JP2005502061A5 - - Google Patents

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JP2005502061A5
JP2005502061A5 JP2003526515A JP2003526515A JP2005502061A5 JP 2005502061 A5 JP2005502061 A5 JP 2005502061A5 JP 2003526515 A JP2003526515 A JP 2003526515A JP 2003526515 A JP2003526515 A JP 2003526515A JP 2005502061 A5 JP2005502061 A5 JP 2005502061A5
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Japan
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particles
porous
group
hybrid
surface modifier
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JP2003526515A
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JP2005502061A (ja
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Priority claimed from US09/924,399 external-priority patent/US6686035B2/en
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JP2003526515A 2001-08-07 2002-08-07 クロマトグラフィー分離のための多孔質有機・無機ハイブリッド粒子、及びそれらの製造法 Pending JP2005502061A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/924,399 US6686035B2 (en) 1999-02-05 2001-08-07 Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
PCT/US2002/025250 WO2003022392A1 (en) 2001-08-07 2002-08-07 Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation

Related Child Applications (1)

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JP2008231653A Division JP4943396B2 (ja) 2001-08-07 2008-09-10 クロマトグラフィー分離のための多孔質有機・無機ハイブリッド粒子、及びそれらの製造法

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JP2005502061A JP2005502061A (ja) 2005-01-20
JP2005502061A5 true JP2005502061A5 (enExample) 2006-01-05

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JP2003526515A Pending JP2005502061A (ja) 2001-08-07 2002-08-07 クロマトグラフィー分離のための多孔質有機・無機ハイブリッド粒子、及びそれらの製造法
JP2008231653A Expired - Fee Related JP4943396B2 (ja) 2001-08-07 2008-09-10 クロマトグラフィー分離のための多孔質有機・無機ハイブリッド粒子、及びそれらの製造法

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JP2008231653A Expired - Fee Related JP4943396B2 (ja) 2001-08-07 2008-09-10 クロマトグラフィー分離のための多孔質有機・無機ハイブリッド粒子、及びそれらの製造法

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US (5) US6686035B2 (enExample)
EP (1) EP1450924A4 (enExample)
JP (2) JP2005502061A (enExample)
WO (1) WO2003022392A1 (enExample)

Families Citing this family (143)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7232520B1 (en) 1998-06-12 2007-06-19 Waters Investments Limited Ion exchange porous resins for solid phase extraction and chromatography
DE69936920T2 (de) * 1998-06-12 2008-05-15 Waters Investments Ltd., New Castle Neue poröse ionenaustauschharze für die festphasenextraktion und chromatographie
US6686035B2 (en) * 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
US6528167B2 (en) * 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface
US20090056541A1 (en) * 2001-08-01 2009-03-05 Davison Dale A Method and apparatus for high resolution flash chromatography
EP1417366A4 (en) * 2001-08-09 2010-10-27 Waters Technologies Corp INORGANIC / ORGANIC HYBRID MONOLITHIC MATERIALS FOR CHROMATOGRAPHIC SEPARATIONS AND PROCESS FOR THEIR PREPARATION
WO2003078159A1 (en) * 2002-03-13 2003-09-25 Regents Of The University Of Minnesota Silica-based materials and methods
AU2003284009A1 (en) * 2002-10-01 2004-06-07 Dow Corning Corporation Method of separating components in a sample using silane-treated silica filter media
US7264728B2 (en) * 2002-10-01 2007-09-04 Dow Corning Corporation Method of separating components in a sample using silane-treated silica filter media
WO2004041398A2 (en) * 2002-10-30 2004-05-21 Waters Investments Limited Porous inorganic/organic hybrid materials and preparation thereof
US7887754B2 (en) 2003-02-07 2011-02-15 Waters Technologies Corporation Polymeric solid supports for chromatography nanocolumns
GB2413508B (en) * 2003-02-10 2007-02-21 Waters Investments Ltd Siloxane-Immobilized particulate stationary phases for chromatographic separations and extractions
US20070141325A1 (en) * 2003-05-28 2007-06-21 Waters Investments Limited Novel nanocomposites and their application as monolith columns
US20060035054A1 (en) * 2004-01-05 2006-02-16 Aspen Aerogels, Inc. High performance vacuum-sealed insulations
JP2007524739A (ja) * 2004-01-06 2007-08-30 アスペン エアロゲルズ,インコーポレイティド ケイ素結合線状ポリマーを含有するオルモシルエーロゲル
CA2551843A1 (en) * 2004-01-06 2005-10-20 Aspen Aerogels, Inc. Ormosil aerogels containing silicon bonded polymethacrylate
DE112005000269T5 (de) * 2004-02-17 2007-01-25 Waters Investments Ltd., New Castle Poröse Hybridmonolithmaterialien mit von der Oberfläche entfernten organischen Gruppen
