JP2004513885A5 - - Google Patents
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- Publication number
- JP2004513885A5 JP2004513885A5 JP2002523486A JP2002523486A JP2004513885A5 JP 2004513885 A5 JP2004513885 A5 JP 2004513885A5 JP 2002523486 A JP2002523486 A JP 2002523486A JP 2002523486 A JP2002523486 A JP 2002523486A JP 2004513885 A5 JP2004513885 A5 JP 2004513885A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- alkyl
- kit
- compound
- following
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CC1C(C)(C*)C(C2)C2C1 Chemical compound CC1C(C)(C*)C(C2)C2C1 0.000 description 4
- NXJVKVNWKOZSHW-UHFFFAOYSA-N CCc1ncc[n]1CC(c1cc(Cl)ccc11)=Cc2cccnc2C1N(CC1)CCN1C(Nc(cc1)ccc1C#N)=O Chemical compound CCc1ncc[n]1CC(c1cc(Cl)ccc11)=Cc2cccnc2C1N(CC1)CCN1C(Nc(cc1)ccc1C#N)=O NXJVKVNWKOZSHW-UHFFFAOYSA-N 0.000 description 1
- MLRHVXRSUCIJCY-UHFFFAOYSA-N Cc1ncc[n]1CC(c1cc(Br)cnc11)=Cc2ccccc2C1N(CC1)CCN1C(Nc(cc1)ccc1C#N)=O Chemical compound Cc1ncc[n]1CC(c1cc(Br)cnc11)=Cc2ccccc2C1N(CC1)CCN1C(Nc(cc1)ccc1C#N)=O MLRHVXRSUCIJCY-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22918300P | 2000-08-30 | 2000-08-30 | |
| PCT/US2001/026792 WO2002018368A1 (en) | 2000-08-30 | 2001-08-28 | Tricyclic antitumor compounds being farnesyl protein transferase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004513885A JP2004513885A (ja) | 2004-05-13 |
| JP2004513885A5 true JP2004513885A5 (enExample) | 2008-09-25 |
Family
ID=22860141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002523486A Pending JP2004513885A (ja) | 2000-08-30 | 2001-08-28 | ファルネシルタンパク質トランスフェラーゼインヒビターである三環式抗腫瘍化合物 |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US20020198216A1 (enExample) |
| EP (1) | EP1313725B1 (enExample) |
| JP (1) | JP2004513885A (enExample) |
| KR (1) | KR20030034161A (enExample) |
| CN (1) | CN100384837C (enExample) |
| AR (1) | AR033680A1 (enExample) |
| AT (1) | ATE359281T1 (enExample) |
| AU (2) | AU2001288451C1 (enExample) |
| BR (1) | BR0113675A (enExample) |
| CA (1) | CA2420673A1 (enExample) |
| CO (1) | CO5640109A2 (enExample) |
| DE (1) | DE60127846T2 (enExample) |
| EC (1) | ECSP034494A (enExample) |
| ES (1) | ES2284686T3 (enExample) |
| HK (1) | HK1054548B (enExample) |
| HU (1) | HUP0302942A3 (enExample) |
| IL (1) | IL154528A0 (enExample) |
| MX (1) | MXPA03001849A (enExample) |
| NO (1) | NO20030918L (enExample) |
| NZ (1) | NZ524246A (enExample) |
| PE (1) | PE20020486A1 (enExample) |
| PL (1) | PL361103A1 (enExample) |
| RU (1) | RU2293734C9 (enExample) |
| SK (1) | SK2292003A3 (enExample) |
| TW (1) | TWI268280B (enExample) |
| WO (1) | WO2002018368A1 (enExample) |
| ZA (1) | ZA200301545B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7342016B2 (en) * | 2000-08-30 | 2008-03-11 | Schering Corporation | Farnesyl protein transferase inhibitors as antitumor agents |
| HU230273B1 (hu) * | 2001-03-14 | 2015-11-30 | Bristol-Myers Squibb Company | Egy epotilon analóg és kemoterápiás szerek kombinációja proliferatív betegségek kezelésére |
| AU2002340139A1 (en) * | 2001-10-09 | 2003-04-22 | The University Of Cincinnati | Inhibitors of the egf receptor for the treatment of thyroid cancer |
| CN1617755A (zh) * | 2001-11-30 | 2005-05-18 | 先灵公司 | 法尼基蛋白转移酶抑制剂和其它抗肿瘤剂联合使用在制备抗癌症的药物中的应用 |
| MXPA04005425A (es) * | 2001-12-03 | 2004-10-11 | Schering Corp | Uso de inhibidores de farnesil proteina transferasa y por lo menos dos agentes antineoplasicos en el tratamiento de cancer. |
| US20030195192A1 (en) * | 2002-04-05 | 2003-10-16 | Fortuna Haviv | Nicotinamides having antiangiogenic activity |
| US20040014744A1 (en) * | 2002-04-05 | 2004-01-22 | Fortuna Haviv | Substituted pyridines having antiangiogenic activity |
| US7714139B2 (en) * | 2003-03-27 | 2010-05-11 | Lankenau Institute For Medcial Research | IDO inhibitors and methods of use |
| US20060281813A1 (en) * | 2003-06-05 | 2006-12-14 | Charles Rubin | Methods of treating hyperproliferative cell disorders |
| CN1972712A (zh) * | 2003-06-09 | 2007-05-30 | 塞缪尔·瓦克萨尔 | 用胞外拮抗物和胞内拮抗物抑制受体酪氨酸激酶的方法 |
