CN1865275B - 对人b细胞肿瘤有治疗作用的人工合成的单链脱氧核苷酸 - Google Patents
对人b细胞肿瘤有治疗作用的人工合成的单链脱氧核苷酸 Download PDFInfo
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- CN1865275B CN1865275B CN2005100695764A CN200510069576A CN1865275B CN 1865275 B CN1865275 B CN 1865275B CN 2005100695764 A CN2005100695764 A CN 2005100695764A CN 200510069576 A CN200510069576 A CN 200510069576A CN 1865275 B CN1865275 B CN 1865275B
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Abstract
Description
Claims (7)
Priority Applications (42)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2005100695764A CN1865275B (zh) | 2005-05-17 | 2005-05-17 | 对人b细胞肿瘤有治疗作用的人工合成的单链脱氧核苷酸 |
BRPI0609882-7A BRPI0609882A2 (pt) | 2005-05-17 | 2006-02-13 | oligonucleotìdeo, método para induzir apoptose de células neoplásicas de célula b, método para aumentar a expressão de cd40 em células neoplásicas de célula b, método para induzir células neoplásicas de célula b a produzirem il - 10, composição farmacêutica e uso de um oligonucleotìdeo |
ES06705637T ES2433129T3 (es) | 2005-05-17 | 2006-02-13 | Oligonucleótido y composiciones que lo comprenden para tratar neoplasia de linfocitos B |
PT67056366T PT1883647E (pt) | 2005-05-17 | 2006-02-13 | Oligonucleótido e composições compreendendo o mesmo para o tratamento de neoplasma de células |
KR1020077028065A KR101346716B1 (ko) | 2005-05-17 | 2006-02-13 | 올리고뉴클레오티드 또는 이들의 기능상동체, 이들을 함유한 조성물 및 b세포 종양의 치료방법 |
PCT/CN2006/000216 WO2006122464A1 (en) | 2005-05-17 | 2006-02-13 | An oligonucleotide or its functional homologue, a composition comprising the same and a method for treating b cell neoplasm |
RU2007146706/10A RU2409672C2 (ru) | 2005-05-17 | 2006-02-13 | Олигонуклеотид или его функциональный гомолог, содержащая его композиция и способ лечения b-клеточной опухоли |
CA002609067A CA2609067A1 (en) | 2005-05-17 | 2006-02-13 | An oligonucleotide or its functional homologue, a composition comprising the same and a method for treating b cell neoplasm |
DK06705637.4T DK1883411T3 (da) | 2005-05-17 | 2006-02-13 | Oligonukleotid og sammensætninger omfattende samme til behandling af b-celle-neoplasma |
KR1020077028308A KR101294131B1 (ko) | 2005-05-17 | 2006-02-13 | 하나의 올리고뉴클레오티드 또는 그 기능상동체, 이들을 함유한 조성물 및 b세포 종양의 치료방법 |
ZA200710311A ZA200710311B (en) | 2005-05-17 | 2006-02-13 | Oligonucleotides or their functional homologues, a composition comprising the same and a method of treating B cell neoplasm |
MX2007014146A MX2007014146A (es) | 2005-05-17 | 2006-02-13 | Oligonucleotido o su homologo funcional, una composicion que comprende el mismo y un metodo para tratar neoplasma de celulas b. |
PT67056374T PT1883411E (pt) | 2005-05-17 | 2006-02-13 | Oligonucleótido e composições compreendendo o mesmo para o tratamento de neoplasma de células |
ES06705636.6T ES2442462T3 (es) | 2005-05-17 | 2006-02-13 | Oligonucleótido y composiciones que comprenden los mismos para tratar la neoplasia de células B |
DK06705636.6T DK1883647T3 (da) | 2005-05-17 | 2006-02-13 | Oligonukleotid og sammensætninger omfattende samme til behandling af b-celleneoplasme |
UAA200714106A UA94231C2 (ru) | 2005-05-17 | 2006-02-13 | Олигонуклеотиды или их функциональные гомологи, композиция, которая содержит их, и способ лечения в-клеточной опухоли |
