JP2004505992A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2004505992A5 JP2004505992A5 JP2002518258A JP2002518258A JP2004505992A5 JP 2004505992 A5 JP2004505992 A5 JP 2004505992A5 JP 2002518258 A JP2002518258 A JP 2002518258A JP 2002518258 A JP2002518258 A JP 2002518258A JP 2004505992 A5 JP2004505992 A5 JP 2004505992A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- hepatitis
- reducing agent
- vaccine
- free
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0019728.5A GB0019728D0 (en) | 2000-08-10 | 2000-08-10 | Novel treatment |
| GB0101334A GB0101334D0 (en) | 2001-01-18 | 2001-01-18 | Novel compounds |
| PCT/EP2001/009100 WO2002012287A1 (en) | 2000-08-10 | 2001-08-07 | Purification of hbv antigens for use in vaccines |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012180462A Division JP5559847B2 (ja) | 2000-08-10 | 2012-08-16 | ワクチンに使用するためのhbv抗原の精製 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004505992A JP2004505992A (ja) | 2004-02-26 |
| JP2004505992A5 true JP2004505992A5 (OSRAM) | 2005-03-03 |
Family
ID=26244821
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002518258A Pending JP2004505992A (ja) | 2000-08-10 | 2001-08-07 | ワクチンに使用するためのhbv抗原の精製 |
| JP2012180462A Expired - Lifetime JP5559847B2 (ja) | 2000-08-10 | 2012-08-16 | ワクチンに使用するためのhbv抗原の精製 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012180462A Expired - Lifetime JP5559847B2 (ja) | 2000-08-10 | 2012-08-16 | ワクチンに使用するためのhbv抗原の精製 |
Country Status (35)
| Country | Link |
|---|---|
| US (3) | US20030235590A1 (OSRAM) |
| EP (2) | EP1666487B1 (OSRAM) |
| JP (2) | JP2004505992A (OSRAM) |
| KR (1) | KR100804922B1 (OSRAM) |
| CN (1) | CN1468256B (OSRAM) |
| AP (1) | AP2003002734A0 (OSRAM) |
| AR (1) | AR030325A1 (OSRAM) |
| AT (2) | ATE313558T1 (OSRAM) |
| AU (2) | AU2001282073B2 (OSRAM) |
| BG (1) | BG66038B1 (OSRAM) |
| BR (1) | BRPI0113155C1 (OSRAM) |
| CA (2) | CA2740282A1 (OSRAM) |
| CY (2) | CY1106310T1 (OSRAM) |
| CZ (1) | CZ303217B6 (OSRAM) |
| DE (2) | DE60136400D1 (OSRAM) |
| DK (2) | DK1666487T3 (OSRAM) |
| DZ (1) | DZ3470A1 (OSRAM) |
| EA (1) | EA006433B1 (OSRAM) |
| EG (1) | EG25829A (OSRAM) |
| ES (2) | ES2314555T3 (OSRAM) |
| HU (1) | HU228932B1 (OSRAM) |
| IL (2) | IL154301A0 (OSRAM) |
| MX (1) | MXPA03001235A (OSRAM) |
| MY (1) | MY128999A (OSRAM) |
| NO (1) | NO20030635L (OSRAM) |
| NZ (1) | NZ524012A (OSRAM) |
| OA (1) | OA12361A (OSRAM) |
| PE (1) | PE20020287A1 (OSRAM) |
| PL (1) | PL204736B1 (OSRAM) |
| PT (1) | PT1666487E (OSRAM) |
| SI (2) | SI1307473T1 (OSRAM) |
| SK (2) | SK288069B6 (OSRAM) |
| UA (1) | UA79735C2 (OSRAM) |
| UY (1) | UY26882A1 (OSRAM) |
| WO (1) | WO2002012287A1 (OSRAM) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA79735C2 (uk) * | 2000-08-10 | 2007-07-25 | Глаксосмітклайн Байолоджікалз С.А. | Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах |
| GB0202901D0 (en) * | 2002-02-07 | 2002-03-27 | Glaxosmithkline Biolog Sa | Novel vaccine |
