JP2003535907A - 抗体誘導性細胞溶解を促進し、そして癌を処置するための方法 - Google Patents

抗体誘導性細胞溶解を促進し、そして癌を処置するための方法

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Publication number
JP2003535907A
JP2003535907A JP2002503327A JP2002503327A JP2003535907A JP 2003535907 A JP2003535907 A JP 2003535907A JP 2002503327 A JP2002503327 A JP 2002503327A JP 2002503327 A JP2002503327 A JP 2002503327A JP 2003535907 A JP2003535907 A JP 2003535907A
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JP
Japan
Prior art keywords
nucleic acid
antibody
cancer
cells
lymphoma
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Pending
Application number
JP2002503327A
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English (en)
Japanese (ja)
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JP2003535907A5 (enExample
Inventor
ジョージ ワイナー，
グントヘア ハルトマン，
Original Assignee
ユニバーシティ オブ アイオワ リサーチ ファウンデーション
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Application filed by ユニバーシティ オブ アイオワ リサーチ ファウンデーション filed Critical ユニバーシティ オブ アイオワ リサーチ ファウンデーション
Publication of JP2003535907A publication Critical patent/JP2003535907A/ja
Publication of JP2003535907A5 publication Critical patent/JP2003535907A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2002503327A 2000-06-22 2001-06-22 抗体誘導性細胞溶解を促進し、そして癌を処置するための方法 Pending JP2003535907A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21334600P 2000-06-22 2000-06-22
US60/213,346 2000-06-22
PCT/US2001/020154 WO2001097843A2 (en) 2000-06-22 2001-06-22 Methods for enhancing antibody-induced cell lysis and treating cancer

Publications (2)

Publication Number Publication Date
JP2003535907A true JP2003535907A (ja) 2003-12-02
JP2003535907A5 JP2003535907A5 (enExample) 2008-08-07

Family

ID=22794755

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002503327A Pending JP2003535907A (ja) 2000-06-22 2001-06-22 抗体誘導性細胞溶解を促進し、そして癌を処置するための方法

Country Status (12)

Country Link
US (1) US7534772B2 (enExample)
EP (1) EP1296714B1 (enExample)
JP (1) JP2003535907A (enExample)
AT (1) ATE440618T1 (enExample)
AU (5) AU7013401A (enExample)
CA (1) CA2410371C (enExample)
DE (1) DE60139689D1 (enExample)
DK (1) DK1296714T3 (enExample)
ES (1) ES2332444T3 (enExample)
PT (1) PT1296714E (enExample)
SI (1) SI1296714T1 (enExample)
WO (1) WO2001097843A2 (enExample)

Cited By (11)

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JP2007518709A (ja) * 2003-12-19 2007-07-12 アンティセンス ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング 医薬組成物
JP2007531746A (ja) * 2004-04-02 2007-11-08 コーリー ファーマシューティカル グループ，インコーポレイテッド Ｉｌ−１０応答を誘導するための免疫活性化核酸
JP2008530142A (ja) * 2005-02-15 2008-08-07 デューク ユニバーシティ 抗ｃｄ１９抗体および腫瘍学における使用
JP2010507361A (ja) * 2006-07-31 2010-03-11 キュアバック ゲーエムベーハー 具体的には免疫刺激剤／アジュバントとしての、一般式（Ｉ）：ＧｌＸｍＧｎ、または一般式（ＩＩ）：ＣｌＸｍＣｎで表される核酸
JP2010525811A (ja) * 2007-05-04 2010-07-29 インデックス・ファーマシューティカルズ・アクチエボラーグ 腫瘍増殖阻害化合物及びそれらの使用方法
JP2012500847A (ja) * 2008-08-25 2012-01-12 アンプリミューン、インコーポレーテッド Ｐｄ−１アンタゴニストの組成物および使用方法
JP2012200233A (ja) * 2011-03-28 2012-10-22 National Institute For Materials Science 免疫刺激オリゴヌクレオチドおよび前記免疫刺激オリゴヌクレオチドを含む治療剤
JP2012211143A (ja) * 2005-05-05 2012-11-01 Duke Univ 自己免疫疾患のための抗ｃｄ１９抗体治療
JP2017507922A (ja) * 2014-01-22 2017-03-23 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 抗体のためおよび抗体が充填された樹状細胞を介した療法のための方法および組成物
US11110178B2 (en) 2016-07-07 2021-09-07 The Board Of Trustees Of The Leland Standford Junior University Antibody adjuvant conjugates
US11400164B2 (en) 2019-03-15 2022-08-02 Bolt Biotherapeutics, Inc. Immunoconjugates targeting HER2

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