)
|
US11690921B2
(en)
|
2018-05-18 |
2023-07-04 |
Sangamo Therapeutics, Inc. |
Delivery of target specific nucleases
|
WO2020041249A1
(en)
|
2018-08-23 |
2020-02-27 |
Sangamo Therapeutics, Inc. |
Engineered target specific base editors
|
EP3853244A4
(de)
|
2018-09-18 |
2022-09-14 |
Sangamo Therapeutics, Inc. |
Für programmierten zelltod 1 (pd1) spezifische nukleasen
|
WO2020132659A1
(en)
|
2018-12-21 |
2020-06-25 |
Precision Biosciences, Inc. |
Genetic modification of the hydroxyacid oxidase 1 gene for treatment of primary hyperoxaluria
|
SG11202106987WA
(en)
|
2019-01-11 |
2021-07-29 |
Acuitas Therapeutics Inc |
Lipids for lipid nanoparticle delivery of active agents
|
US11857641B2
(en)
|
2019-02-06 |
2024-01-02 |
Sangamo Therapeutics, Inc. |
Method for the treatment of mucopolysaccharidosis type I
|
MA55531A
(fr)
|
2019-04-02 |
2022-02-09 |
Sangamo Therapeutics Inc |
Procédés pour le traitement de béta-thalassémie
|
EP3947682B1
(de)
|
2019-04-03 |
2023-10-11 |
Precision Biosciences, Inc. |
Genetisch modifizierte immunzellen mit einer mikrorna-adaptierten shrna (shrnamir)
|
CA3136265A1
(en)
|
2019-04-05 |
2020-10-08 |
Precision Biosciences, Inc. |
Methods of preparing populations of genetically-modified immune cells
|
KR20220003561A
(ko)
|
2019-04-23 |
2022-01-10 |
상가모 테라퓨틱스, 인코포레이티드 |
염색체 9 오픈 리딩 프레임 72 유전자 발현의 조정제 및 그의 용도
|
WO2020223571A1
(en)
|
2019-05-01 |
2020-11-05 |
Juno Therapeutics, Inc. |
Cells expressing a chimeric receptor from a modified cd247 locus, related polynucleotides and methods
|
BR112021021075A2
(pt)
|
2019-05-01 |
2021-12-14 |
Editas Medicine Inc |
Células que expressam um receptor recombinante de um locus de tgfbr2 modificado, polinucleotídeos relacionados e métodos
|
WO2021016608A1
(en)
|
2019-07-25 |
2021-01-28 |
Precision Biosciences, Inc. |
Compositions and methods for sequential stacking of nucleic acid sequences into a genomic locus
|
JP2022544825A
(ja)
|
2019-08-20 |
2022-10-21 |
プレシジョン バイオサイエンシズ,インク. |
細胞免疫療法のためのリンパ球枯渇投与レジメン
|
WO2021035170A1
(en)
|
2019-08-21 |
2021-02-25 |
Precision Biosciences, Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
CN114466867A
(zh)
|
2019-10-02 |
2022-05-10 |
桑格摩生物治疗股份有限公司 |
用于抑制α-突触核蛋白表达的锌指蛋白转录因子
|
CN114728037A
(zh)
|
2019-10-02 |
2022-07-08 |
桑格摩生物治疗股份有限公司 |
用于朊病毒病治疗的锌指蛋白转录因子
|
US20220411479A1
(en)
|
2019-10-30 |
2022-12-29 |
Precision Biosciences, Inc. |
Cd20 chimeric antigen receptors and methods of use for immunotherapy
|
TW202132565A
(zh)
|
2019-11-01 |
2021-09-01 |
美商聖加莫治療股份有限公司 |
Gin重組酶變異體
|
EP4069285A1
(de)
|
2019-12-06 |
2022-10-12 |
Precision BioSciences, Inc. |
Methoden zur krebsimmuntherapie unter verwendung von lymphodepletionsregimen und allogenen cd19-, cd20- oder bcma-car-t-zellen
|
MX2022008953A
(es)
|
2020-01-22 |
2022-08-15 |
Sangamo Therapeutics Inc |
Factores de transcripcion de proteina de dedos de zinc para reprimir la expresion de tau.