| BRPI0613025A2 (pt) * | 2005-07-11 | 2010-12-14 | Globeimmune Inc | composiÇço para reduzir a resistÊncia a um agente, mÉtodo para a preparaÇço de um veÍculo de levedura e uso da composiÇço |
| KR101321732B1 (ko) * | 2005-08-02 | 2013-10-29 | 노바티스 백신즈 앤드 다이아그노스틱스 에스.알.엘. | 오일-함유 보조제 및 계면활성제-함유 항원 사이의 간섭감소 |
| GB0522765D0 (en) * | 2005-11-08 | 2005-12-14 | Chiron Srl | Combination vaccine manufacture |
| GB0612142D0 (en) | 2006-06-20 | 2006-08-02 | Secr Defence | Spreading modulation spectrum control |
| SI2097102T1 (sl) * | 2006-09-07 | 2012-09-28 | Glaxosmithkline Biolog Sa | Kombinirano cepivo, ki ima zmanjšane količine antigena za poliovirus |
| PE20090212A1 (es) | 2007-05-02 | 2009-03-30 | Glaxosmithkline Biolog Sa | Kit de vacuna para la inmunizacion primaria |
| JP5214627B2 (ja) * | 2007-10-30 | 2013-06-19 | 京セラ株式会社 | 弾性波装置 |
| US8250102B2 (en) * | 2008-03-14 | 2012-08-21 | Microsoft Corporation | Remote storage and management of binary object data |
| KR100959145B1 (ko) | 2008-03-21 | 2010-05-25 | 중앙대학교 산학협력단 | 인유두종바이러스 바이러스 유사 입자의 생산 및 정제 방법 |
| CA2725329C (en) | 2008-05-23 | 2013-10-01 | The Regents Of The University Of Michigan | Nanoemulsion vaccines |
| PE20120400A1 (es) * | 2009-05-27 | 2012-05-04 | Glaxosmithkline Biolog Sa | Contrucciones de casb7439 |
| US20130302837A1 (en) * | 2011-01-14 | 2013-11-14 | Hal Allergy Holding B.V. | Immunoassay for Direct Determination of Antigen Content of Products Comprising Adjuvant-Coupled-Antigen Particles |
| GB201105981D0 (en) | 2011-04-08 | 2011-05-18 | Glaxosmithkline Biolog Sa | Novel process |
| CN106222129A (zh) * | 2016-07-29 | 2016-12-14 | 广东东阳光药业有限公司 | 一种提高抗体纯度的细胞培养基和培养方法 |
| MX2020000441A (es) | 2017-07-18 | 2020-08-17 | Serum Inst Of India Pvt Ltd | Una composicion inmunogenica que tiene estabilidad mejorada, inmunogeneicidad potenciada y reactogenicidad reducida y proceso para la preparacion de la misma. |
| GB201721069D0 (en) | 2017-12-15 | 2018-01-31 | Glaxosmithkline Biologicals Sa | Hepatitis B Immunisation regimen and compositions |
| GB201721068D0 (en) | 2017-12-15 | 2018-01-31 | Glaxosmithkline Biologicals Sa | Hepatitis B immunisation regimen and compositions |
| EP3934687A1 (en) | 2019-03-05 | 2022-01-12 | GlaxoSmithKline Biologicals S.A. | Hepatitis b immunisation regimen and compositions |
| US12453769B2 (en) * | 2019-12-13 | 2025-10-28 | Grand Theravac Life Sciences (Nanjing) Co., Ltd. | Pharmaceutical composition and use thereof |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1030777A (en) * | 1963-12-06 | 1966-05-25 | Ciba Ltd | Method of preparing a vaccine against trypanosoma cruzi infections |
| US4235877A (en) | 1979-06-27 | 1980-11-25 | Merck & Co., Inc. | Liposome particle containing viral or bacterial antigenic subunit |
| US4372945A (en) | 1979-11-13 | 1983-02-08 | Likhite Vilas V | Antigen compounds |
| IL61904A (en) | 1981-01-13 | 1985-07-31 | Yeda Res & Dev | Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same |
