JP2004511430A - 二重特異性免疫グロブリン様抗原結合蛋白および製造方法 - Google Patents
二重特異性免疫グロブリン様抗原結合蛋白および製造方法 Download PDFInfo
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
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- Heart & Thoracic Surgery (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
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|---|---|---|---|
| US20674900P | 2000-05-24 | 2000-05-24 | |
| PCT/US2001/016924 WO2001090192A2 (en) | 2000-05-24 | 2001-05-24 | Bispecific immunoglobulin-like antigen binding proteins and method of production |
Publications (2)
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| JP2004511430A true JP2004511430A (ja) | 2004-04-15 |
| JP2004511430A5 JP2004511430A5 (cg-RX-API-DMAC7.html) | 2008-07-17 |
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| US (2) | US20020103345A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1299419A2 (cg-RX-API-DMAC7.html) |
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| CA (1) | CA2409991A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2001090192A2 (cg-RX-API-DMAC7.html) |
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| JP2005526482A (ja) * | 2001-08-10 | 2005-09-08 | イムクローン システムズ インコーポレイティド | Vegfr−1を発現する幹細胞の単離および動員 |
| JP2009504191A (ja) * | 2005-08-19 | 2009-02-05 | アボット・ラボラトリーズ | 二重可変ドメイン免疫グロブリン及びその使用 |
| JP2010535032A (ja) * | 2007-07-31 | 2010-11-18 | メディミューン,エルエルシー | 多重特異性エピトープ結合性タンパク質およびその用途 |
| JP2012228248A (ja) * | 2005-08-19 | 2012-11-22 | Abbott Lab | 二重可変ドメイン免疫グロブリン及びその使用 |
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| JP2005518336A (ja) * | 2001-06-26 | 2005-06-23 | イムクローン システムズ インコーポレイティド | Vegf受容体に結合する二重特異性抗体 |
| JP2005526482A (ja) * | 2001-08-10 | 2005-09-08 | イムクローン システムズ インコーポレイティド | Vegfr−1を発現する幹細胞の単離および動員 |
| JP2009504191A (ja) * | 2005-08-19 | 2009-02-05 | アボット・ラボラトリーズ | 二重可変ドメイン免疫グロブリン及びその使用 |
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| JP2010535032A (ja) * | 2007-07-31 | 2010-11-18 | メディミューン,エルエルシー | 多重特異性エピトープ結合性タンパク質およびその用途 |
Also Published As
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| WO2001090192A3 (en) | 2003-01-16 |
| EP1299419A2 (en) | 2003-04-09 |
| US20020103345A1 (en) | 2002-08-01 |
| WO2001090192A2 (en) | 2001-11-29 |
| AU2001264946A1 (en) | 2001-12-03 |
| US20040259156A1 (en) | 2004-12-23 |
| CA2409991A1 (en) | 2001-11-29 |
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