SI200631687T SI1883411T1 (sl) | 2005-05-17 | 2006-02-13 | Oligonukleotid in sestav obsegajoäśa le-tega za zdravljenje neoplazme b celice |
BRPI0609885-1A BRPI0609885A2 (pt) | 2005-05-17 | 2006-02-13 | composição farmacêutica e uso da mesma |
US11/914,745 US8133874B2 (en) | 2005-05-17 | 2006-02-13 | Oligonucleotide or its functional homologue, a composition comprising the same and a method of treating B cell neoplasm |
NZ563582A NZ563582A (en) | 2005-05-17 | 2006-02-13 | An oligonucleotide or its functional homologue, a composition comprising the same and a method for treating B cell neoplasm |
EP06705637.4A EP1883411B1 (en) | 2005-05-17 | 2006-02-13 | Oligonucleotide and compositions comprising the same for treating B cell neoplasm |
EP06705636.6A EP1883647B1 (en) | 2005-05-17 | 2006-02-13 | Oligonucleotide and compositions comprising the same for treating B cell neoplasm |
AU2006246898A AU2006246898B2 (en) | 2005-05-17 | 2006-02-13 | An oligonucleotide or its functional homologue, a composition comprising the same and a method for treating B cell neoplasm |
RU2007146705/14A RU2413519C2 (ru) | 2005-05-17 | 2006-02-13 | Олигонуклеотиды или их функциональные гомологи, содержащая их композиция и способ лечения в-клеточной опухоли |
JP2008511531A JP4837033B2 (ja) | 2005-05-17 | 2006-02-13 | オリゴヌクレオチドまたはその機能的相同体、それらを含有する組成物およびb細胞腫瘍を治療する方法 |
US11/914,744 US20090202567A1 (en) | 2005-05-17 | 2006-02-13 | Oligonucleotides or their functional homologues, a composition comprising the same and a method of treating b cell neoplasm |
SI200631728T SI1883647T1 (sl) | 2005-05-17 | 2006-02-13 | Oligonukleotid in obsegajoča ga sestava za zdravljenje B celične neoplazme |
ZA200710312A ZA200710312B (en) | 2005-05-17 | 2006-02-13 | An oligonucleotide or its functional homologue, a composition comprising the same and a method for treating B Cell neoplasm |
PL06705636T PL1883647T3 (pl) | 2005-05-17 | 2006-02-13 | Oligonukleotyd i zawierające go mieszaniny do leczenia nowotworów komórek B |
JP2008511532A JP4837034B2 (ja) | 2005-05-17 | 2006-02-13 | オリゴヌクレオチドまたはその機能的相同体、それらを含有する組成物およびb細胞腫瘍を治療するための方法 |
PL06705637T PL1883411T3 (pl) | 2005-05-17 | 2006-02-13 | Oligonukleotyd oraz kompozycja zawierająca oligonukleotyd do stosowania w leczeniu nowotworu komórek B |
MX2007014145A MX2007014145A (es) | 2005-05-17 | 2006-02-13 | Oligonucleotidos o sus homologos funcionales, una composicion que comprende los mismos y un metodo de tratamiento de neoplasma de celulas b. |
CA2609062A CA2609062C (en) | 2005-05-17 | 2006-02-13 | Oligonucleotides or their functional homologues, a composition comprising the same and a method of treating b cell neoplasm |
AU2006246897A AU2006246897B2 (en) | 2005-05-17 | 2006-02-13 | Oligonucleotides or their functional homologues, a composition comprising the same and a method of treating B cell neoplasm |
UAA200714103A UA91057C2 (ru) | 2005-05-17 | 2006-02-13 | Олигонуклеотид или его функциональный гомолог, композиция, содержащая его, и способ лечения в-клеточной опухоли |
PCT/CN2006/000215 WO2006122463A1 (en) | 2005-05-17 | 2006-02-13 | Oligonucleotides or their functional homologues, a composition comprising the same and a method of treating b cell neoplasm |