| US4720385A (en) * | 1983-03-29 | 1988-01-19 | Miles Laboratories, Inc. | Protein compositions substantially free from infectious agents |
| JPS6013718A (ja) | 1983-07-05 | 1985-01-24 | Chemo Sero Therapeut Res Inst | B型肝炎ワクチン |
| EP0135435A3 (en) | 1983-08-22 | 1987-03-25 | Merck & Co. Inc. | Immunogenic hbsag derived from transformed yeast |
| US4683294A (en) * | 1985-04-03 | 1987-07-28 | Smith Kline Rit, S.A. | Process for the extraction and purification of proteins from culture media producing them |
| FI861417A0 (fi) | 1985-04-15 | 1986-04-01 | Endotronics Inc | Hepatitis b ytantigen framstaelld med rekombinant-dna-teknik, vaccin, diagnostiskt medel och cellinjer samt foerfaranden foer framstaellning daerav. |
| US4649192A (en) * | 1985-05-30 | 1987-03-10 | Smith Kline-Rit | Method for the isolation and purification of hepatitis B surface antigen using polysorbate |
| US4895800A (en) | 1985-11-26 | 1990-01-23 | Phillips Petroleum Company | Yeast production of hepatitis B surface antigen |
| ZA88488B (en) | 1987-01-30 | 1988-10-26 | Smith Kline Rit | Hepatitis b virus surface antigens and hybrid antigens containing them |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| EP1088830A3 (en) | 1987-06-22 | 2004-04-07 | Medeva Holdings B.V. | Hepatitis b surface antigen particles |
| DE3789866T2 (de) | 1987-07-17 | 1994-09-22 | Rhein Biotech Gesellschaft Fuer Neue Biotechnologische Prozesse Und Produkte Mbh, 40595 Duesseldorf | DNA-Moleküle, die für FMDH-Kontrollabschnitte und Strukturgene für ein Protein mit FMDH-Aktivität kodieren, sowie deren Anwendung. |
| EP0314240A3 (en) * | 1987-10-26 | 1990-03-28 | Merck & Co. Inc. | Process for purifying recombinant hepatitis antigens |
| JPH085804B2 (ja) | 1988-04-28 | 1996-01-24 | 財団法人化学及血清療法研究所 | A型及びb型肝炎混合アジュバントワクチン |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| US5242812A (en) * | 1989-02-07 | 1993-09-07 | Bio-Technology General Corp. | Method for production and purification of hepatitis B vaccine |
| US5274081A (en) * | 1989-09-20 | 1993-12-28 | Immuno A.G. | Complex suitable for carrying out a method of purifying pre-S hepatitis B surface antigen |
| GB9007024D0 (en) | 1990-03-29 | 1990-05-30 | Imperial College | Novel vaccine |
| JPH06503821A (ja) | 1990-12-20 | 1994-04-28 | スミスクライン・ビーチャム・バイオロジカルス(ソシエテ・アノニム) | B型肝炎表面抗原に基づくワクチン |
| JP3026029B2 (ja) | 1991-04-26 | 2000-03-27 | 財団法人阪大微生物病研究会 | 組換え水痘ウイルスとその作製法 |
| WO1993005811A1 (en) | 1991-09-18 | 1993-04-01 | Amgen Inc. | A hepatitis b vaccine formulation incorporating a bile acid salt |
| US6620414B2 (en) * | 1992-03-27 | 2003-09-16 | Smithkline Beecham Biologicals (S.A.) | Hepatitis vaccines containing 3-0-deacylated monophoshoryl lipid A |
| CA2138997C (en) | 1992-06-25 | 2003-06-03 | Jean-Paul Prieels | Vaccine composition containing adjuvants |
| GB9326253D0 (en) | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
| DK0772619T4 (da) | 1994-07-15 | 2011-02-21 | Univ Iowa Res Found | Immunmodulatoriske oligonukleotider |