US7309426B2 (en) * 2004-04-23 2007-12-18 Agilent Technologies, Inc. Composition and method for high efficiency chromatography
US20060019084A1 (en) * 2004-07-23 2006-01-26 Pearson Laurence T Monolithic composition and method
US8658277B2 (en) * 2004-07-30 2014-02-25 Waters Technologies Corporation Porous inorganic/organic hybrid materials with ordered domains for chromatographic separations and processes for their preparation
US10773186B2 (en) 2004-07-30 2020-09-15 Waters Technologies Corporation Porous inorganic/organic hybrid materials with ordered domains for chromatographic separations and processes for their preparation
US7312175B2 (en) * 2004-08-18 2007-12-25 Battelle Energy Alliance, Llc Ion exchange materials, method of forming ion exchange materials, and methods of treating liquids
KR101318462B1 (ko) * 2004-09-01 2013-10-16 아스펜 에어로겔, 인코포레이티드 고성능 진공-밀폐 절연체
ES2579756T3 (es) 2004-10-01 2016-08-16 Phenomenex, Inc. Medio cromatográfico con pH estable que utiliza plantilla multicapa orgánica / inorgánica injertada
US9125968B2 (en) * 2005-03-30 2015-09-08 Boston Scientific Scimed, Inc. Polymeric/ceramic composite materials for use in medical devices
US20070014699A1 (en) * 2005-06-23 2007-01-18 Beckman Coulter, Inc, Methods and apparatus for improving the sensitivity of capillary zone electrophoresis
US8008395B2 (en) * 2005-09-27 2011-08-30 Boston Scientific Scimed, Inc. Organic-inorganic hybrid particle material and polymer compositions containing same
US20100113856A1 (en) * 2005-09-30 2010-05-06 Absorbent Materials Company Llc Apparatus and method for remediation of aqueous solutions
US20100108612A1 (en) * 2005-09-30 2010-05-06 Absorbent Materials Company Llc Apparatus and method for removing small molecule organic pharmaceuticals from aqueous solutions
US9440869B2 (en) 2005-09-30 2016-09-13 Abs Materials, Inc. Sol-gel derived compositions
US8367793B2 (en) * 2005-09-30 2013-02-05 Abs Materials, Inc. Swellable materials and methods of use
US9144784B2 (en) 2005-09-30 2015-09-29 Abs Materials Sorbent material and method for using the same
US7790830B2 (en) * 2005-09-30 2010-09-07 Wootech, Ltd. Swellable sol-gels, methods of making, and use thereof
US20070089604A1 (en) * 2005-10-20 2007-04-26 Wu Chen Novel chromatographic stationary phase
US9308520B2 (en) 2005-12-16 2016-04-12 Akzo Nobel N.V. Silica based material
KR20070079867A (ko) * 2006-02-04 2007-08-08 삼성전자주식회사 유-무기 하이브리드 중합체 및 이를 포함하는 유기 절연체조성물
WO2007092827A2 (en) * 2006-02-08 2007-08-16 Waters Investments Limited Improved separation method
US7947579B2 (en) 2006-02-13 2011-05-24 Stc.Unm Method of making dense, conformal, ultra-thin cap layers for nanoporous low-k ILD by plasma assisted atomic layer deposition
US20090206034A1 (en) * 2006-03-29 2009-08-20 Osakazu Nakajima Modified silica gel and use thereof
US9181486B2 (en) * 2006-05-25 2015-11-10 Aspen Aerogels, Inc. Aerogel compositions with enhanced performance
WO2008035125A2 (en) * 2006-09-22 2008-03-27 Analytical Nano Technologies Limited Methods
DE102006058200A1 (de) * 2006-12-11 2008-06-12 Merck Patent Gmbh Redispergierbare oberflächenmodifizierte Partikel
JP2010515804A (ja) 2007-01-12 2010-05-13 ウオーターズ・テクノロジーズ・コーポレイシヨン クロマトグラフ分離用多孔質炭素−ヘテロ原子−ケイ素ハイブリッド無機/有機材料およびその調製のための方法
US9120083B2 (en) * 2007-02-21 2015-09-01 Waters Technologies Corporation Porous inorganic/organic hybrid particles having high organic content and enhanced pore geometry for chromatographic separations
US20100278695A1 (en) * 2007-05-08 2010-11-04 Waters Technologies Corporation Chromatographic And Electrophoretic Separation Media And Apparatus
EP2212319B1 (en) 2007-10-31 2018-07-18 Alseres Pharmaceuticals, Inc. Labeled iodinated tropane formulation
WO2009102363A2 (en) * 2007-11-15 2009-08-20 Stc.Unm Ultra-thin microporous/hybrid materials
US8314201B2 (en) 2007-11-30 2012-11-20 The United States Of America As Represented By The Administration Of The National Aeronautics And Space Administration Highly porous ceramic oxide aerogels having improved flexibility
US8258251B2 (en) * 2007-11-30 2012-09-04 The United States Of America, As Represented By The Administrator Of The National Aeronautics And Space Administration Highly porous ceramic oxide aerogels having improved flexibility
US8367198B2 (en) 2007-12-19 2013-02-05 3M Innovative Properties Company Precisely-shaped porous particles
JP5449202B2 (ja) * 2008-02-25 2014-03-19 ウオーターズ・テクノロジーズ・コーポレイシヨン サンプル中のビタミンd類似体の存在および量の決定のための方法およびキット