IL187281A IL187281A (en) | 2005-05-17 | 2007-11-08 | Use of a pharmaceutical composition comprising an oligonucleotide in the preparation of medicaments for treating b cell neoplasm, and ex vivo methods of inducing apoptosis of b-cell neoplastic cells, comprising contacting said cells with said composition |
IL187249A IL187249A (en) | 2005-05-17 | 2007-11-08 | Use of compositions comprising oligonucleotides in the preparation of medicaments for treating b cell neoplasms, ex vivo methods comprising the use of said compositions and pharmaceutical compositions comprising the same |
HK08108302.8A HK1113318A1 (en) | 2005-05-17 | 2008-07-28 | Oligonucleotide and compositions comprising the same for treating b cell neoplasm |
HK08108303.7A HK1112745A1 (en) | 2005-05-17 | 2008-07-28 | Oligonucleotide and compositions comprising the same for treating b cell neoplasm |
US13/310,595 US8450292B2 (en) | 2005-05-17 | 2011-12-02 | Oligonucleotides or their functional homologues, a composition comprising the same and a method of treating B cell neoplasm |
CY20141100024T CY1114844T1 (el) | 2005-05-17 | 2014-01-13 | Ολιγο-νουκλεοτιδιο (oligonucleotide) και συνθεσεις που το περιλαμβανουν για την θεραπεια νεοπλασματος β κυτταρων |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2005100695764A CN1865275B (zh) | 2005-05-17 | 2005-05-17 | 对人b细胞肿瘤有治疗作用的人工合成的单链脱氧核苷酸 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1865275A CN1865275A (zh) | 2006-11-22 |
CN1865275B true CN1865275B (zh) | 2011-06-15 |
Family
ID=37424439
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2005100695764A Active CN1865275B (zh) | 2005-05-17 | 2005-05-17 | 对人b细胞肿瘤有治疗作用的人工合成的单链脱氧核苷酸 |
Country Status (22)
Country | Link |
---|---|
US (3) | US20090202567A1 (zh) |
EP (2) | EP1883647B1 (zh) |
JP (2) | JP4837033B2 (zh) |
KR (2) | KR101294131B1 (zh) |
CN (1) | CN1865275B (zh) |
AU (2) | AU2006246897B2 (zh) |
BR (2) | BRPI0609885A2 (zh) |
CA (2) | CA2609062C (zh) |
CY (1) | CY1114844T1 (zh) |
DK (2) | DK1883647T3 (zh) |
ES (2) | ES2433129T3 (zh) |
HK (2) | HK1112745A1 (zh) |
IL (2) | IL187281A (zh) |
MX (2) | MX2007014145A (zh) |
NZ (1) | NZ563582A (zh) |
PL (2) | PL1883411T3 (zh) |
PT (2) | PT1883647E (zh) |
RU (2) | RU2413519C2 (zh) |
SI (2) | SI1883411T1 (zh) |
UA (2) | UA91057C2 (zh) |
WO (2) | WO2006122464A1 (zh) |
ZA (2) | ZA200710311B (zh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110182880A1 (en) * | 2008-06-18 | 2011-07-28 | Oliver Von Stein | Combination Therapies Against Cancer |
CN101643496B (zh) * | 2008-08-07 | 2015-09-09 | 长春华普生物技术有限公司 | 一种具有免疫抑制功能的寡核苷酸 |
US20110280934A1 (en) * | 2008-11-04 | 2011-11-17 | Asa Karlsson | Increased Expression of Specific Antigens |
DK3165607T3 (da) * | 2010-12-21 | 2021-05-31 | Index Pharmaceuticals Ab | Biologisk aktive oligonukleotider, der kan modulere immunsystemet |
WO2012084991A1 (en) * | 2010-12-21 | 2012-06-28 | Index Pharmaceuticals Ab | Biologically active oligonucleotides capable of modulating the immune system ii |
CN106893724B (zh) * | 2015-12-17 | 2023-05-02 | 苏州派动生物技术有限公司 | 具有抗原增效作用和肿瘤治疗作用的寡核苷酸 |