| ES2235611B2 (es) * | 2003-07-25 | 2006-07-16 | Universidade De Santiago De Compostela | Metodo cuantitativo para la deteccion de yesotoxinas en productos pesqueros basado en la activacion que producen en las fosfodiesterasas. |
| BRPI0413384A (pt) * | 2003-08-07 | 2006-10-17 | Schering Corp | inibidores da proteìna farnesil transferase como agentes antitumores |
| US7592466B2 (en) | 2003-10-09 | 2009-09-22 | Abbott Laboratories | Ureas having antiangiogenic activity |
| WO2006069208A2 (en) * | 2004-12-21 | 2006-06-29 | Schering Corporation | Novel farnesyl protein transferase inhibitors as antitumor agents |
| RU2361587C1 (ru) * | 2008-02-14 | 2009-07-20 | Михаил Владимирович Кутушов | Лекарственное средство для лечения онкологических заболеваний |
| CA2730190A1 (en) * | 2008-07-14 | 2010-01-21 | Queen's University At Kingston | Pharmaceutical compositions comprising ret inhibitors and methods for the treatment of cancer |
| EP3989956A1 (en) * | 2019-06-28 | 2022-05-04 | Anhui Ronghang Biotech Development Co., Ltd. | Compositions and methods for treatment of hepatitis b virus infection |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
| IE68935B1 (en) * | 1990-06-22 | 1996-07-24 | Schering Corp | Bis-benzo or benzopyrido cyclohepta piperidene piperidylidene and piperazine compounds compositions and methods of use |
| US5719148A (en) * | 1993-10-15 | 1998-02-17 | Schering Corporation | Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases |
| PE92098A1 (es) * | 1996-07-31 | 1998-12-31 | Schering Corp | N-cianoiminas triciclicas utiles como inhibidores de transferasa de proteina farnesilo |
| US6071907A (en) * | 1996-09-13 | 2000-06-06 | Schering Corporation | Tricyclic compounds useful as FPT inhibitors |
| US5925648A (en) * | 1997-07-29 | 1999-07-20 | Schering Corporation | Tricyclic N-cyanoimines useful as inhibitors of a farnesyl-protein transferase |
| KR20010081115A (ko) * | 1998-12-18 | 2001-08-27 | 둘락 노먼 씨. | 파르네실 단백질 트랜스퍼라제 억제제 |
-
2001
- 2001-08-27 AR ARP010104082A patent/AR033680A1/es unknown
- 2001-08-28 IL IL15452801A patent/IL154528A0/xx unknown
- 2001-08-28 NZ NZ524246A patent/NZ524246A/en unknown
- 2001-08-28 ES ES01968188T patent/ES2284686T3/es not_active Expired - Lifetime
- 2001-08-28 DE DE60127846T patent/DE60127846T2/de not_active Expired - Fee Related
- 2001-08-28 BR BR0113675-5A patent/BR0113675A/pt not_active IP Right Cessation
- 2001-08-28 CA CA002420673A patent/CA2420673A1/en not_active Abandoned
- 2001-08-28 JP JP2002523486A patent/JP2004513885A/ja active Pending
- 2001-08-28 CN CNB01818121XA patent/CN100384837C/zh not_active Expired - Fee Related
- 2001-08-28 PL PL01361103A patent/PL361103A1/xx unknown
- 2001-08-28 AT AT01968188T patent/ATE359281T1/de not_active IP Right Cessation
- 2001-08-28 MX MXPA03001849A patent/MXPA03001849A/es active IP Right Grant
- 2001-08-28 AU AU2001288451A patent/AU2001288451C1/en not_active Ceased
- 2001-08-28 HK HK03105016.6A patent/HK1054548B/en not_active IP Right Cessation
- 2001-08-28 PE PE2001000865A patent/PE20020486A1/es not_active Application Discontinuation
- 2001-08-28 WO PCT/US2001/026792 patent/WO2002018368A1/en not_active Ceased
- 2001-08-28 TW TW090121201A patent/TWI268280B/zh active
- 2001-08-28 US US09/940,811 patent/US20020198216A1/en not_active Abandoned
- 2001-08-28 SK SK229-2003A patent/SK2292003A3/sk not_active Application Discontinuation
- 2001-08-28 KR KR10-2003-7003012A patent/KR20030034161A/ko not_active Ceased
- 2001-08-28 HU HU0302942A patent/HUP0302942A3/hu unknown
- 2001-08-28 EP EP01968188A patent/EP1313725B1/en not_active Expired - Lifetime
- 2001-08-28 AU AU8845101A patent/AU8845101A/xx active Pending
- 2001-08-28 RU RU2003108865/04A patent/RU2293734C9/ru not_active IP Right Cessation
-
2003
- 2003-02-25 ZA ZA200301549A patent/ZA200301545B/xx unknown
- 2003-02-26 EC EC2003004494A patent/ECSP034494A/es unknown
- 2003-02-27 CO CO03017118A patent/CO5640109A2/es active IP Right Grant
- 2003-02-27 NO NO20030918A patent/NO20030918L/no not_active Application Discontinuation
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