KR101259015B1 (ko) * 2008-02-29 2013-04-29 삼성전자주식회사 재생 방법 및 장치
US9248383B2 (en) * 2008-04-08 2016-02-02 Waters Technologies Corporation Composite materials containing nanoparticles and their use in chromatography
US8277883B2 (en) * 2008-06-13 2012-10-02 Agilent Technologies, Inc. Porous silica microspheres having organosilane modified surfaces
US9284456B2 (en) 2008-08-29 2016-03-15 Agilent Technologies, Inc. Superficially porous metal oxide particles, methods for making them, and separation devices using them
US8357628B2 (en) 2008-08-29 2013-01-22 Agilent Technologies, Inc. Inorganic/organic hybrid totally porous metal oxide particles, methods for making them and separation devices using them
US8685283B2 (en) 2008-08-29 2014-04-01 Agilent Technologies, Inc. Superficially porous metal oxide particles, methods for making them, and separation devices using them
JP5620902B2 (ja) * 2009-03-12 2014-11-05 株式会社 資生堂 充填剤の製造方法、充填剤及びカラム
EP2437882A4 (en) 2009-06-01 2016-11-23 Waters Technologies Corp HYBRID MATERIAL FOR CHROMATOGRAPHY SEPARATIONS
US11439977B2 (en) 2009-06-01 2022-09-13 Waters Technologies Corporation Hybrid material for chromatographic separations comprising a superficially porous core and a surrounding material
EP2462188A4 (en) 2009-08-04 2016-11-23 Waters Technologies Corp HIGH-QUALITY CHROMATOGRAPHIC MATERIALS WITH A IONIZABLE MODIFIER
EP4023330A1 (en) 2009-12-15 2022-07-06 Waters Technologies Corporation Device and methods for performing size exclusion chromatography
US20130012379A1 (en) * 2010-01-08 2013-01-10 Abs Materials, Inc. Modified sol-gel derived sorbent material and method for using the same
JP5941405B2 (ja) * 2010-05-27 2016-06-29 株式会社ダイセル 薄層クロマトグラフィーによる試料の検出方法、薄層クロマトグラフィープレート、及びその製造方法
EP3834927B1 (en) 2010-07-26 2026-03-25 Waters Technologies Corporation Method for preparing a superficially porous material
US12623205B2 (en) 2010-07-26 2026-05-12 Waters Technologies Corporation Superficially porous materials comprising a substantially nonporous hybrid core having narrow particle size distribution
US20120205315A1 (en) 2011-02-14 2012-08-16 Dionex Corporation Nanometer size chemical modified materials and uses
EP2675889B1 (en) 2011-02-16 2018-08-22 Waters Technologies Corporation Immobilized enzymatic reactor
WO2013002909A1 (en) 2011-05-20 2013-01-03 Waters Technologies Corporation Porous materials for solid phase extraction and chromatography and processes for preparation and use thereof
CN102320819A (zh) * 2011-05-23 2012-01-18 江苏红旗环保工程有限公司 规整波纹陶瓷填料及其制备方法
KR20140051373A (ko) * 2011-08-02 2014-04-30 에이비에스 머티리얼즈 인코포레이티드 졸-겔 유래 조성물
EP2782965A4 (en) * 2011-11-23 2015-07-01 Momentive Performance Mat Inc PROCESS FOR THE PREPARATION OF ORGANIC-INORGANIC HYBRID MATERIALS
WO2013093022A1 (en) 2011-12-23 2013-06-27 Universiteit Gent Novel organosilica compounds
US20150136700A1 (en) 2012-05-15 2015-05-21 Waters Technologies Corporation Chromatographic materials
MY178616A (en) 2012-09-17 2020-10-19 Grace W R & Co Chromatography media and devices
US9610576B2 (en) 2012-09-27 2017-04-04 Agilent Technologies, Inc. Hydrolytically stable ion-exchange stationary phases and uses thereof
US9702856B2 (en) 2012-10-03 2017-07-11 Waters Technologies Corporation System and method for rapid analysis of polymer additives
FR2998891B1 (fr) * 2012-11-30 2015-04-10 Commissariat Energie Atomique Procede pour preparer un verre a porosite bimodale, eventuellement fonctionnalise et ledit verre
RU2527217C1 (ru) * 2012-12-27 2014-08-27 Александр Валерианович Пастухов Способ получения полимер-неорганических композитных сорбентов
US11577179B2 (en) 2013-06-11 2023-02-14 Waters Technologies Corporation Chromatographic columns and separation devices comprising a superficially porous material; and use thereof for supercritical fluid chromatography and other chromatography
US9518960B2 (en) * 2013-10-02 2016-12-13 Waters Technologies Corporation System and method for rapid analysis of polycyclic aromatic hydrocarbons
US11092574B2 (en) 2013-12-24 2021-08-17 Waters Technologies Corporation Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides
US10119944B2 (en) 2013-12-24 2018-11-06 Waters Technologies Corporation Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides
US20150224473A1 (en) 2014-02-07 2015-08-13 Thermo Electron Manufacturing Limited Chromatographic material and methods for the synthesis thereof