WO2021249116A1 (en) | 2020-06-10 | 2021-12-16 | Sichuan Clover Biopharmaceuticals, Inc. | Coronavirus vaccine compositions, methods, and uses thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1526718A (zh) * | 2003-03-05 | 2004-09-08 | 长春华普生物技术有限公司 | 抗病毒和抗肿瘤的含CpG单链脱氧寡核苷酸 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
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MXPA02003108A (es) * | 1999-09-25 | 2003-10-14 | Univ Iowa Res Found | Acidos nucleicos inmunoestimuladores. |
CA2404365A1 (en) * | 2000-03-31 | 2001-10-11 | Idec Pharmaceutical Corporation | Combined use of anti-cytokine antibodies or antagonists and anti-cd20 for the treatment of b cell lymphoma |
PT1296714E (pt) * | 2000-06-22 | 2009-10-15 | Coley Pharm Gmbh | Combinação de cpg e anticorpos dirigidos contra cd19, cd20, cd22 ou cd40 para o tratamento ou prevenção do cancro |
US20040009156A1 (en) | 2001-10-12 | 2004-01-15 | Christoph Reinhard | Antisense therapy using oligonucleotides that target human kinesin genes for treatment of cancer |
ES2528384T3 (es) * | 2001-12-12 | 2015-02-09 | The Government Of The United States Of America, As Represented By The Secretary Department Of Healt | Métodos de utilización de inhibidores del receptor de adenosina para potenciar la respuesta inmunitaria y la inflamación |
US7576066B2 (en) * | 2002-07-03 | 2009-08-18 | Coley Pharmaceutical Group, Inc. | Nucleic acid compositions for stimulating immune responses |
DE10258677A1 (de) | 2002-12-13 | 2004-06-24 | Elez, Vera, Dr. | Kombinations-antisense-Oligonukleotid-Krebstherapie |
CN100439386C (zh) | 2003-03-05 | 2008-12-03 | 长春华普生物技术有限公司 | 增强蛋白类疫苗免疫效果的含CpG单链脱氧寡核苷酸 |
ATE502949T1 (de) | 2003-07-25 | 2011-04-15 | Changchun Huapu Biotechnology Co Ltd | Das künstliche cpg single strand deoxidation- oligonukleotid und dessen antivirale anwendungen |
JP4513879B2 (ja) | 2008-03-05 | 2010-07-28 | ソニー株式会社 | 像ぶれ補正装置、レンズ鏡筒装置及びカメラ装置 |
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2005
- 2005-05-17 CN CN2005100695764A patent/CN1865275B/zh active Active
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2006
- 2006-02-13 ES ES06705637T patent/ES2433129T3/es active Active
- 2006-02-13 PT PT67056366T patent/PT1883647E/pt unknown
- 2006-02-13 DK DK06705636.6T patent/DK1883647T3/da active
- 2006-02-13 BR BRPI0609885-1A patent/BRPI0609885A2/pt not_active IP Right Cessation
- 2006-02-13 MX MX2007014145A patent/MX2007014145A/es active IP Right Grant
- 2006-02-13 WO PCT/CN2006/000216 patent/WO2006122464A1/en active Application Filing
- 2006-02-13 US US11/914,744 patent/US20090202567A1/en not_active Abandoned
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- 2006-02-13 RU RU2007146705/14A patent/RU2413519C2/ru not_active IP Right Cessation
- 2006-02-13 UA UAA200714103A patent/UA91057C2/ru unknown
- 2006-02-13 EP EP06705636.6A patent/EP1883647B1/en not_active Not-in-force
- 2006-02-13 ES ES06705636.6T patent/ES2442462T3/es active Active
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- 2006-02-13 KR KR1020077028308A patent/KR101294131B1/ko not_active IP Right Cessation
- 2006-02-13 AU AU2006246897A patent/AU2006246897B2/en not_active Ceased
- 2006-02-13 ZA ZA200710311A patent/ZA200710311B/xx unknown
