WO2009047992A1 - Ｕｄｐ－グルクロン酸転移酵素およびそれをコードするポリヌクレオチド - Google Patents

Ｕｄｐ－グルクロン酸転移酵素およびそれをコードするポリヌクレオチド Download PDF

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Publication number
WO2009047992A1
WO2009047992A1 PCT/JP2008/067613 JP2008067613W WO2009047992A1 WO 2009047992 A1 WO2009047992 A1 WO 2009047992A1 JP 2008067613 W JP2008067613 W JP 2008067613W WO 2009047992 A1 WO2009047992 A1 WO 2009047992A1
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WO
WIPO (PCT)
Prior art keywords
seq
nucleotide sequence
polynucleotide encoding
udp
same
Prior art date
Application number
PCT/JP2008/067613
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English (en)
French (fr)
Inventor
Eiichiro Ono
Akio Noguchi
Yuko Fukui
Masako Mizutani
Original Assignee
Suntory Holdings Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Holdings Limited filed Critical Suntory Holdings Limited
Priority to BRPI0818531-0A2A priority Critical patent/BRPI0818531A2/pt
Priority to CA2702035A priority patent/CA2702035C/en
Priority to EP08838174.4A priority patent/EP2199388B1/en
Priority to US12/678,161 priority patent/US8628938B2/en
Priority to AU2008310396A priority patent/AU2008310396A1/en
Publication of WO2009047992A1 publication Critical patent/WO2009047992A1/ja
Priority to IL204643A priority patent/IL204643A0/en
Priority to EC2010010082A priority patent/ECSP10010082A/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/01—Hexosyltransferases (2.4.1)
    • C12Y204/01017—Glucuronosyltransferase (2.4.1.17)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

　本発明は、新たなＵＤＰ－グルクロン酸転移酵素、およびそれをコードするポリヌクレオチド（例えば、配列番号：４で表される塩基配列の第１番目～第１３５９番目の塩基配列、配列番号：１０で表される塩基配列の第１番目～第１３６５番目の塩基配列、配列番号：１２で表される塩基配列の第１番目～第１３７１番目の塩基配列、及び配列番号：２２で表される塩基配列の第１番目～第１３７１番目の塩基配列からなる群から選択される１つの塩基配列からなるポリヌクレオチドを含有するポリヌクレオチド；または配列番号：５、１１、１３及び２３からなる群から選択される１つのアミノ酸配列を有するタンパク質をコードするポリヌクレオチドを含有するポリヌクレオチド）などを提供する。これにより、基質特異性の広い、新たなＵＤＰ－グルクロン酸転移酵素が提供される。
PCT/JP2008/067613 2007-10-12 2008-09-29 Ｕｄｐ－グルクロン酸転移酵素およびそれをコードするポリヌクレオチド WO2009047992A1 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
BRPI0818531-0A2A BRPI0818531A2 (pt) 2007-10-12 2008-09-29 Poloinucleotídeo, proteína, vetor, transformante, métodos para produzir a protéina e uma glucuronida
CA2702035A CA2702035C (en) 2007-10-12 2008-09-29 Udp-glucuronyl transferase and polynucleotide encoding the same
EP08838174.4A EP2199388B1 (en) 2007-10-12 2008-09-29 Udp-glucuronyl transferase and polynucleotide encoding the same
US12/678,161 US8628938B2 (en) 2007-10-12 2008-09-29 Polynucleotide encoding UDP-glucuronyl transferase
AU2008310396A AU2008310396A1 (en) 2007-10-12 2008-09-29 UDP-glucuronyl transferase and polynucleotide encoding the same
IL204643A IL204643A0 (en) 2007-10-12 2010-03-21 Udp - glucuronyl transferase and polynucleotide encoding the same
EC2010010082A ECSP10010082A (es) 2007-10-12 2010-04-06 Udp-glucuronil transferasa y polinucleotido de codificacion

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007-267050 2007-10-12
JP2007267050 2007-10-12
JP2008-067185 2008-03-17
JP2008067185A JP4927774B2 (ja) 2007-10-12 2008-03-17 Ｕｄｐ−グルクロン酸転移酵素およびそれをコードするポリヌクレオチド

Publications (1)

Publication Number Publication Date
WO2009047992A1 true WO2009047992A1 (ja) 2009-04-16

Family

ID=40549137

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/067613 WO2009047992A1 (ja) 2007-10-12 2008-09-29 Ｕｄｐ－グルクロン酸転移酵素およびそれをコードするポリヌクレオチド

Country Status (13)