|
WO2021158915A1
(en)
|
2020-02-06 |
2021-08-12 |
Precision Biosciences, Inc. |
Recombinant adeno-associated virus compositions and methods for producing and using the same
|
WO2021202513A1
(en)
|
2020-03-31 |
2021-10-07 |
Elo Life Systems |
Modulation of endogenous mogroside pathway genes in watermelon and other cucurbits
|
CN115715203A
(zh)
|
2020-05-06 |
2023-02-24 |
塞勒克提斯公司 |
对细胞进行基因修饰以递送治疗性蛋白质的方法
|
AU2021268253A1
(en)
|
2020-05-06 |
2022-12-08 |
Cellectis S.A. |
Methods for targeted insertion of exogenous sequences in cellular genomes
|
WO2021231259A1
(en)
|
2020-05-11 |
2021-11-18 |
Precision Biosciences, Inc. |
Self-limiting viral vectors encoding nucleases
|
WO2021231661A2
(en)
|
2020-05-13 |
2021-11-18 |
Juno Therapeutics, Inc. |
Process for producing donor-batched cells expressing a recombinant receptor
|
CN116234558A
(zh)
|
2020-06-26 |
2023-06-06 |
朱诺治疗学有限公司 |
条件性地表达重组受体的工程化t细胞、相关多核苷酸和方法
|
US11976019B2
(en)
|
2020-07-16 |
2024-05-07 |
Acuitas Therapeutics, Inc. |
Cationic lipids for use in lipid nanoparticles
|
WO2022035793A1
(en)
|
2020-08-10 |
2022-02-17 |
Precision Biosciences, Inc. |
Antibodies and fragments specific for b-cell maturation antigen and uses thereof
|
WO2022046760A2
(en)
|
2020-08-25 |
2022-03-03 |
Kite Pharma, Inc. |
T cells with improved functionality
|
WO2022067122A1
(en)
|
2020-09-25 |
2022-03-31 |
Sangamo Therapeutics, Inc. |
Zinc finger fusion proteins for nucleobase editing
|
WO2022076547A1
(en)
|
2020-10-07 |
2022-04-14 |
Precision Biosciences, Inc. |
Lipid nanoparticle compositions
|
CR20230175A
(es)
|
2020-10-23 |
2023-07-26 |
Elo Life Systems Inc |
Métodos para producir plantas de vainilla con mejor sabor y producción agronómica
|
EP4240756A1
(de)
|
2020-11-04 |
2023-09-13 |
Juno Therapeutics, Inc. |
Zellen zur expression eines chimären rezeptors aus einem modifizierten invarianten kettenlocus der cd3-immunglobulin-superfamilie und zugehörige polynukleotide und verfahren
|
CA3200855A1
(en)
|
2020-11-16 |
2022-05-19 |
Pig Improvement Company Uk Limited |
Influenza a-resistant animals having edited anp32 genes
|
WO2022165111A1
(en)
|
2021-01-28 |
2022-08-04 |
Precision Biosciences, Inc. |
Modulation of tgf beta signaling in genetically-modified eukaryotic cells
|
US20240141311A1
(en)
|
2021-04-22 |
2024-05-02 |
North Carolina State University |
Compositions and methods for generating male sterile plants
|
WO2023064872A1
(en)
|
2021-10-14 |
2023-04-20 |
Precision Biosciences, Inc. |
Combinations of anti-bcma car t cells and gamma secretase inhibitors
|
AU2022371430A1
(en)
|
2021-10-19 |
2024-05-30 |
Precision Biosciences, Inc. |
Gene editing methods for treating alpha-1 antitrypsin (aat) deficiency
|
WO2023081900A1
(en)
|
2021-11-08 |
2023-05-11 |
Juno Therapeutics, Inc. |
Engineered t cells expressing a recombinant t cell receptor (tcr) and related systems and methods
|
WO2023091910A1
(en)
|
2021-11-16 |
2023-05-25 |
Precision Biosciences, Inc. |
Methods for cancer immunotherapy
|
WO2023105244A1
(en)
|
2021-12-10 |
2023-06-15 |
Pig Improvement Company Uk Limited |
Editing tmprss2/4 for disease resistance in livestock
|
WO2023122722A1
(en)
|
2021-12-22 |
2023-06-29 |
Sangamo Therapeutics, Inc. |
Novel zinc finger fusion proteins for nucleobase editing
|
WO2023131616A1
(en)
|
2022-01-05 |
2023-07-13 |
Vib Vzw |
Means and methods to increase abiotic stress tolerance in plants
|
WO2023131637A1
(en)
|
2022-01-06 |
2023-07-13 |
Vib Vzw |
Improved silage grasses
|
WO2023144199A1
(en)
|
2022-01-26 |
2023-08-03 |
Vib Vzw |
Plants having reduced levels of bitter taste metabolites
|
WO2024013514A2
(en)
|
2022-07-15 |
2024-01-18 |
Pig Improvement Company Uk Limited |
Gene edited livestock animals having coronavirus resistance
|
WO2024100604A1
(en)
|
2022-11-09 |
2024-05-16 |
Juno Therapeutics Gmbh |
Methods for manufacturing engineered immune cells
|