PL2696878T3 - Schemat dawkowania dla sapacytabiny i decytabiny w kombinacji do leczenia ostrej białaczki szpikowej - Google Patents
Schemat dawkowania dla sapacytabiny i decytabiny w kombinacji do leczenia ostrej białaczki szpikowejInfo
- Publication number
- PL2696878T3 PL2696878T3 PL12717824T PL12717824T PL2696878T3 PL 2696878 T3 PL2696878 T3 PL 2696878T3 PL 12717824 T PL12717824 T PL 12717824T PL 12717824 T PL12717824 T PL 12717824T PL 2696878 T3 PL2696878 T3 PL 2696878T3
- Authority
- PL
- Poland
- Prior art keywords
- sapacitabine
- decitabine
- combination
- myeloid leukemia
- acute myeloid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1106339.3A GB201106339D0 (en) | 2011-04-14 | 2011-04-14 | Combination |
GBGB1117693.0A GB201117693D0 (en) | 2011-10-13 | 2011-10-13 | Combination |
GBGB1121105.9A GB201121105D0 (en) | 2011-12-08 | 2011-12-08 | Combination |
PCT/GB2012/050815 WO2012140436A1 (en) | 2011-04-14 | 2012-04-13 | Dosage regimen for sapacitabine and decitabine in combination for treating acute myeloid leukemia |
EP12717824.2A EP2696878B1 (en) | 2011-04-14 | 2012-04-13 | Dosage regimen for sapacitabine and decitabine in combination for treating acute myeloid leukemia |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2696878T3 true PL2696878T3 (pl) | 2020-01-31 |
Family
ID=46022492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL12717824T PL2696878T3 (pl) | 2011-04-14 | 2012-04-13 | Schemat dawkowania dla sapacytabiny i decytabiny w kombinacji do leczenia ostrej białaczki szpikowej |
Country Status (7)
Country | Link |
---|---|
US (2) | US10226478B2 (pl) |
EP (2) | EP3560501A1 (pl) |
JP (1) | JP6093755B2 (pl) |
ES (1) | ES2743691T3 (pl) |
HU (1) | HUE046177T2 (pl) |
PL (1) | PL2696878T3 (pl) |
WO (1) | WO2012140436A1 (pl) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL2696878T3 (pl) | 2011-04-14 | 2020-01-31 | Cyclacel Limited | Schemat dawkowania dla sapacytabiny i decytabiny w kombinacji do leczenia ostrej białaczki szpikowej |
US9872874B2 (en) | 2012-05-15 | 2018-01-23 | Cyclacel Limited | Dosage regimen for sapacitabine and seliciclib |
JP2016538310A (ja) * | 2013-11-27 | 2016-12-08 | オンコエシックス ゲーエムベーハー | チエノトリアゾロジアゼピン化合物を含む医薬製剤を用いる白血病の治療方法 |
WO2019081951A1 (en) | 2017-10-27 | 2019-05-02 | Cyclacel Limited | DOSAGE REGIME |
WO2021079129A1 (en) | 2019-10-24 | 2021-04-29 | Cyclacel Limited | Dosing regimen |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2559917B2 (ja) | 1990-06-15 | 1996-12-04 | 三共株式会社 | ピリミジンヌクレオシド誘導体 |
FI105556B (fi) | 1991-09-30 | 2000-09-15 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten pyrimidiiniukleosidijohdannaisten valmistamiseksi, joilla on kasvaimen vastaista vaikutusta |
US5824984A (en) | 1997-03-31 | 1998-10-20 | Morrow; John A. | Portable electric wire cutter |
GB9718913D0 (en) | 1997-09-05 | 1997-11-12 | Glaxo Group Ltd | Substituted oxindole derivatives |
US6403632B1 (en) | 2000-03-01 | 2002-06-11 | Bristol Myers Squibb Pharma Co | Lactam metalloprotease inhibitors |
US6835185B2 (en) | 1998-12-21 | 2004-12-28 | Micrus Corporation | Intravascular device deployment mechanism incorporating mechanical detachment |
US6462063B1 (en) | 2000-02-04 | 2002-10-08 | Fibrogen, Inc. | C-proteinase inhibitors |
US20020156033A1 (en) | 2000-03-03 | 2002-10-24 | Bratzler Robert L. | Immunostimulatory nucleic acids and cancer medicament combination therapy for the treatment of cancer |
MY164523A (en) | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
CN1315862C (zh) | 2000-05-26 | 2007-05-16 | 艾登尼科斯(开曼)有限公司 | 处理黄病毒和瘟病毒的方法和组合物 |
DE60139689D1 (de) | 2000-06-22 | 2009-10-08 | Univ Iowa Res Found | Kombination von CpG und Antikörpern gegen CD19,CD20,CD22 oder CD40 zur Prävention oder Behandlung von Krebs. |
WO2002028829A2 (en) | 2000-09-25 | 2002-04-11 | Questcor Pharmaceuticals, Inc. | Peptide deformylase inhibitors |