- 2006-02-13 UA UAA200714106A patent/UA94231C2/ru unknown
- 2006-02-13 SI SI200631687T patent/SI1883411T1/sl unknown
- 2006-02-13 WO PCT/CN2006/000215 patent/WO2006122463A1/en active Application Filing
- 2006-02-13 ZA ZA200710312A patent/ZA200710312B/xx unknown
- 2006-02-13 DK DK06705637.4T patent/DK1883411T3/da active
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- 2006-02-13 AU AU2006246898A patent/AU2006246898B2/en not_active Ceased
- 2006-02-13 PL PL06705637T patent/PL1883411T3/pl unknown
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- 2006-02-13 JP JP2008511531A patent/JP4837033B2/ja not_active Expired - Fee Related
- 2006-02-13 PL PL06705636T patent/PL1883647T3/pl unknown
- 2006-02-13 US US11/914,745 patent/US8133874B2/en active Active
- 2006-02-13 JP JP2008511532A patent/JP4837034B2/ja active Active
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- 2006-02-13 RU RU2007146706/10A patent/RU2409672C2/ru not_active IP Right Cessation
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2007
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2008
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- 2008-07-28 HK HK08108302.8A patent/HK1113318A1/xx not_active IP Right Cessation
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2011
- 2011-12-02 US US13/310,595 patent/US8450292B2/en not_active Expired - Fee Related
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CN1526718A (zh) * | 2003-03-05 | 2004-09-08 | 长春华普生物技术有限公司 | 抗病毒和抗肿瘤的含CpG单链脱氧寡核苷酸 |
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Address after: High tech Zone of Jilin province Changchun Chaoqun street 130103 No. 191 incubator building block A room 306 Patentee after: CHANGCHUN HUAPU BIOTECHNOLOGY CO.,LTD. Address before: 130021 Xinmin Street, Jilin, Changchun, China 4-28/1102-54 Patentee before: CHANGCHUN HUAPU BIOTECHNOLOGY Co.,Ltd. |
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Address after: Room 1208-1210, block B, Zhongdan Ecological Life Science Industrial Park, no.3-1, xinjinhu Road, high tech Industrial Development Zone, Nanjing, Jiangsu 210000 Patentee after: Nanjing Huapu Biotechnology Co.,Ltd. Address before: Room 306, block a, incubation building, 191 Chaoqun street, high tech Zone, Jilin Province Patentee before: CHANGCHUN HUAPU BIOTECHNOLOGY Co.,Ltd. |
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Address after: 214142 Room 301, No. 35-501, Changjiang South Road, Xinwu District, Wuxi City, Jiangsu Province Patentee after: Huapu Biotechnology (Jiangsu) Co.,Ltd. Address before: Room 1208-1210, block B, Zhongdan Ecological Life Science Industrial Park, no.3-1, xinjinhu Road, high tech Industrial Development Zone, Nanjing, Jiangsu 210000 Patentee before: Nanjing Huapu Biotechnology Co.,Ltd. |
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Address after: 051430 7-9/F, Building A2, No. 769, Taihang South Street, Shijiazhuang Hi tech Industrial Development Zone, Hebei Province Patentee after: Huapu Biotechnology (Hebei) Co.,Ltd. Address before: 214142 Room 301, No. 35-501, Changjiang South Road, Xinwu District, Wuxi City, Jiangsu Province Patentee before: Huapu Biotechnology (Jiangsu) Co.,Ltd. |