JP6914189B2 (ja) 2014-05-02 2021-08-04 ダブリュー・アール・グレース・アンド・カンパニー−コーンW R Grace & Co−Conn 官能化担体材料並びに官能化担体材料を作製及び使用する方法
CN107921407B (zh) 2015-06-05 2022-07-05 格雷斯公司 生物处理吸附澄清剂及其制备和使用方法
CN107923884B (zh) * 2015-08-25 2020-10-16 昭和电工株式会社 液相色谱用柱以及具备该液相色谱用柱的液相色谱装置
EP3377110B1 (en) 2015-11-20 2021-01-06 AbbVie Deutschland GmbH & Co. KG Nanoparticles based on optionally alkoxylated poly(alkyl cyanoacrylates) having a defined degree of polymerization
CN121869327A (zh) 2016-03-06 2026-04-17 沃特世科技公司 用于色谱分离的具有受控孔隙度的多孔材料;其制备方法;以及其用途
US10434496B2 (en) 2016-03-29 2019-10-08 Agilent Technologies, Inc. Superficially porous particles with dual pore structure and methods for making the same
US10501432B2 (en) 2016-04-01 2019-12-10 Waters Technologies Corporation Chiral separation of Δ8-THC, Δ9-THC, and related enantiomers using CO2-based chromatography
EP3449253B1 (en) 2016-04-24 2025-05-28 Waters Technologies Corporation Isolation of glycans modified with amphipathic, strongly basic moieties, using charged surface reversed phase chromatopgraphic materials
US10618920B2 (en) * 2016-06-03 2020-04-14 Agilent Technologies, Inc. Functionalized particles having modified phases
EP3491374B1 (en) 2016-07-28 2024-10-09 Waters Technologies Corporation Encapsulated pre-analytic workflow reagents for flow-through devices, liquid chromatography and mass spectrometric analysis
WO2018163086A1 (en) 2017-03-08 2018-09-13 Waters Technologies Corporation Polar pesticide determination using chromatography
US9925515B1 (en) * 2017-03-24 2018-03-27 The Florida International University Board Of Trustees Alkyl functionalized porous silica liquid chromatographic stationary phases and solid phase extraction sorbents
US11709155B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US11709156B2 (en) 2017-09-18 2023-07-25 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved analytical analysis
US12181452B2 (en) 2017-09-18 2024-12-31 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
US12180581B2 (en) 2017-09-18 2024-12-31 Waters Technologies Corporation Use of vapor deposition coated flow paths for improved chromatography of metal interacting analytes
WO2019067632A1 (en) 2017-09-26 2019-04-04 Waters Technologies Corporation LIQUID CHROMATOGRAPHY SEPARATION OF GLUCIDIC TAUTOMERS
WO2019067637A1 (en) 2017-09-26 2019-04-04 Waters Technologies Corporation HIGH-PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER FOR RETENTION OF ACID ANALYTES
WO2019239329A1 (en) 2018-06-12 2019-12-19 Waters Technologies Corporation Size exclusion chromatography of biological molecules
EP3821238B1 (en) 2018-07-11 2022-08-31 Waters Technologies Corporation Chromatographic system and method for trap-elute mixed mode chromatography
US11307183B2 (en) 2018-07-18 2022-04-19 Waters Technologies Corporation Methods for determination of polar pesticides by chromatography
US11391707B2 (en) 2018-07-27 2022-07-19 Waters Technologies Corporation Liquid chromatography/mass spectrometry methods for the analysis of polar molecules
WO2020072668A1 (en) 2018-10-02 2020-04-09 Waters Technologies Corporation Sorbents, devices, kits and methods useful for biological sample treatment
KR102716678B1 (ko) * 2019-05-15 2024-10-15 주식회사 엘지화학 산화방지제의 고속 분리 및 분석을 위한 방법 및 시스템
EP4054757A1 (en) * 2019-11-07 2022-09-14 Waters Technologies Corporation Materials and methods for mixed mode, anion exchange reversed phase liquid chromatography
WO2021111418A1 (en) 2019-12-05 2021-06-10 Waters Technologies Corporation Polyphosphonic acids for improving recovery and minimizing system loss
CN111036526B (zh) * 2019-12-31 2022-04-29 丹阳双峰玻璃有限公司 一种安全覆硅胶膜玻璃奶瓶生产工艺
US11918936B2 (en) 2020-01-17 2024-03-05 Waters Technologies Corporation Performance and dynamic range for oligonucleotide bioanalysis through reduction of non specific binding
EP4121203A1 (en) 2020-03-20 2023-01-25 Restek Corporation Spike particles, superficially porous spike particles, chromatographic separation devices, and processes for forming spike particles
EP4136441A1 (en) 2020-04-15 2023-02-22 Waters Technologies Corporation Guard column configurations for size exclusion chromatography separations
WO2021211856A1 (en) 2020-04-15 2021-10-21 Waters Technologies Corporation Sec performance enhancing conditioning and storage solvents containing low levels of buffer and salt
US11964874B2 (en) 2020-06-09 2024-04-23 Agilent Technologies, Inc. Etched non-porous particles and method of producing thereof