| CZ296806B6 (cs) * | 1994-10-24 | 2006-06-14 | Allergan, Inc. | Rozpustný fúzní protein a zpusob výroby rozpustného rekombinantního botulinového toxinu |
| KR960023066A (ko) * | 1994-12-10 | 1996-07-18 | 성재갑 | 전에스 (s) 2 펩티드 함유 비 (b) 형 간염 표면항원의 정제 방법 |
| UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
| KR20010041629A (ko) | 1998-03-09 | 2001-05-25 | 장 스테판느 | 혼합 백신 조성물 |
| PT1104306E (pt) | 1998-08-10 | 2006-05-31 | Antigenics Inc | Composicoes de cpg e adjuvantes de saponina e seus metodos |
| WO2000037104A1 (en) * | 1998-12-23 | 2000-06-29 | Merck & Co., Inc. | Improved recombinant hepatitis b surface antigen |
| UA79735C2 (uk) * | 2000-08-10 | 2007-07-25 | Глаксосмітклайн Байолоджікалз С.А. | Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах |
-
2001
- 2001-07-08 UA UA2003021025A patent/UA79735C2/uk unknown
- 2001-08-07 DE DE60136400T patent/DE60136400D1/de not_active Expired - Lifetime
- 2001-08-07 EA EA200300129A patent/EA006433B1/ru not_active IP Right Cessation
- 2001-08-07 CA CA2740282A patent/CA2740282A1/en not_active Abandoned
- 2001-08-07 DZ DZ013470A patent/DZ3470A1/fr active
- 2001-08-07 AP APAP/P/2003/002734A patent/AP2003002734A0/en unknown
- 2001-08-07 JP JP2002518258A patent/JP2004505992A/ja active Pending
- 2001-08-07 PL PL362322A patent/PL204736B1/pl unknown
- 2001-08-07 AU AU2001282073A patent/AU2001282073B2/en not_active Expired
- 2001-08-07 SK SK169-2003A patent/SK288069B6/sk not_active IP Right Cessation
- 2001-08-07 AT AT01960630T patent/ATE313558T1/de active
- 2001-08-07 AT AT05077471T patent/ATE412665T1/de active
- 2001-08-07 IL IL15430101A patent/IL154301A0/xx unknown
- 2001-08-07 MX MXPA03001235A patent/MXPA03001235A/es active IP Right Grant
- 2001-08-07 DK DK05077471T patent/DK1666487T3/da active
- 2001-08-07 PT PT05077471T patent/PT1666487E/pt unknown
- 2001-08-07 DE DE60116107T patent/DE60116107T2/de not_active Expired - Lifetime
- 2001-08-07 SK SK50032-2012A patent/SK288079B6/sk not_active IP Right Cessation
- 2001-08-07 ES ES05077471T patent/ES2314555T3/es not_active Expired - Lifetime
- 2001-08-07 HU HU0302951A patent/HU228932B1/hu not_active IP Right Cessation
- 2001-08-07 OA OA1200300038A patent/OA12361A/en unknown
- 2001-08-07 WO PCT/EP2001/009100 patent/WO2002012287A1/en not_active Ceased
- 2001-08-07 EP EP05077471A patent/EP1666487B1/en not_active Expired - Lifetime
- 2001-08-07 SI SI200130489T patent/SI1307473T1/sl unknown
- 2001-08-07 CZ CZ20030385A patent/CZ303217B6/cs not_active IP Right Cessation
- 2001-08-07 SI SI200130884T patent/SI1666487T1/sl unknown
- 2001-08-07 BR BRPI0113155A patent/BRPI0113155C1/pt not_active IP Right Cessation
- 2001-08-07 KR KR1020037001933A patent/KR100804922B1/ko not_active Expired - Lifetime
- 2001-08-07 DK DK01960630T patent/DK1307473T3/da active
- 2001-08-07 CA CA2427475A patent/CA2427475C/en not_active Expired - Lifetime
- 2001-08-07 NZ NZ524012A patent/NZ524012A/en unknown
- 2001-08-07 AU AU8207301A patent/AU8207301A/xx active Pending