Country Link
US (1) US8628938B2 (ja)
EP (1) EP2199388B1 (ja)
JP (1) JP4927774B2 (ja)
KR (1) KR20100081981A (ja)
CN (1) CN101407816B (ja)
AU (1) AU2008310396A1 (ja)
BR (1) BRPI0818531A2 (ja)
CA (1) CA2702035C (ja)
CO (1) CO6210706A2 (ja)
EC (1) ECSP10010082A (ja)
RU (1) RU2010119028A (ja)
TW (1) TWI363799B (ja)
WO (1) WO2009047992A1 (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010084879A1 (ja) * 2009-01-21 2010-07-29 サントリーホールディングス株式会社 フラボノイド3位グルクロン酸転移酵素、及びそれをコードするポリヌクレオチド
WO2021230162A1 (ja) * 2020-05-11 2021-11-18 サントリーホールディングス株式会社 プレニルフラボノイドのグルクロン酸抱合体の製造方法

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Publication number Priority date Publication date Assignee Title
JP5192700B2 (ja) 2007-01-19 2013-05-08 サントリーホールディングス株式会社 新規配糖化酵素及びそれをコードするポリヌクレオチド
AU2008361302A1 (en) * 2008-09-04 2010-03-11 Suntory Holdings Limited Glucuronyltransferase and polynucleotide encoding the same
CN101575631B (zh) * 2009-05-15 2011-11-16 南开大学 一种半乳糖基转移酶修饰黄酮类糖苷化合物的方法
CN105087453B (zh) * 2014-05-05 2019-09-13 中国医学科学院药物研究所 用于生物催化黄酮类化合物葡萄糖醛酸苷化的基因工程菌
TWI795369B (zh) * 2016-09-23 2023-03-11 日商三得利控股股份有限公司 芝麻素酚或芝麻素酚配糖體之生產方法
CA3068398A1 (en) * 2017-07-03 2019-01-10 Suntory Holdings Limited Use of malonyltransferase gene
CN113462668A (zh) * 2018-09-19 2021-10-01 云南农业大学 齐墩果酸葡糖醛酸转移酶及其编码基因和应用
CN114292826B (zh) * 2021-12-14 2023-04-07 中国农业科学院油料作物研究所 花生糖基转移酶AhUGT4在糖基化白藜芦醇中的应用

Citations (1)

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Publication number Priority date Publication date Assignee Title
JP2005287403A (ja) 2004-03-31 2005-10-20 Suntory Ltd 脂質生産菌の育種方法およびその利用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7884066B2 (en) * 1999-10-05 2011-02-08 The Regents Of The University Of California NELL-1 enhanced bone mineralization
US7785601B2 (en) * 2002-12-31 2010-08-31 Sygnis Bioscience Gmbh & Co. Kg Methods of treating neurological conditions with hematopoietic growth factors
AU2004299755B2 (en) * 2003-12-17 2009-12-03 Suntory Holdings Limited Method of constructing yellow flower by regulating flavonoid synthesis system
WO2006091194A1 (en) * 2005-02-23 2006-08-31 North Carolina State University Alteration of tobacco alkaloid content through modification of specific cytochrome p450 genes

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
JP2005287403A (ja) 2004-03-31 2005-10-20 Suntory Ltd 脂質生産菌の育種方法およびその利用

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010084879A1 (ja) * 2009-01-21 2010-07-29 サントリーホールディングス株式会社 フラボノイド3位グルクロン酸転移酵素、及びそれをコードするポリヌクレオチド
WO2021230162A1 (ja) * 2020-05-11 2021-11-18 サントリーホールディングス株式会社 プレニルフラボノイドのグルクロン酸抱合体の製造方法

Also Published As

Publication number Publication date
BRPI0818531A2 (pt) 2014-10-14
AU2008310396A1 (en) 2009-04-16
EP2199388A4 (en) 2010-11-10
CA2702035A1 (en) 2009-04-16
TW200920844A (en) 2009-05-16
CN101407816A (zh) 2009-04-15
CA2702035C (en) 2016-09-06
TWI363799B (en) 2012-05-11
JP4927774B2 (ja) 2012-05-09
CN101407816B (zh) 2012-10-10
US8628938B2 (en) 2014-01-14
RU2010119028A (ru) 2011-11-20
CO6210706A2 (es) 2010-10-20
EP2199388B1 (en) 2014-11-05
JP2009106265A (ja) 2009-05-21
ECSP10010082A (es) 2010-06-29
EP2199388A1 (en) 2010-06-23
US20100323402A1 (en) 2010-12-23
KR20100081981A (ko) 2010-07-15

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