US20220017887A1 (en) 2020-07-14 2022-01-20 Waters Technologies Corporation Compositions, kits and methods useful for separating oligonucleotides from matrix components
CN116209517B (zh) 2020-09-16 2026-06-16 沃特世科技公司 具有羟基封端的peg键合和甲氧基封端的peg表面改性的基于二氧化硅的颗粒
WO2022061035A1 (en) 2020-09-16 2022-03-24 Waters Technologies Corporation Improved size exclusion chromatography utilizing low concentration amino acids in size exclusion chromatography mobile phase
WO2022064447A1 (en) 2020-09-24 2022-03-31 Waters Technologies Corporation Chromatographic hardware improvements for the separation of reactive molecules
US12201975B2 (en) 2020-10-16 2025-01-21 Waters Technologies Corporation Device including a hydrophilic, non-ionic coating for size exclusion chromatography
CA3207750A1 (en) 2020-12-11 2022-06-16 Genentech, Inc. Methods for determining the relative distribution of glucuronidation, iduronidation, and galacturonidation of polypeptides
US20220362741A1 (en) 2021-04-29 2022-11-17 Waters Technologies Corporation Hydrolytically stable zwitterionic chromatographic materials
WO2022254401A1 (en) 2021-06-04 2022-12-08 Waters Technologies Corporation Separation of nucleic acid component compounds on zwitterionic stationary phases
US20230101326A1 (en) 2021-08-26 2023-03-30 Waters Technologies Corporation Core-shell particles with organic polymer cores
WO2023089538A1 (en) 2021-11-19 2023-05-25 Waters Technologies Corporation A double surface modified porous material with minimized nonspecific interaction
EP4479156A1 (en) 2022-02-19 2024-12-25 Waters Technologies Corporation Novel size exclusion chromatography column technologies for analysis of crispr molecules
US20240082820A1 (en) 2022-08-26 2024-03-14 Waters Technologies Corporation Core-shell particles having a non-porous core and a porous shell
CN119744199A (zh) 2022-08-26 2025-04-01 沃特世科技公司 无孔杂化涂覆聚合物颗粒
CN119744197A (zh) 2022-08-26 2025-04-01 沃特世科技公司 具有无孔有机-无机杂化材料的复合颗粒
WO2024042372A1 (en) 2022-08-26 2024-02-29 Waters Technologies Corporation Bonded hybrid polymer non-porous particles and their use for bioseparations
CN120187522A (zh) 2022-10-31 2025-06-20 沃特世科技公司 消除反相液相色谱中的保留损失的多组分表面化学
EP4648873A1 (en) 2023-01-11 2025-11-19 Waters Technologies Corporation Dipodal silane bonded sorbents for solid phase extraction and use thereof for oligonucleotide extraction
US20240241095A1 (en) * 2023-01-12 2024-07-18 Agilent Technologies, Inc. Chromatography column for the separation of surfactants
US20240286110A1 (en) * 2023-02-25 2024-08-29 Chrom6 Technologies, LLC Carbon microsphere chromatographic material
CN121127312A (zh) 2023-05-05 2025-12-12 沃特世科技公司 用于亲和色谱的蛋白a/g颗粒及其使用方法
US20250270538A1 (en) 2024-02-28 2025-08-28 Waters Technologies Corporation Methods for the separation of nucleic acids with slalom chromatography
US20250283860A1 (en) 2024-03-08 2025-09-11 Waters Technologies Corporation Methods for chromatographic characterization of lipid nanoparticle compositions
US20250298009A1 (en) 2024-03-22 2025-09-25 Waters Technologies Corporation Methods for characterizing lipid nanoparticle compositions
WO2025219970A1 (en) 2024-04-19 2025-10-23 Waters Technologies Corporation Dextran improves the sizing analysis of lipid nanoparticles during size exclusion chromatography analysis
WO2025250776A1 (en) * 2024-05-29 2025-12-04 Advanced Materials Technologies, Inc. A ph stable chromatographic material and method of producing the same
WO2025255028A1 (en) 2024-06-03 2025-12-11 Amgen Inc. High-throughput liquid chromatography-mass spectrometry-based peptide mapping
WO2026136851A1 (en) 2024-12-20 2026-06-25 Amgen Inc. Methods of diethylenetriaminepentaacetic acid (dtpa) quantification

Family Cites Families (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US127177A (en) * 1872-05-28 Improvement in swivels for rock and well boring machines
US3935299A (en) 1972-05-11 1976-01-27 Andrei Vladimirovich Kiselev Process for preparation of wide-pore adsorbent for use in chromatography
DE2236862C2 (de) 1972-07-27 1974-09-05 Istvan Prof. Dr. 6600 Saarbruecken Halasz Sorptionsmittel für die Chromatographie
DE2357184A1 (de) 1973-11-16 1975-05-22 Merck Patent Gmbh Verfahren zur herstellung von organisch modifizierten siliciumdioxiden
US4029583A (en) 1975-02-28 1977-06-14 Purdue Research Foundation Chromatographic supports and methods and apparatus for preparing the same
CS179184B1 (en) 1975-07-25 1977-10-31 Stanislav Vozka Method for preparation of precisely spherical particles of silica gel with controlled size and controled size pores.