CN1646141B (zh) | 2000-10-18 | 2014-06-25 | 吉利德制药有限责任公司 | 用于治疗病毒感染和异常细胞增殖的修饰核苷类化合物 |
WO2002033128A2 (en) | 2000-10-18 | 2002-04-25 | Pharmasset Limited | Multiplex quantification of nucleic acids in diseased cells |
CA2430376A1 (en) | 2000-12-08 | 2002-06-13 | David J. Carini | Semicarbazides and their uses as cyclin dependent kinase inhibitors |
US6908906B2 (en) | 2001-02-09 | 2005-06-21 | Sankyo Company, Limited | Crystalline forms of pyrimidine nucleoside derivative |
JP3748536B2 (ja) | 2001-02-09 | 2006-02-22 | 三共株式会社 | ピリミジンヌクレオシド誘導体の結晶 |
US6676692B2 (en) | 2001-04-27 | 2004-01-13 | Intek Technology L.L.C. | Apparatus for delivering, repositioning and/or retrieving self-expanding stents |
EP1397137B1 (en) | 2001-05-25 | 2009-10-14 | Bristol-Myers Squibb Company | Hydantion derivatives as inhibitors of matrix metalloproteinases |
US6949558B2 (en) | 2001-11-07 | 2005-09-27 | Yale University | Enhancement of taxane-based chemotherapy by a CDK1 antagonist |
US7137993B2 (en) | 2001-12-03 | 2006-11-21 | Xtent, Inc. | Apparatus and methods for delivery of multiple distributed stents |
US8383605B2 (en) | 2002-07-30 | 2013-02-26 | Aeterna Zentaris Gmbh | Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals |
EP1628531A4 (en) | 2003-05-16 | 2010-06-30 | Idera Pharmaceuticals Inc | SYNERGISTIC TREATMENT OF CANCER BY COMMON USE OF IMMUNOMER AND CHEMOTHERAPEUTICS |
US20050014716A1 (en) | 2003-05-21 | 2005-01-20 | Wang Jin Wei | Pancreatic cancer treatment |
GB0328180D0 (en) | 2003-12-04 | 2004-01-07 | Cyclacel Ltd | Combination |
WO2008007113A2 (en) | 2006-07-14 | 2008-01-17 | Astex Therapeutics Limited | Pharmaceutical combinations |
WO2006090931A1 (ja) | 2005-02-28 | 2006-08-31 | Eisai R & D Management Co., Ltd. | スルホンアミド化合物の抗癌剤との新規併用 |
US20060212899A1 (en) | 2005-03-17 | 2006-09-21 | Ryan Steelberg | System and method for broadcast tagging |
GB0523041D0 (en) | 2005-11-11 | 2005-12-21 | Cyclacel Ltd | Combination |
GB0526419D0 (en) | 2005-12-23 | 2006-02-08 | Cyclacel Ltd | Formulation |
GB0609530D0 (en) | 2006-05-12 | 2006-06-21 | Cyclacel Ltd | Combination |
GB0625283D0 (en) | 2006-12-19 | 2007-01-24 | Cyclacel Ltd | Combination |
JP5852309B2 (ja) * | 2007-04-25 | 2016-02-03 | サイクラセル リミテッド | 増殖性疾患を治療するためのサパシタビンの使用 |
US8124593B2 (en) | 2007-11-05 | 2012-02-28 | Cyclacel Limited | Methods of treatment using sapacitabine |
CN101185629A (zh) | 2007-12-14 | 2008-05-28 | 山东蓝金生物工程有限公司 | 一种治疗实体肿瘤的地西他滨缓释剂 |
GB0808357D0 (en) | 2008-05-08 | 2008-06-18 | Cyclacel Ltd | Process |
KR101667641B1 (ko) | 2008-06-09 | 2016-10-20 | 싸이클라셀 리미티드 | 데시타빈 및 프로카인과 같은 dna 메틸전이효소 저해제와 사팍시타빈 또는 cndac의 조합 |
PL2696878T3 (pl) | 2011-04-14 | 2020-01-31 | Cyclacel Limited | Schemat dawkowania dla sapacytabiny i decytabiny w kombinacji do leczenia ostrej białaczki szpikowej |
-
2012
- 2012-04-13 PL PL12717824T patent/PL2696878T3/pl unknown
- 2012-04-13 EP EP19176614.6A patent/EP3560501A1/en not_active Withdrawn
- 2012-04-13 EP EP12717824.2A patent/EP2696878B1/en active Active
- 2012-04-13 US US14/111,430 patent/US10226478B2/en active Active
- 2012-04-13 ES ES12717824T patent/ES2743691T3/es active Active
- 2012-04-13 WO PCT/GB2012/050815 patent/WO2012140436A1/en active Application Filing
- 2012-04-13 JP JP2014504392A patent/JP6093755B2/ja not_active Expired - Fee Related
- 2012-04-13 HU HUE12717824A patent/HUE046177T2/hu unknown
-
2019
- 2019-01-16 US US16/249,274 patent/US20190314396A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US10226478B2 (en) | 2019-03-12 |
HUE046177T2 (hu) | 2020-02-28 |
US20190314396A1 (en) | 2019-10-17 |
EP2696878A1 (en) | 2014-02-19 |
JP6093755B2 (ja) | 2017-03-08 |
WO2012140436A1 (en) | 2012-10-18 |
ES2743691T3 (es) | 2020-02-20 |
JP2014510780A (ja) | 2014-05-01 |
EP2696878B1 (en) | 2019-07-10 |
EP3560501A1 (en) | 2019-10-30 |
US20140094428A1 (en) | 2014-04-03 |
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