- 2001-08-07 EP EP01960630A patent/EP1307473B1/en not_active Expired - Lifetime
- 2001-08-07 US US10/344,211 patent/US20030235590A1/en not_active Abandoned
- 2001-08-07 CN CN018169988A patent/CN1468256B/zh not_active Expired - Lifetime
- 2001-08-07 ES ES01960630T patent/ES2254464T3/es not_active Expired - Lifetime
- 2001-08-08 EG EG2001080869A patent/EG25829A/xx active
- 2001-08-08 AR ARP010103790A patent/AR030325A1/es active IP Right Grant
- 2001-08-08 PE PE2001000786A patent/PE20020287A1/es not_active Application Discontinuation
- 2001-08-10 MY MYPI20013779A patent/MY128999A/en unknown
- 2001-08-10 UY UY26882A patent/UY26882A1/es not_active Application Discontinuation
-
2003
- 2003-02-05 IL IL154301A patent/IL154301A/en active IP Right Grant
- 2003-02-07 NO NO20030635A patent/NO20030635L/no unknown
- 2003-02-07 BG BG107545A patent/BG66038B1/bg unknown
-
2005
- 2005-11-03 US US11/266,565 patent/US20060159705A1/en not_active Abandoned
-
2006
- 2006-03-07 CY CY20061100311T patent/CY1106310T1/el unknown
-
2008
- 2008-12-10 CY CY20081101440T patent/CY1108789T1/el unknown
- 2008-12-23 US US12/342,220 patent/US8624004B2/en not_active Expired - Lifetime
-
2012
- 2012-08-16 JP JP2012180462A patent/JP5559847B2/ja not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2004505992A5 (OSRAM) | ||
| CA2427475A1 (en) | Purification of hbv antigens for use in vaccines | |
| RU2194531C2 (ru) | Поливалентные ассоциированные коклюшно-дифтерийно-столбнячно (акдс)-полиомиелитные вакцины | |
| CA2452720A1 (en) | Vaccines comprising aluminium adjuvants and histidine | |
| JP4980868B2 (ja) | 非細胞性百日咳ワクチンおよびその製造方法 | |
| Strugnell et al. | Vaccine antigens | |
| RU2007139924A (ru) | Вакцины, содержащие алюминиевые адъюванты и гистидин | |
| RU2000116260A (ru) | Вакцины с адъювантом ltb | |
| BR122012003821B8 (pt) | composição imunogênica multivalente, uso da mesma, e, processo para produzir a composição imunogênica | |
| RU2016150422A (ru) | Комбинированная семивалентная вакцина | |
| ES2257769T3 (es) | Metodo para la preparacion de vacunas multivalentes. | |
| EP1267938A1 (en) | Proteins for use as carriers in conjugate vaccines | |
| PT732937E (pt) | Adjuvante nao toxico das mucosas | |
| RU2005125832A (ru) | Способ очистки бактериального цитолизина | |
| RU99101850A (ru) | Поливалентные ассоциированные коклюшно-дифтерийно-столбнячно(акдс)-полиомиелитные вакцины | |
| JPH07116053B2 (ja) | 抗原性調製物および該調製物の単離法 | |
| JP2003500040A5 (OSRAM) | ||
| RU2121365C1 (ru) | Комбинированная вакцина, способ одновременной комбинированной вакцинации и способ повышения иммуногенности | |
| JP2012506420A (ja) | 全細胞百日咳を含む混合ワクチン | |
| RU2447898C2 (ru) | Вакцина ipv-dpt | |
| JP2009514840A5 (OSRAM) | ||
| JPH04505158A (ja) | 非細胞性ワクチン | |
| CN111701018A (zh) | 环二核苷酸修饰铝纳米粒疫苗佐剂-传递系统 | |
| US4857318A (en) | Bordetella bronchiseptica pilus subunit protein vaccine effective against bordetella pertussis | |
| RU2001129663A (ru) | Вакцина против ящура типа О и способ ее изготовления |