DE2642032C2 (de) 1976-09-18 1987-04-30 Rupprecht, Herbert, Prof. Dr., 8400 Regensburg Verfahren zur Inkorporierung von Wirkstoffen in siliciumdioxidhaltige Trägermaterialien und eine siliciumdioxidhaltige Zubereitung
FR2464967A1 (fr) 1979-09-07 1981-03-20 Rhone Poulenc Ind Preparation de resines echangeuses d'anions par bromation de polymeres vinylaromatiques
US4324689A (en) 1980-02-26 1982-04-13 Shah Ramesh M High carbon content chromatographic packing and method for making same
US4334118A (en) 1981-06-01 1982-06-08 Chevron Research Solid phosphoric acid catalyzed olefin polymerization process
JPS58120525A (ja) 1982-01-05 1983-07-18 Asahi Glass Co Ltd 珪酸塩中空球の製造方法
JPS5954619A (ja) 1982-09-24 1984-03-29 Asahi Glass Co Ltd 珪酸塩粒状体の製造方法
US4724207A (en) 1984-02-02 1988-02-09 Cuno Incorporated Modified siliceous chromatographic supports
JPS60257358A (ja) * 1984-06-05 1985-12-19 Daicel Chem Ind Ltd 分離用充填剤
US5177128A (en) * 1985-07-10 1993-01-05 Sequa Chemicals, Inc. Paper coating composition
DE3616133A1 (de) 1985-09-25 1987-11-19 Merck Patent Gmbh Kugelfoermige sio(pfeil abwaerts)2(pfeil abwaerts)-partikel
US5108595A (en) 1985-11-01 1992-04-28 E. I. Du Pont De Nemours And Company Porous silica microspheres having silanol-enriched and silanized surfaces
GB8618322D0 (en) 1986-07-28 1986-09-03 3I Res Expl Ltd Bonded chromotographic stationary phase
US5256386A (en) 1987-06-29 1993-10-26 Eka Nobel Ab Method for preparation of silica particles
US4889632A (en) * 1987-12-10 1989-12-26 Ceskoslovenska Akademie Ved Macroporous polymeric membranes for the separation of polymers and a method of their application
EP0386926A3 (en) 1989-03-02 1991-12-18 Supelco, Inc. Silica gel supports suitable for chromatographic separations
US5403908A (en) 1989-10-06 1995-04-04 Idemitsu Kosan Company, Limited Aryl styrene-based copolymer
US6022902A (en) 1989-10-31 2000-02-08 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Porous article with surface functionality and method for preparing same
US4983369A (en) 1989-11-22 1991-01-08 Allied-Signal Inc. Process for forming highly uniform silica spheres
US5068387A (en) 1989-12-01 1991-11-26 Dow Corning Corporation Production of organofunctional alkoxysilanes
JP2874297B2 (ja) 1989-12-18 1999-03-24 東ソー株式会社 逆相クロマトグラフィー用充填剤及びその製造方法
US5271833A (en) * 1990-03-22 1993-12-21 Regents Of The University Of Minnesota Polymer-coated carbon-clad inorganic oxide particles
JP2646150B2 (ja) 1990-08-27 1997-08-25 出光興産 株式会社 撥水性シリカゾルおよびその製造方法
JPH0617476B2 (ja) 1990-09-04 1994-03-09 工業技術院長 有機基修飾シリカ粒子、その製造方法および該粒子をフィラーとする樹脂組成物
JPH04210227A (ja) * 1990-12-10 1992-07-31 Res Dev Corp Of Japan 細孔構造を制御した有機シリカ多孔体及びシリカ多孔体の製造方法
US5071565A (en) 1991-02-04 1991-12-10 Iowa State University Research Foundation, Inc. Modified resins for solid-phase extraction
JP3168006B2 (ja) * 1991-10-21 2001-05-21 コーネル・リサーチ・フアウンデーシヨン・インコーポレーテツド マクロ細孔ポリマー媒体が備わっているカラム
US5734020A (en) 1991-11-20 1998-03-31 Cpg, Inc. Production and use of magnetic porous inorganic materials
US5565142A (en) 1992-04-01 1996-10-15 Deshpande; Ravindra Preparation of high porosity xerogels by chemical surface modification.
WO1993023333A1 (en) 1992-05-20 1993-11-25 E.I. Du Pont De Nemours And Company Process for making inorganic gels
JP3440486B2 (ja) 1992-06-19 2003-08-25 旭硝子株式会社 球状シリカの製造方法
US5298833A (en) * 1992-06-22 1994-03-29 Copytele, Inc. Black electrophoretic particles for an electrophoretic image display
US5374755A (en) 1992-07-17 1994-12-20 Millipore Corporation Liquid chromatography stationary phases with reduced silanol interactions
US5378790A (en) * 1992-09-16 1995-01-03 E. I. Du Pont De Nemours & Co. Single component inorganic/organic network materials and precursors thereof
US5498678A (en) 1992-12-21 1996-03-12 Rohm And Haas Company Suspension polymerization process for water-soluble monomers
DE69407295T2 (de) 1993-07-19 1998-06-25 Merck Patent Gmbh, 64293 Darmstadt Anorganisches, poröses material und verfahren zu dessen herstellung
US5425930A (en) 1993-09-17 1995-06-20 Alliedsignal Inc. Process for forming large silica spheres by low temperature nucleation
JPH07113011A (ja) * 1993-10-18 1995-05-02 Nippon Sheet Glass Co Ltd 多孔質体及びこれを充填材とするカラム及びこれらの製造方法
DE69425473T3 (de) * 1993-11-05 2005-11-03 Shin-Etsu Chemical Co., Ltd. Verfahren zur Herstellung von Organo-funktionelle Gruppen enthaltenden Organopolysiloxanen und daraus hergestellte Organopolysiloxane, Mercapto- und Alkoxygruppen enthaltende Organopolysiloxane und Verfahren zu deren Herstellung
JP2893104B2 (ja) 1994-03-14 1999-05-17 直弘 曽我 有機官能基の結合した無機系多孔質体の製造方法
US5728457A (en) * 1994-09-30 1998-03-17 Cornell Research Foundation, Inc. Porous polymeric material with gradients
US5868966A (en) * 1995-03-30 1999-02-09 Drexel University Electroactive inorganic organic hybrid materials
US5637135A (en) 1995-06-26 1997-06-10 Capillary Technology Corporation Chromatographic stationary phases and adsorbents from hybrid organic-inorganic sol-gels
US5667674A (en) * 1996-01-11 1997-09-16 Minnesota Mining And Manufacturing Company Adsorption medium and method of preparing same
JP3818689B2 (ja) 1996-01-16 2006-09-06 富士写真フイルム株式会社 コロイド状シリカをコアとし、有機ポリマーをシェルとするコア/シェル状複合粒子の水性分散物及びその製造方法
US5869152A (en) 1996-03-01 1999-02-09 The Research Foundation Of State University Of New York Silica materials
JPH09278485A (ja) 1996-04-11 1997-10-28 Tosoh Corp 耐アルカリ性球状ガラスとその製造方法
US6313219B1 (en) * 1996-05-02 2001-11-06 Lucent Technologies, Inc. Method for hybrid inorganic/organic composite materials
US5965202A (en) 1996-05-02 1999-10-12 Lucent Technologies, Inc. Hybrid inorganic-organic composite for use as an interlayer dielectric
US5853886A (en) * 1996-06-17 1998-12-29 Claytec, Inc. Hybrid nanocomposites comprising layered inorganic material and methods of preparation
AU7533696A (en) 1996-12-13 1998-06-18 Ciba-Geigy Ag New materials
DE69716126T2 (de) * 1996-12-26 2003-06-05 Merck Patent Gmbh Anorganisches, poröses material und verfahren zu dessen herstellung
US5976479A (en) 1996-12-30 1999-11-02 Uop Llc Hydrothermal process for preparing a unimodal large pore silica
US5935429A (en) 1997-01-03 1999-08-10 Bio-Rad Laboratories, Inc. Chromatography columns with continuous beds formed in situ from aqueous solutions
WO1998038251A1 (de) 1997-02-25 1998-09-03 Bayer Aktiengesellschaft Organisch-anorganische hybridmaterialien
WO1998056498A1 (en) * 1997-06-13 1998-12-17 California Institute Of Technology Porous silica having spatially organized organic functionalities
EP0991940B1 (de) 1997-06-18 2010-08-25 Merck Patent GmbH Verwendung monolithischer sorbentien für präparative chromatographische trennverfahren
US6027643A (en) 1997-09-04 2000-02-22 Dionex Corporation Ion chromatographic method and apparatus using a combined suppressor and eluent generator
US6136187A (en) * 1997-12-09 2000-10-24 The Board Of Trustees Of The Leland Stanford Junior University Separation column containing porous matrix and method of packing column
US6592764B1 (en) 1997-12-09 2003-07-15 The Regents Of The University Of California Block copolymer processing for mesostructured inorganic oxide materials
DE19756831A1 (de) * 1997-12-19 1999-07-01 Wacker Chemie Gmbh Siliciumdioxid, das an seiner Oberfläche teil- oder vollständig silylierte Polykieselsäureketten trägt
US6281257B1 (en) * 1998-04-27 2001-08-28 The Regents Of The University Of Michigan Porous composite materials
JP3899733B2 (ja) * 1998-07-03 2007-03-28 株式会社豊田中央研究所 多孔材料及び多孔材料の製造方法
JP3953649B2 (ja) * 1998-07-17 2007-08-08 オリヱント化学工業株式会社 有機−無機ハイブリッド成分傾斜高分子材料、及びその製造方法
US6210570B1 (en) * 1998-08-21 2001-04-03 Agilent Technologies, Inc. Monolithic silica column
US6090477A (en) * 1998-09-11 2000-07-18 Ut-Battelle, Llc Gas storage carbon with enhanced thermal conductivity
US6238565B1 (en) * 1998-09-16 2001-05-29 Varian, Inc. Monolithic matrix for separating bio-organic molecules
DE19856000A1 (de) * 1998-12-04 2000-06-15 Bayer Ag Hybridlack-Zubereitung
EP1733786B1 (en) 1999-02-05 2010-04-14 Waters Technologies Corporation Porous hybrid particles for chromatographic separations
US6686035B2 (en) 1999-02-05 2004-02-03 Waters Investments Limited Porous inorganic/organic hybrid particles for chromatographic separations and process for their preparation
US6227304B1 (en) 1999-03-01 2001-05-08 Case Corporation Upper hitch link
JP4214203B2 (ja) 1999-05-18 2009-01-28 オリヱント化学工業株式会社 有機−無機複合材料およびその製造方法
US20060194919A1 (en) 1999-08-04 2006-08-31 Lichtenhan Joseph D Porosity control with polyhedral oligomeric silsesquioxanes
US6649083B1 (en) 1999-08-12 2003-11-18 Board Of Trustees Of Michigan State University Combined porous organic and inorganic oxide materials prepared by non-ionic surfactant templating route
SE9903223L (sv) 1999-09-09 2001-05-08 Ericsson Telefon Ab L M Förfarande och anordning i telekommunikationssystem
US6251280B1 (en) 1999-09-15 2001-06-26 University Of Tennessee Research Corporation Imprint-coating synthesis of selective functionalized ordered mesoporous sorbents for separation and sensors
JP4525879B2 (ja) * 1999-10-14 2010-08-18 戸田工業株式会社 多孔性機能粉体及びその製造法
TW588072B (en) 2000-10-10 2004-05-21 Shipley Co Llc Antireflective porogens
US6528167B2 (en) 2001-01-31 2003-03-04 Waters Investments Limited Porous hybrid particles with organic groups removed from the surface
EP1417366A4 (en) * 2001-08-09 2010-10-27 Waters Technologies Corp INORGANIC / ORGANIC HYBRID MONOLITHIC MATERIALS FOR CHROMATOGRAPHIC SEPARATIONS AND PROCESS FOR THEIR PREPARATION
WO2004041398A2 (en) 2002-10-30 2004-05-21 Waters Investments Limited Porous inorganic/organic hybrid materials and preparation thereof
DE112005000269T5 (de) 2004-02-17 2007-01-25 Waters Investments Ltd., New Castle Poröse Hybridmonolithmaterialien mit von der Oberfläche entfernten organischen Gruppen
US8658277B2 (en) 2004-07-30 2014-02-25 Waters Technologies Corporation Porous inorganic/organic hybrid materials with ordered domains for chromatographic separations and processes for their preparation
US7439272B2 (en) 2004-12-20 2008-10-21 Varian, Inc. Ultraporous sol gel monoliths
JP2010515804A (ja) 2007-01-12 2010-05-13 ウオーターズ・テクノロジーズ・コーポレイシヨン クロマトグラフ分離用多孔質炭素−ヘテロ原子−ケイ素ハイブリッド無機/有機材料およびその調製のための方法
US9120083B2 (en) 2007-02-21 2015-09-01 Waters Technologies Corporation Porous inorganic/organic hybrid particles having high organic content and enhanced pore geometry for chromatographic separations

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